211
Views
6
CrossRef citations to date
0
Altmetric
Research Articles

Development and optimization of drug-loaded nanoemulsion system by phase inversion temperature (PIT) method using Box–Behnken design

, , &
Pages 977-989 | Received 27 Dec 2020, Accepted 04 Jun 2021, Published online: 02 Aug 2021

References

  • Karthik P, Ezhilarasi PN, Anandharamakrishnan C. Challenges associated in stability of food grade nanoemulsions. Crit Rev Food Sci Nutr. 2017;57(7):1435–1450.
  • Dokania S, Joshi AK. Self-microemulsifying drug delivery system (SMEDDS) – challenges and road ahead. Drug Deliv. 2015;22(6):675–690.
  • Rehman FU, Shah KU, Shah SU, et al. From nanoemulsions to self-nanoemulsions, with recent advances in self-nanoemulsifying drug delivery systems (SNEDDS). Expert Opin Drug Deliv. 2016;5247:1–16.
  • Agrawal S, Giri TK, Tripathi DK, et al. A review on novel therapeutic strategies for the enhancement of solubility for hydrophobic drugs through lipid and surfactant based self micro emulsifying drug delivery system: a novel approach. Am J Drug Discov Dev. 2012;2(4):143–183.
  • Maali A, Mosavian MTH. Preparation and application of nanoemulsions in the last decade (2000–2010). J Dispers Sci Technol. 2013;34(1):92–105.
  • Alshehri S, Imam SS, Hussain A, et al. Flufenamic acid-loaded self-nanoemulsifying drug delivery system for oral delivery: from formulation statistical optimization to preclinical anti-inflammatory assessment. J Oleo Sci. 2020;69(10):1257–1271.
  • Kumar M, Bishnoi RS, Shukla AK, et al. Techniques for formulation of nanoemulsion drug delivery system: a review. Prev Nutr Food Sci. 2019;24(3):225–234.
  • Chatterjee B, Hamed Almurisi S, Ahmed Mahdi Dukhan A, et al. Controversies with self-emulsifying drug delivery system from pharmacokinetic point of view. Drug Deliv. 2016;23(9):3639–3652.
  • Rai VK, Mishra N, Yadav KS, et al. Nanoemulsion as pharmaceutical carrier for dermal and transdermal drug delivery: formulation development, stability issues, basic considerations and applications. J Control Release. 2018;270:203–225.
  • de Oca-Ávalos JMM, Candal RJ, Herrera ML. Nanoemulsions: stability and physical properties. Curr Opin Food Sci. 2017;16:1–6.
  • Qadir A, Faiyazuddin MD, Talib Hussain MD, et al. Critical steps and energetics involved in a successful development of a stable nanoemulsion. J Mol Liq. 2016;214:7–18.
  • Chuesiang P, Siripatrawan U, Sanguandeekul R, et al. Optimization of cinnamon oil nanoemulsions using phase inversion temperature method: impact of oil phase composition and surfactant concentration. J Colloid Interface Sci. 2018;514:208–216.
  • Mashhadi S, Javadian H, Tyagi I, et al. The effect of Na2SO4 concentration in aqueous phase on the phase inversion temperature of lemon oil in water nano-emulsions. J Mol Liq. 2016;215:454–460.
  • Jintapattanakit A, Hasan HM, Junyaprasert VB. Vegetable oil-based nanoemulsions containing curcuminoids: formation optimization by phase inversion temperature method. J Drug Deliv Sci Technol. 2018;44:289–297.
  • Ren G, Sun Z, Wang Z, et al. Nanoemulsion formation by the phase inversion temperature method using polyoxypropylene surfactants. J Colloid Interface Sci. 2019;540:177–184.
  • Solans C, Sole I. Nano-emulsions: formation by low-energy methods. Curr Opin Colloid Interface Sci. 2012;17(5):246–254.
  • Moreira de Morais J, David Henrique dos Santos O, Delicato T, et al. Physicochemical characterization of canola oil/water nano‐emulsions obtained by determination of required HLB number and emulsion phase inversion methods. J Dispers Sci Technol. 2006;27(1):109–115.
  • Kazama I. Roles of lymphocyte Kv1.3-channels in the pathogenesis of renal diseases and novel therapeutic implications of targeting the channels. Mediators Inflamm. 2015;2015:1–12.
  • Suzuki H, Miyamoto N, Masada T, et al. Solid dispersions of benidipine hydrochloride. I. preparations using different solvent systems and dissolution properties. Chem Pharm Bull. 1996;44(2):364–371.
  • Yao K, Nagashima K, Miki H. Pharmacological, pharmacokinetic, and clinical properties of benidipine hydrochloride, a novel, long-acting calcium channel blocker. J Pharmacol Sci. 2006;100(4):243–261.
  • Saberi AH, Fang Y, McClements DJ. Effect of glycerol on formation, stability, and properties of vitamin-E enriched nanoemulsions produced using spontaneous emulsification. J Colloid Interface Sci. 2013;411:105–113.
  • Subramanian N, Sharavanan SP, Chandrasekar P, et al. Lacidipine self-nanoemulsifying drug delivery system for the enhancement of oral bioavailability. Arch Pharm Res. 2016;39(4):481–491.
  • Mohd AB, Sanka K, Bandi S, et al. Solid self-nanoemulsifying drug delivery system (S-SNEDDS) for oral delivery of glimepiride: development and antidiabetic activity in albino rabbits. Drug Deliv. 2015;22(4):499–508.
  • Venkata Ramana Rao S, Shao J. Self-nanoemulsifying drug delivery systems (SNEDDS) for oral delivery of protein drugs: I formulation development. Int J Pharm. 2008;362(1–2):2–9.
  • Gurram A, Deshpande P, Kar P, et al. Role of components in the formation of self-microemulsifying drug delivery systems. Indian J Pharm Sci. 2015;77(3):249–257.
  • Zhao T, Maniglio D, Chen J, et al. Design and optimization of self-nanoemulsifying formulations for lipophilic drugs. Nanotechnology. 2015;26(12):125102–125107.
  • Komaiko JS, Mcclements DJ. Formation of food-grade nanoemulsions using low-energy preparation methods: A review of available methods. Compr Rev Food Sci Food Saf. 2016;15(2):331–352.
  • Anton N, Vandamme TF. The universality of low-energy nano-emulsification. Int J Pharm. 2009;377(1–2):142–147.
  • Marasini N, Yan YD, Poudel BK, et al. Development and optimization of self-nanoemulsifying drug delivery system with enhanced bioavailability by Box–Behnken design and desirability function. J Pharm Sci. 2012;101(12):4584–4596.
  • Kotta S, Khan AW, Ansari SH, et al. Formulation of nanoemulsion: a comparison between phase inversion composition method and high-pressure homogenization method. Drug Deliv. 2015;22(4):455–466.
  • Aqil M, Kamran M, Ahad A, et al. Development of clove oil based nanoemulsion of olmesartan for transdermal delivery: Box–Behnken design optimization and pharmacokinetic evaluation. J Mol Liq. 2016;214:238–248.
  • Wu XG, Li G, Gao YL. Optimization of the preparation of nalmefene-loaded sustained-release microspheres using central composite design. Chem Pharm Bull. 2006;54(7):977–981.
  • Dash RN, Mohammed H, Humaira T, et al. Design, optimization and evaluation of glipizide solid self-nanoemulsifying drug delivery for enhanced solubility and dissolution. Saudi Pharm J. 2015;23(5):528–540.
  • Khan AW, Kotta S, Ansari SH, et al. Self-nanoemulsifying drug delivery system (SNEDDS) of the poorly water-soluble grapefruit flavonoid Naringenin: design, characterization, in vitro and in vivo evaluation. Drug Deliv. 2015;22(4):552–561.
  • McClements DJ, Rao J. Food-Grade nanoemulsions: formulation, fabrication, properties, performance, biological fate, and potential toxicity. Crit Rev Food Sci Nutr. 2011;51(4):285–330.
  • Park BG, Park IJ, Han JS, et al. Characterization of optical properties in water-in-oil emulsion. J Dispers Sci Technol. 2013;34(4):560–565.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.