Cluster analysis identifies unmet healthcare needs among patients with rheumatoid arthritis

References

• Alemao E, Joo S, Kawabata H, Al MJ, Allison PD, Rutten-van Molken MP, et al. Effects of achieving target measures in rheumatoid arthritis on functional status, quality of life, and resource utilization: analysis of clinical practice data. Arthritis Care Res (Hoboken) 2016;68:308–17.
   PubMed Web of Science ®Google Scholar
• Curtis JR, Chen L, Greenberg JD, Harrold L, Kilgore ML, Kremer JM, et al. The clinical status and economic savings associated with remission among patients with rheumatoid arthritis: leveraging linked registry and claims data for synergistic insights. Pharmacoepidemiol Drug Saf 2017;26:310–9.
   PubMed Web of Science ®Google Scholar
• Rantalaiho V, Puolakka K, Korpela M, Hannonen P, Mottonen T. Long-term results of the FIN-RACo trial; treatment with a combination of traditional disease-modifying anti-rheumatic drugs is an excellent option in early rheumatoid arthritis. Clin Exp Rheumatol 2012;30:S27–31.
   PubMed Web of Science ®Google Scholar
• Taylor PC, Moore A, Vasilescu R, Alvir J, Tarallo M. A structured literature review of the burden of illness and unmet needs in patients with rheumatoid arthritis: a current perspective. Rheumatol Int 2016;36:685–95.
   PubMed Web of Science ®Google Scholar
• Fautrel B, Alten R, Kirkham B, de la Torre I, Durand F, Barry J, et al. Call for action: how to improve use of patient-reported outcomes to guide clinical decision making in rheumatoid arthritis. Rheumatol Int 2018;38:935–47.
   PubMed Web of Science ®Google Scholar
• An J, Nyarko E, Hamad MA. Prevalence of comorbidities and their associations with health-related quality of life and healthcare expenditures in patients with rheumatoid arthritis. Clin Rheumatol 2019;38:2717–26.
   PubMed Web of Science ®Google Scholar
• Husberg M, Davidson T, Hallert E. Non-medical costs during the first year after diagnosis in two cohorts of patients with early rheumatoid arthritis, enrolled 10 years apart. Clin Rheumatol 2017;36:499–506.
   PubMed Web of Science ®Google Scholar
• Huscher D, Mittendorf T, von Hinuber U, Kotter I, Hoese G, Pfafflin A, et al. Evolution of cost structures in rheumatoid arthritis over the past decade. Ann Rheum Dis 2015;74:738–45.
   PubMed Web of Science ®Google Scholar
• van den Akker-van Marle ME, Chorus AM, Vliet Vlieland TP, van den Hout WB. Cost of rheumatic disorders in the Netherlands. Best Pract Res Clin Rheumatol 2012;26:721–31.
   PubMed Web of Science ®Google Scholar
• Mars NJ, Kerola AM, Kauppi MJ, Pirinen M, Elonheimo O, Sokka-Isler T. Patients with rheumatic diseases share similar patterns of healthcare resource utilization. Scand J Rheumatol 2019;48:300–7.
   PubMed Web of Science ®Google Scholar
• Huscher D, Merkesdal S, Thiele K, Zeidler H, Schneider M, Zink A, et al. Cost of illness in rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis and systemic lupus erythematosus in Germany. Ann Rheum Dis 2006;65:1175–83.
   PubMed Web of Science ®Google Scholar
• Beresniak A, Gossec L, Goupille P, Saraux A, Bamberger M, Bregman B, et al. Direct cost-modeling of rheumatoid arthritis according to disease activity categories in France. J Rheumatol 2011;38:439–45.
   PubMed Web of Science ®Google Scholar
• Jain AK. Data clustering: 50 years beyond K-means. Pattern Recognit Lett 2010;31:651–66.
   Web of Science ®Google Scholar
• Vare P, Nikiphorou E, Hannonen P, Sokka T. Delivering a one-stop, integrated, and patient-centered service for patients with rheumatic diseases. SAGE Open Med 2016;4:2050312116654404.
   Web of Science ®Google Scholar
• England BR, Sayles H, Mikuls TR, Johnson DS, Michaud K. Validation of the rheumatic disease comorbidity index. Arthritis Care Res (Hoboken) 2015;67:865–72.
   PubMed Web of Science ®Google Scholar
• Richette P, Clerson P, Perissin L, Flipo RM, Bardin T. Revisiting comorbidities in gout: a cluster analysis. Ann Rheum Dis 2015;74:142–7.
   PubMed Web of Science ®Google Scholar
• Newcomer SR, Steiner JF, Bayliss EA. Identifying subgroups of complex patients with cluster analysis. Am J Manag Care 2011;17:e324–32.
   PubMed Web of Science ®Google Scholar
• Carpenter L, Nikiphorou E, Kiely PDW, Walsh DA, Young A, Norton S. Secular changes in the progression of clinical markers and patient-reported outcomes in early rheumatoid arthritis. Rheumatology (Oxford) 2020;59:2381–91.
   PubMed Web of Science ®Google Scholar
• Carpenter L, Barnett R, Mahendran P, Nikiphorou E, Gwinnutt J, Verstappen S, et al. Secular changes in functional disability, pain, fatigue and mental well-being in early rheumatoid arthritis. A longitudinal meta-analysis. Semin Arthritis Rheum 2020;50:209–19.
   PubMed Web of Science ®Google Scholar
• Geenen R, Overman CL, Christensen R, Asenlof P, Capela S, Huisinga KL, et al. EULAR recommendations for the health professional’s approach to pain management in inflammatory arthritis and osteoarthritis. Ann Rheum Dis 2018;77:797–807.
   PubMed Web of Science ®Google Scholar
• Gron KL, Ornbjerg LM, Hetland ML, Aslam F, Khan NA, Jacobs JW, et al. The association of fatigue, comorbidity burden, disease activity, disability and gross domestic product in patients with rheumatoid arthritis. Results from 34 countries participating in the Quest-RA program. Clin Exp Rheumatol 2014;32:869–77.
   PubMed Web of Science ®Google Scholar
• Lee YC, Frits ML, Iannaccone CK, Weinblatt ME, Shadick NA, Williams DA, et al. Subgrouping of patients with rheumatoid arthritis based on pain, fatigue, inflammation, and psychosocial factors. Arthritis Rheumatol. 2014;66:2006–14.
   PubMed Web of Science ®Google Scholar
• Ziade N, El Khoury B, Zoghbi M, Merheb G, Abi Karam G, Mroue K, et al. Prevalence and pattern of comorbidities in chronic rheumatic and musculoskeletal diseases: the COMORD study. Sci Rep 2020;10:7683.
   PubMed Web of Science ®Google Scholar
• [Update on current care guidelines. Rheumatoid Arthritis (RA)]. Duodecim 2015;131:1409–10.
   PubMedGoogle Scholar
• Sokka T, Toloza S, Cutolo M, Kautiainen H, Makinen H, Gogus F, et al. Women, men, and rheumatoid arthritis: analyses of disease activity, disease characteristics, and treatments in the QUEST-RA study. Arthritis Res Ther 2009;11:R7.
   PubMed Web of Science ®Google Scholar
• Aktas A, Walsh D, Rybicki L. Symptom clusters: myth or reality? Palliat Med 2010;24:373–85.
   PubMed Web of Science ®Google Scholar