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Pain Medicine

Medical cannabis and its efficacy/effectiveness on the management of osteoarthritis pain and function

ORCID Icon, , &
Pages 1195-1202 | Received 06 Feb 2024, Accepted 31 May 2024, Published online: 10 Jun 2024

References

  • Sen R, Hurley JA. Osteoarthritis. Treasure Island (FL): StatPearls; 2022.
  • Gusho CA, Court T. Cannabidiol: a brief review of its therapeutic and pharmacologic efficacy in the management of joint disease. Cureus. 2020;12(3):e7375. doi:10.7759/cureus.7375.
  • Wang A, Lo A, Ubhi K, et al. Small and transient effect of cannabis oil for osteoarthritis-related joint pain: a case report. Can J Hosp Pharm. 2021;74(2):156–158.
  • Ivers N, Dhalla IA, Allan GM. Opioids for osteoarthritis pain: benefits and risks. Can Fam Physician. 2012;58(12):e708.
  • Welsch P, Petzke F, Klose P, et al. Opioids for chronic osteoarthritis pain: an updated systematic review and meta-analysis of efficacy, tolerability and safety in randomized placebo-controlled studies of at least 4 weeks double-blind duration. Eur J Pain. 2020;24(4):685–703.
  • Thorlund JB, Turkiewicz A, Prieto-Alhambra D, et al. Opioid use in knee or hip osteoarthritis: a region-wide population-based cohort study. Osteoarthritis Cartilage. 2019;27(6):871–877. doi:10.1016/j.joca.2019.01.005.
  • Deckey DG, Lara NJ, Gulbrandsen MT, et al. Prevalence of Cannabinoid use in patients with hip and knee osteoarthritis. J Am Acad Orthop Surg Glob Res Rev. 2021;5(2):e20.00172. doi:10.5435/JAAOSGlobal-D-20-00172.
  • Renslo B, Greis A. Medical cannabis use reduces opioid prescriptions in patients with chronic osteoarthritis pain. PMR. 2021 2021;13: s170.
  • Hunter D, Oldfield G, Tich N, et al. Synthetic transdermal cannabidiol for the treatment of knee pain due to osteoarthritis. Osteoarthritis Cartilage. 2018;26: S26. doi:10.1016/j.joca.2018.02.067.
  • Bryk M, Starowicz K. Cannabinoid-based therapy as a future for joint degeneration. Focus on the role of CB(2) receptor in the arthritis progression and pain: an updated review. Pharmacol Rep. 2021;73(3):681–699. doi:10.1007/s43440-021-00270-y.
  • Gago-Rodrigues I, Águas F, Nascimento J, et al. Usage of medical cannabis in elderly patients with chronic pain associated diseases. Med Cannabis Cannabinoids. 2020;3(2):129.
  • The Health Effects of Cannabis and Cannabinoids. The current state of evidence and recommendations for research. The national academies collection: reports funded by National Institutes of Health. Washington (DC); 2017.
  • Khurshid H, Qureshi IA, Jahan N, et al. A systematic review of fibromyalgia and recent advancements in treatment: is medicinal Cannabis a new hope? Cureus. 2021;13(8):e17332. doi:10.7759/cureus.17332.
  • Riva JJ, Malik KM, Burnie SJ, et al. What is your research question? An introduction to the PICOT format for clinicians. J Can Chiropr Assoc. 2012;56(3):167–171.
  • Frane N, Stapleton E, Iturriaga C, et al. Cannabidiol as a treatment for arthritis and joint pain: an exploratory cross-sectional study. J Cannabis Res. 2022;4(1):47. doi:10.1186/s42238-022-00154-9.
  • Heineman JT, Forster GL, Stephens KL, et al. A randomized controlled trial of topical cannabidiol for the treatment of thumb basal joint arthritis. J Hand Surg Am. 2022;47(7):611–620.
  • Fader L, Scharf Z, DeGeorge BR. Jr. Assessment of medical cannabis in patients with osteoarthritis of the thumb basal joint. J Hand Surg Am. 2023;48(3):257–262.e1. doi:10.1016/j.jhsa.2021.10.018.
  • Habib G, Khazin F, Artul S. The effect of medical cannabis on pain level and quality of sleep among rheumatology clinic outpatients. Pain Res Manag. 2021;2021:1756588. doi:10.1155/2021/1756588.
  • Vela J, Kjær Petersen K, Dreyer L, et al. The effect of Cannabidiol on quantitative sensory testing parameters in patients with hand osteoarthritis and psoriatic arthritis: a randomized double-blind placebo-controlled trial. Ann Rheum Dis. 2022;81(Suppl 1):821–822. doi:10.1136/annrheumdis-2022-eular.1101.
  • Frane N, Stapleton E, Ganz M, et al. An exploratory cross-sectional analysis of cannabidiol use for arthritic joint pain. Med Cannabis Cannabinoids. 2021;4(2):129–130.
  • Vela J, Kristensen S, Dreyer L, et al. Cannabidiol treatment in hand osteoarthritis and psoriatic arthritis-a randomized, double-blind placebo-controlled trial. Arthritis Rheumatol. 2021;73:3056–3057.
  • Bains S, Mukhdomi T. Medicinal Cannabis for treatment of chronic pain. Treasure Island (FL): StatPearls; 2023.
  • Vulfsons S, Minerbi A, Sahar T. Cannabis and pain treatment-a review of the clinical utility and a practical approach in light of uncertainty. Rambam Maimonides Med J. 2020;11(1):e0002. doi:10.5041/RMMJ.10385.
  • Gabrielsson L, Mattsson S, Fowler CJ. Palmitoylethanolamide for the treatment of pain: pharmacokinetics, safety and efficacy. Br J Clin Pharmacol. 2016;82(4):932–942. doi:10.1111/bcp.13020.
  • Steels E, Venkatesh R, Steels E, et al. A double-blind randomized placebo controlled study assessing safety, tolerability and efficacy of palmitoylethanolamide for symptoms of knee osteoarthritis. Inflammopharmacology. 2019;27(3):475–485. doi:10.1007/s10787-019-00582-9.
  • Marini I, Bartolucci ML, Bortolotti F, et al. Palmitoylethanolamide versus a nonsteroidal anti-inflammatory drug in the treatment of temporomandibular joint inflammatory pain. J Orofac Pain. 2012;26(2):99–104.
  • Pramhas S, Thalhammer T, Terner S, et al. Oral cannabidiol (CBD) as add-on to paracetamol for painful chronic osteoarthritis of the knee: a randomized, double-blind, placebo-controlled clinical trial. Lancet Reg Health Eur. 2023;35:100777.

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