Assessment of imidacloprid toxicity on reproductive organ system of adult male rats

References

• Aitken , R. J. , Koopman , P. and Lewis , S. E. 2004 . Seeds of concern . Nature , 432 ( 7013 ) : 48 – 52 .
   PubMed Web of Science ®Google Scholar
• Matsuda , K. , Buckingham , S. D. , Kleier , D. , Rauh , J. J. , Grauso , M. and Sattelle , D. B. 2001 . Neonicotinoids: insecticides acting on insect nicotinic acetylcholine receptors . Trends Pharmacol. Sci. , 22 ( 11 ) : 573 – 80 .
   PubMed Web of Science ®Google Scholar
• Dani , J. A. and De Biasi , M. 2001 . Cellular mechanisms of nicotine addiction . Pharmacol. Biochem. Behav. , 70 ( 4 ) : 439 – 46 .
   PubMed Web of Science ®Google Scholar
• Zwart , R. , Abraham , D. , Oortgiesen , M. and Vijverberg , H. P. 1994 . Alpha 4 beta 2 subunit combination specific pharmacology of neuronal nicotinic acetylcholine receptors in N1E-115 neuroblastoma cells . Brain Res. , 654 ( 2 ) : 312 – 8 .
   PubMed Web of Science ®Google Scholar
• Bal , R. , Erdogan , S. , Theophilidis , G. , Baydas , G. and Naziroglu , M. 2010 . Assessing the effects of the neonicotinoid insecticide imidacloprid in the cholinergic synapses of the stellate cells of the mouse cochlear nucleus using whole-cell patch-clamp recording . Neurotoxicology , 31 ( 1 ) : 113 – 20 .
   PubMed Web of Science ®Google Scholar
• Matsuda , K. , Buckingham , S. D. , Freeman , J. C. , Squire , M. D. , Baylis , H. A. and Sattelle , D. B. 1998 . Effects of the alpha subunit on imidacloprid sensitivity of recombinant nicotinic acetylcholine receptors . Br. J. Pharmacol. , 123 ( 3 ) : 518 – 24 .
   PubMed Web of Science ®Google Scholar
• Abreu-Villaca , Y. , Seidler , F. J. , Qiao , D. and Slotkin , T. A. 2005 . Modeling the developmental neurotoxicity of nicotine in vitro: cell acquisition, growth and viability in PC12 cells . Brain Res. Dev. Brain Res. , 154 ( 2 ) : 239 – 46 .
   PubMedGoogle Scholar
• Nagata , K. , Song , J. H. , Shono , T. and Narahashi , T. 1998 . Modulation of the neuronal nicotinic acetylcholine receptor-channel by the nitromethylene heterocycle imidacloprid . J. Pharmacol. Exp. Ther. , 285 ( 2 ) : 731 – 8 .
   PubMed Web of Science ®Google Scholar
• Tomlin , C. D. and Tomlin , S. The Pesticide Manual , The British Crop Protection Council, Surrey, UK . 1997
   Google Scholar
• Bal , R. , Baydas , G. and Naziroglu , M. 2009 . Electrophysiological properties of ventral cochlear nucleus neurons of the dog . Hear. Res. , 256 ( 1-2 ) : 93 – 103 .
   PubMed Web of Science ®Google Scholar
• Bal , R. and Baydas , G. 2009 . Electrophysiological properties of octopus neurons of the cat cochlear nucleus: an in vitro study . J. Assoc. Res. Otolaryngol. , 10 ( 2 ) : 281 – 93 .
   PubMed Web of Science ®Google Scholar
• Bal , R. and Oertel , D. 2000 . Hyperpolarization-activated, mixed-cation current (I(h)) in octopus cells of the mammalian cochlear nucleus . J. Neurophysiol. , 84 ( 2 ) : 806 – 17 .
   PubMed Web of Science ®Google Scholar
• Bal , R. and Oertel , D. 2001 . Potassium currents in octopus cells of the mammalian cochlear nucleus . J. Neurophysiol. , 86 ( 5 ) : 2299 – 311 .
   PubMed Web of Science ®Google Scholar
• Bal , R. and Oertel , D. 2007 . Voltage-activated calcium currents in octopus cells of the mouse cochlear nucleus . J. Assoc. Res. Otolaryngol. , 8 ( 4 ) : 509 – 21 .
   PubMed Web of Science ®Google Scholar
• Oertel , D. , Bal , R. , Gardner , S. M. , Smith , P. H. and Joris , P. X. 2000 . Detection of synchrony in the activity of auditory nerve fibers by octopus cells of the mammalian cochlear nucleus . Proc. Natl. Acad. Sci. USA , 97 ( 22 ) : 11773 – 9 .
   PubMed Web of Science ®Google Scholar
• Oertel , D. , Wright , S. , Cao , X. J. , Ferragamo , M. and Bal , R. 2011 . The multiple functions of T stellate/multipolar/chopper cells in the ventral cochlear nucleus . Hear. Res. , 276 ( 1-2 ) : 61 – 9 .
   PubMed Web of Science ®Google Scholar
• Nauen , R. , Ebbinghaus-Kintscher , U. and Schmuck , R. 2001 . Toxicity and nicotinic acetylcholine receptor interaction of imidacloprid and its metabolites in Apis mellifera (Hymenoptera: Apidae) . Pest. Manag. Sci. , 57 ( 7 ) : 577 – 86 .
   PubMed Web of Science ®Google Scholar
• Abou-Donia , M. B. , Goldstein , L. B. , Bullman , S. , Tu , T. , Khan , W. A. , Dechkovskaia , A. M. and Abdel-Rahman , A. A. 2008 . Imidacloprid induces neurobehavioral deficits and increases expression of glial fibrillary acidic protein in the motor cortex and hippocampus in offspring rats following in utero exposure . J. Toxicol. Environ. Health. A , 71 ( 2 ) : 119 – 30 .
   PubMed Web of Science ®Google Scholar
• Karabay , N. U. and Oguz , M. G. 2005 . Cytogenetic and genotoxic effects of the insecticides, imidacloprid and methamidophos . Genet Mol Res , 4 ( 4 ) : 653 – 62 .
   PubMedGoogle Scholar
• Craig , M. S. , Gupta , R. C. , Candery , T. D. and Britton , D. A. 2005 . Human exposure to imidacloprid from dogs treated with advantage(r) . Toxicol. Mech. Methods , 15 ( 4 ) : 287 – 91 .
   PubMed Web of Science ®Google Scholar
• Federal Register . Imidacloprid; Pesticide Tolerances . 60 ( 128 ) 34943 – 24945 . July 5, 1995
   Google Scholar
• Turk , G. , Atessahin , A. , Sonmez , M. , Ceribasi , A. O. and Yuce , A. 2008 . Improvement of cisplatin-induced injuries to sperm quality, the oxidant-antioxidant system, and the histologic structure of the rat testis by ellagic acid . Fertil. Steril. , 89 ( 5 Suppl ) : 1474 – 81 .
   PubMed Web of Science ®Google Scholar
• Niehaus , W. G. Jr. and Samuelsson , B. 1968 . Formation of malonaldehyde from phospholipid arachidonate during microsomal lipid peroxidation . Eur. J. Biochem. , 6 ( 1 ) : 126 – 30 .
   PubMedGoogle Scholar
• de las Heras , A. , Schoch , A. M. and Fischer , A. 2003 . Comparison of methods for determining malondialdehyde in dry sausage by HPLC and the classic TBA test . Eur. Food Res. Technol. , 217 : 180 – 184 .
   Web of Science ®Google Scholar
• Ellman , G. L. 1959 . Tissue sulfhydryl groups . Arch. Biochem. Biophys. , 82 ( 1 ) : 70 – 7 .
   PubMed Web of Science ®Google Scholar
• Akerboom , T. P. and Sies , H. 1981 . Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples . Methods Enzymol. , 77 : 373 – 82 .
   PubMedGoogle Scholar
• Hara , A. and Radin , N. S. 1978 . Lipid extraction of tissues with a low-toxicity solvent . Anal. Biochem. , 90 ( 1 ) : 420 – 6 .
   PubMed Web of Science ®Google Scholar
• Christie , W. W. 1992 . Gas chromatography and lipids , Glasgow : The Oily Press .
   Google Scholar
• Sanchez-Machado , D. I. , Lopez-Hernandez , J. , Paseiro-Losada , P. and Lopez-Cervantes , J. 2004 . An HPLC method for the quantification of sterols in edible seaweeds . Biomed. Chromatogr. , 18 ( 3 ) : 183 – 90 .
   PubMed Web of Science ®Google Scholar
• Lopez-Cervantes , J. , Sanchez-Machado , D. I. and Rios-Vazquez , N. J. 2006 . High-performance liquid chromatography method for the simultaneous quantification of retinol, alpha-tocopherol, and cholesterol in shrimp waste hydrolysate . J. Chromatogr. A , 1105 ( 1-2 ) : 135 – 9 .
   PubMed Web of Science ®Google Scholar
• Wang , J. Y. , Shum , A. Y. , Ho , Y. J. and Wang , J. Y. 2003 . Oxidative neurotoxicity in rat cerebral cortex neurons: synergistic effects of H2O2 and NO on apoptosis involving activation of p38 mitogen-activated protein kinase and caspase-3 . J. Neurosci. Res. , 72 ( 4 ) : 508 – 19 .
   PubMed Web of Science ®Google Scholar
• Klinefelter , G. R. and Hess , R. A. 1998 . “ Toxicology of the male excurrent ducts and accessory sex glands ” . In Reproductive and Developmental Toxicology Edited by: Kenneth , S. K. 553 – 559 . Marcel Dekker , New York
   Google Scholar
• Narayana , K. , Prashanthi , N. , Nayanatara , A. , Bairy , L. K. and D’Souza , U. J. 2006 . An organophosphate insecticide methyl parathion (o- o- dimethyl o-4-nitrophenyl phosphorothioate) induces cytotoxic damage and tubular atrophy in the testis despite elevated testosterone level in the rat . J. Toxicol. Sci. , 31 ( 3 ) : 177 – 89 .
   PubMedGoogle Scholar
• Marra , C. A. and de Alaniz , M. J. 1989 . Influence of testosterone administration on the biosynthesis of unsaturated fatty acids in male and female rats . Lipids , 24 ( 12 ) : 1014 – 9 .
   PubMed Web of Science ®Google Scholar
• Bedford , J. M. 1983 . Significance of the need for sperm capacitation before fertilization in eutherian mammals . Biol. Reprod. , 28 ( 1 ) : 108 – 20 .
   PubMed Web of Science ®Google Scholar
• Bai , J. P. and Shi , Y. L. 2002 . Inhibition of Ca(2+) channels in mouse spermatogenic cells by male antifertility compounds from Tripterygium wilfordii Hook. f . Contraception , 65 ( 6 ) : 441 – 5 .
   PubMed Web of Science ®Google Scholar
• Akbarsha , M. A. , Latha , P. N. and Murugaian , P. 2000 . Retention of cytoplasmic droplet by rat cauda epididymal spermatozoa after treatment with cytotoxic and xenobiotic agents . J. Reprod. Fertil. , 120 ( 2 ) : 385 – 90 .
   PubMedGoogle Scholar
• Matsumoto , M. , Hirose , A. and Ema , M. 2008 . Review of testicular toxicity of dinitrophenolic compounds, 2-sec-butyl-4,6-dinitrophenol, 4,6-dinitro-o-cresol and 2,4-dinitrophenol . Reprod. Toxicol. , 26 ( 3–4 ) : 185 – 90 .
   PubMed Web of Science ®Google Scholar
• Carlsen , E. , Giwercman , A. , Keiding , N. and Skakkebaek , N. E. 1992 . Evidence for decreasing quality of semen during past 50 years . B.M.J. , 305 ( 6854 ) : 609 – 13 .
   PubMed Web of Science ®Google Scholar
• Bebb , R. A. , Anawalt , B. D. , Christensen , R. B. , Paulsen , C. A. , Bremner , W. J. and Matsumoto , A. M. 1996 . Combined administration of levonorgestrel and testosterone induces more rapid and effective suppression of spermatogenesis than testosterone alone: a promising male contraceptive approach . J. Clin. Endocrinol. Metab. , 81 ( 2 ) : 757 – 62 .
   PubMed Web of Science ®Google Scholar
• Sinha , N. , Narayan , R. , Shanker , R. and Saxena , D. K. 1995 . Endosulfan-induced biochemical changes in the testis of rats . Vet. Hum. Toxicol. , 37 ( 6 ) : 547 – 9 .
   PubMedGoogle Scholar
• Mahgoub , A. A. and El-Medany , A. H. 2001 . Evaluation of chronic exposure of the male rat reproductive system to the insecticide methomyl . Pharmacol. Res. , 44 ( 2 ) : 73 – 80 .
   PubMed Web of Science ®Google Scholar
• Khokha , A. M. , Kashko , M. F. and Voronov , P. P. 1993 . Effect of ethanol and lipid peroxidation on testosterone biosynthesis by interstitial cells of rat testes . Ukr. Biokhim. Zh. , 65 ( 4 ) : 111 – 5 .
   PubMedGoogle Scholar
• Gunnarsson , D. , Svensson , M. , Selstam , G. and Nordberg , G. 2004 . Pronounced induction of testicular PGF(2 alpha) and suppression of testosterone by cadmium-prevention by zinc . Toxicology , 200 ( 1 ) : 49 – 58 .
   PubMed Web of Science ®Google Scholar
• Sujatha , R. , Chitra , K. C. , Latchoumycandae , C. and Mathur , P. P. 2001 . Effect of lindane on testicular antioxidant system and steroidogenic enzymes in adult rats . Asian J. Androl. , 3 ( 2 ) : 135 – 8 .
   PubMed Web of Science ®Google Scholar
• Latchoumycandane , C. , Chitra , C. and Mathur , P. 2002 . Induction of oxidative stress in rat epididymal sperm after exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin . Arch. Toxicol. , 76 ( 2 ) : 113 – 8 .
   PubMed Web of Science ®Google Scholar
• Saradha , B. and Mathur , P. P. 2006 . Effect of environmental contaminants on male reproduction . Environ. Toxicol. Pharmacol. , 21 : 34 – 41 .
   PubMed Web of Science ®Google Scholar
• Carpenter , M. P. 1971 . The lipid composition of maturing rat testis. The effect of alpha-tocopherol . Biochim. Biophys. Acta , 231 ( 1 ) : 52 – 79 .
   PubMed Web of Science ®Google Scholar
• Samanta , L. and Chainy , G. B. 1997 . Comparison of hexachlorocyclohexane-induced oxidative stress in the testis of immature and adult rats . Comp. Biochem. Physiol. C Pharmacol. Toxicol. Endocrinol. , 118 ( 3 ) : 319 – 27 .
   PubMed Web of Science ®Google Scholar
• Caliskan , A. M. , Naziroglu , M. , Uguz , A. C. , Ovey , I. S. , Sütçü , R. , Bal , R. , Calişkan , S. and Ozcankaya , R. 2010 . Acamprosate modulates alcohol-induced hippocampal NMDA receptors and brain microsomal Ca2+-ATPase but induces oxidative stress in rat . J. Membr. Biol. , 237 ( 1 ) : 51 – 8 .
   PubMed Web of Science ®Google Scholar
• Naziroglu , M. , Kutluhan , S. , Uguz , A. C. , Celik , O. , Bal , R. and Butterworth , P. J. 2009 . Topiramate and vitamin e modulate the electroencephalographic records, brain microsomal and blood antioxidant redox system in pentylentetrazol-induced seizure of rats . J. Membr. Biol. , 229 ( 3 ) : 131 – 40 .
   PubMed Web of Science ®Google Scholar
• Naziroglu , M. , Uguz , A. C. , Kocak , A. and Bal , R. 2009 . Acetaminophen at different doses protects brain microsomal Ca2+-ATPase and the antioxidant redox system in rats . J. Membr. Biol. , 231 ( 2-3 ) : 57 – 64 .
   PubMed Web of Science ®Google Scholar
• Naziroglu , M. , Kilinc , F. , Uguz , A. C. , Celik , O. , Bal , R. , Butterworth , P. J. and Baydar , M. L. 2010 . Oral vitamin C and E combination modulates blood lipid peroxidation and antioxidant vitamin levels in maximal exercising basketball players . Cell. Biochem. Funct. , 28 ( 4 ) : 300 – 305 .
   PubMed Web of Science ®Google Scholar
• Debnath , D. and Mandal , T. K. 2000 . Study of quinalphos (an environmental oestrogenic insecticide) formulation (Ekalux 25 E.C.)-induced damage of the testicular tissues and antioxidant defence systems in Sprague-Dawley albino rats . J. Appl. Toxicol. , 20 ( 3 ) : 197 – 204 .
   PubMed Web of Science ®Google Scholar
• Kehrer , J. P. 1993 . Free radicals as mediators of tissue injury and disease . Crit. Rev. Toxicol. , 23 ( 1 ) : 21 – 48 .
   PubMed Web of Science ®Google Scholar
• Yener , Z. , Celik , I. , Ilhan , F. and Bal , R. 2009 . Effects of Urtica dioica L. seed on lipid peroxidation, antioxidants and liver pathology in aflatoxin-induced tissue injury in rats . Food Chem. Toxicol. , 47 ( 2 ) : 418 – 24 .
   PubMed Web of Science ®Google Scholar
• Altug , M. E. , Serarslan , Y. , Bal , R. , Kontaş , T. , Ekici , F. , Melek , I. M. , Aslan , H. and Duman , T. 2008 . Caffeic acid phenethyl ester protects rabbit brains against permanent focal ischemia by antioxidant action: a biochemical and planimetric study . Brain Res. , 1201 : 135 – 42 .
   PubMed Web of Science ®Google Scholar
• Dohle , G. R. , Smit , M. and Weber , R. F. 2003 . Androgens and male fertility . World J. Urol. , 21 ( 5 ) : 341 – 5 .
   PubMed Web of Science ®Google Scholar
• Lu , Z. H. , Mu , Y. M. , Wang , B. A. , Li , X. L. , Lu , J. M. , Li , J. Y. , Pan , C. Y. , Yanase , T. and Nawata , H. 2003 . Saturated free fatty acids, palmitic acid and stearic acid, induce apoptosis by stimulation of ceramide generation in rat testicular Leydig cell . Biochem. Biophys. Res. Commun. , 303 ( 4 ) : 1002 – 7 .
   PubMed Web of Science ®Google Scholar
• Bal , R. , Turk , G. , Tuzcu , M. , Yilmaz , O. , Ozercan , I. , Kuloglu , T. , Gür , S. , Nedzvetsky , V. S. , Tykhomyrov , A. A. , Andrievsky , G. V. , Baydas , G. and Naziroglu , M. 2011 . Protective effects of nanostructures of hydrated C(60) fullerene on reproductive function in streptozotocin-diabetic male rats . Toxicology , 282 ( 3 ) : 69 – 81 .
   PubMed Web of Science ®Google Scholar
• Miller , R. R. Jr. , Heckel , C. D. , Koss , W. J. , Montague , S. L. and Greenman , A. L. 2001 . Ethanol- and nicotine-induced membrane changes in embryonic and neonatal chick brains . Comp. Biochem. Physiol. C Toxicol. Pharmacol. , 130 ( 2 ) : 163 – 78 .
   PubMed Web of Science ®Google Scholar
• Payne , A. H. and Hales , D. B. 2004 . Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones . Endocr. Rev. , 25 ( 6 ) : 947 – 70 .
   PubMed Web of Science ®Google Scholar
• Diniz , Y. S. , Cicogna , A. C. , Padovani , C. R. , Santana , L. S. , Faine , L. A. and Novelli , E. L. 2004 . Diets rich in saturated and polyunsaturated fatty acids: metabolic shifting and cardiac health . Nutrition , 20 ( 2 ) : 230 – 4 .
   PubMed Web of Science ®Google Scholar
• Gutteridge , J. M. , Quinlan , G. J. and Yamamoto , Y. 1998 . Hypothesis: are fatty acid patterns characteristic of essential fatty acid deficiency indicative of oxidative stress? . Free Radic. Res. , 28 ( 2 ) : 109 – 14 .
   PubMed Web of Science ®Google Scholar
• Vento , R. , D’Alessandro , N. , Giuliano , M. , Lauricella , M. , Carabillo , M. and Tesoriere , G. 2000 . Induction of apoptosis by arachidonic acid in human retinoblastoma Y79 cells: involvement of oxidative stress . Exp. Eye. Res. , 70 ( 4 ) : 503 – 17 .
   PubMed Web of Science ®Google Scholar
• Bourre , J. M. , Dumont , O. L. , Clement , M. E. and Durand , G. A. 1997 . Endogenous synthesis cannot compensate for absence of dietary oleic acid in rats . J. Nutr. , 127 ( 3 ) : 488 – 93 .
   PubMed Web of Science ®Google Scholar
• Meikle , A. W. , Cardoso de Sousa , J. C. , Hanzalova , J. and Murray , D. K. 1996 . Oleic acid inhibits cholesteryl esterase and cholesterol utilization for testosterone synthesis in mouse Leydig cells . Metabolism , 45 ( 3 ) : 293 – 9 .
   PubMed Web of Science ®Google Scholar
• Hurtado de Catalfo , G. E. and de Gomez Dumm , I. N. 2005 . Influence of testosterone on polyunsaturated fatty acid biosynthesis in Sertoli cells in culture . Cell Biochem. Funct. , 23 ( 3 ) : 175 – 80 .
   PubMed Web of Science ®Google Scholar