Statistical Properties of a Modified Accelerated Design for Phase I Cancer Clinical Trials

References

• Ahn , C. ( 1998 ). An evaluation of phase I cancer clinical trial designs . Statist. Med. 17 : 1537 – 1549 .
   PubMed Web of Science ®Google Scholar
• Babb , J. , Rogatko , A. , Zacks , S. ( 1998 ). Cancer phase I clinical trials: efficient dose escalation with overdose control . Statist. Med. 17 : 1103 – 1120 .
   PubMed Web of Science ®Google Scholar
• Durham , S. , Flournoy , N. , Rosenberger , W. ( 1997 ). A random walk rule for phase I clinical trials . Biometrics 53 : 745 – 760 .
   PubMed Web of Science ®Google Scholar
• Edler , L. ( 2001 ). Overview of phase I trials . In: Crowley , ed. Handbook of Statistics in Clinical Oncology . Marcel Dekker .
   Google Scholar
• Green , S. , Benedetti , J. , Crowley , J. ( 2003 ). Clinical Trials in Oncology . London : Chapman & Hall/CRC .
   Google Scholar
• He , W. , Liu , J. , Binkowitz , B. , Quan , H. ( 2006 ). A model-based approach in the estimation of the maximum tolerated dose in phase I cancer clinical trials . Statist. Med. 25 : 2027 – 2042 .
   PubMedGoogle Scholar
• Korn , E. , Midthune , D. , Chen , T. , Rubinstein , L. , Christian , M. , Simon , A. (1994). A comparison of two phase I trial designs. Statist. Med. 13:1799–1806.
   PubMed Web of Science ®Google Scholar
• Lin , Y. , Shih , W. J. ( 2001 ). Statistical properties of the traditional algorithm-based designs for phase I cancer clinical trials . Biostatistics 2 ( 2 ): 203 – 215 .
   PubMedGoogle Scholar
• O'Quigley , J. , Pepe , M. , Fisher , L. ( 1990 ). Continual reassessment method: a practical design for phase I clinical studies in cancer . Biometrics 46 : 33 – 48 .
   PubMed Web of Science ®Google Scholar
• Rosenberger , W. , Haines , L. ( 2002 ). Competing designs for phase I clinical trials: a review . Statist. Med. 21 : 2757 – 2770 .
   PubMed Web of Science ®Google Scholar
• Simon , R. , Freidlin , B. , Rubinstein , L. , et al. . ( 1997 ). Accelerated titration designs for phase I clinical trials in oncology . J. Nat. Cancer Instit. 89 ( 15 ): 1138 – 1147 .
   PubMed Web of Science ®Google Scholar
• Smith , T. , Lee , J. , Kantarjian , H. , Legha , S. , Rober , M. ( 1996 ). Design and results of phase I cancer clinical trials: three-year experience at M.D. Anderson cancer center . J. Clin. Oncol. 14 ( 1 ): 287 – 295 .
   PubMed Web of Science ®Google Scholar
• Storer , B. ( 1989 ). Design and analysis of phase I clinical trials . Biometrics 45 : 925 – 937 .
   PubMed Web of Science ®Google Scholar
• Whitehead , J. ( 1997 ). Bayesian decision procedures with application to dose-finding studies . Int. J. Pharmaceut. Med. 11 : 201 – 208 .
   Google Scholar
• Whitehead , J. , Brunier , H. ( 1995 ). Bayesian decision procedures for dose determining experiments . Statist. Med. 14 : 885 – 893 .
   PubMed Web of Science ®Google Scholar