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Polypharmacy

A systematic literature review comparing methods for the measurement of patient persistence and adherence

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Pages 1613-1625 | Received 05 Apr 2018, Accepted 15 May 2018, Published online: 04 Jun 2018

References

  • Deshpande S, Quek RG, Forbes CA, et al. A systematic review to assess the adherence and persistence with statins. Curr Med Res Opin 2017;33:769-78
  • Brown MT, Bussell JK. Medication adherence: WHO cares? Mayo Clin Proc 2011;86:304-14
  • Webster R, Rodgers A. Polypill treatments for cardiovascular diseases. Expert Opin Drug Deliv 2016;13:1-6
  • Heads of Medicines Agencies, European Medicines Agency. Guideline on good pharmacovigilance practices (GVP). Module VI – management and reporting of adverse reactions to medicinal products (Rev 1). EMA/873138/2011 Rev 1*. London: European Medicines Agency, 2014. Available at: http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2014/09/WC500172402.pdf [Last accessed 7 February 2017]
  • Higgins JPT, Green S, eds. Cochrane handbook for systematic reviews of interventions. Version 5.1.0. The Cochrane Collaboration, 2011. Available at: http://handbook.cochrane.org/[Last accessed 2 February 2017]
  • Centre for Reviews and Dissemination. Systematic Reviews: CRD’s guidance for undertaking reviews in health care. York: University of York, 2009. Available at: http://www.york.ac.uk/inst/crd/SysRev/!SSL!/WebHelp/SysRev3.htm [Last accessed 2 February 2017]
  • Downs SH, Black N. The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions. J Epidemiol Community Health 1998;52:377-84
  • Brouwers M, Kho ME, Browman GP, et al. AGREE II: advancing guideline development, reporting and evaluation in healthcare. Can Med Assoc J 2010;182:E839-42
  • Whiting P, Savovic J, Higgins JP, et al. ROBIS: a new tool to assess risk of bias in systematic reviews was developed. J Clin Epidemiol 2016;69:225-34
  • Moher D, Liberati A, Tetzlaff J, et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ 2009;339:b2535
  • Daly MW, Seaton T, Moore N, et al. Medication adherence in Medicaid patients with dyslipidemia. Pharmacotherapy 2010;30:419e
  • Dunbar-Jacob J, Sereika SM, Houze M, et al. Accuracy of measures of medication adherence in a cholesterol-lowering regimen. West J Nurs Res 2012;34:578-97
  • Kruse W, Nikolaus T, Rampmaier J, et al. Actual versus prescribed timing of lovastatin doses assessed by electronic compliance monitoring. Eur J Clin Pharmacol 1993;45:211-15
  • Ladova K, Matoulkova P, Zadak Z, et al. Self-reported adherence by MARS-CZ reflects LDL cholesterol goal achievement among statin users: validation study in the Czech Republic. J Eval Clin Pract 2014;20:671-7
  • Schwed A, Fallab CL, Burnier M, et al. Electronic monitoring of compliance to lipid-lowering therapy in clinical practice. J Clin Pharmacol 1999;39:402-9
  • Cheng CWR, Woo KS, Chan JCN, et al. Assessing adherence to statin therapy using patient report, pill count, and an electronic monitoring device. Am J Health Syst Pharm 2005;62:411-15
  • Lee JK, Grace KA, Foster TG, et al. How should we measure medication adherence in clinical trials and practice? Ther Clin Risk Manag 2007;3:685-90
  • Nori AY, Ali MSAK, Ibrahim B, et al. Modifying the Morisky medication adherence scale by adapting two items from the brief medication questionnaire to fit assessing the overall adherence to polypharmacy regimen of cardiac patients. Glob Heart 2014;9(1 Suppl 1):e313
  • Baruel Okumura PC, Okumura LM, Reis WC, et al. Comparing medication adherence tools scores and number of controlled diseases among low literacy patients discharged from a Brazilian cardiology ward. Int J Clin Pharm 2016;38:1362-6
  • Shalansky SJ, Levy AR, Ignaszewski AP. Self-reported Morisky score for identifying nonadherence with cardiovascular medications. Ann Pharmacother 2004;38:1363-8
  • Kripalani S, Risser J, Gatti ME, Jacobson TA. Development and evaluation of the Adherence to Refills and Medications Scale (ARMS) among low-literacy patients with chronic disease. Value Health 2009;12:118-23
  • Zeller A, Ramseier E, Teagtmeyer A, Battegay E. Patients’ self-reported adherence to cardiovascular medication using electronic monitors as comparators. Hypertens Res 2008;31:2037-43
  • Vink NM, Klungel OH, Stolk RP, Denig P. Comparison of various measures for assessing medication refill adherence using prescription data. Pharmacoepidemiol Drug Saf 2009;18:159-65
  • Karter AJ, Parker MM, Moffet HH, et al. New prescription medication gaps: a comprehensive measure of adherence to new prescriptions. Health Serv Res 2009;44:1640-61
  • LaFleur J, McAdam-Marx C, White GL, et al. Comparing medication adherence methods in lipid-modifying therapy. J Pharm Technol 2012;28:58-67
  • Raebel MA, Carroll NM, Ellis JL, et al. Importance of including early nonadherence in estimations of medication adherence. Ann Pharmacother 2011;45:1053-60
  • Clifford S, Perez-Nieves M, Skalicky AM, et al. A systematic literature review of methodologies used to assess medication adherence in patients with diabetes. Curr Med Res Opin 2014;30:1071-85
  • Stolpe S, Kroes MA, Webb N, Wisniewski T. A systematic review of insulin adherence measures in patients with diabetes. J Manag Care Spec Pharm 2016;22:1224-46
  • Perez-Escamilla B, Franco-Trigo L, Moullin JC, et al. Identification of validated questionnaires to measure adherence to pharmacological antihypertensive treatments. Patient Prefer Adherence 2015;9:569-78
  • Ma Q, Kao C, Miles G, Chen G. Measurement of adherence to anti-hypertensive drugs in Asia. Value Health 2016;19:A868
  • Scheiman-Elazary A, Shourt C, Hay MC, Furst D. A meta-analysis and systematic literature review: effect of the method used to measure adherence in rheumatoid arthritis on its rate, and evaluation of associated factors. Arthritis Rheum 2013;65:S76-S7
  • ReHOT Investigators; Krieger EM, Drager LF, Giorgi DM, et al. Resistant hypertension optimal treatment trial: a randomized controlled trial. [Erratum appears in Clin Cardiol 2014;37:388]. Clin Cardiol 2014;37:1-6
  • Hutchins DS, Zeber JE, Roberts CS, et al. Initial medication adherence – review and recommendations for good practices in outcomes research: an ISPOR Medication Adherence and Persistence Special Interest Group report. Value Health 2015;18:690-9
  • Gwadry-Sridhar FH, Manias E, Zhang Y, et al. A framework for planning and critiquing medication compliance and persistence research using prospective study designs. Clin Ther 2009;31:421-35
  • National Institute for Health and Care Excellence (NICE). Medicines optimisation. Quality standard [QS120]. London: National Institute for Health and Care Excellence, 2016. Available at: https://www.nice.org.uk/guidance/qs120 [Last accessed 28 March 2017]
  • National Institute for Health and Care Excellence (NICE). Medicines adherence: involving patients in decisions about prescribed medicines and supporting adherence. Clinical guideline [CG76]. London: National Institute for Health and Care Excellence, 2009. Available at: https://www.nice.org.uk/guidance/cg76 [Last accessed 28 March 2017]
  • Nau DP. Proportion of days covered (PDC) as a preferred method of measuring medication adherence. Alexandria, VA: Pharmacy Quality Alliance, 2015 Available at: http://pqaalliance.org/resources/adherence.asp [Last accessed 2 February 2017]
  • University of Michigan Health System. Secondary prevention of ischemic heart disease and stroke in adults. Ann Arbor, MI: University of Michigan Health System, 2009. Available at: https://www.guideline.gov/summaries/summary/48221
  • Nordstrom BL, Simeone JC, Zhao Z, et al. Adherence and persistence with prasugrel following acute coronary syndrome with percutaneous coronary intervention. Am J Cardiovasc Drugs 2013;13:263-71
  • American Association for Thoracic Surgery, American College of Cardiology Foundation, American College of Physicians, American Heart Association, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, et al. 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease. 2012. Available at: https://www.guideline.gov/summaries/summary/39380/. [Last accessed 21 September 2017]
  • Piepoli MF, Hoes AW, Agewall S, et al. 2016 European guidelines on cardiovascular disease prevention in clinical practice: the Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts). Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR). Eur Heart J 2016;37:2315-81
  • Catapano AL, Graham I, De Backer G, et al. 2016 ESC/EAS guidelines for the management of dyslipidaemias. Eur Heart J 2016;37:2999-3058
  • Medicines and Healthcare products Regulatory Agency (MHRA). Welcome to The Clinical Practice Research Datalink. London: MHRA, 2017. Available at: https://www.cprd.com/Home/ [Last accessed 18 December 2017]
  • Kela. Reimbursements of medicine expenses: number of recipients and prescription data (Kelasto statistical database). Finland: Kela. Available at: http://raportit.kela.fi/ibi_apps/WFServlet?IBIF_ex=NIT137AL&YKIELI=E [Last accessed 18 December 2017]
  • Folkehelseinstituttet (Norwegian Institute of Public Health). Welcome to the Norwegian Prescription Database (NorPD). Oslo, Norway: Folkehelseinstituttet, 2017. Available at: http://www.norpd.no/[Last accessed 18 December 2017]
  • Sundhedsdata-Styrelsen (Danish Health Data Authority). Medstat.dk. Copenhagen, Denmark: Sundhedsdata-Styrelsen. Available at: http://www.medstat.dk/en [Last accessed 18 December 2017]
  • Shi L, Liu J, Koleva Y, et al. Concordance of adherence measurement using self-reported adherence questionnaires and medication monitoring devices. PharmacoEcon 2010;28:1097-107
  • Shea S, Misra D, Ehrlich MH, et al. Correlates of nonadherence to hypertension treatment in an inner-city minority population. Am J Public Health 1992;82:1607-12
  • Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self-reported measure of medication adherence. Med Care 1986;24:67-74
  • Morisky DE, Ang A, Krousel-Wood M, Ward H. Predictive validity of a medication adherence measure for hypertension control. J Clin Hypertens 2008;10:348-54
  • Cea-Calvo L, Carmona L, Calvo-Alén J. The challenge of assessing adherence to subcutaneous biological drugs in immune-mediated inflammatory diseases. Letter to the editor regarding Michetti P, Weinman J, Mrowietz U, et al. Adv Ther (2017);34:91-108. Adv Ther 2017;34:2173-6
  • Pednekar P, Malmenas M, Ágh T, et al.; on behalf of the Leadership Members of the Multiple Medication Adherence Measurement Working Group of the ISPOR Medication Adherence and Persistence Special Interest Group. Measuring multiple medication adherence – which measure when? Value & Outcomes Spotlight 2017;3:17-20
  • Helmy R, Zullig LL, Dunbar-Jacob J, Hughes DA, Vrijens B, Wilson IB, et al. ESPACOMP Medication Adherence Reporting Guidelines (EMERGE): a reactive-Delphi study protocol. BMJ OPEN 2017;7:e013496
  • Jimmy B, Jose J. Patient medication adherence: measures in daily practice. Oman Med J 2011;26:155-9
  • Malo S, Aguilar-Palacio I, Feja C, Lallana MJ, Rabanaque MJ, Armesto J, et al. Different approaches to the assessment of adherence and persistence with cardiovascular-disease preventive medications. Curr Med Res Opin 2017;33:1329-36
  • Hughes D, Cowell W, Koncz T, Cramer J. International Society for Pharmacoeconomics & Outcomes Research Economics of Medication Compliance Working Group. Methods for integrating medication compliance and persistence in pharmacoeconomic evaluations. Value Health 2007;10:498-509

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