233
Views
2
CrossRef citations to date
0
Altmetric
Research Article

Inflammatory biomarkers and lipid metabolism parameters in women with mild cognitive impairment and dementia

, PhDORCID Icon, ORCID Icon, , PhDORCID Icon, , PhDORCID Icon, ORCID Icon, , PhDORCID Icon, ORCID Icon, ORCID Icon, , PhDORCID Icon, , PhDORCID Icon, , PhDORCID Icon, , PhDORCID Icon, , PhDORCID Icon, , PhDORCID Icon & , PhDORCID Icon show all
Pages 285-295 | Received 23 Apr 2022, Accepted 20 Feb 2023, Published online: 07 Mar 2023

References

  • Alvarez, X. A., I. Alvarez, M. Aleixandre, C. Linares, D. Muresanu, S. Winter, and H. Moessler. 2018. Severity-related increase and cognitive correlates of serum VEGF levels in Alzheimer’s disease ApoE4 carriers. Journal of Alzheimer’s Disease 63 (3):1003–13. doi:10.3233/JAD-160477.
  • Amin, J., D. Erskine, P. C. Donaghy, A. Surendranathan, P. Swann, A. P. Kunicki, D. Boche, C. Holmes, I. G. McKeith, J. T. O’brien, et al. 2022. Inflammation in dementia with Lewy bodies. Neurobiology of Disease 168:105698. doi:10.1016/j.nbd.2022.105698.
  • Anstey, K. J., K. Ashby-Mitchell, and R. Peters. 2017. Updating the evidence on the association between serum cholesterol and risk of late-life dementia: Review and meta-analysis. Journal of Alzheimer’s Disease 56 (1):215–28. doi:10.3233/JAD-160826.
  • Armstrong, R. A. 2013. What causes Alzheimer’s disease? Folia Neuropathological 51 (3):169–88. doi:10.5114/fn.2013.37702.
  • Björkqvist, M., M. Ohlsson, L. Minthon, and O. Hansson. 2012. Evaluation of a previously suggested plasma biomarker panel to identify Alzheimer’s disease. PLoS One 7 (1):e29868. doi:10.1371/journal.pone.0029868.
  • Brosseron, F., M. Krauthausen, M. Kummer, and M. T. Heneka. 2014. Body fluid cytokine levels in mild cognitive impairment and Alzheimer’s disease: A comparative overview. Molecular Neurobiology 50 (2):534–44. doi:10.1007/s12035-014-8657-1.
  • Buchhave, P., H. Zetterberg, K. Blennow, L. Minthon, S. Janciauskiene, and O. Hansson. 2010. Soluble TNF receptors are associated with Aβ metabolism and conversion to dementia in subjects with mild cognitive impairment. Neurobiology of Aging 31 (11):1877–84. doi:10.1016/j.neurobiolaging.2008.10.012.
  • Creavin, S. T., S. Wisniewski, A. H. Noel-Storr, C. M. Trevelyan, T. Hampton, D. Rayment, V. M. Thom, K. J. Nash, H. Elhamoui, R. Milligan, et al. 2016. Mini-Mental State Examination (MMSE) for the detection of dementia in clinically unevaluated people aged 65 and over in community and primary care populations. Cochrane Database of Systematic Reviews 1:CD011145. doi:10.1002/14651858.CD011145.pub2.
  • da Rocha, J. F., L. Bastos, S. C. Domingues, A. R. Bento, U. Konietzko, O. da Cruz E Silva, and S. I. Vieira. 2021. APP binds to the EGFR ligands HB-EGF and EGF, acting synergistically with EGF to promote ERK signaling and neuritogenesis. Molecular Neurobiology 58 (2):668–88. doi:10.1007/s12035-020-02139-2.
  • de Leeuw, F. A., W. M. van der Flier, B. M. Tijms, P. Scheltens, V. M. Mendes, B. Manadas, J. Bierau, N. van Wijk, E. van den Heuvel, M. H. Mohajeri, et al. 2020. Specific nutritional biomarker profiles in mild cognitive impairment and subjective cognitive decline are associated with clinical progression: The NUDAD project. Journal of the American Medical Directors Association 21 (10):1513.e1–1513.e17. doi:10.1016/j.jamda.2019.12.009.
  • Derreberry, T. M., and S. Holroyd. 2019. Dementia in women. The Medical Clinics of North America 103 (4):713–21. doi:10.1016/j.mcna.2019.02.004.
  • Desideri, G., F. Cipollone, S. Necozione, C. Marini, M. C. Lechiara, G. Taglieri, G. Zuliani, R. Fellin, A. Mezzetti, F. di Orio, et al. 2008. Enhanced soluble CD40 ligand and Alzheimer’s disease: Evidence of a possible pathogenetic role. Neurobiology of Aging 29 (3):348–56. doi:10.1016/j.neurobiolaging.2006.10.019.
  • Erol, R., D. Brooker, and E. Peel. 2015. Women and dementia: A global research review. London: Alzheimer’s Disease International. Accessed January 11, 2023. http://www.alz.co.uk/women-and-dementia.
  • Erol, R., D. Brooker, and E. Peel. 2016. The impact of dementia on women internationally: An integrative review. Health Care for Women International 37 (12):1320–41. doi:10.1080/07399332.2016.1219357.
  • Friedewald, W. T., R. I. Levy, and D. S. Fredrickson. 1972. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clinical Chemistry 18 (6):499–502. doi:10.1093/clinchem/18.6.499.
  • Giunta, B., K. Rezai-Zadeh, and J. Tan. 2010. Impact of the CD40-CD40L dyad in Alzheimer’s disease. CNS & Neurological Disorders Drug Targets 9 (2):149–55. doi:10.2174/187152710791012099.
  • He, Q., Q. Li, J. Zhao, T. Wu, L. Ji, G. Huang, and F. Ma. 2016. Relationship between plasma lipids and mild cognitive impairment in the elderly Chinese: A case-control study. Lipids in Health and Disease 15 (1):146. doi:10.1186/s12944-016-0320-6.
  • Heneka, M. T., M. J. Carson, J. El Khoury, G. E. Landreth, F. Brosseron, D. L. Feinstein, A. H. Jacobs, T. Wyss-Coray, J. Vitorica, R. M. Ransohoff, et al. 2015. Neuroinflammation in Alzheimer’s disease. Lancet Neurology 14 (4):388–405. doi:10.1016/S1474-4422(15)70016-5.
  • Ivanovska, M., Z. Abdi, M. Murdjeva, D. Macedo, A. Maes, and M. Maes. 2020. CCL-11 or eotaxin-1: An immune marker for ageing and accelerated ageing in neuro-psychiatric disorders. Pharmaceuticals (Basel, Switzerland) 13 (9):230. doi:10.3390/ph13090230.
  • Kao, Y. C., P. C. Ho, Y. K. Tu, I. M. Jou, and K. J. Tsai. 2020. Lipids and Alzheimer’s disease. International Journal of Molecular Sciences 21 (4):1505. doi:10.3390/ijms21041505.
  • Karch, C. M., C. Cruchaga, and A. M. Goate. 2014. Alzheimer’s disease genetics: From the bench to the clinic. Neuron 83 (1):11–26. doi:10.1016/j.neuron.2014.05.041.
  • Kurmyshev, M. V., S. A. Zozulya, N. V. Zakharova, A. N. Barkhatova, I. Y. Nikiforova, and T. P. Klyushnik. 2022. Markers of systemic inflammation in assessing the effectiveness of neurocognitive rehabilitation in aged patients with mild cognitive impairment. Psikhiatriya 20 (3):47–56. doi:10.30629/2618-6667-2022-20-3-47-56.
  • Lai, K., C. S. Liu, A. Rau, K. L. Lanctôt, C. A. Köhler, M. Pakosh, A. F. Carvalho, and N. Herrmann. 2017. Peripheral inflammatory markers in Alzheimer’s disease: A systematic review and meta-analysis of 175 studies. Journal of Neurology, Neurosurgery, and Psychiatry 88 (10):876–82. doi:10.1136/jnnp-2017-316201.
  • Lam, V., R. Takechi, M. M. Pallebage-Gamarallage, S. Galloway, and J. C. Mamo. 2011. Colocalisation of plasma derived apo B lipoproteins with cerebral proteoglycans in a transgenic-amyloid model of Alzheimer’s disease. Neuroscience Letters 492 (3):160–64. doi:10.1016/j.neulet.2011.02.001.
  • Lim, N. S., C. R. Swanson, H. R. Cherng, T. L. Unger, S. X. Xie, D. Weintraub, K. Marek, M. B. Stern, A. Siderowf, J. Q. Trojanowski, et al. 2016. Plasma EGF and cognitive decline in Parkinson’s disease and Alzheimer’s disease. Annals of Clinical and Translational Neurology 3 (5):346–55. doi:10.1002/acn3.299.
  • Liu, C., G. Cui, M. Zhu, X. Kang, and H. Guo. 2014. Neuroinflammation in Alzheimer’s disease: Chemokines produced by astrocytes and chemokine receptors. International Journal of Clinical and Experimental Pathology 7 (12):8342–55.
  • Liu, C., A. Liu, and S. Halabi. 2011. A min-max combination of biomarkers to improve diagnostic accuracy. Statistics in Medicine 30 (16):2005–14. doi:10.1002/sim.4238.
  • Liu, Y., X. Zhong, J. Shen, L. Jiao, J. Tong, W. Zhao, K. Du, S. Gong, M. Liu, and M. Wei. 2020. Elevated serum TC and LDL-C levels in Alzheimer’s disease and mild cognitive impairment: A meta-analysis study. Brain Research 1727:146554. doi:10.1016/j.brainres.2019.146554.
  • Loving, B. A., and K. D. Bruce. 2020. Lipid and lipoprotein metabolism in microglia. Frontiers in Physiology 11:393. doi:10.3389/fphys.2020.00393.
  • Meisner, A., C. R. Parikh, and K. F. Kerr. 2019. Biomarker combinations for diagnosis and prognosis in multicenter studies: Principles and methods. Statistical Methods in Medical Research 28 (4):969–85. doi:10.1177/0962280217740392.
  • Mendes-Santos, L. C., D. Mograbi, B. Spenciere, and H. Charchat-Fichman. 2015. Specific algorithm method of scoring the clock drawing test applied in cognitively normal elderly. Dementia & neuropsychologia 9 (2):128–35. doi:10.1590/1980-57642015DN92000007.
  • Minter, M. R., J. M. Taylor, and P. J. Crack. 2016. The contribution of neuroinflammation to amyloid toxicity in Alzheimer’s disease. Journal of Neurochemistry 136 (3):457–74. doi:10.1111/jnc.13411.
  • Morgan, A. R., S. Touchard, C. Leckey, C. O’hagan, A. J. Nevado-Holgado, NIMA Consortium, F. Barkhof, L. Bertram, O. Blin, I. Bos, et al. 2019. Inflammatory biomarkers in Alzheimer’s disease plasma. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association 15(6):776–87. doi:10.1016/j.jalz.2019.03.007.
  • Morozova, A., Y. Zorkina, K. Pavlov, O. Pavlova, O. Abramova, V. Ushakova, A. V. Mudrak, S. Zozulya, I. Otman, Z. Sarmanova, et al. 2021. Associations of genetic polymorphisms and neuroimmune markers with some parameters of frontal lobe dysfunction in schizophrenia. Frontiers in Psychiatry 12:655178. doi:10.3389/fpsyt.2021.655178.
  • Mukhara, D., U. Oh, and G. N. Neigh. 2020. Neuroinflammation. Handbook of Clinical Neurology 175:235–59. doi:10.1016/B978-0-444-64123-6.00017-5.
  • Nasreddine, Z. S., N. A. Phillips, V. Bédirian, S. Charbonneau, V. Whitehead, I. Collin, J. L. Cummings, and H. Chertkow. 2005. The montreal cognitive assessment, MoCA: A brief screening tool for mild cognitive impairment. Journal of the American Geriatrics Society 53 (4):695–99. doi:10.1111/j.1532-5415.2005.53221.x.
  • Nebel, R. A., N. T. Aggarwal, L. L. Barnes, A. Gallagher, J. M. Goldstein, K. Kantarci, M. P. Mallampalli, E. C. Mormino, L. Scott, W. H. Yu, et al. 2018. Understanding the impact of sex and gender in Alzheimer’s disease: A call to action. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association 14 (9):1171–83. doi:10.1016/j.jalz.2018.04.008.
  • Ohtani, R., S. Nirengi, M. Nakamura, N. Murase, M. Sainouchi, Y. Kuwata, M. Takata, Y. Masuda, K. Kotani, and N. Sakane. 2018. High-density lipoprotein subclasses and mild cognitive Impairment: Study of outcome and aPolipoproteins in dementia (STOP-dementia). Journal of Alzheimer’s Disease 66 (1):289–96. doi:10.3233/JAD-180135.
  • Park, J. C., S. H. Han, and I. Mook-Jung. 2020. Peripheral inflammatory biomarkers in Alzheimer’s disease: A brief review. BMB Reports 53 (1):10–19. doi:10.5483/BMBRep.2020.53.1.309.
  • Petersen, R. C. 2016. Mild Cognitive Impairment. Continuum (Minneapolis, Minn) 22 (2 Dementia):404–18. doi:10.1212/CON.0000000000000313.
  • Pinto, T., L. Machado, T. M. Bulgacov, A. L. Rodrigues-Júnior, M. Costa, R. Ximenes, and E. B. Sougey. 2019. Is the Montreal Cognitive Assessment (MoCA) screening superior to the Mini-Mental State Examination (MMSE) in the detection of mild cognitive impairment (MCI) and Alzheimer’s Disease (AD) in the elderly? International Psychogeriatrics 31 (4):491–504. doi:10.1017/S1041610218001370.
  • Sanford, A. M. 2017. Mild cognitive impairment. Clinics in Geriatric Medicine 33 (3):325–37. doi:10.1016/j.cger.2017.02.005.
  • Scheyer, O., A. Rahman, H. Hristov, C. Berkowitz, R. S. Isaacson, R. Diaz Brinton, and L. Mosconi. 2018. Female sex and Alzheimer’s risk:The menopause connection. The Journal of Prevention of Alzheimer’s Disease 5 (4):225–30. doi:10.14283/jpad.2018.34.
  • Shen, X. N., Y. Lu, C. Tan, L. Y. Liu, J. T. Yu, L. Feng, and A. Larbi. 2019. Identification of inflammatory and vascular markers associated with mild cognitive impairment. Aging 11 (8):2403–19. doi:10.18632/aging.101924.
  • Svensson, T., N. Sawada, M. Mimura, S. Nozaki, R. Shikimoto, and S. Tsugane. 2019. The association between midlife serum high-density lipoprotein and mild cognitive impairment and dementia after 19 years of follow-up. Translational Psychiatry 9 (1):26. doi:10.1038/s41398-018-0336-y.
  • Tahami Monfared, A. A., M. J. Byrnes, L. A. White, and Q. Zhang. 2022. The humanistic and economic burden of Alzheimer’s disease. Neurology and Therapy 11 (2):525–51. doi:10.1007/s40120-022-00335-x.
  • Tcw, J., L. Qian, N. H. Pipalia, M. J. Chao, S. A. Liang, Y. Shi, B. R. Jain, S. E. Bertelsen, M. Kapoor, E. Marcora, et al. 2022. Cholesterol and matrisome pathways dysregulated in astrocytes and microglia. Cell 185 (13):2213–33.e25. doi:10.1016/j.cell.2022.05.017.
  • Teixeira, A. L., C. S. Gama, N. P. Rocha, and M. M. Teixeira. 2018. Revisiting the role of eotaxin-1/CCL11 in psychiatric disorders. Frontiers in Psychiatry 9:241. doi:10.3389/fpsyt.2018.00241.
  • Tian, Z., X. Ji, and J. Liu. 2022. Neuroinflammation in vascular cognitive impairment and dementia: Current evidence, advances, and prospects. International Journal of Molecular Sciences 23 (11):6224. doi:10.3390/ijms23116224.
  • Wimo, A., M. Guerchet, G. C. Ali, Y. T. Wu, A. M. Prina, B. Winblad, L. Jönsson, Z. Liu, and M. Prince. 2017. The worldwide costs of dementia 2015 and comparisons with 2010. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association 13 (1):1–7. doi:10.1016/j.jalz.2016.07.150.
  • Xu, T., Y. Fang, A. Rong, and J. Wang. 2015. Flexible combination of multiple diagnostic biomarkers to improve diagnostic accuracy. BMC Medical Research Methodology 15 (1):94. doi:10.1186/s12874-015-0085-z.
  • Yang, S. Y., C. L. Shan, H. Qing, W. Wang, Y. Zhu, M. M. Yin, S. Machado, T. F. Yuan, and T. Wu. 2015. The effects of aerobic exercise on cognitive function of Alzheimer’s disease patients. CNS & Neurological Disorders Drug Targets 14 (10):1292–97. doi:10.2174/1871527315666151111123319.
  • Yilmaz, C., K. Karali, G. Fodelianaki, A. Gravanis, T. Chavakis, I. Charalampopoulos, and V. I. Alexaki. 2019. Neurosteroids as regulators of neuroinflammation. Frontiers in Neuroendocrinology 55:100788. doi:10.1016/j.yfrne.2019.100788.
  • Yu, J. T., W. Xu, C. C. Tan, S. Andrieu, J. Suckling, E. Evangelou, A. Pan, C. Zhang, J. Jia, L. Feng, et al. 2020. Evidence-based prevention of Alzheimer’s disease: Systematic review and meta-analysis of 243 observational prospective studies and 153 randomised controlled trials. Journal of Neurology, Neurosurgery, and Psychiatry 91 (11):1201–09. doi:10.1136/jnnp-2019-321913.
  • Zuliani, G., A. Ble’, R. Zanca, M. R. Munari, A. Zurlo, C. Vavalle, A. R. Atti, and R. Fellin. 2001. Lipoprotein profile in older patients with vascular dementia and Alzheimer’s disease. BMC Geriatrics 1 (1):5. doi:10.1186/1471-2318-1-5.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.