Evaluation of the methylene blue addition in binary polymeric systems composed by poloxamer 407 and Carbopol 934P using quality by design: rheological, textural, and mucoadhesive analysis

References

• Perussi JR. Inativação fotodinâmica de microrganismos. Quim Nova 2007;30:988–94.
   Web of Science ®Google Scholar
• Teichert MC, Jones JW, Usacheva MN, Biel MA. Treatment of oral candidiasis with methylene blue-mediated photodynamic therapy in an immunodeficient murine model. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002;93:155–60.
   PubMed Web of Science ®Google Scholar
• Schmidt TF, Caseli L, Oliveira ON, Itri R. Binding of methylene blue onto langmuir monolayers representing cell membranes may explain its efficiency as photosensitizer in photodynamic therapy. Langmuir 2015;31:4205–12.
   PubMed Web of Science ®Google Scholar
• Miyabe M, Junqueira JC, da Costa ACBP, et al. Effect of photodynamic therapy on clinical isolates of staphylococcus spp. Braz Oral Res 2011;25:230–4.
   PubMed Web of Science ®Google Scholar
• Souza LWF, Souza SV, Botelho AC. Randomized controlled trial comparing photodynamic therapy based on methylene blue dye and fluconazole for toenail onychomycosis. Dermatol Ther 2014;27:43–7.
   PubMed Web of Science ®Google Scholar
• Tardivo JP, Del GA, de Oliveira CS, et al. Methylene blue in photodynamic therapy: from basic mechanisms to clinical applications. Photodiagnosis Photodyn Ther 2005;2:175–91.
   PubMed Web of Science ®Google Scholar
• Zeina B, Greenman J, Purcell WM, Das B. Killing of cutaneous microbial species by photodynamic therapy. Br J Dermatol 2001;144:274–8.
   PubMed Web of Science ®Google Scholar
• Gabrielli D, Belisle E, Severino D, et al. Binding, aggregation and photochemical properties of methylene blue in mitochondrial suspensions. Photochem Photobiol 2004;79:227–32.
   PubMed Web of Science ®Google Scholar
• Benito M, Martín V, Blanco MD, et al. Cooperative effect of 5-aminolevulinic acid and gold nanoparticles for photodynamic therapy of cancer. J Pharm Sci 2013;102:2760–9.
   PubMed Web of Science ®Google Scholar
• Chen Y, Zheng W, Li Y, et al. Apoptosis induced by methylene-blue-mediated photodynamic therapy in melanomas and the involvement of mitochondrial dysfunction revealed by proteomics. Cancer Sci 2008;99:2019–27.
   PubMed Web of Science ®Google Scholar
• Peloi LS, Biondo CEG, Kimura E, et al. Photodynamic therapy for American cutaneous leishmaniasis: the efficacy of methylene blue in hamsters experimentally infected with Leishmania (Leishmania) amazonensis. Exp Parasitol 2011;128:353–6.
   PubMed Web of Science ®Google Scholar
• Bonacucina G, Martelli S, Palmieri GF. Rheological, mucoadhesive and release properties of Carbopol gels in hydrophilic cosolvents. Int J Pharm 2004;282:115–30.
   PubMed Web of Science ®Google Scholar
• Carvalho FC, Bruschi ML, Evangelista RC, Gremião MPD. Mucoadhesive drug delivery systems. Braz J Pharm Sci 2010;46:1–17.
   Web of Science ®Google Scholar
• Jones DS, Bruschi ML, de Freitas O, et al. Rheological, mechanical and mucoadhesive properties of thermoresponsive, bioadhesive binary mixtures composed of poloxamer 407 and carbopol 974P designed as platforms for implantable drug delivery systems for use in the oral cavity. Int J Pharm 2009;372:49–58.
   PubMed Web of Science ®Google Scholar
• Villanova JCO, Oréfice RL, Cunha AS. Aplicações Farmacêuticas de Polímeros. Polímeros Ciência E Tecnol 2010;20:51–64.
   Web of Science ®Google Scholar
• Caramella CM, Rossi S, Ferrari F, et al. Mucoadhesive and thermogelling systems for vaginal drug delivery. Adv Drug Deliv Rev 2015;92:39–52.
   PubMed Web of Science ®Google Scholar
• Almeida H, Amaral MH, Lobão P, Lobo JMS. In situ gelling systems: a strategy to improve the bioavailability of ophthalmic pharmaceutical formulations. Drug Discov Today 2014;19:400–12.
   PubMed Web of Science ®Google Scholar
• Dumortier G, Grossiord JL, Agnely F, Chaumeil JC. A review of poloxamer 407 pharmaceutical and pharmacological characteristics. Pharm Res 2006;23:2709–28.
   PubMed Web of Science ®Google Scholar
• Kabanov AV, Batrakova EV, Alakhov VY. Pluronic block copolymers as novel polymer therapeutics for drug and gene delivery. J Control Release 2002;82:189–212.
   PubMed Web of Science ®Google Scholar
• Bruschi ML, Jones DS, Panzeri H, et al. Semisolid systems containing propolis for the treatment of periodontal disease: in vitro release kinetics, syringeability, rheological, textural, and mucoadhesive properties. J Pharm Sci 2007;96:2074–89.
   PubMed Web of Science ®Google Scholar
• Fabri FV, Cupertino RR, Hidalgo MM, et al. Preparation and characterization of bioadhesive systems containing propolis or sildenafil for dental pulp protection. Drug Dev Ind Pharm 2011;37:1446–54.
   PubMed Web of Science ®Google Scholar
• Ferreira SB, de S, Dias BR, et al. Microparticles containing propolis and metronidazole: in vitro characterization, release study and antimicrobial activity against periodontal pathogens. Pharm Dev Technol 2013;19:173–80.
   PubMed Web of Science ®Google Scholar
• Borghi-Pangoni FB, Junqueira MV, de Souza Ferreira SB, et al. Screening and in vitro evaluation of mucoadhesive thermoresponsive system containing methylene blue for local photodynamic therapy of colorectal cancer. Pharm Res 2015;33:776–91.
   PubMed Web of Science ®Google Scholar
• Junqueira MV, Borghi-Pangoni FB, Ferreira SBS, et al. Functional polymeric systems as delivery vehicles for methylene blue in photodynamic therapy. Langmuir 2016;32:19–27.
   PubMed Web of Science ®Google Scholar
• Pereira RRDA, Ribeiro Godoy JS, Stivalet Svidzinski TI, Bruschi ML. Preparation and characterization of mucoadhesive thermoresponsive systems containing propolis for the treatment of vulvovaginal candidiasis. J Pharm Sci 2013;102:1222–34.
   PubMed Web of Science ®Google Scholar
• Jones DS. Pharmaceutical statistics. London, UK: Pharmaceutical Press; 2002:586.
   Google Scholar
• Pereira RRA, Ribeiro Godoy JS, Estivalet Svidzinski TI, Bruschi ML. Preparation and characterization of mucoadhesive thermoresponsive systems containing propolis for the treatment of vulvovaginal candidiasis. J Pharm Sci 2013;102:4215–27.
   Google Scholar
• Andrews GP, Gorman SP, Jones DS. Rheological characterisation of primary and binary interactive bioadhesive gels composed of cellulose derivatives designed as ophthalmic viscosurgical devices. Biomaterials 2005;26:571–80.
   PubMed Web of Science ®Google Scholar
• Chen J, Zhou R, Li L, et al. Mechanical, rheological and release behaviors of a poloxamer 407/ poloxamer 188/carbopol 940 thermosensitive composite hydrogel. Molecules 2013;18:12415–25.
   PubMed Web of Science ®Google Scholar
• Wei G, Xu H, Ding PT, et al. Thermosetting gels with modulated gelation temperature for ophthalmic use: the rheological and gamma scintigraphic studies. J Control Release 2002;83:65–74.
   PubMed Web of Science ®Google Scholar
• Chang JY, Oh Y-K, Kong HS, et al. Prolonged antifungal effects of clotrimazole-containing mucoadhesive thermosensitive gels on vaginitis. J Control Release 2002;82:39–50.
   PubMed Web of Science ®Google Scholar
• Jeong B, Kim SW, Bae YH. Thermosensitive sol-gel reversible hydrogels. Adv Drug Deliv Rev 2012;64:154–62.
   Web of Science ®Google Scholar
• Choi HG, Jung JH, Ryu JM, et al. Development of in situ gelling and mucoadhesive acetaminophen liquid suppository. Int J Pharm 1998;16:533–44.
   Google Scholar
• Baloglu E, Karavana SY, Senyigit ZA, Guneri T. Rheological and mechanical properties of poloxamer mixtures as a mucoadhesive gel base. Pharm Dev Technol 2011;16:627–36.
   PubMed Web of Science ®Google Scholar
• Ribeiro JN, Jorge RA, Da Silva AR, et al. Avaliação da atividade fotodinâmica de porfirinas para uso em terapia fotodinâmica através da fotoxidação de triptofano. Eclet Quim 2007;32:7–14.
   Google Scholar
• Andrews GP, Laverty TP, Jones DS. Mucoadhesive polymeric platforms for controlled drug delivery. Eur J Pharm Biopharm 2009;71:505–18.
   PubMed Web of Science ®Google Scholar
• Figueiras A, Carvalho R, Veiga F. Mucoadhesive drug delivery systems in the oral cavity: Mucoadhesive mechanism and mucoadhesive polymers. Revista Lusófona De Ciências E Tecnologias Da Saúde 2007;1:216–33.
   Google Scholar