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Hemoglobin
international journal for hemoglobin research
Volume 31, 2007 - Issue 2
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Original

Molecular Basis of Thalassemia in Qatar

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Pages 121-127 | Received 25 Aug 2006, Accepted 27 Sep 2006, Published online: 07 Jul 2009

REFERENCES

  • Weatherall DJ, Clegg JB. The Thalassaemia Syndromes, 4th. Blackwell Science, Oxford 2001
  • Hardison RC, Chui DHK, Giardine B, Reimer C, Patrinos GP, Anagnou N, Miller W, Wajcman H. HbVar: a relational data base of human hemoglobin variants and thalassemia mutations at the globin gene server. Hum Mutat 2002; 19(3)225–233,
  • Patrinos GP, Giardine B, Reimer C, Miller W, Chui DHK, Anagnou NP, Wajcman H, Hardison RC. Improvements in the HbVar human hemoglobin variants and thalassemia mutations for population and sequence variation studies. Nucleic Acids Res 2004; 32(Database issue)D537–D541,
  • Al-Ali AK, Al-Ateeq S, Imamwerdi BW, Al-Sowayan S, Al-Madan M, Al-Muhanna F, Bashaweri L, Qaw F. Molecular bases of β-thalassemia in the eastern province of Saudi Arabia. J Biomed Biotechnol 2005; 2005(4)322–325
  • Adekile AD, Gu L-H, Baysal E, Haider MZ, Al-Fuzae L, Aboobacker KC, Al-Rashied A, Huisman THJ. Molecular characterization of α-thalassemia determinants, β-thalassemia alleles, and βShaplotypes among Kuwaiti Arabs. Acta Haematol 1994; 92(4)176–181
  • Jassim N, Merghoub T, Pascaud O, Al Mukharraq H, Ducrocq R, Labie D, Elion J, Krishnamoorthy R, Arrayed SA. Molecular basis of β-thalassemia in Bahrain: an epicenter for a Middle East specific mutation. Ann NY Acad Sci 1998; 850: 407–409
  • Daar S, Hussein HM, Merghoub T, Krishnamoorthy R. Spectrum of β-thalassemia mutations in Oman. Ann NY Acad Sci 1998; 850: 404–406
  • Fawzi ZO, Al Halali A, Fakhroo N, Al Bin Ali A, Al Mansour S. Distribution of hemoglobinopathies and thalassemias in Qatari Nationals seen at Hamad Hospital in Qatar. Qatar Med J 2003; 12(1)20–24
  • Cai SP, Wall J, Kan YW, Chehab FF. Reverse dot blot probes for screening of β-thalassemia mutations in Asians and Americans blacks. Hum Mutat 1994; 3(1)59–63
  • Maggio A, Giambona A, Cai SP, Wall J, Kan YW, Chehab FF. Rapid and simultaneous typing of Hemoglobin S, Hemoglobin C, and seven Mediterranean β-thalassemia mutations by covalent reverse dot-blot analysis: application to prenatal diagnosis in Sicily. Blood 1993; 81(1)239–242
  • Ghanem N, Girodon E, Vidaud M, Martin J, Fanen P, Plassa F, Goossens M. A comprehensive scanning method for rapid detection of β-globin gene mutations and polymorphisms. Hum Mutat 1992; 1(3)229–239
  • Jassim N, Al-Arrayed S, Gerard N, Al-Mukharraq H, Al-Ajami A, Ramasawmy R, Krishnamoorthy R. A mismatched-primer polymerase chain reaction-restriction fragment length polymorphism strategy for rapid screening of the polyadenylation signal mutation αT-Saudi(AATAAA→AATAAG) in the α2-globin gene. Hemoglobin 1999; 23(3)213–220
  • Baysal E, Huisman THJ. Detection of common deletional α-thalassemia-2 determinants by PCR. Am J Hematol 1994; 46(3)208–213
  • Orkin SH, Sexton JP, Goff SC, Kazazian HH. Inactivation of an acceptor RNA splice site by a short deletion in β-thalassemia. J Biol Chem 1983; 258(12)7249–7251
  • Orkin SH, Old JM, Weatherall DJ, Nathan DG. Partial deletion of β-globin gene DNA in certain patients with β0-thalassemia. Proc Natl Acad Sci USA 1979; 76(5)2400–2404
  • Quaife R, Al-Gazali L, Abbes S, Fitzgerald P, Fitches A, Valler D, Old JM. The spectrum of β thalassemia mutations in the UAE national population. J Med Genet 1994; 31(1)59–61
  • Najmabadi H, Karimi-Nejad R, Sahebjam S, Pourfarzad F, Teimourian S, Sahebjam F, Amirizadeh N, Karimi-Nejad MH. The β-thalassemia mutation spectrum in the Iranian population. Hemoglobin 2001; 25(3)285–296
  • Yavarian M, Harteveld CL, Batelaan D, Bernini LF, Giordano PC. Molecular spectrum of β-thalassemia in the Iranian province of Hormozgan. Hemoglobin 2001; 25(1)35–43
  • Zahed L. The spectrum of β-thalassemia mutations in the Arab populations. J Biomed Biotech 2001; 1(3)129–132
  • Dodé C, Krishnamoorthy R, Lamb J, Rochette J. Rapid analysis of −α3.7thalassaemia and αααanti3.7triplication by enzymatic amplification analysis. Br J Haematol 1992; 82(1)105–111
  • Driscoll MC, Dobkin CS, Alter BP. γδβ-Thalassemia due to a de novomutation deleting the 5′ β-globin gene activation-region hypersensitive sites. Proc Natl Acad Sci USA 1989; 86(19)7470–7474
  • Ho PJ, Hall GW, Watt S, West NC, Wimperis JW, Wood WG, Thein SL. Unusually severe heterozygous β-thalassemia: evidence for an interacting gene affecting globin translation. Blood 1998; 92(9)3428–3435
  • Giordano PC, Harteveld CL, Haak HL, Batelaan D, van Delft P, Plug RJ, Emonts M, Zanardini R, Bernini LF. A case of non-β-globin gene linked β thalassaemia in a Dutch family with two additional α-gene defects: the common −α3.7deletion and the rare IVS-I-116 (A→G) acceptor splice site mutation. Br J Haematol 1998; 103(2)370–376
  • Faa V, Meloni A, Moi L, Ibba G, Travi M, Vitucci A, Cao A, Rosatelli MC. Thalassaemia-like carriers not linked to the β-globin gene cluster. Br J Haematol 2006; 132(5)640–650
  • Kihm AJ, Kong Y, Wong W, Russell JE, Bouda S, Adachi K, Simon MC, Blobel GA, Weiss MJ. An abundant erythroid protein that stabilizes free α-haemoglobin. Nature 2002; 417(6890)758–763

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