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Letters to the Editor

High accumulated doses to the inferior rectum are associated with late gastro-intestinal toxicity in a case-control study of prostate cancer patients treated with radiotherapy

, , , , , , , , & show all
Pages 1543-1546 | Received 02 Apr 2019, Accepted 29 May 2019, Published online: 31 Jul 2019

References

  • Beckendorf V, Guerif S, Le Prisé E, et al. 70 Gy versus 80 Gy in localized prostate cancer: 5-year results of GETUG 06 randomized trial. Int J Radiat Oncol Biol Phys. 2011;80:1056–1063.
  • Heemsbergen WD, Al-Mamgani A, Slot A, et al. Long-term results of the Dutch randomized prostate cancer trial: impact of dose-escalation on local, biochemical, clinical failure, and survival. Radiother Oncol. 2014;110:104–109.
  • Raziee H, Moraes FY, Murgic J, et al. Improved outcomes with dose escalation in localized prostate cancer treated with precision image-guided radiotherapy. Radiother Oncol. 2017;123:459–465.
  • Michalski JM, Gay H, Jackson A, et al. Radiation dose-volume effects in radiation-induced rectal injury. Int J Radiat Oncol Biol Phys. 2010;76:S123–S129.
  • Andreyev H. Gastrointestinal problems after pelvic radiotherapy: the past, the present and the future. Clin Oncol. 2007;19:790–799.
  • Petersen SE, Bentzen L, Emmertsen KJ, et al. Development and validation of a scoring system for late anorectal side-effects in patients treated with radiotherapy for prostate cancer. Radiother Oncol. 2014;111:94–99.
  • Fiorino C, Fellin G, Rancati T, et al. Clinical and dosimetric predictors of late rectal syndrome after 3D-CRT for localized prostate cancer: preliminary results of a multicenter prospective study. Int J Radiat Oncol Biol Phys. 2008;70:1130–1137.
  • Liu M, Moiseenko V, Agranovich A, et al. Normal Tissue Complication Probability (NTCP) modeling of late rectal bleeding following external beam radiotherapy for prostate cancer: a test of the QUANTEC-recommended NTCP model. Acta Oncol. 2010;49:1040–1044.
  • Buettner F, Gulliford SL, Webb S, et al. Modeling late rectal toxicities based on a parameterized representation of the 3D dose distribution. Phys Med Biol. 2011;56:2103–2118.
  • Jaffray DA, Lindsay PE, Brock KK, et al. Accurate accumulation of dose for improved understanding of radiation effects in normal tissue. Int J Radiat Oncol Biol Phys. 2010;76:S135–S139.
  • Buettner F, Gulliford SL, Webb S, et al. Assessing correlations between the spatial distribution of the dose to the rectal wall and late rectal toxicity after prostate radiotherapy: an analysis of data from the MRC RT01 trial (ISRCTN 47772397). Phys Med Biol. 2009;54:6535–6548.
  • Lee R, Chan EK, Kosztyla R, et al. Dose-distance metric that predicts late rectal bleeding in patients receiving radical prostate external-beam radiotherapy. Phys Med Biol. 2012;57:8297–82307.
  • Wortel RC, Witte MG, van der Heide UA, et al. Dose-surface maps identifying local dose-effects for acute gastrointestinal toxicity after radiotherapy for prostate cancer. Radiother Oncol. 2015;117:515–520.
  • Casares-Magaz O, Muren LP, Moiseenko V, et al. Spatial rectal dose/volume metrics predict patient-reported gastro-intestinal symptoms after radiotherapy for prostate cancer. Acta Oncol. 2017;56:1507–1513.
  • Shelley LEA, Scaife JE, Romanchikova M, et al. Delivered dose can be a better predictor of rectal toxicity than planned dose in prostate radiotherapy. Radiother Oncol. 2017;123:466–471.
  • Thor M, Apte A, Deasy JO, et al. Statistical simulations to estimate motion-inclusive dose-volume histograms for prediction of rectal morbidity following radiotherapy. Acta Oncol. 2013;52:666–675.
  • Thor M, Bentzen L, Elstrøm UV, et al. Dose/volume-based evaluation of the accuracy of deformable image registration for the rectum and bladder. Acta Oncol. 2013;52:1411–1416.
  • Hysing LB, Ekanger C, Zolnay A, et al. Statistical motion modelling for robust evaluation of clinically delivered accumulated dose distributions after curative radiotherapy of locally advanced prostate cancer. Radiother Oncol. 2018;128:327–335.
  • Lawton CA, Won M, Pilepich MV, et al. Long-term treatment sequelae following external beam irradiation for adenocarcinoma of the prostate: analysis of RTOG studies 7506 and 7706. Int J Radiat Oncol Biol Phys. 1991;21:935–939.
  • Pollack A, Hanlon AL, Horwitz EM, et al. Dosimetry and preliminary acute toxicity in the first 100 men treated for prostate cancer on a randomized hypofractionation dose escalation trial. Int J Radiat Oncol Biol Phys. 2006;64:518–526.
  • Casares-Magaz O, Thor M, Muren LP, et al. The need for dose re-calculation on cone-beam CTs in dose-response studies of pelvic normal tissues (abstr). Radiother Oncol. 2015;115:S508.
  • Sharma M, Weiss E, Siebers JV. Dose deformation-invariance in adaptive prostate radiation therapy: implication for treatment simulations. Radiother Oncol. 2012;105:207–213.
  • Casares-Magaz O, Moiseenko V, Hopper A, et al. Associations between volume changes and spatial dose metrics for the urinary bladder during local versus pelvic irradiation for prostate cancer. Acta Oncol. 2017;56:884–890.
  • Casares-Magaz O, Muren LP, Pettersson N, et al. A case-control study using motion-inclusive spatial dose-volume metrics to account for genito-urinary toxicity following high-precision radiotherapy for prostate cancer. Phys Med Biol. 2018;7:65–69.
  • Tucker SL, Zhang M, Dong L, et al. Cluster model analysis of late rectal bleeding after IMRT of prostate cancer: a case-control study. Int J Radiat Oncol Biol Phys. 2006;64:1255–1264.
  • Bentzen SM, Dörr W, Gahbauer R, et al. Bioeffect modeling and equieffective dose concepts in radiation oncology-terminology, quantities and units. Radiother Oncol. 2012;105:266–268.
  • Brenner DJ. Fractionation and late rectal toxicity. Int J Radiat Oncol Biol Phys. 2004;60:1013–1015.
  • Chen C, Witte M, Heemsbergen WD, et al. Multiple comparisons permutation test for image based data mining in radiotherapy. Radiat Oncol. 2013;8:293.
  • Heemsbergen WD, Hoogeman MS, Hart GAM, et al. Gastrointestinal toxicity and its relation to dose distributions in the anorectal region of prostate cancer patients treated with radiotherapy. Int J Radiat Oncol Biol Phys. 2005;61:1011–1018.
  • Buettner F, Gulliford SL, Webb S, et al. The dose-response of the anal sphincter region-an analysis of data from the MRC RT01 trial. Radiother Oncol. 2012;103:347–352.
  • Stenmark MH, Conlon ASC, Johnson S, et al. Dose to the inferior rectum is strongly associated with patient reported bowel quality of life after radiation therapy for prostate cancer. Radiother Oncol. 2014;110:291–297.
  • Vanneste BGL, Buettner F, Pinkawa M, et al. Ano-rectal wall dose-surface maps localize the dosimetric benefit of hydrogel rectum spacers in prostate cancer radiotherapy. Clin Transl Radiat Oncol. 2019;14:17–24.

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