Mechanisms Regulating Human FMO3 Transcription

REFERENCES

• Aden D. P., Fogel A., Plotkin S., Damjanov I., Knowles B. B. Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line. Nature 1979; 282: 615–616
   PubMed Web of Science ®Google Scholar
• Andrews N. C. The NF-E2 transcription factor. Int. J. Biochem. Cell Biol. 1998; 30: 429–432
   PubMed Web of Science ®Google Scholar
• Ayesh R., Mitchell S. C., Smith R. L. Dysfunctional N-oxidation of trimethylamine and the influence of testosterone treatment in man. Pharmacogenetics 1995; 5: 244–246
   PubMedGoogle Scholar
• Boucher P. D., Ruch R. J., Hines R. N. Specific nuclear protein binding to a negative regulatory element on the human CYP1A1 gene. J. Biol. Chem. 1993; 268: 17384–17391
   PubMed Web of Science ®Google Scholar
• Cashman J. R. Structural and catalytic properties of the mammalian flavin-containing monooxygenase. Chem. Res. Toxicol. 1995; 8: 165–181
   Web of Science ®Google Scholar
• Cashman J. R. Human flavin-containing monooxygenase (form 3): Polymorphisms and variations in chemical metabolism. Pharmacogenomics 2002; 3: 325–339
   PubMed Web of Science ®Google Scholar
• Corre S., Galibert M. D. Upstream stimulating factors: highly versatile stress-responsive transcription factors. Pigment Cell Res. 2005; 18: 337–348
   PubMedGoogle Scholar
• Dorn A., Bollekens J., Staub A., Benoist C., Mathis D. A multiplicity of CCAAT box-binding proteins. Cell 1987; 50: 863–872
   PubMed Web of Science ®Google Scholar
• Hernandez D., Janmohamed A., Chandan P., Phillips I. R., Shephard E. A. Organization and evolution of the flavin-containing monooxygenase genes of human and mouse: identification of novel gene and pseudogene clusters. Pharmacogenetics 2004; 14: 117–130
   PubMedGoogle Scholar
• Hines R. N. Developmental and tissue-specific expression of human flavin-containing monooxygenase 1 and 3. Expet. Opin. Drug. Metabol. Toxicol. 2006; 2: 41–49
   PubMed Web of Science ®Google Scholar
• Hines R. N., Hopp K. A., Franco J., Saeian K., Begun F. P. Alternative processing of the human hepatic FMO6 gene renders transcripts incapable of encoding a functional flavin-containing monooxygenase. Mol. Pharmacol. 2002; 62: 320–325
   PubMed Web of Science ®Google Scholar
• Hisamuddin I. M., Wehbi M. A., Schmotzer B., Easley K. A., Hylind L. M., Giardiello F. M., Yang V. W. Genetic polymorphisms of flavin monooxygenase 3 in sulindac-induced regression of colorectal adenomas in familial adenomatous polyposis. Canc. Epidemiol. Biomarkers Prev. 2005; 14: 2366–2369
   PubMed Web of Science ®Google Scholar
• Janmohamed A., Hernandez D., Phillips I. R., Shephard E. A. Cell-, tissue-, sex- and developmental stage-specific expression of mouse flavin-containing monooxygenases (Fmos). Biochem. Pharmacol. 2004; 68: 73–83
   PubMed Web of Science ®Google Scholar
• Javahery R., Khachi A., Lo K., Zenzie-Gregory B., Smale S. T. DNA sequence requirements for transcriptional initiator activity in mammalian cells. Mol. Cell. Biol. 1994; 14: 116–127
   PubMed Web of Science ®Google Scholar
• Jover R., Bort R., Gómez-Lechón M. J., Castell J. V. Re-expression of C/EBPα induces CYP2B6, CYP2C9, and CYP2D6 genes in HepG2 cells. FEBS Lett. 1998; 431: 227–230
   PubMed Web of Science ®Google Scholar
• Kel A. E., Gossling E., Reuter I., Cheremushkin E., Kel-Margoulis O. V., Wingender E. MATCH: A tool for searching transcription factor binding sites in DNA sequences. Nucleic Acids Res. 2003; 31: 3576–3579
   PubMed Web of Science ®Google Scholar
• Koukouritaki S. B., Simpson P., Yeung C. K., Rettie A. E., Hines R. N. Human hepatic flavin-containing monooxygenase 1 (FMO1) and 3 (FMO3) developmental expression. Pediatric Res. 2002; 51: 236–243
   PubMed Web of Science ®Google Scholar
• Krueger S. K., Williams D. E. Mammalian flavin-containing monooxygenases: structure/function, genetic polymorphisms, and role in drug metabolism. Pharmacol. Ther. 2005; 106: 357–387
   PubMed Web of Science ®Google Scholar
• Li S., Hunger S. P. The DBP transcriptional activation domain is highly homologous to that of HLF and TEF and is not responsible for the tissue type-specific transcriptional activity of DBP. Gene 2001; 263: 239–245
   PubMed Web of Science ®Google Scholar
• Luo Z., Hines R. N. Identification of multiple flavin-containing monooxygenase form 1 (FMO1) gene promoters and observation of tissue-specific DNaseI hypersensitive sites. Arch. Biochem. Biophys. 1996; 336: 251–260
   PubMed Web of Science ®Google Scholar
• Mantovani R. A survey of 178 NF-Y binding CCAAT boxes. Nucleic Acids Res. 1998; 26: 1135–1143
   PubMed Web of Science ®Google Scholar
• Mantovani R. The molecular biology of the CCAAT-binding factor NF-Y. Gene 1999; 239: 15–27
   PubMed Web of Science ®Google Scholar
• Mantovani R., Li X. Y., Pessara U., Hooft van Huijsduijnen R., Benoist C., Mathis D. Dominant negative analogs of NF-YA. J. Biol. Chem. 1994; 269: 20340–20346
   PubMed Web of Science ®Google Scholar
• Marchenko G. N., Marchenko N. D., Leng J., Strongin A. Y. Promoter characterization of the novel human matrix metalloproteinase-26 gene: regulation by the T-cell factor-4 implies specific expression of the gene in cancer cells of epithelial origin. Biochem. J. 2002; 363: 253–262
   PubMed Web of Science ®Google Scholar
• Matys V., Kel-Margoulis O. V., Fricke E., Liebich I., Land S., Barre-Dirrie A., Reuter I., Chekmenev D., Krull M., Hornischer K., Voss N., Stegmaier P., Lewicki-Potapov B., Saxel H., Kel A. E., Wingender E. TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotes. Nucleic Acids Res. 2006; 34: D108–D110
   PubMed Web of Science ®Google Scholar
• Mendel D. B., Hansen L. P., Graves M. K., Conley P. B., Crabtree G. R. HNF-1 alpha and HNF-1 beta (vHNF-1) share dimerization and homeo domains, but not activation domains, and form heterodimers in vitro. Gene Dev. 1991; 5: 1042–1056
   PubMed Web of Science ®Google Scholar
• Mitchell S. C., Smith R. L. Trimethylaminuria: The fish malodor syndrome. Drug Metab. Dispos. 2001; 29: 517–521
   PubMed Web of Science ®Google Scholar
• Monica K., Galili N., Nourse J., Saltman D., Cleary M. L. PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1. Mol. Cell Biol. 1991; 11: 6149–6157
   PubMed Web of Science ®Google Scholar
• Morgan E. T., Ullrich V., Daiber A., Schmidt P., Takaya N., Shoun H., McGiff J. C., Oyekan A., Hanke C. J., Campbell W. B., Park C. S., Kang J. S., Yi H. G., Cha Y. N., Mansuy D., Boucher J. L. Cytochromes P450 and flavin monooxygenases--targets and sources of nitric oxide. Drug Metab Dispos. 2001; 29: 1366–1376
   PubMed Web of Science ®Google Scholar
• Overby L. H., Carver G. C., Philpot R. M. Quantitation and kinetic properties of hepatic microsomal and recombinant flavin-containing monooxygenases 3 and 5 from humans. Chem. Biol. Interact. 1997; 106: 29–45
   PubMed Web of Science ®Google Scholar
• Popperl H., Bienz M., Studer M., Chan S. K., Aparicio S., Brenner S., Mann R. S., Krumlauf R. Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx. Cell 1995; 81: 1031–1042
   PubMed Web of Science ®Google Scholar
• Remenyi A., Tomilin A., Scholer H. R., Wilmanns M. Differential activity by DNA-induced quarternary structures of POU transcription factors. Biochem. Pharmacol. 2002; 64: 979–984
   PubMed Web of Science ®Google Scholar
• Selleri L., DiMartino J., van Deursen J., Brendolan A., Sanyal M., Boon E., Capellini T., Smith K. S., Rhee J., Popperl H., Grosveld G., Cleary M. L. The TALE homeodomain protein Pbx2 is not essential for development and long-term survival. Mol. Cell Biol. 2004; 24: 5324–5331
   PubMed Web of Science ®Google Scholar
• Shi Y., Seto E., Chang L., Shenk T. Transcriptional repression by YY1, a human GLI-Kruppel-related protein and relief of repression by adenovirus E1A protein. Cell 1991; 67: 377–388
   PubMed Web of Science ®Google Scholar
• Shimada T., Yamazaki H., Mimura M., Inui Y., Guengerich F. P. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens, and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians. J. Pharmacol. Exp. Ther. 1994; 270: 414–423
   PubMed Web of Science ®Google Scholar
• Sirito M., Lin Q., Maity T., Sawadogo M. Ubiquitous expression of the 43- and 44-kDa forms of transcription factor USF in mammalian cells. Nucleic Acids Res. 1994; 22: 427–433
   PubMed Web of Science ®Google Scholar
• Stevens J. C., Shipley L. A., Cashman J. R., Vandenbranden M., Wrighton S. A. Comparison of human and rhesus monkey in vitro phase I and phase II hepatic drug metabolism activities. Drug Metab. Dispos. 1993; 21: 753–760
   PubMed Web of Science ®Google Scholar
• Takahashi Y., Hamada J., Murakawa K., Takada M., Tada M., Nogami I., Hayashi N., Nakamori S., Monden M., Miyamoto M., Katoh H., Moriuchi T. Expression profiles of 39 HOX genes in normal human adult organs and anaplastic thyroid cancer cell lines by quantitative real-time RT-PCR system. Exp. Cell Res. 2004; 293: 144–153
   PubMed Web of Science ®Google Scholar
• Thomas M. J., Seto E. Unlocking the mechanisms of transcription factor YY1: Are chromatin modifying enzymes the key?. Gene 1999; 236: 197–208
   PubMed Web of Science ®Google Scholar
• Tijet N., Boutros P. C., Moffat I. D., Okey A. B., Tuomisto J., Pohjanvirta R. Aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries. Mol. Pharmacol. 2006; 69: 140–153
   PubMed Web of Science ®Google Scholar
• Wilkening S., Stahl F., Bader A. Comparison of primary human hepatocytes and hepatoma cell line HepG2 with regard to their biotransformation properties. Drug Metab Dispos. 2003; 31: 1035–1042
   PubMed Web of Science ®Google Scholar
• Yano M., Falvey E., Gonzalez F. J. Role of the liver-enriched transcription factor DBP in expression of the cytochrome P450 CYP2C6 gene. Mol. Cell. Biol. 1992; 12: 2847–2854
   PubMed Web of Science ®Google Scholar
• Zhang J., Cashman J. R. Quantitative analysis of FMO gene mRNA levels in human tissues. Drug Metab Dispos. 2006; 34: 19–26
   PubMed Web of Science ®Google Scholar
• Ziegler D. M. An overview of the mechanism, substrate specificities, and structure of FMOs. Drug Metab. Rev. 2002; 34: 503–511
   PubMed Web of Science ®Google Scholar