Transdermal Delivery of Tadalafil. I. Effect of Vehicles on Skin Permeation

References

• B. J. Aungst, J. A. Blake, M. A. Hussain. 1990. Contributions of drug solublization, partitioning, barrier disruption, and solvent permeation to the enhancement of skin permeation of various compounds with fatty acids and amines. Pharm. Res. 7:712–718.
   PubMed Web of Science ®Google Scholar
• A. K. Banga, S. Bose, T. K. Ghosh. 1999. Iontophoresis and electroporation: Comparisons and contrasts. Int. J. Pharm. 179:1–19.
   PubMed Web of Science ®Google Scholar
• B. W. Barry. 1983. Dermatological formulation: Percutaneous absorption. New York and Basel: Marcel Dekker.
   Google Scholar
• B. W. Barry. 1987. Mode of action of penetration enhancers in human skin. J. Control Rel. 6:85–97.
   Google Scholar
• D. Bommannan, R. O. Potts, R. H. Guy. 1991. Examination of the effect of ethanol on human stratum corneum in vivo using infrared spectroscopy. J. Control Rel. 16:299–304.
   Web of Science ®Google Scholar
• J. Buvat, H. Van Ahlen, H. Schmitt, H. Chan, C. Kuepfer, L. Varanese. 2006. Efficacy and safety of two dosing regimens of tadalafil and patterns of sexual activity in men with diabetes mellitus and erectile dysfunction: Scheduled use vs. on-demand regimen evaluation (SURE) study in 14 European countries. J. Sex. Med. 3 (3):512–520.
   PubMed Web of Science ®Google Scholar
• D. Chantasart, S. K. Li, N. He, K. S. Warner, S. Prakongpan, W. Higuchi. 2004. Mechanistic studies of branched-chain alkanols as skin permeation enhancers. J. Pharm. Sci. 93:762–779.
   PubMed Web of Science ®Google Scholar
• C. L. Cheng, C. H. Chou. 2005. Determination of tadalafil in small volumes of plasma by high performance liquid chromatography with UV detection. J. Chromatogr. B 822:278–284.
   PubMed Web of Science ®Google Scholar
• M. Corbo, J. C. Liu, Y. W. Chien. 1990. Bioavailability of propranolol following oral and transdermal administration in rabbits. J. Pharm. Sci. 79:584–587.
   PubMed Web of Science ®Google Scholar
• P. Costa, J. Buvat, S. Holmes, S. Weitckus, H. Petto, K. Hamidi, L. Varanese. 2006. Predictors of tadalafil efficacy in study comparing two dosing regimen. J. Sex. Med. 3 (6):1050–1058.
   PubMed Web of Science ®Google Scholar
• G. M. El Maghraby. 2008. Transdermal delivery of hydrocortisone from eucalyptus oil microemulsion: Effects of cosurfactants. Int. J. Pharm. 355:285–292.
   PubMed Web of Science ®Google Scholar
• G. M. El Maghraby, A. C. Williams, B. W. Barry. 1999. Skin delivery of oestradiol from deformable and traditional liposomes: Mechanistic studies. J. Pharm. Pharmacol. 51:1123–1134.
   PubMed Web of Science ®Google Scholar
• G. M. El Maghraby, A. C. Williams, B. W. Barry. 2000. Oestradiol skin delivery from ultradeformable liposomes: Refinement of surfactant concentration. Int. J. Pharm. 196:63–74.
   PubMed Web of Science ®Google Scholar
• G. M. El Maghraby, A. C. Williams, B. W. Barry. 2006. Can drug bearing liposomes penetrate intact skin?. J. Pharm Pharmacol. 58:415–429.
   PubMed Web of Science ®Google Scholar
• G. M. Golden, J. E. McKie, R. O. Potts. 1987. Role of stratum corneum lipid fluidity in transdermal drug flux. J. Pharm. Sci. 76:25–28.
   PubMed Web of Science ®Google Scholar
• S. R. Gorukanti, L. Li, K. H. Kim. 1999. Transdermal delivery of antiparkinsonian agent, benzotropine. I. Effect of vehicles on skin permeation. Int. J. Pharm. 192:159–172.
   PubMedGoogle Scholar
• G. M. El Maghraby, M. A. Hedaya, D. R. El-Afify. 2006. The effect of ciprofloxacin and clarithromycin on sildenafil oral bioavailability in human volunteers. Biopharm. Drug Dispos. 27:103–110.
   PubMed Web of Science ®Google Scholar
• T. Higuchi. 1960. Physical chemical analysis of percutaneous absorption process from creams and ointments. J. Soc. Cosmet. Chem. 11:85–97.
   Web of Science ®Google Scholar
• T. Holas, K. Vávrová, M. Sima, J. Klimentová, A. Hrabálek. 2006. Synthesis and transdermal permeation-enhancing activity of carbonate and carbamate analogs of transkarbam 12. Bioorg. Med. Chem. 14:7671–7680.
   PubMed Web of Science ®Google Scholar
• A. Hrabálek, K. Vávrová, P. Dolezal, M. Machácek. 2005. Esters of 6-aminohexanoic acid as skin permeation enhancers: The effect of branching in the alkanol moiety. J. Pharm. Sci. 94:1494–1499.
   PubMed Web of Science ®Google Scholar
• A. Jetter, M. Kinzig-Schippers, M. Walchner-Bonjean, U. Hering, J. Bulitta, P. Schreiner, F. Sorgel, U. Fuhr. 2002. Effects of grapefruit juice on the pharmacokinetics of sildenafil. Clin. Pharmacol. Ther. 71:21–29.
   PubMed Web of Science ®Google Scholar
• L. Kikwai, N. Kanikkannan, R. J. Babu, M. Singh. 2002. Effect of vehicles on the transdermal delivery of melatonin across porcine skin in vitro. J. Control Rel. 83:307–311.
   PubMed Web of Science ®Google Scholar
• K. Knutson, S. L. Krill, J. Zhang. 1990. Solvent mediated alteration of the stratum corneum. J. Control Rel. 11:93–103.
   Web of Science ®Google Scholar
• J. Kost, U. Pliquett, S. Mitragotri, A. Yamamoto, R. Langer, J. Weaver. 1996. Synergistic effect of electric field and ultrasound on transdermal transport. Pharm. Res. 13:633–638.
   PubMed Web of Science ®Google Scholar
• Y. S. R. Krishnaiah, V. Satyanarayana, R. S. Karthikeyan. 2002. Effect of the solvent system on the in vitro permeability of nicardipine hydrochloride through excised rat epidermis. J. Pharm. Pharm. Sci. 5:124–130.
   Google Scholar
• M. L. Leichtnam, H. Roland, P. Wuthrich, R. H. Guy. 2006. Enhancement of transdermal testosterone delivery by supersaturation. J. Pharm. Sci. 95:2373–2379.
   PubMed Web of Science ®Google Scholar
• M. Mezei, V. Gulasekharam. 1980. Liposomes—a selective drug delivery system for topical route of administration. 1. Lotion dosage form. Life Sci. 26:1473–1477.
   PubMed Web of Science ®Google Scholar
• L. L. Miller, C. J. Kolaskie, G. A. Smith, J. Rivier. 1990. Transdermal iontophoresis of gonadotropin releasing hormone and two analogues. J. Pharm. Sci. 79:490–493.
   PubMed Web of Science ®Google Scholar
• B. Mollgaard, A. Hoelgaard. 1983. Vehicle effect on topical drug delivery. I. Influence of glycol and drug concentration on skin transport. Acta Pharm. Suec. 20:433–442.
   PubMedGoogle Scholar
• G. J. Muirhead, S. Faulken, J. A. Harness, J. Taubel. 2002. The effect of steady state erythromycin and azithromycin onpharmacokinetics of sildenafil in healthy volunteers. Br. J. Clin. Pharmacol. 53:37S–43S.
   PubMed Web of Science ®Google Scholar
• G. J. Muirhead, M. B. Wulff, A. Fielding, D. Kleinermans, N. Buss. 2000. Pharmacokinetic interactions between sildenafil and saquinavir/ritonavir. Br. J. Clin. Pharmacol. 50:99–107.
   PubMed Web of Science ®Google Scholar
• R. Panchagnula, H. Desu, A. Jain, S. Khandavilli. 2005. Feasibility studies of dermal delivery of paclitaxil with binary combinations of ethanol and isopropyl myristate: Role of solubility, partitioning and lipid bilayer perturbation. Il Farmaco 60:894–899.
   PubMedGoogle Scholar
• R. Panchagnula, P. S. Salve, N. S. Thomas, A. K. Jain, P. Ramarao. 2001. Transdermal delivery of naloxone: Effect of water, propylene glycol, ethanol and their combinations on the permeation through rat skin. Int. J. Pharm. 219:95–105.
   PubMed Web of Science ®Google Scholar
• H. Porst, H. Padma-Nathan, F. Giuliano, G. Anglin, L. Varanese, R. Rosen. 2003. Efficacy of tadalafil for the treatment of erectile dysfunction at 24 and 36 hours after dosing: A randomized controlled trial. Urology 62 (1):121–125.
   PubMed Web of Science ®Google Scholar
• Y. S. Rhee, J. Y. Huh, C. W. Park, T. Y. Nam, K. R. Yoon, S. C. Chi, E. S. Park. 2007. Effects of vehicles and enhancers on transdermal delivery of clebopride. Arch. Pharm. Res. 30:1155–1161.
   PubMed Web of Science ®Google Scholar
• B. J. Ring, B. E. Patterson, M. I. Mitchel, J. Gillespie, A. W. Bedding, H. Jewell, C. D. Payne, S. T. Forgue, J. Eckstein, S. A. Wrighton, D. L. Phillips. 2005. Effect of tadalafil on cytochrome P450 3A4-mediated clearance: Studies in vitro and in vivo. Clin. Pharmacol. Ther. 77 (1):63–75.
   PubMed Web of Science ®Google Scholar
• H. Schreier, J. Bouwstra. 1994. Liposomes and niosomes as topical drug carriers: Dermal and transdermal drug delivery. J. Control Rel. 30:1–15.
   Web of Science ®Google Scholar
• R. Shabsigh, A. D. Seftel, R. C. Rosen, H. Porst, S. Ahuja, M. C. Deeley, C. S. Garcia, F. Giuliano. 2006. Review of time of onset and duration of clinical efficacy of phosphodiesterase type 5 inhibitors in treatment of erectile dysfunction. Urology 68:689–696.
   PubMed Web of Science ®Google Scholar
• D. O. Sussman. 2004. Pharmacokinetics, pharmacodynamics and efficacy of phosphodiesterase type 5 inhibitors. J. Am. Osteopath. Assoc. 104 (3):S11–S15.
   Google Scholar
• K. Takahashi, S. Tamagawa, T. Katagi, H. Yoshitomi, A. Kamada, J. H. Rytting, T. Nishihata, N. Mizuno. 1991. In vitro transport of sodium diclofenac across rat abdominal skin: Effect of selection of oleaginous component and the addition of alcohols to the vehicle. Chem. Pharm. Bull. 39:154–158.
   PubMed Web of Science ®Google Scholar
• N. S. Thomas, R. Panchagnula. 2003. Transdermal delivery of zidovudine: Effect of vehicles on permeation across rat skin and their mechanism of action. Eur. J. Pharm. Sci. 18:71–79.
   PubMed Web of Science ®Google Scholar
• E. Touitou, N. Dayan, L. Bergelson, B. Godin, M. Eliaz. 2000. Ethosomes—novel vesicular carriers for enhanced delivery: Characterization and skin penetration properties. J. Control Rel. 65:403–418.
   PubMed Web of Science ®Google Scholar
• J. N. Twist, J. L. Zatz. 1988. Membrane–solvent–solute interaction in a model permeation system. J. Pharm. Sci. 77:536–540.
   PubMed Web of Science ®Google Scholar
• K. Vávrová, J. Zbytovská, A. Hrabálek. 2005. Amphiphilic transdermal permeation enhancers: Structure–activity relationship. Curr. Med. Chem. 12 (19):2273–2291.
   PubMed Web of Science ®Google Scholar
• A. C. Williams, B. W. Barry. 2004. Penetration enhancers. Adv. Drug Del. Rev. 56:603–618.
   PubMed Web of Science ®Google Scholar
• K. Wilner, L. Laboy, M. LeBel. 2002. The effects of cimetidine and antacid on the pharmacokinetic profile of sildenafil citrate in healthy male volunteers. Br. J. Clin. Pharmacol. 53:31S–36S.
   PubMed Web of Science ®Google Scholar