Publication Cover
Journal of Environmental Science and Health, Part B
Pesticides, Food Contaminants, and Agricultural Wastes
Volume 49, 2014 - Issue 4
185
Views
6
CrossRef citations to date
0
Altmetric
Original Articles

Effect of 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine on oxidative stress and gene expression of c-fos, c-jun, p16 and Rb in rat colons and protective role of seabuckthorn seed oil

, , , &
Pages 279-289 | Received 25 Jun 2013, Published online: 06 Feb 2014

References

  • Jahurul , M. H.A. , Jinap , S. , Ang , S. J. , Abdul-Hamid , A. , Hajeb , P. , Lioe , H. N. and Zaidul , I. S.M. 2010 . Dietary exposure to heterocyclic amines in high-temperature cooked meat and fish in Malaysia . Food Addit. Contam. A , 27 : 1060 – 1071 .
  • National Toxicology Program . 2011 . “ U.S. Department of Health and Human Services Public Health Service ” . 220 – 222 . Report on Carcinogens
  • Wakabayashi , K. , Ushizima , H. , Takahashi , M. , Nukaya , H. , Kim , S. B. , Hirose , M. , Ochiai , M. , Sugimura , T. and Nagao , M. 1993 . Exposure to heterocyclic amines . Environ. Health Perspect , 99 : 129 – 134 .
  • Spandidos , D. A. 2007 . Oncogenes and tumor suppressor genes as paradigms in oncogenesis . J. BUON , 12 : S9 – S12 .
  • Klaunig , J. E. , Wang , Z. , Pu , X. and Zhou , S. 2010 . Oxidative stress and oxidative damage in chemical carcinogenesis . Toxicol. Appl. Pharmacol , 254 : 86 – 99 .
  • Imlay , J. A. and Linn , S. 1998 . DNA damage and oxygen radical toxicity . Science , 240 : 1302 – 1309 .
  • Nakagama , H. , Nakanishi , M. and Ochiai , M. 2005 . Modeling human colon cancer in rodents using a food-borne carcinogen, PhIP . Cancer Sci. , 96 : 627 – 636 .
  • Rohrmann , S. , Hermann , S. and Linseisen , J. 2009 . Heterocyclic aromatic amine intake increases colorectal adenoma risk: Finding from a prospective European cohort study . Am. J. Clin. Nutr , 89 : 1418 – 1424 .
  • Negi , P. S. , Chauhan , A. S. , Sadia , G. A. , Rohinishree , Y. S. and Ramteke , R. S. 2005 . Antioxidant and antibacterial activities of various seabuckthorn (Hippophae rhamnoides L.) seed extracts . Food Chem. , 92 : 119 – 124 .
  • Basu , M. , Prasad , R. , Jayamurthy , P. , Pal , K. , Arumughan , C. and Sawhney , R. C. 2007 . Anti-atherogenic effects of seabuckthorn (Hippophaea rhamnoides) seed oil . Phytomedicine , 14 : 770 – 777 .
  • Yang , B. and Kallio , H. 2002 . Composition and physiological effects of seabuckthorn (Hippophae) lipids . Trends Food Sci. Tech , 13 : 160 – 167 .
  • Li , R. , Li , W. , Xie , J. and Zhang , Y. 2012 . Lipid peroxidation in different tissues of rats treated with 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine . J. Hyg. Res , 41 : 102 – 105 .
  • Lin , D. X. , Xiao , Y. , Tan , W. , Kadlubar , F. F. and Chen , J. S. 1998 . Chemoprotection by green tea against the formation of food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine (PhIP)-DNA adducts in rats . Chin. J. Prev. Med , 32 : 261 – 264 .
  • Wu , D. and Meng , Z. 2003 . Effect of sulfur dioxide inhalation on the glutathione redox system in mice and protective role of Sea Buckthorn seed oil . Arch. Environ. Contam. Toxicol , 45 : 423 – 428 .
  • Xie , J. , Fan , R. and Meng , Z. 2007 . Protein oxidation and DNA-protein crosslink induced by sulfur dioxide in lungs,livers,and hearts from mice . Inhal. Toxicol , 19 : 759 – 765 .
  • Dubuisson , J. and Gaubatz , J. 1998 . Bioactivation of the proximal food mutagen 2-hydroxyamino-1-methyl-6-phenylimidazo [4, 5-b] pyridine (N-OH-PhIP) to DNA binding species by human mammary gland enzymes . Nutrition , 14 : 710 – 712 .
  • Moonen , H. J. , Briedé , J. J. , van Maanen , J. M. , Kleinjans , J. C. and de Kok , T. M. 2002 . Generation of free radicals and induction of DNA adducts by activation of heterocyclic aromatic amines via different metabolic pathways in vitro . Mol. Carcinog , 35 : 196 – 203 .
  • Choudhary , S. , Sood , S. , Donnell , R. L. and Wang , H. C. 2012 . Intervention of human breast cell carcinogenesis chronically induced by 2-amino-1-methyl-6-phenylimidazo [4, 5-b]pyridine . Carcinogenesis , 33 : 876 – 885 .
  • Wilson , C. , Aboyade-Cole , A. , Newell , O. , Darling-Reed , S. , Oriaku , E. and Thomas , R. 2007 . Diallyl sulfide inhibits PhIP-induced DNA strand breaks in normal human breast epithelial cells . Oncol. Rep , 17 : 807 – 811 .
  • van Loon , A. P. , Pesold-Hurt , B. and Schatz , G. 1986 . A yeast mutant lacking mitochondrial manganese superoxide dismutase is hypersensitive to oxygen . Proc. Natl. Acad. Sci. USA , 83 : 3820 – 3824 .
  • Chance , B. , Sies , H. and Boveris , A. 1979 . Hydroperoxide metabolism in mammalian organs . Physiol. Rev , 59 : 527 – 605 .
  • Pirinccioglu , A. G. , Gökalp , D. , Pirinccioglu , M. , Kizil , G. and Kizil , M. 2010 . Malondialdehyde (MDA) and protein carbonyl (PCO) levels as biomarkers of oxidative stress in subjects with familial hypercholesterolemia . Clin. Biochem , 43 : 1220 – 1224 .
  • Birben , E. , Sahiner , U. M. , Sackesen , C. , Erzurum , S. and Kalayci , O. 2012 . Oxidative stress and antioxidant defense . World Allergy Organ J , 5 : 9 – 19 .
  • Jena , N. R. 2012 . DNA damage by reactive species: Mechanisms, mutation and repair . J. Biosci , 37 : 503 – 517 .
  • Kanna , P. S. , Saralaya , M. G. , Samanta , K. and Chatterjee , M. 2005 . Vanadium inhibits DNA-protein cross-links and ameliorates surface level changes of aberrant crypt foci during 1, 2-dimethylhydrazine induced rat colon carcinogenesis . Cell Biol. Toxicol , 21 : 41 – 52 .
  • Keshavarzian , A. , Zapeda , D. , List , T. and Mobarhan , S. 1992 . High levels of reactive oxygen metabolites in colon cancer tissue: Analysis by chemiluminescence probe . Nutr. Cancer , 17 : 243 – 249 .
  • Dingley , K. H. , Curtis , K. D. , Nowell , S. , Felton , J. S. , Lang , N. P. and Turteltaub , K. W. 1999 . DNA and protein adduct formation in the colon and blood of humans after exposure to a dietary-relevant dose of 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine . Cancer Epidemiol. Biomarkers Prev , 8 : 507 – 512 .
  • Fede , J. M. , Thakur , A. P. , Gooderham , N. J. and Turesky , R. J. 2009 . Biomonitoring of 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine (PhIP) and its carcinogenic metabolites in urine . Chem. Res. Toxicol , 22 : 1096 – 1105 .
  • Malfatti , M. A. , Dingley , K. H. , Nowell-Kadlubar , S. , Ubick , E. A. , Mulakken , N. , Nelson , D. , Lang , N. P. , Felton , J. S. and Turteltaub , K. W. 2006 . The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine is predictive of colon DNA adducts after a low-dose exposure in humans . Cancer Res , 66 : 10541 – 10547 .
  • Kurzawa-Zegota , M. , Najafzadeh , M. , Baumgartner , A. and Anderson , D. 2012 . The protective effect of the flavonoids on food-mutagen-induced DNA damage in peripheral blood lymphocytes from colon cancer patients . Food Chem. Toxicol , 50 : 124 – 129 .
  • Ochiai , M. , Watanabe , M. , Kushida , H. , Wakabayashi , K. , Sugimura , T. and Nagao , M. 1996 . DNA adduct formation, cell proliferation and aberrant crypt focus formation induced by PhIP in male and female rat colon with relevance to carcinogenesis . Carcinogenesis , 17 : 95 – 98 .
  • Wieland , E. , Oellerich , M. , Braun , F. and Schtüz , E. 2000 . c-fos and c-jun mRNA expression in a pig liver model of ischemia/reperfusion: Effect of extended cold storage and the antioxidant idebenone . Clin. Biochem , 33 : 285 – 290 .
  • Reddy , S. P. and Mossmann , B. T. 2002 . Role and regulation of activator protein-1 in toxicant-induced responses of the lung . Am. J. Physiol. Lung Cell Mol. Physiol , 283 : L1161 – L1178 .
  • Pandey , S. , Gordon , P. H. and Wang , E. 1995 . Expression of proliferation-specific genes in the mucosa adjacent to colon carcinoma . Dis. Colon Rectum , 38 : 462 – 467 .
  • Russo , A. A. , Tong , L. , Lee , J. O. , Jeffrey , P. D. and Pavletich , N. P. 1998 . Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a . Nature , 395 : 237 – 243 .
  • Tada , T. , Watanabe , T. , Kazama , S. , Kanazawa , T. , Hata , K. , Komuro , Y. and Nagawa , H. 2003 . Reduced p16 expression correlates with lymphatic invasion in colorectal cancers . Hepatogastroenterology , 50 : 1756 – 1760 .
  • Weinberg , R. A. 1995 . The retinoblastoma protein and cell cycle control . Cell , 81 : 323 – 330 .
  • Tsang , W. P. , Ng , E. K. , Ng , S. S. , Jin , H. , Yu , J. , Sung , J. J. and Kwok , T. T. 2011 . Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer . Carcinogenesis , 31 : 350 – 358 .
  • Ayhan , S. , Isisag , A. , Saruc , M. , Nese , N. , Demir , M. A. and Kucukmetin , N. T. 2010 . The role of pRB, p16 and cyclin D1 in colonic carcinogenesis . Hepatogastroenterology , 57 : 251 – 256 .
  • Maki , A. , Berezesky , I. K. , Fargnoli , J. , Holbrrok , N. J. and Trump , B. F. 1992 . Role of [Ca2+]i in induction of c-fos, c-jun, and c-myc mRNA in rat PTE after oxidative stress . FASEB J , 6 : 919 – 924 .
  • Toyokuni , S. 2008 . Molecular mechanisms of oxidative stress-induced carcinogenesis: From epidemiology to oxygenomics . IUBMB Life , 60 : 441 – 447 .
  • Tope , A. M. and Panemangalore , M. 2007 . Assessment of oxidative stress due to exposure to pesticides in plasma and urine of traditional limited-resource farm workers: Formation of the DNA-adduct 8-hydroxy-2-deoxy-guanosine (8-OHdG) . J. Environ. Sci. Health Part B, , 42 : 151 – 155 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.