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Research Article

Effects of surface charge of low molecular weight heparin-modified cationic liposomes on drug efficacy and toxicity

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Pages 1163-1172 | Received 30 Aug 2016, Accepted 23 Feb 2017, Published online: 21 Mar 2017

References

  • Kumari P, Ghosh B, Biswas S. Nanocarriers for cancer-targeted drug delivery. J Drug Target 2015;24:179–91.
  • Li XT, He ML, Zhou ZY, et al. The antitumor activity of PNA modified vinblastine cationic liposomes on Lewis lung tumor cells: in vitro and in vivo evaluation. Int J Pharm 2015;487:223–33.
  • Streith S, Eichhorn ME, Sauer B, et al. Neovascular targeting chemotherapy: Encapsulation of paclitaxel in cationic liposomes impairs functional tumor microvasculature. Int J Cancer 2004;110:117–24.
  • Malhotra M, Kulamarva A, Sebak S, et al. Ultrafine chitosan nanoparticles as an efficient nucleic acid delivery system targeting neuronal cells. Drug Dev Ind Pharm Res 2009;35:719–26.
  • Campbell RB, Ying B, Kuesters GM, Hemphill R. Fighting cancer: from the bench to bedside using second generation cationic liposomal therapeutics. J Pharm Sci 2009;98:411–29.
  • Ran S, Downes A, Thorpe PE. Increased exposure of anionic phospholipids on the surface of tumor blood vessels. Cancer Res 2002;62:6132–40.
  • Augustin HG, Kozian DH, Johnson RC. Differentiation of endothelial cells: analysis of the constitutive and activated endothelial cell phenotypes. Bioessays 1994;16:901–6.
  • Torchilin VP. Fluorescence microscopy to follow the targeting of liposomes and micelles to cells and their intracellular fate. Adv Drug Deliv Rev 2005;57:95–109.
  • Han HD, Byeon Y, Jeon HN, Shin BC. Enhanced localization of anticancer drug in tumor tissue using polyethylenimine-conjugated cationic liposomes. Nanoscale Res Lett 2014;9:209.
  • Simberg D, Weisman S, Talmon Y, et al. The role of organ vascularization and lipoplex-serum initial contact in intravenous murine lipofection. J Biol Chem 2003;278:39858–65.
  • Freimark BD, Blezinger HP, Florack VJ, et al. Cationic lipids enhance cytokine and cell influx levels in the lung following administration of plasmid: cationic lipid complexes. J Immunol 1998;160:4580–6.
  • Dokka S, Toledo D, Shi XG, et al. Oxygen radical-mediated pulmonary toxicity induced by some cationic liposomes. Pharm Res 2000;17:521–5.
  • Zylberberg C, Matosevic S. Pharmaceutical liposomal drug delivery: a review of new delivery systems and a look at the regulatory landscape. Deliv 2016;23:3319–29.
  • Klibanov AL, Maruyama K, Beckerleg AM, et al. Activity of amphipathic poly(ethylene glycol) 5000 to prolong the circulation time of liposomes depends on the liposome size and is unfavorable for immunoliposome binding to target. Biochim Biophys Acta 1991;1062:142–8.
  • Allen C, Dos Santos N, Gallagher R, et al. Controlling the physical behavior and biological performance of liposome formulations through use of surface grafted poly(ethylene glycol). Biosci Rep 2002;22:225–50.
  • Liu ZD, Zhao HN, Shu LX, et al. Preparation and evaluation of Baicalin-loaded cationic solid lipid nanoparticles conjugated with OX26 for improved delivery across the BBB. Drug Dev Ind Pharm Res 2015;41:353–61.
  • Levchenko TS, Rammohan R, Lukyanov AN, et al. Liposome clearance in mice: the effect of a separate and combined presence of surface charge and polymer coating. Int J Pharm 2002;240:95–102.
  • Borsig L. Antimetastatic activities of heparins and modified heparins. Experimental evidence. Thromb Res 2010;125:S66–71.
  • Park K, Kim YS, Lee GY, et al. Tumor endothelial cell targeted cyclic RGD-modified heparin derivative: inhibition of angiogenesis and tumor growth. Pharm Res 2008;25:2786–98.
  • Bae KH, Mok H, Park TG. Synthesis, characterization, and intracellular delivery of reducible heparin nanogels for apoptotic cell death. Biomaterials 2008;29:3376–83.
  • Chen Y, Peng JQ, Han MM, et al. A low-molecular-weight heparin-coated doxorubicin-liposome for the prevention of melanoma metastasis. J Drug Target 2015;23:335–46.
  • Maheshwari RK, Singh AK, Gaddipati J, Srimal RC. Multiple biological activities of curcumin: a short review. Life Sci 2006;78:2081–7.
  • Parvathy KS, Negi PS, Srinivas P. Antioxidant, antimutagenic and antibacterial activities of curcumin-beta-diglucoside. Food Chem 2009;115:265–71.
  • Chaurasia S, Chaubey P, Patel RR, et al. Curcumin-polymeric nanoparticles against colon-26 tumor-bearing mice: cytotoxicity, pharmacokinetic and anticancer efficacy studies. Drug Dev Ind Pharm Res 2016;42:694–700.
  • Bisht S, Feldmann G, Soni S, et al. Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): a novel strategy for human cancer therapy. J Nanobiotechnol 2007;5:3.
  • Maiti K, Mukherjee K, Gantait A, et al. Curcumin-phospholipid complex: preparation, therapeutic evaluation and pharmacokinetic study in rats. Int J Pharm 2007;330:155–63.
  • Zhang L, Lu CT, Li WF, et al. Physical characterization and cellular uptake of propylene glycol liposomes in vitro. Drug Dev Ind Pharm Res 2012;38:365–71.
  • Han HD, Lee A, Song CK, et al. In vivo distribution and antitumor activity of heparin-stabilized doxorubicin-loaded liposomes. Int J Pharm 2006;313:181–8.
  • Mourtas S, Duraj S, Fotopoulou S, Antimisiaris SG. Integrity of liposomes in presence of various formulation excipients, when dispersed in aqueous media and in hydrogels. Colloids Surf B Biointerfaces 2008;61:270–6.
  • Reimer DL, Kong S, Monck M, et al. Liposomal lipid and plasmid DNA delivery to B16/BL6 tumors after intraperitoneal administration of cationic liposome DNA aggregates. J Pharmacol Exp Ther 1999;289:807–15.
  • Tian J, Han M, Wang Y, et al. Reduction responsive modification induced higher efficiency for attenuation of tumor metastasis of low molecular weight heparin functionalized liposomes. RSC Advances 2016;6:49250–62.
  • Kondo T, Tomizawa M. Mechanism of hemolysis by cationic surface-active agents. J Pharm Sci 1969;58:1378–81.
  • Han MH, Chen J, Wang J, et al. Blood compatibility of polyamidoamine dendrimers and erythrocyte protection. J Biomed Nanotechnol 2010;6:82–92.
  • Ci TY, Chen L, Yu L, Ding JD. Tumor regression achieved by encapsulating a moderately soluble drug into a polymeric thermogel. Sci Rep 2014;4:5473.
  • Wang JG, Zhang JB, Zhang CJ, et al. In situ proteomic profiling of curcumin targets in HCT116 colon cancer cell line. Sci Rep 2016;6:8.
  • Dijkstra J, Van Galen M, Scherphof G. Influence of liposome charge on the association of liposomes with Kupffer cells in vitro. Effects of divalent cations and competition with latex particles. Biochim Biophys Acta 1985;813:287–97.
  • Martin FJ, Macdonald RC. Lipid vesicle-cell interactions. I. Hemagglutination and hemolysis. J Cell Biol 1976;70:494–505.
  • Campbell RB, Fukumura D, Brown EB, et al. Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors. Cancer Res 2002;62:6831–6.
  • Thurston G, Mclean JW, Rizen M, et al. Cationic liposomes target angiogenic endothelial cells in tumors and chronic inflammation in mice. J Clin Invest 1998;101:1401–13.
  • Hu TT, Cao H, Yang CL, et al. LHD-Modified mechanism-based liposome coencapsulation of mitoxantrone and prednisolone using novel lipid bilayer fusion for tissue-specific colocalization and synergistic antitumor effects. ACS Appl Mater Interfaces 2016;8:6586–601.
  • Mousa SA, Linhardt R, Francis JL, Amirkhosravi A. Anti-metastatic effect of a non-anticoagulant low-molecular-weight heparin versus the standard low-molecular-weight heparin, enoxaparin. Thromb Haemost 2006;96:816–21.
  • Irimura T, Nakajima M, Nicolson GL. Chemically modified heparins as inhibitors of heparan sulfate specific endo-beta-glucuronidase (heparanase) of metastatic melanoma cells. Biochemistry 1986;25:5322–8.

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