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Hemoglobin
international journal for hemoglobin research
Volume 45, 2021 - Issue 3
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Brief Reports

A Novel β0-Thalassemia Mutation, HBB: c.356_357delTT [Codon 118 (–TT)] in an Iraqi Kurd

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Pages 212-214 | Received 21 Apr 2021, Accepted 25 May 2021, Published online: 24 Jun 2021

References

  • Weatherall DJ, Clegg JB. The Thalassaemia Syndromes. 4th ed. Oxford (Oxon, UK): Blackwell, 2001.
  • Globin Gene Server: HbVar database. http://globin.cse.psu.edu.
  • Danjou F, Francavilla M, Anni F, et al. A genetic score for the prediction of β-thalassemia severity. Haematologica. 2015;100(4):452–457.
  • Manca M. The Sardinian regional center for rare disease. Thalassemia Severity Score (TSS). A genetic based score for the predication of β thalassemia severity. Available at http://tss.unica.it/home/#.YIkiJ77_y71.
  • Al-Allawi NA, Al-Dousky AA. Frequency of haemoglobinopathies at premarital health screening in Dohuk, Iraq: implications for a regional prevention programme. East Mediterr Health J. 2010;16(4):381–385.
  • Polus R. Prevalence of hemoglobinopathies among marrying couples in Erbil province of Iraq. Iraqi J Hematol. 2017;6(2):90–93.
  • Al-Allawi N, Al Allawi S, Jalal SD. Genetic epidemiology of hemoglobinopathies among Iraqi Kurds. J Community Genet. 2021;12(1):5–14.
  • Préhu C, Pissard S, Al-Sheikh M, et al. Two French Caucasian families with dominant thalassemia-like phenotypes due to hyper unstable hemoglobin variants: Hb Sainte Seve [codon 118 (-T)] and codon 127 [CAG>TAG (Gln>stop]). Hemoglobin. 2005;29(3):229–233.
  • Kugler W, Enssle J, Hentze MW, et al. Nuclear degradation of nonsense mutated beta-globin mRNA: a post-transcriptional mechanism to protect heterozygotes from severe clinical manifestations of beta-thalassemia? Nucleic Acids Res. 1995;23(3):413–418.
  • Hopmeier P, Krugluger W, Gu L-H, et al. A newly discovered frameshift at codons 120-121 (+A) of the β gene is not associated with a dominant form of β-thalassemia. Blood. 1996;87(12):5393–5394.
  • Thein SL. The molecular basis of β-thalassemia. Cold Spring Harb Perspect Med. 2013;3(5):a011700.

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