Influence of Polymeric Blend of Carbomer-Gum on the Targeted Delivery of 5-FU

REFERENCES

• Basit , A.W. Advances in colonic drug delivery . Drugs 2005 , 65 , 1991 .
   PubMed Web of Science ®Google Scholar
• Kinget , R. ; Kalale , W. ; Vervoort , L. ; Mooter , G.V. Colonic drug targeting . J. Drug Target. 1998 , 6 , 129 – 149 .
   PubMed Web of Science ®Google Scholar
• Aulton , M.E. Pharmaceutics: The Science of Dosage Form Design, , 2nd Ed. , Churchill Livingstone : New York , pp. 289 – 306 , 2002 .
   Google Scholar
• Follonier , N. ; Doelker , E. Biopharmaceutical comparison of oral multiple-unit and single-unit sustained-release dosage forms . STP Pharm. Sci. 1992 , 2 , 141 – 155 .
   Google Scholar
• Sangalli , M.E. ; Maroni , A.A. ; Foppoli , L. ; Zema , F. ; Giordano , A. ; Gazzaniga , A. Different HPMC viscosity grades as coating agents for an oral time and/or site-controlled delivery system: a study on process parameters and in vitro performances . Eur. J. Pharm. Sci. 2004 , 22 , 469 – 476 .
   PubMed Web of Science ®Google Scholar
• Pullan , R.D. Transdermal nicotine for active ulcerative colitis . N. Engl. J. Med. 1993 , 330 , 811 – 815 .
   Google Scholar
• Sandborn , W.J. ; Rhodes , J. Colonic delivery of nicotine to treat inflammatory bowel disease . U.S. Patent 5846983 , 1996 .
   Google Scholar
• Brock , M.H. Use of in vitro and in vivo data in the Design, development, and quality control of sustained-release decongestant dosage forms . Pharmacotherapy 1994 , 14 , 430 – 437 .
   PubMed Web of Science ®Google Scholar
• Sinha , V.R. ; Rachna , K. Polysaccharides in colon-specific drug delivery . Int. J. Pharm. 2004 , 224 , 19 – 38 .
   Google Scholar
• Beretta , G.D. ; Milesi , L. ; Pessi , M.A. ; Mosconi , S. ; Labianca , R. Adjuvant treatment of colorectal cancer . Surg. Oncol. 2004 , 13 , 63 – 73 .
   PubMedGoogle Scholar
• Ciftci , K. ; Groves , M.J. Delivery of antitumor compounds to the rat colon: In vitro and in vivo evaluation . Int. J. Pharm. 1996 , 145 , 157 – 164 .
   Web of Science ®Google Scholar
• Goto , T. ; Tomizawa , N. ; Kobayashi , F. ; Fujimura , A. A comparative pharmacology study between the intracolonic and oral routes of 5-FU administration in a colon cancer-bearing Yoshida sarcoma rat model . J. Pharmacol. Sci. 2004 , 95 , 163 – 173 .
   PubMed Web of Science ®Google Scholar
• United States Pharmacopoeia, 27th Edn. 2004. United States Pharmacopoeial Convention Inc., Twin Brook Pathway. Rockville, MD 20852 .
   Google Scholar
• Sinha , V.R. ; Mittal , B.R. ; Bhutani , K.K. ; Kumari , R. Colonic drug delivery of 5-Fluorouracil: An in-vitro evaluation . Int. J. Pharm. 2004 , 269 , 101 – 108 .
   PubMed Web of Science ®Google Scholar
• Higuchi , T. Rate of release of medications from ointment bases containing drugs in suspension . J. Pharm. Sci. 1961 , 50 , 874 – 875 .
   PubMed Web of Science ®Google Scholar
• Korsemeyer , R.W. ; Gurny , R. ; Doelker , E. ; Buri , P. ; Peppas , N.A. Mechanisms of potasssiun chloride release from compressed, hydrophilic, polymeric matrices: Effect of entrapped air . J. Pharm. Sci. 1983 , 72 , 1189 – 1191 .
   PubMedGoogle Scholar
• Hixon , A.W. ; Crowell , J.H. Dependence of reaction velocity upon surface and agitation . Ind. Eng. Chem. 1931 , 23 , 923 – 931 .
   Google Scholar
• Scott , R.A. ; Cole , E.T. Enteric and colonic delivery using HPMC capsules . U.S. Patent 7094725 , 2006 .
   Google Scholar
• Siepmann , J. ; Kranz , H. ; Bodmeier , R. A new model combining diffusion, swelling, and dissolution mechanisms and predicting the release kinetics . Pharm Res. 1999 , 16 , 1748 – 1756 .
   PubMed Web of Science ®Google Scholar
• Kibbe , A.H. Handbook of Pharmaceutical Excipients, , 3rd Ed. Pharmaceutical Press, United Kingdom . 2000 , 79 – 82 .
   Google Scholar
• Ishibashi , T. ; Hatano , H. ; Kobayashi , M. ; Mizone , M. ; Yoshino , M. Design and evaluation of a new capsule-type dosage form for colon-targeted delivery of drugs . Int. J. Pharm. 1998 , 168 , 31 – 40 .
   Web of Science ®Google Scholar