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Articles

Pedunculoside attenuates pathological phenotypes of fibroblast-like synoviocytes and protects against collagen-induced arthritis

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Pages 383-392 | Accepted 25 Mar 2019, Published online: 29 Jul 2019

References

  • Lahoti TS, Hughes JM, Kusnadi A, John K, Zhu B, Murray IA, et al. Aryl hydrocarbon receptor antagonism attenuates growth factor expression, proliferation, and migration in fibroblast-like synoviocytes from patients with rheumatoid arthritis. J Pharmacol Exp Ther 2014;348:236–45.
  • Neidhart M, Seemayer CA, Hummel KM, Michel BA, Gay RE, Gay S. Functional characterization of adherent synovial fluid cells in rheumatoid arthritis: destructive potential in vitro and in vivo. Arthritis Rheum 2014;48:1873–80.
  • Noss EH, Brenner MB. The role and therapeutic implications of fibroblast-like synoviocytes in inflammation and cartilage erosion in rheumatoid arthritis. Immunol Rev 2008;223:252–70.
  • Bartok B, Firestein GS. Fibroblast-like synovioctyes: key effector cells in rheumatoid arthritis. Immunol Rev 2011;233:233–55.
  • Mor A, Abramson SB, Pillinger MH. The fibroblast-like synovial cell in rheumatoid arthritis: a key player in inflammation and joint destruction. Clin Immunol 2005;115:118–28.
  • Laragione T, Brenner M, Mello A, Symons M, Gulko PS. The arthritis severity locus Cia5d is a novel genetic regulator of the invasive properties of synovial fibroblasts. Arthritis Rheum 2010;58:2296–306.
  • Tolboom TC, Ah HVM, Nelissen RG, Breedveld FC, Toes RE, Huizinga TW. Invasiveness of fibroblast-like synoviocytes is an individual patient characteristic associated with the rate of joint destruction in patients with rheumatoid arthritis. Arthritis Rheum 2005;52:1999–2002.
  • Scott DL. Biologics-based therapy for the treatment of rheumatoid arthritis. Clin Pharmacol Ther 2012;91:30–43.
  • Seguro PF, Delgado AJ. Non-tumor necrosis factor-based biologic therapies for rheumatoid arthritis: present, future, and insights into pathogenesis. Biologics 2014;8:1–12.
  • Rong Y, Shen Y, Wang J, Zhang Y, Fan Y, Sun Y, et al. [The effects of pedunculoside on the liver injury in mice and the gastrocnemius damage in rat], in Chinese. J Yangzhou Univ 2016;37:24–9.
  • Jahromi MAF, Gupta M, Manickam M, Ray AB, Chansouria JPN. Hypolipidemic activity of pedunculoside, a constituent of Ilex doniana. Pharm Biol 1999;37:37–41.
  • Yan Z, Su M, Pan W, Su W, Wang Y. A simple method for extraction and purification of pedunculoside from the dried barks of Ilex rotunda and its inhibitory effect on pancreatic lipase in vitro. Sep Sci Technol 2017;52:2878–87.
  • Liu C, Shen YJ, Tu QB, Zhao YR, Guo H, Wang J, et al. Pedunculoside, a novel triterpene saponin extracted from Ilex rotunda, ameliorates high-fat diet induced hyperlipidemia in rats. Biomed Pharmacother 2018;101:608–16.
  • Liu C, Zhang W, Yang H, Sun W, Gong X, Zhao J, et al. A water-soluble inclusion complex of pedunculoside with the polymer β-cyclodextrin: a novel anti-inflammation agent with low toxicity. PLoS One 2014;9:e101761.
  • Liu J, Zhang Y. [Study on the effect of the presence of pedunculoside on myocardial ischemia in rats], in Chinese. Smart Healthcare 2017;1:53–5.
  • Qiu H, Li H, Liu Z, Sun S, Ma X, Liu M. [Isolation, culture and identification of fibroblast-like synoviocytes from Collagen-Induced Arthritis (CIA) rats], in Chinese. J Nanjing Normal Univ 2017;40:128–32.
  • Liu M, Zhou X, Zhou L, Liu Z, Yuan J, Cheng J, et al. Carnosic acid inhibits inflammation response and joint destruction on osteoclasts, fibroblast-like synoviocytes, and collagen-induced arthritis rats. J Cell Physiol 2018;233:1–13.
  • Qiu H, Sun S, Ma X, Cui C, Chen G, Liu Z, et al. Jatrorrhizine hydrochloride suppresses proliferation, migration, and secretion of synoviocytes in vitro and ameliorates rat models of rheumatoid arthritis in vivo. Int J Mol Sci 2018;19:1514.
  • Liu Z, Zhou L, Ma X, Sun S, Qiu H, Li H, et al. Inhibitory effects of tubeimoside I on synoviocytes and collagen-induced arthritis in rats. J Cell Physiol 2018;233:8740–53.
  • Liu C, Zhang Y, Kong X, Zhu L, Pang J, Xu Y, et al. Triptolide prevents bone destruction in the collagen-induced arthritis model of rheumatoid arthritis by targeting RANKL/RANK/OPG signal pathway. Evid Based Complement Alternat Med 2013;2013:1–12.
  • Cai X, Zhou H, Wong YF, Xie Y, Liu ZQ, Jiang ZH, et al. Suppression of the onset and progression of collagen-induced arthritis in rats by QFGJS, a preparation from an anti-arthritic Chinese herbal formula. J Ethnopharmacol 2007;110:39–48.
  • Xin W, Huang C, Zhang X, Xin S, Zhou Y, Ma X, et al. Methyl salicylate lactoside inhibits inflammatory response of fibroblast-like synoviocytes and joint destruction in collagen-induced arthritis in mice. Br J Pharmacol 2014;171:3526–38.
  • Holmdahl R, Rubin K, Klareskog L, Larsson E, Wigzell H. Characterization of the antibody response in mice with type II collagen-induced arthritis, using monoclonal anti-type II collagen antibodies. Arthritis Rheum 1986;29:400–10.
  • Terato K, Hasty KA, Reife RA, Cremer MA, Kang AH, Stuart JM. Induction of arthritis with monoclonal antibodies to collagen. J Immunol 1992;148:2103–8.
  • Mcinnes IB, Schett G. Cytokines in the pathogenesis of rheumatoid arthritis. Nat Rev Immunol 2007;7:429–42.
  • Georganas C, Liu H, Perlman H, Hoffmann A, Thimmapaya B, Pope RM. Regulation of IL-6 and IL-8 expression in rheumatoid arthritis synovial fibroblasts: the dominant role for NF-kappa B but not C/EBP beta or c-Jun. J Immunol 2000;165:7199–206.
  • Guo Q, Wang Y, Xu D, Nossent J, Pavlos NJ, Xu J. Rheumatoid arthritis: pathological mechanisms and modern pharmacologic therapies. Bone Res 2018;6:15.
  • Schett G, Steiner CW, Xu Q, Smolen JS, Steiner G. TNFalpha mediates susceptibility to heat-induced apoptosis by protein phosphatase-mediated inhibition of the HSF1/hsp70 stress response. Cell Death Differ 2003;10:1126–36.
  • Hwang D, Kim WU. Rheumatoid arthritis: modelling cytokine signalling networks. Nat Rev Rheumatol 2016;13:5–6.
  • Asami T, Kishida M, Mabuchi T, Kim BT, Ichinose K, Yoshida S. Tacrolimus (FK506) inhibits interleukin-1β-induced angiopoietin-1, Tie-2 receptor, and vascular endothelial growth factor through down-regulation of JNK and p38 pathway in human rheumatoid fibroblast-like synoviocytes. Joint Bone Spine 2012;79:137–43.
  • Inoue T, Hammaker D, Boyle DL, Firestein GS. Regulation of p38 MAPK by MAPK kinases 3 and 6 in fibroblast-like synoviocytes. J Immunol 2005;174:4301–6.
  • Scheinman R. NF-κB and rheumatoid arthritis: will understanding genetic risk lead to a therapeutic reward? For Immunopathol Dis Therap 2013;4:93–110.
  • You C, Zu J, Liu X, Kong P, Song C, Wei R, et al. Synovial fibroblast-targeting liposomes encapsulating an NF-κB-blocking peptide ameliorates zymosan-induced synovial inflammation. J Cell Mol Med 2018;22:2449–57.
  • Zuo J, Yin Q, Wang YW, Li Y, Lu LM, Xiao ZG, et al. Inhibition of NF-κB pathway in fibroblast-like synoviocytes by α-mangostin implicated in protective effects on joints in rats suffering from adjuvant-induced arthritis. Int Immunopharmacol 2018;56:78–89.
  • Gravallese EM. Bone destruction in arthritis. Ann Rheum Dis 2002;61(Suppl 2):ii84–6.
  • Skapenko A, Leipe J, Lipsky PE, Schulze-Koops H. The role of the T cell in autoimmune inflammation. Arthritis Res Ther 2005;7(Suppl 2):S4–14.
  • Ma Y, Pope RM. The role of macrophages in rheumatoid arthritis. Curr Pharm Des 2005;11:569–80.

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