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Articles

Psychedelic Experiences and Mindfulness are Associated with Improved Wellbeing

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Pages 123-133 | Received 18 Aug 2021, Accepted 25 Jan 2022, Published online: 19 Apr 2022

References

  • Aday, J. S., C. M. Mitzkovitz, E. K. Bloesch, C. C. Davoli, and A. K. Davis. 2020. Long-term effects of psychedelic drugs: A systematic review. Neuroscience and Biobehavioral Reviews 113:179–89. doi:10.1016/j.neubiorev.2020.03.017.
  • Anderson, T., R. Petranker, D. Rosenbaum, C. R. Weissman, L.-A. Dinh-Williams, K. Hui, E. Hapke, and N. A. S. Farb. 2019. Microdosing psychedelics: Personality, mental health, and creativity differences in microdosers. Psychopharmacology 236 (2):731–40. doi:10.1007/s00213-018-5106-2.
  • Baer, R. A., E. L. B. Lykins, and J. R. Peters. 2012. Mindfulness and self-compassion as predictors of psychological wellbeing in long-term meditators and matched nonmeditators. The Journal of Positive Psychology 7 (3):230–38. doi:10.1080/17439760.2012.674548.
  • Baer, R. A., G. T. Smith, J. Hopkins, J. Krietemeyer, and L. Toney. 2006. Using self-report assessment methods to explore facets of mindfulness. Assessment 13 (1):27–45. doi:10.1177/1073191105283504.
  • Barrett, F. S., and R. R. Griffiths. 2018. Classic Hallucinogens and Mystical Experiences: Phenomenology and Neural Correlates. Current Topics in Behavioral Neurosciences 36:393–430. doi:10.1007/7854_2017_474.
  • Barrett, F. S., M. W. Johnson, and R. R. Griffiths. 2015. Validation of the revised mystical experience questionnaire in experimental sessions with psilocybin. Journal of Psychopharmacology 29 (11):1182–90. doi:10.1177/0269881115609019.
  • Barrett, F. S., M. W. Johnson, and R. R. Griffiths. 2017. Psilocybin in long-term meditators: Effects on default mode network functional connectivity and retrospective ratings of qualitative experience. Drug and Alcohol Dependence 171 (2):e15–e16. doi:10.1007/s00213-018-5106-2.
  • Bester, E., P. Naidoo, and A. Botha. 2016. The role of mindfulness in the relationship between life satisfaction and spiritual wellbeing amongst the elderly. Social Work 52(2. doi:10.15270/52-2-503.
  • Birtwell, K., K. Williams, H. van Marwijk, C. J. Armitage, and D. Sheffield. 2019. An exploration of formal and informal mindfulness practice and associations with wellbeing. Mindfulness 10 (1):89–99. doi:10.1007/s12671-018-0951-y.
  • Bøhling, F. 2017. Psychedelic pleasures: An affective understanding of the joys of tripping. The International Journal on Drug Policy 49:133–43. doi:10.1016/j.drugpo.2017.07.017.
  • Brown, K. W., and R. M. Ryan. 2003. The benefits of being present: Mindfulness and its role in psychological well-being. Journal of Personality and Social Psychology 84 (4):822–48. doi:10.1037/0022-3514.84.4.822.
  • Campos, D., A. Cebolla, S. Quero, J. Bretón-López, C. Botella, J. Soler, J. García-Campayo, M. Demarzo, and R. M. Baños. 2016. Meditation and happiness: Mindfulness and self-compassion may mediate the meditation–happiness relationship. Personality and Individual Differences 93:80–85. doi:10.1016/j.paid.2015.08.040.
  • Carhart-Harris, R. L., R. Leech, P. J. Hellyer, M. Shanahan, A. Feilding, E. Tagliazucchi, D. R. Chialvo, and D. Nutt. 2014. The entropic brain: A theory of conscious states informed by neuroimaging research with psychedelic drugs. Frontiers in Human Neuroscience 8:20. doi:10.3389/fnhum.2014.00020.
  • Davidson, J. M. 1976. The physiology of meditation and mystical states of consciousness. Perspectives in Biology and Medicine 19 (3):345–80. doi:10.1353/pbm.1976.0042.
  • Davis, A. K., J. M. Clifton, E. G. Weaver, E. S. Hurwitz, M. W. Johnson, and R. R. Griffiths. 2020. Survey of entity encounter experiences occasioned by inhaled N,N-dimethyltryptamine: Phenomenology, interpretation, and enduring effects. Journal of Psychopharmacology 34 (9):1008–20. doi:10.1177/0269881120916143.
  • de Castro, J. M. 2015. Meditation has stronger relationships with mindfulness, kundalini, and mystical experiences than yoga or prayer. Consciousness and Cognition 35:115–27. doi:10.1016/j.concog.2015.04.022.
  • Diener, E. D., R. A. Emmons, R. J. Larsen, and S. Griffin. 1985. The satisfaction with life scale. Journal of Personality Assessment 49 (1):71–75. doi:10.1207/s15327752jpa4901_13.
  • Doblin, R. E., M. Christiansen, L. Jerome, and B. Burge. 2019. The past and future of psychedelic science: an introduction to this issue. Journal of Psychoactive Drugs 51 (2):93–97. doi:10.1080/02791072.2019.1606472.
  • Erowid Psychoactive Vaults. (2018, March 12). Erowid. https://www.erowid.org/psychoactives/psychoactives.shtml
  • Forstmann, M., D. A. Yudkin, A. M. B. Prosser, S. M. Heller, and M. J. Crockett. 2020. Transformative experience and social connectedness mediate the mood-enhancing effects of psychedelic use in naturalistic settings. Proceedings of the National Academy of Sciences of the United States of America 117 (5):2338–46. doi:10.1073/pnas.1918477117.
  • Garland, E. L., N. A. Farb, P. R. Goldin, and B. L. Fredrickson. 2015. The Mindfulness-to-Meaning Theory: Extensions, Applications, and Challenges at the Attention–Appraisal–Emotion Interface. Psychological Inquiry 26 (4):377–87. doi:10.1080/1047840X.2015.1092493.
  • Garland, E., S. Gaylord, and J. Park. 2009. The role of mindfulness in positive reappraisal. Explore 5 (1):37–44. doi:10.1016/j.explore.2008.10.001.
  • Garland, E. L., A. W. Hanley, P. R. Goldin, and J. J. Gross. 2017. Testing the mindfulness-to-meaning theory: Evidence for mindful positive emotion regulation from a reanalysis of longitudinal data. PloS One 12 (12):e0187727. doi:10.1016/j.drugpo.2017.07.017.
  • Glück, J., S. König, K. Naschenweng, U. Redzanowski, L. Dorner, I. Straßer, and W. Wiedermann. 2013. How to measure wisdom: Content, reliability, and validity of five measures. Frontiers in Psychology 4:405. doi:10.3389/fpsyg.2013.00405.
  • Goldberg, S. B., R. P. Tucker, P. A. Greene, R. J. Davidson, B. E. Wampold, D. J. Kearney, and T. L. Simpson. 2018. Mindfulness-based interventions for psychiatric disorders: A systematic review and meta-analysis. Clinical Psychology Review 59:52–60. doi:10.1016/j.cpr.2017.10.011.
  • Goyal, M., S. Singh, E. M. S. Sibinga, N. F. Gould, A. Rowland-Seymour, R. Sharma, Z. Berger, D. Sleicher, D. D. Maron, H. M. Shihab, et al. 2014. Meditation programs for psychological stress and well-being: A systematic review and meta-analysis. JAMA Internal Medicine 174 (3):357–68. doi:10.1001/jamainternmed.2013.13018.
  • Griffiths, R. R., M. W. Johnson, W. A. Richards, B. D. Richards, R. Jesse, K. A. MacLean, F. S. Barrett, M. P. Cosimano, and M. A. Klinedinst. 2018. Psilocybin-occasioned mystical-type experience in combination with meditation and other spiritual practices produces enduring positive changes in psychological functioning and in trait measures of prosocial attitudes and behaviors. Journal of Psychopharmacology 32 (1):49–69. doi:10.1177/0269881117731279.
  • Griffiths, R. R., M. W. Johnson, W. A. Richards, B. D. Richards, U. McCann, and R. Jesse. 2011. Psilocybin occasioned mystical-type experiences: Immediate and persisting dose-related effects. Psychopharmacology 218 (4):649–65. doi:10.1007/s00213-011-2358-5.
  • Griffiths, R., W. Richards, M. Johnson, U. McCann, and R. Jesse. 2008. Mystical-type experiences occasioned by psilocybin mediate the attribution of personal meaning and spiritual significance 14 months later. Journal of Psychopharmacology 22 (6):621–32. doi:10.1177/0269881108094300.
  • Griffiths, R. R., W. A. Richards, U. McCann, and R. Jesse. 2006. Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance. Psychopharmacology 187(3):268–83. discussion 284–292. doi:10.1007/s00213-006-0457-5.
  • Gu, J., C. Strauss, R. Bond, and K. Cavanagh. 2015. How do mindfulness-based cognitive therapy and mindfulness-based stress reduction improve mental health and wellbeing? A systematic review and meta-analysis of mediation studies. Clinical Psychology Review 37:1–12. doi:10.1016/j.cpr.2015.01.006.
  • Gunaratana, H. 1993. Sati: Mindfulness in Plain English. Boston, MA: California Buddhist Vihara Society.
  • Haijen, E. C. H. M., M. Kaelen, L. Roseman, C. Timmermann, H. Kettner, S. Russ, D. Nutt, R. E. Daws, A. D. G. Hampshire, R. Lorenz, et al. 2018. Predicting responses to psychedelics: a prospective study. Frontiers in Pharmacology 9:897. doi:10.3389/fphar.2018.00897.
  • Hartogsohn, I. 2018. The meaning-enhancing properties of psychedelics and their mediator role in psychedelic therapy, spirituality, and creativity. Frontiers in Neuroscience 12:129. doi:10.3389/fnins.2018.00129.
  • Henry, J. D., and J. R. Crawford. 2005. The short-form version of the depression anxiety stress scales (DASS-21): Construct validity and normative data in a large non-clinical sample. The British Journal of Clinical Psychology/the British Psychological Society 44 (2):227–39. doi:10.1348/014466505X29657.
  • Holze, F., P. Vizeli, F. Müller, L. Ley, R. Duerig, N. Varghese, A. Eckert, S. Borgwardt, and M. E. Liechti. 2020. Distinct acute effects of LSD, MDMA, and D-amphetamine in healthy subjects. Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology 45 (3):462–71. doi:10.1038/s41386-019-0569-3.
  • Johnson, M. W., P. S. Hendricks, F. S. Barrett, and R. R. Griffiths. 2019. Classic psychedelics: An integrative review of epidemiology, therapeutics, mystical experience, and brain network function. Pharmacology & Therapeutics 197:83–102. doi:10.1016/j.pharmthera.2018.11.010.
  • Johnson, M., W. Richards, and R. Griffiths. 2008. Human hallucinogen research: Guidelines for safety. Journal of Psychopharmacology 22 (6):603–20. doi:10.1177/0269881108093587.
  • Josipovic, Z. 2014. Neural correlates of nondual awareness in meditation. Annals of the New York Academy of Sciences 1307 (1):9–18. doi:10.1111/nyas.12261.
  • Jungaberle, H., S. Thal, A. Zeuch, A. Rougemont-Bücking, M. von Heyden, H. Aicher, and M. Scheidegger. 2018. Positive psychology in the investigation of psychedelics and entactogens: A critical review. Neuropharmacology 142:179–99. doi:10.1016/j.neuropharm.2018.06.034.
  • Kabat-Zinn, J. 1982. An outpatient program in behavioral medicine for chronic pain patients based on the practice of mindfulness meditation: Theoretical considerations and preliminary results. General Hospital Psychiatry 4 (1):33–47. doi:10.1016/0163-8343(82)90026-3.
  • Kabat-Zinn, J., and T. N. Hanh. 2009. Full catastrophe living: using the wisdom of your body and mind to face stress, pain, and illness. New York: Random House Publishing Group. Accessed January 2019. https://play.google.com/store/books/details?id=TVsrK0sjGiUC
  • Liechti, M. E., P. C. Dolder, and Y. Schmid. 2017. Alterations of consciousness and mystical-type experiences after acute LSD in humans. Psychopharmacology 234 (9–10):1499–510. doi:10.1007/s00213-016-4453-0.
  • Lyvers, M., and M. Meester. 2012. Illicit use of LSD or psilocybin, but not MDMA or nonpsychedelic drugs, is associated with mystical experiences in a dose-dependent manner. Journal of Psychoactive Drugs 44 (5):410–17. doi:10.1080/02791072.2012.736842.
  • MacLean, K. A., M. W. Johnson, and R. R. Griffiths. 2011. Mystical experiences occasioned by the hallucinogen psilocybin lead to increases in the personality domain of openness. Journal of Psychopharmacology 25 (11):1453–61. doi:10.1177/0269881111420188.
  • Mason, N. L., P. C. Dolder, and K. P. C. Kuypers. 2020. Reported effects of psychedelic use on those with low well-being given various emotional states and social contexts. Drug Science, Policy and Law 6:2050324519900068. doi:10.1177/2050324519900068.
  • Millière, R., R. L. Carhart-Harris, L. Roseman, F.-M. Trautwein, and A. Berkovich-Ohana. 2018. Psychedelics, Meditation, and Self-Consciousness. Frontiers in Psychology 9:1475. doi:10.3389/fpsyg.2018.01475.
  • Montero-Marin, J., M. Puebla-Guedea, P. Herrera-Mercadal, A. Cebolla, J. Soler, M. Demarzo, C. Vazquez, F. Rodríguez-Bornaetxea, and J. García-Campayo. 2016. Psychological effects of a 1-month meditation retreat on experienced meditators: the role of non-attachment. Frontiers in Psychology 7 (1935). doi: 10.3389/fpsyg.2016.01935.
  • Móró, L., K. Simon, I. Bárd, and J. Rácz. 2011. Voice of the psychonauts: Coping, life purpose, and spirituality in psychedelic drug users. Journal of Psychoactive Drugs 43 (3):188–98. doi:10.1080/02791072.2011.605661.
  • Nichols, D. E. 2016. Psychedelics. Pharmacological Reviews 68 (2):264–355. doi:10.1124/pr.115.011478.
  • Parsons, C. E., C. Crane, L. J. Parsons, L. O. Fjorback, and W. Kuyken. 2017. Home practice in mindfulness-based cognitive therapy and mindfulness-based stress reduction: A systematic review and meta-analysis of participants’ mindfulness practice and its association with outcomes. Behaviour Research and Therapy 95:29–41. doi:10.1016/j.brat.2017.05.004.
  • Qualtrics, I. 2013. Qualtrics. Provo, UT, USA.
  • Raglan, G. B. 2014. Decision making, mindfulness and mood: How mindfulness techniques can reduce the impact of biases and heuristics through improved decision making and positive affect. Journal of Depression and Anxiety 04 (1). doi: 10.4172/2167-1044.1000168.
  • Roberts, C. A., I. Osborne-Miller, J. Cole, S. H. Gage, and P. Christiansen. 2020. Perceived harm, motivations for use and subjective experiences of recreational psychedelic “magic” mushroom use. Journal of Psychopharmacology 34 (9):999–1007. doi:10.1177/0269881120936508.
  • Schmidt, A. F., and C. Finan. 2018. Linear regression and the normality assumption. Journal of Clinical Epidemiology 98:146–51. doi:10.1016/j.jclinepi.2017.12.006.
  • Segal, Z. V., J. M. G. Williams, and J. D. Teasdale. 2001. Mindfulness-based cognitive therapy for depression, first edition: a new approach to preventing relapse. New York: Guilford Publications. https://play.google.com/store/books/details?id=VkvGwAEACAAJ.
  • Shapiro, S. L., K. W. Brown, C. Thoresen, and T. G. Plante. 2011. The moderation of Mindfulness-based stress reduction effects by trait mindfulness: Results from a randomized controlled trial. Journal of Clinical Psychology 67 (3):267–77. doi:10.1002/jclp.20761.
  • Smigielski, L., M. Kometer, M. Scheidegger, R. Krähenmann, T. Huber, and F. X. Vollenweider. 2019a. Characterization and prediction of acute and sustained response to psychedelic psilocybin in a mindfulness group retreat. Scientific Reports 9 (1):14914. doi:10.1038/s41598-019-50612-3.
  • Smigielski, L., M. Scheidegger, M. Kometer, and F. X. Vollenweider. 2019b. Psilocybin-assisted mindfulness training modulates self-consciousness and brain default mode network connectivity with lasting effects. NeuroImage 196:207–15. doi:10.1016/j.neuroimage.2019.04.009.
  • Spinelli, C., M. Wisener, and B. Khoury. 2019. Mindfulness training for healthcare professionals and trainees: A meta-analysis of randomized controlled trials. Journal of Psychosomatic Research 120:29–38. doi:10.1016/j.jpsychores.2019.03.003.
  • Steger, M. F., P. Frazier, S. Oishi, and M. Kaler. 2006. The meaning in life questionnaire: Assessing the presence of and search for meaning in life. Journal of Counseling Psychology 53 (1):80–93. doi:10.1037/0022-0167.53.1.80.
  • Vago, D. R., and D. A. Silbersweig. 2012. Self-awareness, self-regulation, and self-transcendence (S-ART): A framework for understanding the neurobiological mechanisms of mindfulness. Frontiers in Human Neuroscience 6:296. doi:10.3389/fnhum.2012.00296.
  • Van Lente, E., and M. J. Hogan. 2020. Understanding the nature of oneness experience in meditators using collective intelligence methods. Frontiers in Psychology 11:2092. doi:10.3389/fpsyg.2020.02092.
  • Verhaeghen, P. 2020. The examined life is wise living: the relationship between mindfulness, wisdom, and the moral foundations. Journal of Adult Development 27 (4):305–22. doi:10.1007/s10804-019-09343-y.
  • Watson, D., L. A. Clark, and A. Tellegen. 1988. Development and validation of brief measures of positive and negative affect: The PANAS scales. Journal of Personality and Social Psychology 54 (6):1063–70. doi:10.1037//0022-3514.54.6.1063.
  • White, H. 1980. A heteroskedasticity-consistent covariance matrix estimator and a direct test for heteroskedasticity. Econometrica 48 (4):817. doi:10.2307/1912934.
  • Winstock, A. R. (2019). Global Drug Survey 2019. Global Drug Survey. Accessed December 2019. https://www.globaldrugsurvey.com/gds-2019/
  • Yockey, R. A., R. A. Vidourek, and K. A. King. 2020. Trends in LSD use among US adults: 2015–2018. Drug and Alcohol Dependence 212:108071. doi:10.1016/j.drugalcdep.2020.108071.

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