Fate and distribution of fipronil on companion animals and in their indoor residences following spot-on flea treatments

References

• Driver , J. H. , Ross , J. H. , Bigelow Dyk , M. M. , Guerino , F. , Holden , L. and Krieger , R. 2010 . “ Pet care products used for insect pest control ” . In Handbook of Pesticide Toxicology, , 3rd Edition , Vol. 1 , 1077 – 1090 . San Diego , CA : Academic Press .
   Google Scholar
• Lee , S.-J. , Mulay , P. , Diebolt-Brown , B. , Lackovic , M. J. , Mehler , L. N. , Beckman , J. , Waltz , J. , Prado , J. B. , Mitchell , Y. A. , Higgins , S. A. , Schwartz , A. and Calvert , G. M. 2010 . Acute illnesses associated with exposure to fipronil—surveillance data from 11 states in the United States, 2001–2007 . Clinical Toxicol. , 48 : 737 – 744 .
   Web of Science ®Google Scholar
• Cole , L. M. , Nicholson , R. A. and Casida , J. E. 1993 . Action of phenylpyrazole insecticides at the GABA-gated chloride channel . Pestic. Biochem. Physiol. , 46 : 47 – 54 .
   Web of Science ®Google Scholar
• Tingle , C. C. , Rother , J. A. , Dewhurst , C. F. , Lauer , S. and King , W. J. 2003 . Fipronil: environmental fate, ecotoxicology, and human health concerns . Rev Environ Contam Toxicol , 176 : 1 – 66 .
   PubMed Web of Science ®Google Scholar
• Jackson , D. , Cornell , C. B. , Luukinen , B. , Buhle , K. and Stone , D. 2009 . Fipronil Technical Fact Sheet , National Pesticide Information Center, Oregon State University Extension Services . Available at http://npic.orst.edu/factsheets/fiptech.pdf (retrieved April 2012)
   Google Scholar
• Gunasekara , A. S. , Tresca , T. , Goh , K. S. , Spurlock , F. and Treerdema , R. S. 2007 . Environmental fate and toxicology of fipronil . J Pest Sci , 32 : 189 – 199 .
   Web of Science ®Google Scholar
• Hainzl , D. and Casida , J. E. 1996 . Fipronil insecticide: Novel photochemical desulfinylation with retention of neurotoxicity . Proc Natl Acad Sci. , 93 : 12764 – 12767 .
   PubMed Web of Science ®Google Scholar
• Hainzl , D. , Cole , L. M. and Casida , J. E. 1998 . Mechanisms for selective toxicity of fipronil insecticide and its sulfone metabolite and desulfinyl photoproduct . Chem. Res. Toxicol. , 11 : 1529 – 1535 .
   PubMed Web of Science ®Google Scholar
• Jennings , J. A. , Canerdy , T. D. , Keller , R. J. , Atieh , B. H. , Doss , R. B. and Gupta , R. C. 2002 . Human exposure to fipronil from dogs treated with Frontline® . Vet Human Toxicol , 44 : 301 – 303 .
   PubMedGoogle Scholar
• Stout , D. M. II , Bradham , K. D. , Egeghy , P. P. , Jones , P. , Croghan , C. W. , Ashley , P. A. , Pinzer , E. , Friedman , W. , Brinkman , M. C. , Nishioka , M. G. and Cox , D. C. 2009 . American healthy homes survey: a national study of residential pesticides measured from floor wipes . Env. Sci. Tech. , 43 ( 12 ) : 4294 – 4300 .
   Web of Science ®Google Scholar
• Mahler , B. J. , Van Metre , P. C. , Wilson , J. T. , Musgrove , M. , Zaugg , S. D. and Burkhardt , M. R. 2009 . Fipronil and its Degradates in Indoor and Outdoor Dust . Environ. Sci. Technol. , 43 ( 15 ) : 5665 – 5670 .
   Web of Science ®Google Scholar
• Nishioka , M. G. , Burkholder , H. M. and Brinkman , M. C. 1999 . Distribution of 2,4-dichlorophenoxyacetic acid in floor dust throughout homes following homeowner and commercial lawn applications: quantitative effects of children, pets and shoes . Environ Sci Technol. , 33 : 1359 – 1365 .
   Web of Science ®Google Scholar
• Morgan , M. K. , Stout , D. M. II and Wilson , N. K. 2001 . Feasibility study of the potential for human exposure to pet-borne diazinon residues following lawn applications . Bull. Environ. Contam. Toxicol , 66 : 295 – 300 .
   PubMed Web of Science ®Google Scholar
• Morgan , M. K. , Stout , D. M. II , Jones , P. A. and Barr , D. A. 2008 . An observational study of the potential for human exposure to pet borne diazinon residues following lawn applications . Environ. Res. , 107 : 336 – 342 .
   PubMed Web of Science ®Google Scholar
• Bigelow Dyk , M. , Chen , Z. , Mosadeghi , S. , Vega , H. and Krieger , R. 2011 . Pilot biomonitoring of adults and children following use of chlopyrifos shampoo and flea collars on dogs . J. Environ Sci Health, Part B , 46 : 97 – 104 .
   Web of Science ®Google Scholar
• Chambers , J. E. and Davis , M. K. 2009 . “ Exposure of adults and children to organophosphorus insecticides used in flea collars on pet dogs ” . In Pesticides in Household, Structural and Residential Pest Management , Edited by: Peterson , C. J. and Stout , D. M. 163 – 173 . ACS Symposium Series, American Chemical Society, Washington, DC .
   Google Scholar
• Eaton , D. L. , Daroff , R. B. , Autrup , H. , Bridges , J. , Buffler , P. , Costa , L. G. , Coyle , J. , McKhann , G. , Mobley , W. C. , Nadel , L. , Neubert , D. , Schulte-Hermann , R. and Spencer , P. S. 2008 . Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment . Critical Reviews Toxicol , 38 : 1 – 125 .
   PubMed Web of Science ®Google Scholar
• Boone , J. S. , Tyler , J. W. and Chambers , J. E. 2001 . Transferable residue from dog fur and plasma cholinesterase inhibition in dogs treated with a flea control dip containing chlorpyrifos . Environ. Health Perspect , 109 ( 11 ) : 1109 – 1114 .
   Web of Science ®Google Scholar
• Boone , J. S , Tyler , J. and Chambers , J. E. 2002 . Exposure of children and adults to transferable residues of chlorpyrifos from dogs treated with flea control collars . Toxicol. Sci , 66 ( Suppl. ) : 346
   Google Scholar
• Craig , M. S. , Gupta , R. C. , Candery , T. D. and Britton , D. A. 2005 . Human Exposure to Imidacloprid from Dogs Treated with Advantage . Toxicol. Mech. Methods , 15 : 287 – 291 .
   PubMed Web of Science ®Google Scholar
• Gupta , R. C. , Masthay , M. B. , Canerdy , T. D. , Acosta , T. M. , Provost , R. J. , Britton , D. M. , Atieh , B. H. and Keller , R. J. 2005 . Human exposure to selamectin from dogs treated with revolution: methodological consideration for selamectin isolation . Toxicol. Mech. Methods , 15 : 317 – 321 .
   PubMed Web of Science ®Google Scholar
• Chambers , J. E. , Boone , J. S. , Davis , M. K. , Moran , J. E. and Tyler , J. W. 2007 . Assessing transferable residues from intermittent exposure to flea control collars containing the organophosphate insecticide chlorpyrifos . J. Expo. Anal. Env. Epid. , 17 : 656 – 666 .
   Google Scholar
• Davis , M. K. , Boone , J. S. , Moran , J. E. , Tyler , J. W. and Chambers , J. E. 2008 . Assessing intermittent pesticide exposure from flea control collars containing the organophosphorus insecticide tetrachlorvinphos . J. Expo. Sci. Environ. Epidemiol , 18 : 564 – 570 .
   PubMed Web of Science ®Google Scholar
• Bigelow Dyk , M. 2009 . “ Determinants of human exposure to fipronil following use as a topical flea and tick treatment of companion animals. PhD Dissertation ” . Riverside , CA : University of California Riverside .
   Google Scholar
• Ngim , K. K. and Crosby , D. G. 2001 . Abiotic processes influencing fipronil and desthiofipronil dissipation in California, USA, rice fields . Environ. Toxicol. Chem. , 20 ( 5 ) : 972 – 977 .
   Web of Science ®Google Scholar
• Ross , J. , Chester , G. , Driver , J. , Lunchick , C. , Holden , L. , Rosenheck , L. and Barnekow , D. 2008 . Comparative evaluation of absorbed dose estimates derived from passive dosimetry measurements to those derived from biological monitoring: validation of exposure monitoring methodologies . J. Expo. Sci. Environ. Epidemiol , 18 : 211 – 230 .
   PubMed Web of Science ®Google Scholar
• Li , Y. , Chen , L. , Chen , Z. , Coehlo , J. , Cui , L. , Lopez , T. , Sankaran , G. , Vega , H. and Krieger , R. I. 2011 . Glove accumulation of pesticide residues for strawberry harvester exposure assessment . Bull Environ. Contam. Toxicol , 86 : 615 – 620 .
   PubMed Web of Science ®Google Scholar
• Bernard , C. E. , Nuygen , H. , Truong , D. and Krieger , R. I. 2001 . Environmental residues and biomonitoring estimates of human insecticide exposure from treated residential turf . Arch. Environ. Contam. Toxicol , 41 : 237 – 240 .
   PubMed Web of Science ®Google Scholar
• Williams , R. L. 2002 . “ The Influence of Moisture on Indoor Pesticide Exposure of Humans Using Chlorpyrifos. A Model Semi-Volatile Pesticide. Ph.D Dissertation ” . Riverside , CA : University of California-Riverside .
   Google Scholar
• Tulve , N. S. , Egeghy , P. P. , Fortmann , R. C. , Whitaker , D. A. , Nishioka , M. G. , Naeher , L. P. and Hilliard , A. 2008 . Multimedia measurements and activity patterns in an observational pilot study of nine young children . J. Exp. Sci. Environ. Epidemiol , 18 : 31 – 44 .
   Web of Science ®Google Scholar
• Driver , J. , Ross , J. , Mihlan , G. , Lunchick , C. and Landenberger , B. 2007 . Derivation of single layer clothing penetration factors from the pesticide handlers exposure database . Regulatory Toxicology and Pharmacology , 49 : 125 – 137 .
   PubMed Web of Science ®Google Scholar
• Fenske , R. A. , Birbuam , S. G. , Methner , M. M. and Soto , R. 1989 . Methods for assessing fieldworker hand exposer to pesticides during peach harvesting . Bull. Environ. Contam. Toxicol , 43 : 805 – 813 .
   PubMed Web of Science ®Google Scholar
• Williams , R. L. , Bernard , C. E. and Krieger , R. I. 2003 . Human exposure to indoor residential cyfluthrin residues during a structured activity program . J. Expo. Anal. Environ. Epidemiol , 13 : 112 – 119 .
   PubMedGoogle Scholar
• Mohamed , F. , Senarathna , L. , Percy , A. , Abeyewardene , M. , Eaglesham , G. , Cheng , R. , Azher , S , Hittarage , A , Dissanayake , W , Sheriff , M. H , Davies , W , Buckley , N. A and Eddleston , M . 2004 . Acute human self-poisoning with the N-phenylpyrazole insecticide fipronil—a GABAA-gated chloride channel blocker . J Toxicol Clin Toxicol , 42 : 955 – 963 .
   PubMed Web of Science ®Google Scholar
• Tang , J. , Usmani , A. , Hodgson , E. and Rose , R. L. 2004 . In vitro metabolism of fipronil by human and rat cytochrome P450 and its interactions with testosterone and diazepam . Chem-Biol Interact , 147 : 319 – 329 .
   PubMed Web of Science ®Google Scholar