257
Views
5
CrossRef citations to date
0
Altmetric
Research Articles

Influences of copolymers (Copovidone, Eudragit RL PO and Kollicoat MAE 30 DP) on stability and bioactivity of spray-dried and freeze-dried lysozyme

, , &
Pages 2086-2096 | Received 18 Jan 2016, Accepted 05 Jun 2016, Published online: 26 Jun 2016

References

  • Espiritu MJ, Collier AC, Bingham J. A 21st-century approach to age-old problems: the ascension of biologics in clinical therapeutics. Drug Discov Today 2014;19:1109–13.
  • Haj-Ahmad RR, Elkordy AA, Chaw CS, Moore A. Compare and contrast the effects of surfactants (Pluronic®F-127 and Cremophor®EL) and sugars (β-cyclodextrin and inulin) on properties of spray dried and crystallised lysozyme. Eur J Pharm Sci 2013;49:519–34.
  • Roughton BC, Pokphanh AI, Topp EM, Camarda KV. Optimizing protein-excipient interactions for the development of aggregation-reducing lyophilized formulations. 11th International Symposium on Process Systems Engineering, Pts A and B 2012;31:1351–5.
  • Harsha SN, Aldhubiab BE, Nair AB, et al. Nanoparticle formulation by Buchi B-90 Nano Spray Dryer for oral mucoadhesion. Drug Des Dev Ther 2015;9:273–82.
  • Forbes RT, Barry BW, Elkordy AA. Preparation and characterisation of spray-dried and crystallised trypsin: FT-Raman study to detect protein denaturation after thermal stress. Eur J Pharm Sci 2007;30:315–23.
  • Serafin AM, Akudugu JM, Bohm L. Influence of freeze-drying on the recovery of the tumour invasion markers uPA and PAI-1 from prostate cancer resections. Ann Clin Biochem 2015;52:387–94.
  • Santana H, Sotolongo J, Gonzalez Y, et al. Stabilization of a recombinant human epidermal growth factor parenteral formulation through freeze-drying. Biologicals 2014;42:322–33.
  • Fonte P, Soares S, Sousa F, et al. Stability study perspective of the effect of freeze-drying using cryoprotectants on the structure of insulin loaded into PLGA nanoparticles. Biomacromolecules 2014;15:3753–65.
  • Costa-Silva TA, Souza CRF, Oliveira WP, Said S. Characterization and spray drying of lipase produced by the endophytic fungus Cercospora kikuchii. Brazilian J Chem Eng 2014;31:849–58.
  • Hulse WL, Forbes RT, Bonner MC, Getrost M. Do co-spray dried excipients offer better lysozyme stabilisation than single excipients? Eur J Pharm Sci 2008;33:294–305.
  • Maury M, Murphy K, Kumar S, et al. Spray-drying of proteins: effects of sorbitol and trehalose on aggregation and FT-IR amide I spectrum of an immunoglobulin G. Eur J Pharm Biopharm 2005;59:251–61.
  • Jacob S, Shirwaikar AA, Srinivasan KK, et al. Stability of proteins in aqueous solution and solid state. Indian J Pharm Sci 2006;68:154–63.
  • Akers MJ, Defelippis MR. Peptides and proteins as parenteral solutions. In: Hovgaard L, Frokjaer S, van de Weert M, eds. Pharmaceutical formulation development of peptides and proteins. 2nd edn. Philadelphia, PA: Taylor and Francis; 2012:149–92.
  • Hamada H, Arakawa T, Shiraki K. Effect of additives on protein aggregation. Curr Pharm Biotechnol 2009;10:400–7.
  • Bischof J, He X. Thermal stability of proteins. Ann NY Acad Sci 2005;1066:12–33.
  • Nagendra H, Sukumar N, Vijayan M. Role of water in plasticity, stability, and action of proteins: the crystal structures of lysozyme at very low levels of hydration. Proteins: Struct Funct Genet 1998;32:229–40.
  • Al-Hussein A, Gieseler H. Investigation of the stabilizing effects of hydroxyethyl cellulose on LDH during freeze drying and freeze thawing cycles. Pharm Dev Technol 2015;20:50–9.
  • Fang W, Qi W, Kinzell J, et al. Effects of excipients on the chemical and physical stability of glucagon during freeze-drying and storage in dried formulations. Pharm Res 2012;29:3278–91.
  • Zhang Y, Deng Y, Wang X, et al. Conformational and bioactivity analysis of insulin: freeze-drying TBA/water co-solvent system in the presence of surfactant and sugar. Int J Pharm 2009;371:71–81.
  • Lee T, Lin S. Pluronic F68 enhanced the conformational stability of salmon calcitonin in both aqueous solution and lyophilized solid form. Biopolymers 2011;95:785–91.
  • Kadoya S, Fujii K, Izutsu K, et al. Freeze-drying of proteins with glass-forming oligosaccharide-derived sugar alcohols. Int J Pharm 2010;389:107–13.
  • England JL. Stabilization and release effects of pluronic polyols in protein drug delivery. J Undergrad Sci 1998;5:17–24.
  • Haj-Ahmad RR, Chen YT, Elkordy AA. An overview for the effects of lactitol, gelucire 44/14 and copovidone on lysozyme biological activity. Eur J Biomed Pharm Sci 2015;2:1328–39.
  • Gandhi A, Jana S, Sen KK. In-vitro release of acyclovir loaded Eudragit RLPO(®) nanoparticles for sustained drug delivery. Int J Biol Macromol 2014;67:478–82.
  • Elkordy AA, Forbes RT, Barry BW. Integrity of crystalline lysozyme exceeds that of a spray-dried form. Int J Pharm 2002;247:79–90.
  • Elkordy AA, Forbes RT, Barry BW. Stability of crystallised and spray-dried lysozyme. Int J Pharm 2004;278:209–19.
  • Cegielska-Radziejewska R, Lesnierowski G, Kijowski J. Properties and application of egg white lysozyme and its modified preparations. Polish J Nutr Sci 2008;58:5–10.
  • Humphrey BD, Huang N, Klasing KC. Rice expressing lactoferrin and lysozyme has antibiotic-like properties when fed to chicks. J Nutr 2002;132:1214–18.
  • Lee-Huang S, Huang PL, Sun Y, et al. Lysozyme and RNases as anti-HIV components in beta-core preparations of human chorionic gonadotropin. Proc Natl Acad Sci USA 1999;96:2678–81.
  • Wang W. Lyophilization and development of solid protein pharmaceuticals. Int J Pharm 2000;203:1–60.
  • Shugar D. The measurement of lysozyme activity and the ultra-violet inactivation of lysozyme. Biochim Biophys Acta 1952;8:302–9.
  • Yadav SK, Mishra S, Mishra B. Eudragit-based nanosuspension of poorly water-soluble drug: formulation and in vitro-in vivo evaluation. AAPS PharmSciTech 2012;13:1031–44.
  • Hulse WL, Forbes RT, Bonner MC, Getrost M. Influence of protein on mannitol polymorphic form produced during co-spray drying. Int J Pharm 2009;382:67–72.
  • Prinn KB, Costantino HR, Tracy M. Statistical modeling of protein spray drying at the lab scale. AAPS PharmSciTech 2002;3:E4.
  • Wang FJ, Wang CH. Effects of fabrication conditions on the characteristics of etanidazole spray-dried microspheres. J Microencapsul 2002;19:495–510.
  • Fatouros A, Osterberg T, Mikaelsson M. Recombinant factor VIII SQ - inactivation kinetics in aqueous solution and the influence of disaccharides and sugar alcohols. Pharm Res 1997;14:1679–84.
  • Claus S, Weiler C, Schiewe J, Friess W. Optimization of the fine particle fraction of a lyophilized lysozyme formulation for dry powder inhalation. Pharm Res 2013;30:1698–713.
  • Wang X, Yin D, Zhang C, et al. Effect of temperature programmes on protein crystallisation. Crystal Res Technol 2010;45:479–89.
  • Li Y, He W, Dong Y, et al. Human serum albumin interaction with formononetin studied using fluorescence anisotropy, FT-IR spectroscopy, and molecular modeling methods. Bioorg Med Chem 2006;14:1431–6.
  • Lei Z, Geng X, Dai L, Geng X. [DSC and FTIR study of adsorbed lysozyme on hydrophobic surface]. Guang Pu Xue Yu Guang Pu Fen Xi 2008;28:2058–61.
  • Vidal BDC, Mello MLS. Collagen type I amide I band infrared spectroscopy. Micron 2011;42:283–9.
  • Dourado F, Bastos M, Mota M, Gama F. Studies on the properties of Celluclast/Eudragit L-100 conjugate. J Biotechnol 2002;99:121–31.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.