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Research Articles

Development and characterization of a mucoadhesive sublingual formulation for pain control: extemporaneous oxycodone films in personalized therapy

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Pages 917-924 | Received 03 Nov 2016, Accepted 09 Jan 2017, Published online: 31 Jan 2017

References

  • Davies AN, Dickman A, Reid C, et al. The management of cancer-related breakthrough pain: Recommendations of a task group of the Science Committee of the Association for Palliative Medicine of Great Britain and Ireland. Eur J Pain 2009;13:331–8.
  • Zeppetella G, Davies A, Eijgelshoven I, et al. A network meta-analysis of the efficacy of opioid analgesics for the management of breakthrough cancer pain episodes. J Pain Symptom Manage 2014;47:772–85.
  • Khan S, Trivedi V, Mitchell J, et al. Conversion of sustained release omeprazole loaded buccal films into fast dissolving strips using supercritical carbon dioxide (scCO2) processing, for potential paediatric drug delivery. Eur J Pharm Sci 2016;93:45–55.
  • Khan S, Trivedi V, Boateng J. Functional physico-chemical, ex vivo permeation and cell viability characterization of omeprazole loaded buccal films for paediatric drug delivery. Int J Pharm 2016;500:217–26.
  • Preis M, Woertz C, Kleinebudde P, et al. Oromucosal film preparations: classification and characterization methods. Expert Opin Drug Deliv 2013;10:1303–17.
  • Hoffmann EM, Breitenbach A, Breitkreutz J. Advances in orodispersible films for drug delivery. Expert Opin Drug Deliv 2011;8:299–316.
  • Slavkova M, Breitkreutz J. Orodispersible drug formulations for children and elderly. Eur J Pharm Sci 2015;75:2–9.
  • Preis M. Orally disintegrating films and mini-tablets—innovative dosage forms of choice for pediatric use. AAPS PharmSciTech 2015;16:234–41.
  • Coluzzi PH, Schwartzberg L, Conroy JD, et al. Breakthrough cancer pain: a randomized trial comparing oral transmucosal fentanyl citrate (OTFC®) and morphine sulfate immediate release (MSIR®). Pain 2001;91:123–30.
  • Kellaway IW, Ponchel G, Duchêne D. Oral mucosal drug delivery. In: Rathbone MJ, Hadgraft J, ed. Modified release drug delivery technology. New York (NY): Marcel Dekker Inc.; 2003:349–350.
  • Şenel S, Rathbone MJ, Cansız M, et al. Recent developments in buccal and sublingual delivery systems. Expert Opin Drug Deliv 2012;9:615–28.
  • Asane GS, Nirmal SA, Rasal KB, et al. Polymers for mucoadhesive drug delivery system: a current status. Drug Dev Ind Pharm 2008;34:1246–66.
  • Agarwal S, Aggarwal S. Mucoadhesive polymeric platform for drug delivery; a comprehensive review. Curr Drug Deliv 2015;12:139–56.
  • Sudhakar Y, Kuotsu K, Bandyopadhyay AK. Buccal bioadhesive drug delivery - A promising option for orally less efficient drugs. J Control Release 2006;114:15–40.
  • Morales JO, McConville JT. Manufacture and characterization of mucoadhesive buccal films. Eur J Pharm Biopharm 2011;77:187–99.
  • Silva BMA, Borges AF, Silva C, et al. Mucoadhesive oral films: the potential for unmet needs. Int J Pharm 2015;494:537–51.
  • Birudaraj R, Mahalingam R, Li X, et al. Advances in buccal drug delivery. Crit Rev Ther Drug Carrier Syst 2005;22:295–330.
  • Patel VF, Liu F, Brown MB. Advances in oral transmucosal drug delivery. J Control Release 2011;153:106–16.
  • Burak T, Tolga D, Ayhan E. Effectiveness of sublingual nitroglycerin before puncture compared with conventional intra-arterial nitroglycerin in transradial procedures: a randomized trial. Cardiovasc Revasc Med 2015;16:391–6.
  • Parodi B, Russo E, Caviglioli G, et al. Development and characterization of a buccoadhesive dosage form of oxycodone hydrochloride. Drug Dev Ind Pharm 1996;22:445–50.
  • Pliszczak D, Bourgeois S, Bordes C, et al. Improvement of an encapsulation process for the preparation of pro- and prebiotics-loaded bioadhesive microparticles by using experimental design. Eur J Pharm Sci 2011;44:83–92.
  • Saha NR, Sarkar G, Roy I, et al. Studies on methylcellulose/pectin/montmorillonite nanocomposite films and their application possibilities. Carbohydr Polym 2016;136:1218–27.
  • EC. Commission Implementing Decision, No C(2015) 2617. Brussels: European Commission; 2015.
  • Leppert W. Role of oxycodone and oxycodone/naloxone in cancer pain management. Pharmacol Rep 2010;62:578–91.
  • Pergolizzi JV, Jr, Seow-Choen F, Wexner SD, et al. Perspectives on intravenous oxycodone for control of postoperative pain. Pain Pract 2016;16:924–34.
  • Attal N, Cruccu G, Baron R, et al. EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revision. Eur J Neurol 2010;17:1113–e88.
  • Parodi B, Russo E, Caviglioli G, et al. Buccoadhesive oxycodone hydrochloride disks: Plasma pharmacokinetics in healthy volunteers and clinical study. Eur J Pharm Biopharm 1997;44:137–42.
  • Visser JC, Woerdenbag HJ, Crediet S, et al. Orodispersible films in individualized pharmacotherapy: The development of a formulation for pharmacy preparations. Int J Pharm 2015;478:155–63.
  • Meher JG, Tarai M, Yadav NP, et al. Development and characterization of cellulose-polymethacrylate mucoadhesive film for buccal delivery of carvedilol. Carbohydr Polym 2013;96:172–80.
  • Bruschi ML, Jones DS, Panzeri H, et al. Semisolid systems containing propolis for the treatment of periodontal disease: in vitro release kinetics, syringeability, rheological, textural, and mucoadhesive properties. J Pharm Sci 2007;96:2074–89.
  • Perioli L, Pagano C. Preformulation studies of mucoadhesive tablets for carbamazepine sublingual administration. Colloid Surface B 2013;102:915–22.
  • Schmidt W, inventor. Process for producing an administration or dosage form for drugs, reagents or other active ingredients. US Patent 4849246. 1989.
  • Yang R, Fuisz R, Myers G, et al. inventors. Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom. US Patent 7425292. 2008.
  • Perumal VA, Govender T, Lutchman D, et al. Investigating a new approach to film casting for enhanced drug content uniformity in polymeric films. Drug Dev Ind Pharm 2008;34:1036–47.
  • Krampe R, Visser JC, Frijlink HW, et al. Oromucosal film preparations: points to consider for patient centricity and manufacturing processes. Expert Opin Drug Deliv 2015;13:493–506.
  • Susarla R, Afolabi A, Patel D, et al. Novel use of superdisintegrants as viscosity enhancing agents in biocompatible polymer films containing griseofulvin nanoparticles. Powder Technol 2015;285:25–33.
  • Hagesaether E, Hiorth M, Sande SA. Mucoadhesion and drug permeability of free mixed films of pectin and chitosan: An in vitro and ex vivo study. Eur J Pharm Biopharm 2009;71:325–31.
  • European Pharmacopoeia. 8th ed; 2014.
  • Aulton ME, Abdul-Razzak MH, Hogan JE. The mechanical properties of hydroxyl propyl methyl cellulose films derived from aqueous systems: the influence of solid inclusions. Drug Dev Ind Pharm 1981;7:649–68.
  • Boateng JS, Pawar HV, Tetteh J. Polyox and carrageenan based composite film dressing containing anti-microbial and anti-inflammatory drugs for effective wound healing. Int J Pharm 2013;441:181–91.
  • Liew KB, Tan YTF, Peh K-K. Effect of polymer, plasticizer and filler on orally disintegrating film. Drug Dev Ind Pharm 2014;40:110–19.
  • Boateng J, Stevens H, Eccleston G. Development and mechanical characterization of solvent-cast polymeric films as potential drug delivery systems to mucosal surfaces. Drug Dev Ind Pharm 2009;35:986–96.
  • Florence AT. Neglected diseases, neglected technologies, neglected patients?. Int J Pharm 2008;350:1–2.
  • Visser JC, Woerdenbag HJ, Hanff LM, et al. Personalized medicine in pediatrics: the clinical potential of orodispersible films. AAPS PharmSciTech 2016. [Epub ahead of print]. doi: 10.1208/s12249-016-0515-1.

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