Adiponectin mitigates the severity of arthritis in mice with collagen‐induced arthritis

References

• Choy E. H., Panayi G. S. Cytokine pathways and joint inflammation in rheumatoid arthritis. N Engl J Med 2001; 344: 907–16
   PubMed Web of Science ®Google Scholar
• Hochberg M. C., Silman A. J., Smolen J. S., Weinblatt M. E., Weisman M. H. Rheumatology. Mosby, London
   Google Scholar
• Fantuzzi G. Adipose tissue, adipokines, and inflammation. J Allergy Clin Immunol 2005; 115: 911–19
   PubMed Web of Science ®Google Scholar
• Wang Y., Lam K. S., Chan L., Chan K. W., Lam J. B., Lam M. C., et al. Post‐translational modifications of the four conserved lysine residues within the collagenous domain of adiponectin are required for the formation of its high molecular weight oligomeric complex. J Biol Chem 2006; 281: 16391–400
   PubMed Web of Science ®Google Scholar
• Yokota T., Oritani K., Takahashi I., Ishikawa J., Matsuyama A., Ouchi N., et al. Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood 2000; 96: 1723–32
   PubMed Web of Science ®Google Scholar
• Ouchi N., Kihara S., Arita Y., Okamoto Y., Maeda K., Kuriyama H., et al. Adiponectin, an adipocyte‐derived plasma protein, inhibits endothelial NF‐kappaB signaling through a cAMP‐dependent pathway. Circulation 2000; 102: 1296–301
   PubMed Web of Science ®Google Scholar
• Kumada M., Kihara S., Ouchi N., Kobayashi H., Okamoto Y., Ohashi K., et al. Adiponectin specifically increased tissue inhibitor of metalloproteinase‐1 through interleukin‐10 expression in human macrophages. Circulation 2004; 109: 2046–9
   PubMed Web of Science ®Google Scholar
• Wolf A. M., Wolf D., Rumpold H., Enrich B., Tilg H. Adiponectin induces the anti‐inflammatory cytokines IL‐10 and IL‐1RA in human leukocytes. Biochem Biophys Res Commun 2004; 323: 630–5
   PubMed Web of Science ®Google Scholar
• Wulster‐Radcliffe M. C., Ajuwon K. M., Wang J., Christian J. A., Spurlock M. E. Adiponectin differentially regulates cytokines in porcine macrophages. Biochem Biophys Res Commun 2004; 316: 924–9
   PubMed Web of Science ®Google Scholar
• Kawanami D., Maemura K., Takeda N., Harada T., Nojiri T., Imai Y., et al. Direct reciprocal effects of resistin and adiponectin on vascular endothelial cells: a new insight into adipocytokine–endothelial cell interactions. Biochem Biophys Res Commun 2004; 314: 415–19
   PubMed Web of Science ®Google Scholar
• Luo X. H., Guo L. J., Yuan L. Q., Xie H., Zhou H. D., Wu X. P., et al. Adiponectin stimulates human osteoblasts proliferation and differentiation via the MAPK signaling pathway. Exp Cell Res 2005; 309: 99–109
   PubMed Web of Science ®Google Scholar
• Lappas M., Permezel M., Rice G. E. Leptin and adiponectin stimulate the release of proinflammatory cytokines and prostaglandins from human placenta and maternal adipose tissue via nuclear factor‐kappaB, peroxisomal proliferator‐activated receptor‐gamma and extracellularly regulated kinase 1/2. Endocrinology 2005; 146: 3334–42
   PubMed Web of Science ®Google Scholar
• Schaffler A., Ehling A., Neumann E., Herfarth H., Tarner I., Scholmerich J., et al. Adipocytokines in synovial fluid. J Am Med Assoc 2003; 290: 1709–10
   PubMed Web of Science ®Google Scholar
• Stefan N., Haring H. U., Stumvoll M. Regulation of synovial adipocytokines. J Am Med Assoc 2004; 291: 694–5
   Google Scholar
• Otero M., Lago R., Gomez R., Lago F., Dieguez C., Gomez‐Reino J. J., et al. Changes in plasma levels of fat‐derived hormones adiponectin, leptin, resistin and visfatin in patients with rheumatoid arthritis. Ann Rheum Dis 2006; 65: 1198–201
   PubMed Web of Science ®Google Scholar
• Lee J. S., Cho M. L., Jhun J. Y., Min S. Y., Ju J. H., Yoon C. H., et al. Antigen‐specific expansion of TCR Vbeta3+ CD4+ T cells in the early stage of collagen‐induced arthritis and its arthritogenic role in DBA/1J mice. J Clin Immunol 2006; 26: 204–12
   PubMedGoogle Scholar
• Cho M. L., Kang J. W., Moon Y. M., Nam H. J., Jhun J. Y., Heo S. B., et al. STAT3 and NF‐kappaB signal pathway is required for IL‐23‐mediated IL‐17 production in spontaneous arthritis animal model IL‐1 receptor antagonist‐deficient mice. J Immunol 2006; 176: 5652–61
   PubMed Web of Science ®Google Scholar
• Manigrasso M. R., Ferroni P., Santilli F., Taraborelli T., Guagnano M. T., Michetti N., et al. Association between circulating adiponectin and interleukin‐10 levels in android obesity: effects of weight loss. J Clin Endocrinol Metab 2005; 90: 5876–9
   PubMed Web of Science ®Google Scholar
• Berg A. H., Scherer P. E. Adipose tissue, inflammation, and cardiovascular disease. Circ Res 2005; 96: 939–49
   PubMed Web of Science ®Google Scholar
• Sennello J. A., Fayad R., Morris A. M., Eckel R. H., Asilmaz E., Montez J., et al. Regulation of T cell‐mediated hepatic inflammation by adiponectin and leptin. Endocrinology 2005; 146: 2157–64
   PubMedGoogle Scholar
• Salmenniemi U., Ruotsalainen E., Pihlajamaki J., Vauhkonen I., Kainulainen S., Punnonen K., et al. Multiple abnormalities in glucose and energy metabolism and coordinated changes in levels of adiponectin, cytokines, and adhesion molecules in subjects with metabolic syndrome. Circulation 2004; 110: 3842–8
   PubMed Web of Science ®Google Scholar
• Barnes P. J., Karin M. Nuclear factor‐kappaB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 1997; 336: 1066–71
   PubMed Web of Science ®Google Scholar
• Ajuwon K. M., Spurlock M. E. Adiponectin inhibits LPS‐induced NF‐kappaB activation and IL‐6 production and increases PPARgamma2 expression in adipocytes. Am J Physiol Regul Integr Comp Physiol 2005; 288: R1220–5
   PubMed Web of Science ®Google Scholar
• Ehling A., Schaffler A., Herfarth H., Tarner I. H., Anders S., Distler O., et al. The potential of adiponectin in driving arthritis. J Immunol 2006; 176: 4468–78
   PubMed Web of Science ®Google Scholar
• Rovin B. H., Song H., Hebert L. A., Nadasdy T., Nadasdy G., Birmingham D. J., et al. Plasma, urine, and renal expression of adiponectin in human systemic lupus erythematosus. Kidney Int 2005; 68: 1825–33
   PubMed Web of Science ®Google Scholar
• Toussirot E., Streit G., Nguyen N. U., Dumoulin G., Le Huédé G., Saas P., et al. Adipose tissue, serum adipokines, and ghrelin in patients with ankylosing spondylitis. Metabolism 2007; 56: 1383–9
   PubMed Web of Science ®Google Scholar