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Research Article

Strategies to Overcome pH-Dependent Solubility of Weakly Basic Drugs by Using Different Types of Alginates

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Pages 1277-1284 | Published online: 20 Oct 2008

REFERENCES

  • K. Amighi, J. Timmermans, P. Puigdevall, E. Baltes, and A. J. Moes. (1998). Peroral sustained-release film coated pellets as a means to overcome physicochemical and biological drug related problems. I. In vitro development and evaluation. Drug Dev. Ind. Pharm. 24:509–515.
  • A. Dashevsky, K. Kolter, and R. Bodmeier. (2004). pH-independent release of a basic drug from pellets coated with the extended release polymer dispersion Kollicoat SR 30 D and the enteric polymer dispersion Kollicoat MAE 30 DP. Eur. J. Pharm. Biopharm. 58:45–49.
  • M. Efentakis, and G. Buckton. (2002). The effect of erosion and swelling on the dissolution of theophylline from low and high viscosity sodium alginate matrices. Pharm. Dev. Technol. 7:69–77.
  • FMC BioPolymer, and Technical information for Protanal. PhiladelphiaUSA, (2003) .
  • W. R. Gombotz, and S. F. Wee. (1998). Protein release from alginate matrices. Adv. Drug Deliv. Rev. 31:267–285.
  • C. Guthmann, R. Lipp, T. Wagner, and H. Kranz. (2007). Development of a multiple unit pellet formulation for a weakly basic drug. Drug Dev. Ind. Pharm. 33:341–349.
  • A. C. Hodsdon, J. R. Mitchell, M. C. Davies, and C. D. Melia. (1995). Structure and behaviour in hydrophilic matrix sustained release dosage forms: 3. The influence of pH on the sustained-release performance and internal gel structure of sodium alginate matrices. J. Control Release 33:143–152.
  • D. Hoerter, and J. D. Dressmann. (1997). Influence of physicochemical properties on dissolution of drugs in the gastrointestinal tract. Adv. Drug Deliv. Rev. 25:3–14.
  • H. Kranz, C. Guthmann, T. Wagner, R. Lipp, and J. Reinhard. (2005). Development of a single unit extended release formulation for ZK 811 752, a weakly basic drug. Eur. J. Pharm. Sci. 26:47–53.
  • C. V. Liew, L. W. Chan, A. L. Ching, and P. W. S Heng. (2006). Evaluation of sodium alginate as drug release modifier in matrix tablets. Int. J. Pharm. 309:25–37.
  • Merck & Co. Inc, and Merck index. Whitehouse Station, NJ, (2001) XII.
  • D. L. Munday. (2003). Film coated pellets containing verapamil hydrochloride: Enhanced dissolution into neutral medium. Drug Dev. Ind. Pharm. 29:575–583.
  • S. Nie, W. Pan, X. Li, and X. Wu. (2004). The effect of citric acid added to hydroxypropyl methylcellulose (HPMC) matrix tablets on the release profile of vinpocetine. Drug Dev. Ind. Pharm. 30:627–635.
  • A. Shilpa, S. S. Agrawal, and A. R. Ray. (2003). Controlled delivery of drugs from alginate matrix. J. Macromol. Sci. Polym. Rev., C 43:187–221.
  • S. Siepe, B. Lueckel, A. Kramer, A. Ries, and R. Gurny. (2006). Strategies for the design of hydrophilic matrix tablets with controlled microenvironmental pH. Int. J. Pharm. 316:14–20.
  • P. Sriamornsak, N. Thirawong, and K. Korkerd. (2007). Swelling, erosion and release behavior of alginate-based matrix tablers. Eur. J. Pharm. Biopharm. 66:435–450.
  • A. Streubel, J. Siepmann, A. Dashevsky, and R. Bodmeier. (2000). pH-independent release of a weakly basic drug from water-insoluble and -soluble matrix tablets. J. Control Release 67:101–110.
  • S. Takka, S. Rajbhandari, and A. Sakr. (2001). Effect of anionic polymers on the release of propranolol hydrochloride from matrix tablets. Eur. J. Pharm. Biopharm. 52:75–82.
  • P. Timmins, A. M. Delargy, and J. R. Howard. (1997). Optimization and characterization of a pH-independent extended release hydrophilic matrix tablet. Pharm. Dev. Technol. 2:25–31.

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