295
Views
30
CrossRef citations to date
0
Altmetric
Research Article

Formulation and In Vitro Evaluation of Bisphosphonate Loaded Microspheres for Implantation in Osteolysis

, , &
Pages 473-481 | Published online: 25 Sep 2008

REFERENCES

  • Alex R., Bodmeier R. Encapsulation of water-soluble drugs by a modified solvent evaporation method. I. Effect of process and formulation variables on drug entrapment. J. Microencapsul 1990; 7(3)347–355, [INFOTRIEVE], [CSA]
  • Arica B., Calis S., Kas H. S., Hincal A. A. Chitosan microspheres of ibuprofen: evaluation and in vitro characterization. Chitosan in Pharmacy and Chemistry, R. A. A. Muzzarelli, C. Muzzarelli. Informa UK Ltd, Italy 2002a; 71–76
  • Arica B., Kas H. S., Orman M. N., Hincal A. A. Biodegradable bromocryptine mesylate microspheres prepared by a solvent evaporation technique: I. Evaluation of formulation variables on microspheres characteristics for brain delivery. J. Microencapsul 2002b; 19(4)473–484, [INFOTRIEVE], [CROSSREF], [CSA]
  • Bozdag S., Capan Y., Vural I., Dalkara T., Dogan A. L., Guc D., Hincal A. A., DeLuca P. P. Formulation and in vitro bioactivity of mitoxantrone-loaded biodegradable microspheres on rat glioma (RG2) cells. J. Drug Del. Sci. Tech 2005; 15(3)201–206, [CSA]
  • De Marco J. D., Biffar S. E., Reed D. G., Brooks M. A. The determination of 4-amino-1-hydroxybutane-1,1-diphosphonic acid monosodium salt trihydrate in pharmaceutical dosage forms by high-performance liquid chromatography. J. Pharm. Biomed. Anal 1989; 7(12)1719–1727, [INFOTRIEVE], [CROSSREF], [CSA]
  • Ezra A., Golomb G. Administration routes and delivery systems of bisphosphonates for the treatment of bone resorption. Adv. Drug Deliver. Rev 2000; 42: 175–195, [CROSSREF], [CSA]
  • Fan H., Dash A. K. Effect of cross-linking on the in vitro release kinetics of doxorubicin from gelatin implants. Int. J. Pharm 2001; 213: 103–116, [INFOTRIEVE], [CROSSREF], [CSA]
  • Ghaderi R., Sturesson C., Carlfors J. Effect of preparative parameters on the characteristics of poly(D,L-lactide-co-glycolide) microspheres made by double emulsion method. Int. J. Pharm 1996; 141: 205–216, [CROSSREF], [CSA]
  • Golomb G., Levi M., Van Gelder J. M. Controlled release of bisphosphonate from a biodegradable implant: Evaluation of release kinetics and anticalcification effect. Journal of Applied Biomaterials 1992; 3: 23–28, [CROSSREF], [CSA]
  • Hennink W. E., Nostrum C. F. Novel crosslinking methods to design hydrogels. Adv. Drug Deliver. Rev 2002; 54: 13–36, [CROSSREF], [CSA]
  • Herrmann J., Bodmeier R. The effect of particle microstructure on the somastatin release from poly(lactide) microspheres prepared by a W/O/W solvent evaporation method. J. Control. Release 1995; 36: 63–71, [CROSSREF], [CSA]
  • Jain R., Shah N. H., Malick A. W., Rhodes C. T. Controlled drug delivery by biodegradable poly (ester) devices: Different preparative approaches. Drug Dev. and Ind. Pharm 1998; 24(8)703–727, [CSA]
  • Jain R. A. The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices. Biomaterials 2000; 21: 2475–2490, [INFOTRIEVE], [CROSSREF], [CSA]
  • Kim K. J., Rubash H. E., Wilson S. C., D’Antonio J. A., McClain E. J. A histologic and biochemical comparison of the interface tissues in cementless and cemented hip prostheses. Clin. Orthop 1993; 287: 142–152, [INFOTRIEVE], [CSA]
  • Leo E., Pecquet S., Rojas J., Couvreur P., Fattal E. Changing the pH of the external aqueous phase may modulate protein entrapment and delivery from poly(lactide-co-glycolide) microspheres prepared by a w/o/w solvent evaporation method. J. Microencapsul 1998; 15(4)421–430, [INFOTRIEVE], [CSA]
  • Lin J. H., Chen I. W., DeLuna F. A. On the absorption of alendronate in rats. J. Pharm. Sci 1994; 83(12)1741–1746, [INFOTRIEVE], [CSA]
  • Mochida Y., Bauer T. W., Akisue T., Brown P. R. Alendronate does not inhibit early bone apposition to hydroxyapatite-coated total joint implants. J. Bone Joint Surg 2002; 84-A(2)226–235, [INFOTRIEVE], [CSA]
  • O’Donnell P. B., McGinity J. W. Preparation of microspheres by solvent evaporation technique. Adv. Drug Deliver. Rev 1997; 28: 25–42, [CROSSREF], [CSA]
  • Patashnik S., Rabinovich L., Golomb G. Preparation and evaluation of chitosan microspheres containing bisphosphonates. J. Drug Target 1997; 4(6)371–380, [INFOTRIEVE], [CSA]
  • Perugini P., Genta I., Conti B., Modena T., Pavanetto F. Long-term release of clodronate from biodegradable microspheres. AAPS Pharm. Sci. Tech 2001; 2(3)1–9, article 10[CSA]
  • Ravi Kumar M. N. V. A review of chitin and chitosan applications. Reactive & Functional Polymers 2000; 46: 1–27, [CROSSREF], [CSA]
  • Rosen C. J., Kessenich C. R. Comparative clinical pharmacology and therapeutic use of bisphosphonates in metabolic bone diseases. Drugs 1996; 51(4)537–551, [INFOTRIEVE], [CSA]
  • Sabokbar A., Fujikawa Y., Murray D. W., Athanasou N. A. Bisphosphonates in bone cement inhibit PMMA particle induced bone resorption. Ann. Rheum. Dis 1998; 57: 614–618, [INFOTRIEVE], [CSA]
  • Samdancioglu S., Calis S., Kir S., Sumnu M. The determination of alendronate sodium in microparticular systems by high performance liquid chromatography. FABAD J. Pharm. Sci 2003; 28(4)183–192, [CSA]
  • Sharpe M., Noble S., Spencer C. M. Alendronate: An update of its use in osteoporosis. Drugs 2001; 61(7)999–1039, [INFOTRIEVE], [CROSSREF], [CSA]
  • Thanoo B. C., Sunny M. C., Jayakrishnan A. Cross-linked chitosan microspheres: preparation and evaluation as a matrix for the controlled release of pharmaceuticals. J. Pharm. Pharmacol 1992; 44: 283–286, [INFOTRIEVE], [CSA]
  • Tuncay M., Calis S., Kas H. S., Ercan M. T., Peksoy I., Hincal A. A. Diclofenac sodium incorporated PLGA (50:50) microspheres: formulation considerations and in vitro/in vivo evaluation. Int. J. Pharm 2000; 195: 179–188, [INFOTRIEVE], [CROSSREF], [CSA]
  • Watts P. J., Davies M. C., Melia C. D. Microencapsulation using emulsification/solvent evaporation: an overview of techniques and applications. Crit. Rev. Drug Carrier Sys 1990; 7(3)235–258, [CSA]
  • Yenice I., Calis S., Atilla B., Kas H. S., Ozalp M., Ekizoglu M., Bilgili H., Hincal A. A. In vitro/in vivo evaluation of the efficiency of teicoplanin-loaded biodegradable microparticles formulated for implantation to infected bone defects. J. Microencapsul 2003; 20(6)705–717, [INFOTRIEVE], [CROSSREF], [CSA]

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.