Advanced search
Publication Cover
Drug Development and Industrial Pharmacy Volume 35, 2009 - Issue 9
Submit an article Journal homepage
596
Views
23
CrossRef citations to date
0
Altmetric
Original Article

Functional performance of silicified microcrystalline cellulose versus microcrystalline cellulose: a case study

Ahmad Aljaberi Pharmaceutical & Analytical Research & Development Department, Hoffmann La-Roche, Nutley, NJ, USA
,
Ashish Chatterji Pharmaceutical & Analytical Research & Development Department, Hoffmann La-Roche, Nutley, NJ, USA
,
Navnit H. Shah Pharmaceutical & Analytical Research & Development Department, Hoffmann La-Roche, Nutley, NJ, USA
&
Harpreet K. Sandhu Pharmaceutical & Analytical Research & Development Department, Hoffmann La-Roche, Nutley, NJ, USACorrespondence[email protected]
Pages 1066-1071 | Received 11 Jun 2008, Accepted 24 Jan 2009, Published online: 19 May 2009

References

  • Bolhuis GK, Armstrong NA. (2006). Excipients for direct compaction—an update. Pharm Dev Technol, 11:111–24.
  • Gohel MC, Jogani PD. (2005). A review of co-processed directly compressible excipients. J Pharm Pharm Sci, 16:76–93.
  • Hwang RC, Peck GR. (2001). A systematic evaluation of the compression and tablet characteristics of various types of microcrystalline cellulose. Pharm Technol, 25:112–32.
  • Van Veen B, Bolhuis GK, Wu YS, Zuurman K, Frijlink HW. (2005). Compaction mechanism and tablet strength of unlubricated and lubricated (silicified) microcrystalline cellulose. Eur J Pharm Biopharm, 59:133–8.
  • Lerk CF, Bolhuis GK, Smedema SS. (1977). Interaction of lubricants and colloidal silica during mixing with excipients. I. Its effect on tabletting. Pharm Acta Helv, 52:33–9.
  • Habib YS, Abramowitz R, Jerzewski RL, Jain NB, Agharkar SN. (1999). Is silicified wet-granulated microcrystalline cellulose better than original wet-granulated microcrystalline cellulose?. Pharm Dev Technol, 4:431–7.
  • Edge S, Potter UJ, Steele DF, Tobyn MJ, Chen A, Staniforth JN. (1999). The location of silicon dioxide in silicified microcrystalline cellulose. Pharm Pharmacol Commun, 5:371–6.
  • Tobyn MJ, McCarthy GP, Staniforth JN, Edge S. (1998). Physicochemical comparison between microcrystalline cellulose and silicified microcrystalline cellulose. Int J Pharm, 169:183–94.
  • Buckton G, Yonemochi E, Yoon WL, Moffat AC. (1991). Water sorption and near IR spectroscopy to study the differences between microcrystalline cellulose and silicified microcrystalline cellulose before and after wet granulation. Int J Pharm, 181:41–7.
  • Muzikova J, Novakova P. (2007). A study of the properties of compacts from silicified microcrystalline celluloses. Drug Dev Ind Pharm, 33:775–81.
  • Sandhu HK, Chatterji A, Shah NH, Malick AW, Desai D, Zia H. (2007). Effect of formulation and processing variables on the granulation kinetics of hot melt granulation (HMG) process. Pharm Dev Technol, 12:145–51.
  • Chatterji A, Sandhu HK, Shah NH. (2007) .Pharmaceutical composition and process. US patent application 2007/0184113 A1.
  • Kachrimanis K, Noisternig MF, Griesser UJ, Malamataris S. (2006). Dynamic moisture sorption and desorption of standard and silicified microcrystalline cellulose. Eur J Pharm Biopharm, 64:307–15.
  • JRS Pharma LP, Prosolv SMCC®: Silicified microcrystalline cellulose, Technical literature.
  • Steele DF, Edge S, Tobyn MJ, Moreton RC, Staniforth JN. (2003). Adsorption of an amine drug onto microcrystalline cellulose and silicified microcrystalline cellulose samples. Drug Dev Ind Pharm, 29:475–87.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.