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ORIGINAL ARTICLES: GYNECOLOGICAL CANCERS

Radiotherapy-induced vaginal fibrosis in cervical cancer survivors

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Pages 661-666 | Received 23 Oct 2016, Accepted 18 Dec 2016, Published online: 13 Jan 2017

References

  • Bergmark K, Avall-Lundqvist E, Dickman PW, et al. Vaginal changes and sexuality in women with a history of cervical cancer. N Engl J Med. 1999;340:1383–1389.
  • Vale CTJ, Stewart LA. Reducing uncertainties about the effects of chemoradiotherapy for cervical cancer: a systematic review and meta-analysis of individual patient data from 18 randomized trials. J Clin Oncol. 2008;26:5802–5812.
  • Andreyev HJ, Wotherspoon A, Denham JW, et al. Pelvic radiation disease: new understanding and new solutions for a new disease in the era of cancer survivorship. Scand J Gastroenterol. 2011;46:389–397.
  • Blomgren B, Falconer C, Roomans G, et al. A novel method for visualisation of elastic fibres – suiteble for image analysis and morphometry. Image Anal Stereol. 2001;20:522–526.
  • Danielsson BR, Skold AC, Johansson A, et al. Teratogenicity by the hERG potassium channel blocking drug almokalant: use of hypoxia marker gives evidence for a hypoxia-related mechanism mediated via embryonic arrhythmia. Toxicol Appl Pharmacol. 2003;193:168–176.
  • Gundersen B. Context-dependent plasticity in a sensory circuit. Nat Neurosci. 2013; 16:1366.
  • Rustin MH, Papadaki L, Rode J, et al. Elastic fibres in patients with systemic sclerosis. A morphological study. Virchows Arch a Pathol Anat Histopathol. 1989;416:115–120.
  • Weedon D, Rubin AI, Strutton G. Weedon's Skin Pathology. 3th ed. London: Churchill Livingstone; 2010.
  • Denham JW, Hauer-Jensen M. The radiotherapeutic injury-a complex 'wound'. Radiother Oncol. 2002;63:129–145.
  • Delanian S, Lefaix JL. Current management for late normal tissue injury: radiation-induced fibrosis and necrosis. Semin Radiat Oncol. 2007;17:99–107.
  • Abitbol MM, Davenport JH. Sexual dysfunction after therapy for cervical carcinoma. Am J Obstet Gynecol. 1974;119:181–189.
  • Abitbol MM, Davenport JH. The irradiated vagina. Obstet Gynecol. 1974;44:249–256.
  • Shield PW. Chronic radiation effects: a correlative study of smears and biopsies from the cervix and vagina. Diagn Cytopathol. 1995;13:107–119.
  • Kirchheiner K, Fidarova E, Nout RA, et al. Radiation-induced morphological changes in the vagina. Strahlenther Onkol. 2012;188:1010–1017.
  • Pitkin RM, Bradbury JT. The effect of topical estrogen on irradiated vaginal epithelium. Am J Obstet Gynecol. 1965;92:175–182.
  • Bentzen SM. Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology. Nat Rev Cancer. 2006;6:702–713.
  • Heimer GM, Englund DE. Effects of vaginally-administered oestriol on post-menopausal urogenital disorders: a cytohormonal study. Maturitas. 1992;14:171–179.
  • Gondi V, Bentzen SM, Sklenar KL, et al. Severe late toxicities following concomitant chemoradiotherapy compared to radiotherapy alone in cervical cancer: an inter-era analysis. Int J Radiat Oncol Biol Phys. 2012;84:973–982.

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