33
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Cardioprotective effects of the MR contrast agent MnDPDP and its metabolite MnPLED upon reperfusion of the ischemic porcine myocardium

, , , , , , , & show all
Pages 540-547 | Published online: 09 Jul 2009

References

  • ARCHIBALD F. S. & FRIDOVICH I.: The scavenging of su-peroxide radicals by manganous complexes. In vitro. Arch. Biochem. Biophys. 214 (1982), 452.
  • ASPLUND A., GRANT D. & KARLSSON J. 0. G.: Mangafodi-pir (MnDPDP)- and MnC12-induced endothelium-depend-ent relaxation in bovine mesenteric arteries. J. Pharmacol. Exp. Ther. 271 (1994), 609.
  • BARANDIER C. E., BOUCHER F R. & DE LEIRES J. P: Manga-nese reduces myocardial reperfusion injury on isolated rat heart. J. Mol. Cell Cardiol. 30 (1988), 837.
  • BATINIC-HABERLE I., BENOV L., SPASOJEVIC I. & FRIDOVICH I.: The ortho effects makes manganese(III)meso-tetrakis-(N-methylpyridinium-2-ypporphyrin a powerful and poten-tially useful superoxide dismutase mimic. J. Biol. Chem. 273 (1998), 24521.
  • BAUDRY M., ETIENNE S., BRUCE A., PALUCKI M., JACOBSEN E. & MALFROY B.: Salen-manganese complexes are su-peroxide dismutase-mimics. Biochem. Biophys. Res. Com-mun. 192 (1993), 964.
  • BLACK S. C., SCHASTEEN C. S., WEISS R. H., RILEY D. R, DRISCOLL E. M. & LUCCHESI B. R.: Inhibition of in vivo myocardial ischemic and reperfusion injury by synthetic manganese-based superoxide dismutase mimetic. J. Pharm-acol. Exp. Ther. 270 (1994), 1208.
  • BRAUNWALD E. & KLONER R. A.: Myocardial reperfusion. A double-edged sword? J. Clin. Invest. 76 (1985), 1713.
  • BREMERICH J., SAEED M., ARHEDEN H., HIGGINS C. B. & WENDLAND M. F: Differentiation between normal and in-farcted myocardium by myocardial cellular uptake of manganese. Radiology 216 (2000), 524.
  • BRUROK H., ARDENKLER-LARSEN J. H., HANSSON G. et al.: Manganese dipyridoxyl diphosphate. MRI contrast agent with antioxidant and cardioprotective properties? Biochem. Biophys. Res. Commun. 254 (1999), 768.
  • BRUROK H., SKOGLUND T., BERG K., SKARRA S., KARLSSON J. 0. G. & JYNGE P.: Myocardial manganese elevation and proton relaxivity enhancement with manganese dipyridoxyl diphosphate. Ex vivo assessments in normally perfused and ischemic guinea pig hearts. NMR Biomed. 12 (1999), 364.
  • CHEN Z., Sru B., Ho Y. S. et al.: Overexpression of MnSOD protects against myocardial ischemia/reperfusion injury in transgenic mice. J. Mol. Cell Cardiol. 30 (1998), 2281.
  • CLELAND J. G., SWEDBERG K. & POOLE-WILSON P A.: Suc-cesses and failures of current treatment of heart failure. Lancet 352 (1998), Suppl. 1, 19.
  • CzAPsxr G. & GOLDSTEIN S.: Requirements for SOD mimics operating in vitro to work also in vivo. Free Radic. Res. Commun. 12–13 (1991), 167.
  • DOCTROW S. R., HUFFMAN K., MARCUS C. B. et al.: Salen-manganese complexes. Combined superoxide dismutase/ catalase mimics with broad pharmacological efficacy. Adv. Pharmacol. 38 (1997), 247.
  • DUNCKER D. J., KLASSEN C. L., ISHIBASHI Y, HERRLINGER S. H., PAVEK T. J. & BACHE R. J.: Effect of temperature on myocardial infarction in swine. Am. J. Physiol. 270 (1996), H1189.
  • FAULKNER K. M., LIOCHEV S. I. & FRIDOVICH I.: Stable Mn(III)porphyrins mimic superoxide dismutase in vitro and substitute for it in vivo. J. Biol. Chem. 269 (1994), 23471.
  • FRENCH J. K. & WHITE H. D.: Left ventricular function following thrombolytic therapy for myocardial infarction. Clin. Exp. Pharmacol. Physiol. 22 (1995), 173.
  • FRIDOVICH I.: Oxygen toxicity. A radical explanation. J. Exp. Biol. 201 (1998), 1203.
  • GARLICK P B., DAVIES M. J., HEARSE D. J. & SLATER T. E: Direct detection of free radicals in the reperfused rat heart using electron spin resonance spectroscopy. Circ. Res. 61 (1987), 757.
  • GIVERTZ M. M. & COLUCCI W. S.: New targets for heart-failure therapy. Endothelin inflammatory cytokines, and oxidative stress. Lancet 352 (1998), Suppl. 1, 34.
  • HARDY M. M., FLICKINGER A. G., RILEY D. P, WEISS R. H. & RYAN U. S.: Superoxide dismutase mimetics inhibit neutrophil-mediated human aortic endothelial cell injury in vitro. J. Biol. Chem. 269 (1994), 18535.
  • HEARSE D. J.: Myocardial protection during ischemia and reperfusion. Mol. Cell Biochem. 186 (1998), 177.
  • HUSSAIN S. & Au S. F.: Manganese scavenges superoxide and hydroxyl radicals. An in vitro study in rats. Neurosci. Lett. 261 (1999), 21.
  • KASTEN T. P, SETTLE S. L., MISKO T. R, CURRIE M. G. & NrcxoLs G. A.: Manganese potentiation of nitric oxide-mediated vascular relaxation. Eur. J. Pharmacol. 253 (1994), 35.
  • KILGORE K. S., FRIEDRICHS G. S., JOHNSON C. R. et al.: Protective effects of the SOD-mimetic SC-52608 against ischemia/reperfusion damage in the rabbit isolated heart. J. Mol. Cell Cardiol. 26 (1994), 995.
  • KIRSCHNER R. E. & FANTINI G. A.: Role of iron and oxy-gen-derived free radicals in ischemia-reperfusion injury. J. Am. Coll. Surg. 179 (1994), 103.
  • KLONER R. A., Bow R., MARBAN E. et al.: Medical and cellular implication of stunning, hibernation, and precon-ditioning. An NHLBI workshop. Circulation 97 (1998), 1848.
  • LEFER A. M. & LEFER D. J.: Pharmacology of the endo-thelium in ischemia-reperfusion and circulatory shock. Annu. Rev. Pharmacol. Toxicol. 33 (1993), 71.
  • Li Y., HUANG T. T., CARLSON E. J. et al.: Dilated cardio-myopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nat. Genet. 11 (1995), 376.
  • MACKENZIE A. & MARTIN W: Loss of endothelium-de-rived nitric oxide in rabbit aorta by oxidant stress. Restora-tion by superoxide dismutase mimetics. Br. J. Pharmacol. 124 (1998), 719.
  • RUMMENY E. J., TORRES C. G., KURDZIEL J. C., NILSEN G., OP DE BEEcx B. & LUNDBY B.: MnDPDP for MR imaging of the liver. Results of an independent image evaluation of the European phase III studies. Acta Radiol. 38 (1997), 638.
  • SECCOMBE J. F. & SCHAFF H. V.: Coronary artery endo-thelial function after myocardial ischemia and reperfusion. Ann. Thorac. Surg. 60 (1995), 778.
  • SHATTocx M. J. & HADDOCK P S.: Oxidant stress and the heart. Modulation of ion transport mechanisms during ischaemia and reperfusion. In: Immunopharmacology of free radical species, p. 65. Edited by D. Black & P G. Win-yard. Academic Press Ltd., London 1995.
  • TOFT K. G., HUSTVEDT S. 0., GRANT D. et al.: Metabolism and pharmacokinetics of MnDPDP in man. Acta Radiol. 38 (1997), 677.
  • WALLACE K. B.: Free-radical-mediated chemical cardio-myopathies. In: Free radical toxicology, p. 205. Edited by K. B. Wallace. Taylor & Francis Ltd., London 1997.
  • WANG P, CHEN H., QIN H. et al.: Overexpression of human copper, zinc-superoxide dismutase (SOD1) prevents post- ischemic injury. Proc. Natl. Acad. Sci. USA 95 (1998), 4560.
  • WEISS R. H., FRETLAND D. J., BARON D. A., RYAN U. S. & RILEY D. P.: Manganese-based superoxide dismutase mi-metics inhibit neutrophil infiltration in vivo. J. Biol. Chem. 271 (1996), 26149.
  • ZWEIER J. L., FLAHERTY J. T. & WEISFELDT M. L.: Direct measurement of free radical generation following reper-fusion of ischemic myocardium. Proc. Natl. Acad. Sci. USA 84 (1987), 1404.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.