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Research Article

Lactobacillus rhamnosus has no beneficial effect on anthropometric parameters, carbohydrate metabolism and androgen status in women with polycystic ovary syndrome

, PhDORCID Icon & , PhD
Pages 336-347 | Received 24 Sep 2021, Accepted 25 Apr 2022, Published online: 03 May 2022

References

  • Ahmadi, S., M. Jamilian, M. Karamali, M. Tajabadi-Ebrahimi, P. Jafari, and M. Taghizadeh. 2017. Probiotic supplementation and the effects on weight loss, glycaemia and lipid profiles in women with polycystic ovary syndrome: A randomized, double - blind, placebo - controlled trial. Human Fertility 20:254–61. doi:10.1080/14647273.2017.1283446.
  • Araszkiewicz, A., E. Bandurska-Stankiewicz, A. Budzyński, K. Cypryk, A. Czech, L. Czupryniak, J. Drzewoski, G. Dzida, T. Dziedzic, E. Franek, et al. 2020. Guidelines on the management of diabetic patients a position of diabetes Poland. Clinical Diabetology 9:1–110.
  • Asuncion, M., R. M. Calvo, J. M. San Millan, J. Sancho, S. Avila, and H. F. Escobar-Morreale. 2000. A prospective study of the prevalence of the polycystic ovary syndrome in unselected Caucasian women from Spain. Journal of Clinical Endocrinology & Metabolism 85 (7):2434–38. doi:10.1210/jcem.85.7.6682.
  • Avignon, A., C. Boegner, D. Mariano-Goulart, C. Colette, and L. Monnier. 1999. Assessment of insulin sensitivity from plasma insulin and glucose in the fasting or post oral glucose-load state. International Journal of Obesity and Related Metabolic Disorders 23 (5):512–17. doi:10.1038/sj.ijo.0800864.
  • Barber, T. M., P. Hanson, M. O. Weickert, and S. Franks. 2019. Obesity and polycystic ovary syndrome: Implications for pathogenesis and novel management strategies. Clinical Medicine Insights: Reproductive Health 13:1179558119874042. doi:10.1177/1179558119874042.
  • Bastard, J. P., J. M. Vandernotte, M. Faraj, A. D. Karelis, L. Messier, F. M. Malita, D. R. Garrel, D. Prud’homme, and R. Rabasa-Lhoret. 2007. Relationship between the hyperinsulinemic-euglycaemic clamp and a new simple index assessing insulin sensitivity in overweight and obese postmenopausal women. Diabetes & Metabolism 33 (4):261–68. doi:10.1016/j.diabet.2007.02.004.
  • Cerdo, T., J. A. Garcia-Santos, M. G. Bermudez, C. Campoy, and M. 2019. The role of probiotics and prebiotics in the prevention and treatment of obesity. Nutrients 11 (3):635. doi:10.3390/nu11030635.
  • Crovesy, L., M. Ostrowski, D. M. T. P. Ferreira, E. L. Rosado, and M. Soares-Mota. 2017. Effect of Lactobacillus on body weight and body fat in overweight subjects: A systematic review of randomized controlled clinical trials. International Journal of Obesity 41 (11):1607–14. doi:10.1038/ijo.2017.161.
  • Dall’-Ogliom, F., M. Milani, and G. Micali. 2018. Effects of oral supplementation with FOS and GOS prebiotics in women with adult acne: The “S.O. Sweet” study: A proof-of-concept pilot trial. Clinical, Cosmetic and Investigational Dermatology 11:445–49. doi:10.2147/CCID.S179627.
  • Erejuwa, O. O., S. A. Sulaiman, and M. S. A. Wahab. 2014. Modulation of gut microbiota in the management of metabolic disorders: The prospects and challenges. International Journal of Molecular Sciences 15 (3):4158–88. doi:10.3390/ijms15034158.
  • Esmaeilinezhad, Z., S. Babajafari, Z. Sohrabi, M.-H. Eskandari, S. Amooee, and R. Barati-Boldaji. 2019. Effect of synbiotic pomegranate juice on glycemic, sex hormone profile and anthropometric indices in PCOS: A randomized, triple blind, controlled trial. Nutrition, Metabolism and Cardiovascular Disease 29 (2):201–08. doi:10.1016/j.numecd.2018.07.002.
  • Ganesan, K., S. K. Chung, J. Vanamala, and B. Xu. 2018. Causal relationship between diet-induced gut microbiota changes and diabetes: A novel strategy to transplant Faecalibacterium prausnitzii in preventing diabetes. International Journal of Molecular Sciences 19 (12):3720. doi:10.3390/ijms19123720.
  • Gonzalez, F., C. L. Sia, M. K. Shepard, N. S. Rote, and J. Minium. 2012. Hyperglycemia induced oxidative stress is independent of excess abdominal adiposity in normal-weight women with polycystic ovary syndrome. Human Reproduction 27 (12):3560–68. doi:10.1093/humrep/des320.
  • He, F., and Y. Li. 2020. Role of gut microbiota in the development of insulin resistance and the mechanism underlying polycystic ovary syndrome: A review. Journal of Ovarian Research 13:73. doi:10.1186/s13048-020-00670-3.
  • Hulston, C. J., A. A. Churnside, and M. C. Venables. 2015. Probiotic supplementation prevents high-fat, overfeeding-induced insulin resistance in human subjects. British Journal of Nutrition 113 (4): 596–02. doi:10.1017/S0007114514004097.
  • Jamilian, M., S. Mansury, F. Bahmani, Z. Heidar, E. Amirani, and Z. Asemi. 2018. The effects of probiotic and selenium co-supplementation on parameters of mental health, hormonal profiles, and biomarkers of inflammation and oxidative stress in women with polycystic ovary syndrome. Journal of Ovarian Research 11 (1):80. doi:10.1186/s13048-018-0457-1.
  • Jarosz, M., E. Rychlik, K. Stoś, and J. Charzewska. 2020. Normy żywienia dla populacji Polski i ich zastosowanie. Warsaw: NPZ -PZH.
  • Kang, Y., and Y. Cai. 2018. The development of probiotics therapy to obesity: A therapy that has gained considerable momentum. Hormones (Athens) 17 (2):141–51. doi:10.1007/s42000-018-0003-y.
  • Karamali, M., S. Eghbalpour, S. Rajabi, M. Jamilian, F. Bahmani, and M. Tajabadi-Ebrahimi. 2018. Effects of probiotic supplementation on hormonal profiles, biomarkers of inflammation and oxidative stress in women with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled trial. Archives of Iranian Medicine 21 (1):1–7.
  • Karimi, M., J. Heshmati, N. Shirzad, S. Vesali, M. Javad Hosseinzadeh-Attar, A. Moini, and M. Sepidarkish. 2020. The effect of synbiotics supplementation on anthropometric indicators and lipid profiles in women with polycystic ovary syndrome: A randomized controlled trial. Lipids in Health and Disease 19:60. doi:10.1186/s12944-020-01244-4.
  • Katz, A., S. S. Nambi, K. Mather, A. D. Baron, D. A. Follmann, G. Sullivan, and M. J. Quon. 2000. Quantitative insulin sensitivity check index: A simple, accurate method for assessing insulin sensitivity in humans. Journal of Clinical Endocrinology & Metabolism 85 (7):2402–10. doi:10.1210/jcem.85.7.6661.
  • Łagowska, K., and K. Kapczuk. 2021. Effects of nutritional intervention with or without metformin on insulin resistance in adolescents with polycystic ovary syndrome: A preliminary study. Progress in Nutrition 23:e2021015. doi:10.23751/pn.v23i1.9163.
  • Łagowska, K., and S. Drzymała-Czyż. 2022. A low glycemic index, energy-restricted diet but not Lactobacillus rhamnosus supplementation changes fecal short-chain fatty acid and serum lipid concentrations in women with overweight or obesity and polycystic ovary syndrome. European Review for Medical and Pharmacology Sciences 26:917–26. doi:10.26355/eurrev_202202_28001.
  • Legro, R. S. 2000. The genetics of obesity. Lessons for polycystic ovary syndrome. Annals of the New York Academy Sciences 900. 193-02. doi:10.1111/j.1749-6632.2000.tb06230.x.
  • Legro, R. S., H. X. Barnhart, W. D. Schlaff, B. R. Carr, M. P. Diamond, S. A. Carson, M. P. Steinkampf, C. Coutifaris, P. G. McGovern, N. A. Cataldo, et al. 2007. Clomiphene, metformin, or both for infertility in the polycystic ovary syndrome. The New England Journal of Medicine 6:551–56. doi:10.1056/NEJMoa063971.
  • Liao, D., C. Zhong, C. Li, L. Mo, and Y. Liu. 2018. Meta-analysis of the effects of probiotic supplementation on glycemia, lipidos profiles, weight loss and C-reactive protein in women with polycystic ovarian syndrome. Minerva Medica 109 (6):479–87. doi:10.23736/S0026-4806.18.05728-2.
  • Lim, S. S., S. K. Hutchison, E. Van Ryswyk, R. J. Norman, H. J. Teede, and L. J. Moran. 2019. Lifestyle changes in women with polycystic ovary syndrome. Cochrane Database of Systematic Reviews 3 (3):CD007506. doi:10.1002/14651858.CD007506.pub4.
  • Markowiak, P., and K. Śliżewska. 2017. Effects of probiotics, prebiotics, and synbiotics on human health. Nutrients 9 (9):1021. doi:10.3390/nu9091021.
  • Martinez, K. B., J. F. Pierre, and E. B. Chang. 2016. The gut microbiota: The gateway to improved metabolism. Gastroenterology Clinics of North America 45 (4):601–14. doi:10.1016/j.gtc.2016.07.001.
  • Matthews, D. R., J. P. Hosker, A. S. Rudenski, B. A. Naylor, D. F. Treacher, and R. C. Turner. 1985. Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28 (7):412–19. doi:10.1007/BF00280883.
  • Mohammadi, H., A. Ghavami, A. Hadi, G. Askari, M. Symonds, and M. Miraghajani. 2019. Effects of pro-/synbiotic supplementation on anthropometric and metabolic indices in overweight or obese children and adolescents: A systematic review and meta-analysis. Complementary Therapies in Medicine 44:269–76. doi:10.1016/j.ctim.2019.05.008.
  • Moran, L., and R. J. Norman. 2004. Understanding and managing disturbances in insulin metabolism and body weight in women with polycystic ovary syndrome. Best Practice & Research Clinical Obstetrics & Gynaecology 18 (5):719–36. doi:10.1016/j.bpobgyn.2004.05.003.
  • Moran, L. J., E. C. Tassone, J. Boyle, L. Brennan, C. L. Harrison, A. L. Hirschberg, S. Lim, K. Marsh, M. L. Misso, L. Redman, et al. 2020. Evidence summaries and recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome: Lifestyle management. Obesity Reviews 21 (10):e13046. doi:10.1111/obr.13046.
  • Nasri, K., M. Jamilian, E. Rahmani, F. Bahmani, M. Tajabadi-Ebrahimi, and Z. Asemi. 2018. The effects of synbiotic supplementation on hormonal status, biomarkers of inflammation and oxidative stress in subjects with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled trial. BMC Endocrine Disorders 18 (1):21. doi:10.1186/s12902-018-0248-0.
  • Nestler, J. E. 2016. Polycystic ovary syndrome. The New England: Journal of Medicine 375 (14):1398. doi:10.1056/NEJMc1610000.
  • Ostadmohammadi, V., M. Jamilian, F. Bahmani, and Z. Asemi. 2019. Vitamin D and probiotic co-supplementation affects mental health, hormonal, inflammatory and oxidative stress parameters in women with polycystic ovary syndrome. Journal of Ovarian Research 12:5. doi:10.1186/s13048-019-0480-x.
  • Pan, C., Y. Zhao, S. F. Liao, F. Chen, S. Qin, X. Wu, H. Zhou, and K. Huang. 2011. Effect of selenium enriched probiotics on laying performance, egg quality, egg selenium content, and egg glutathione peroxidase activity. Journal of Agricultural and Food Chemistry 59:11424–31. doi:10.1021/jf202014k.
  • Phillips, P. J. 2012. Oral glucose tolerance testing. Australian Family Physician 41 (6):391–93.
  • Rotterdam ESHRE. 2004. ASRM-Sponsored PCOS consensus workshop group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertility and Sterility 81: 19–25. 10.1016/j.fertnstert.2003.10.004
  • Samimi, M., A. Dadkhah, H. H. Kashani, M. Tajabadi-Ebrahimi, E. S. Hosseini, and Z. Asemi. 2018. The effect of the synbiotic supplementation on metabolic status in women with polycystic ovary syndrome: A randomized double-blind clinical trial. Probiotics and Antimicrobial Proteins 11 (4):1355–61. doi:10.1007/s12602-018-9405-z.
  • Sanchez, M., C. Darimont, V. Drapeau, S. Emady-Azar, M. Lepage, E. Rezzonico, C. Ngom-Bru, B. Berger, L. Philippe, C. Ammon-Zuffrey, et al. 2014. Effect of Lactobacillus rhamnosus CGMCC1.3724 supplementation on weight loss and maintenance in obese men and women. British Journal of Nutrition 111 (08):1507–19. doi:10.1017/S0007114513003875.
  • Shabani, A., M. Noshadian, M. Jamilian, M. Chamani, S. Mohammadi, and Z. Asemi. 2018. The effects of a novel combination of selenium and probiotic on weight loss, glycemic control and markers of cardio-metabolic risk in women with polycystic ovary syndrome. Journal of Functional Food 46:329–34. doi:10.1016/j.jff.2018.04.071.
  • Shoaei, T., M. Heidari-Beni, and H. G. Tehrani. 2015. Effects of probiotic supplementation on pancreatic b-cell function and c-reactive protein in women with polycystic ovary syndrome: A randomized double blind placebo-controlled clinical trial. International Journal of Preventive Medicine 6:27. doi:10.4103/2008-7802.153866.
  • Song, J., X. Ruan, M. Gu, L. Wang, H. Wang, and A. O. Mueck. 2018. Effect of orlistat or metformin in overweight and obese polycystic ovary syndrome patients with insulin resistance. Gynecological Endocrinology 34:413–17. doi:10.1080/09513590.2017.1407752.
  • Stumvoll, M., A. Mitrakou, W. Pimenta, T. Jenssen, H. Yki-Järvinen, T. Van Haeften, W. Renn, and J. Gerich. 2000. Use of the oral glucose tolerance test to assess insulin release and insulin sensitivity. Diabetes Care 23. 295–01. doi:10.2337/diacare.23.3.295.
  • Tabrizi, R., V. Ostadmohammadi, M. Akbari, K. B. Lankarani, S. Vakili, and P. Peymani. 2019. The effects of probiotic supplementation on clinical symptom, weight loss, glycemic control, lipid and hormonal profiles, biomarkers of inflammation, and oxidative stress in women with polycystic ovary syndrome: A systematic review and meta-analysis of randomized controlled trials. Probiotics Antimicrobial Proteins 14 (1):1–14. doi:10.1007/s12602-019-09559-0.
  • Torres, P. J., B. S. Ho, P. Arroyo, L. Sau, A. Chen, S. T. Kelley, and V. G. Thackray. 2019. Exposure to a healthy gut microbiome protects against reproductive and metabolic dysregulation in a PCOS mouse model. Endocrinology 160 (5):1193–204. doi:10.1210/en.2019-00050.
  • Tremellen, K., and K. Pearce. 2012. Dysbiosis of gut microbiota (DOGMA) – A novel theory for the development of polycystic ovarian syndrome. Medical Hypotheses 79 (1):104–12. doi:10.1016/j.mehy.2012.04.016.
  • Zeng, B., Z. Lai, L. Sun, Z. Zhang, J. Yang, Z. Li, J. Lin, and Z. Zhang. 2019. Structural and functional profiles of the gut microbial community in polycystic ovary syndrome with insulin resistance (IR-PCOS): A pilot study. Research in Microbiology 170 (1):43–52. doi:10.1016/j.resmic.2018.09.002.
  • Zhuang, J., X. Wang, L. Xu, T. Wu, and D. Kang. 2013. Antidepressants for Polycystic Ovary Syndrome. Cochrane Database Systematic Review 2013 (5): CD008575. 10.1002/14651858.CD008575.pub2.

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