Formulation and optimization of silymarin-encapsulated binary micelles for enhanced amyloid disaggregation activity

References

• Ahmad Z, Shah A, Siddiq M, et al. Polymeric micelles as drug delivery vehicles. RSC Adv. 2014;4(33):17028–17038.
   Web of Science ®Google Scholar
• Alexandridis P, Hatton A. T poly(ethylene oxide)poly(propylene oxide)poly(ethylene oxide) block copolymer surfactants in aqueous solutions and at interfaces: thermodynamics, structure, dynamics, and modeling. Colloids Surf A: Physicochem Eng Asp. 1995;96(1–2):1–46.
   Web of Science ®Google Scholar
• Anthony P, Lowe KC, Davey MR, et al. Enhanced post-thaw viability of cryopreserved cells by oxygenated perfluorocarbon or pluronic® F-68. Artif Cells Blood Substit Immobil Biotechnol. 1998;26(1):27–33.
   PubMed Web of Science ®Google Scholar
• Baig MS, Ahad A, Aslam M, et al. Application of Box–Behnken design for preparation of levofloxacin-loaded stearic acid solid lipid nanoparticles for ocular delivery: optimization, in vitro release, ocular tolerance, and antibacterial activity. Int J Biol Macromol. 2016;85:258–270.
   PubMed Web of Science ®Google Scholar
• Barrow CJ, Yasuda A, Kenny PTM, et al. Solution conformations and aggregational properties of synthetic amyloid β-peptides of alzheimer’s disease. Analysis of circular dichroism spectra. J Mol Biol. 1992;225(4):1075–1093.
   PubMed Web of Science ®Google Scholar
• Bastakoti BP, Ishihara S, Leo SY, et al. Polymeric micelle assembly for preparation of large-sized mesoporous metal oxides with various compositions. Langmuir. 2014;30(2):651–659.
   PubMed Web of Science ®Google Scholar
• Benilova I, Karran E, Strooper D. B. The toxic Aβ oligomer and Alzheimer’s disease: an emperor in need of clothes. Nat Neurosci. 2012;15(3):349–357.
   PubMed Web of Science ®Google Scholar
• Zhang Z, Tan S, Feng SS. Vitamin E TPGS as a molecular biomaterial for drug delivery. Biomaterials. 2012;33(19):4889–4906.
   PubMed Web of Science ®Google Scholar
• Choi JS, Cho NH, Kim DH, et al. Comparison of paclitaxel solid dispersion and polymeric micelles for improved oral bioavailability and in vitro anti-cancer effects. Mater Sci Eng C Mater Biol Appl. 2019;100:247–259.
   PubMed Web of Science ®Google Scholar
• Dian L, Yu E, Chen X, et al. Enhancing oral bioavailability of quercetin using novel soluplus polymeric micelles. Nanoscale Res Lett. 2014;9(1):1.
   PubMed Web of Science ®Google Scholar
• Ding P, Chen Y, Cao G, et al. Solutol®HS15 + pluronicF127 and solutol®HS15 + pluronicL61 mixed micelle systems for oral delivery of genistein. Drug Des Dev Ther. 2019;13:1947–1956.
   PubMed Web of Science ®Google Scholar
• Dwivedi P, Khatik R, Khandelwal K, et al. Preparation and characterization of solid lipid nanoparticles of antimalarial drug arteether for oral administration. J Biomater Tissue Eng. 2014;4(2):133–137.
   Web of Science ®Google Scholar
• Dizaj SM, Lotfipour F, Barzegar-Jalali M, et al. Box–Behnken experimental design for preparation and optimization of ciprofloxacin hydrochloride-loaded CaCO3 nanoparticles. J Drug Deliv Sci Technol. 2015; 29:125–131.
   Web of Science ®Google Scholar
• Fattahi A, Golozar MA, Varshosaz J, et al. Preparation and characterization of micelles of oligomeric chitosan linked to all-trans retinoic acid. Carbohydr Polym. 2012;87(2):1176–1184.
   Web of Science ®Google Scholar
• Fernández K, Aburto J, Von Plessing C, et al. Factorial design optimization and characterization of poly-lactic acid (PLA) nanoparticle formation for the delivery of grape extracts. Food Chem. 2016;207:75–85.
   PubMed Web of Science ®Google Scholar
• Hu L, Gao W, Zhang J, et al. Development of a new coenzyme Q10 (CoQ10) mixed micelle with high stability: based on the thermodynamics of cloud point. J Mol Liq. 2017;242:16–23.
   Web of Science ®Google Scholar
• Jindal N, Mehta SK. Nevirapine loaded poloxamer 407/pluronic P123 mixed micelles: optimization of formulation and in vitro evaluation. Colloids Surf B Biointerfaces. 2015;129:100–106.
   PubMed Web of Science ®Google Scholar
• Ke Z, Yang L, Wu H, et al. Evaluation of in vitro and in vivo antitumor effects of gambogic acid-loaded layer-by-layer self-assembled micelles. Int J Pharm. 2018;545(1–2):306–317.
   PubMed Web of Science ®Google Scholar
• Lian R, Lu Y, Qi J, et al. Silymarin glyceryl monooleate/poloxamer 407 liquid crystalline matrices: Physical characterization and enhanced oral bioavailability. AAPS PharmSciTech. 2011;12(4):1234–1240.
   PubMed Web of Science ®Google Scholar
• Liao YH, Chang YJ, Yoshiike Y, et al. Negatively charged gold nanoparticles inhibit Alzheimer's amyloid-β fibrillization, induce fibril dissociation, and mitigate neurotoxicity. Small. 2012;8(23):3631–3639.
   PubMed Web of Science ®Google Scholar
• Liu H, Xie B, Dong X, et al. Negatively charged hydrophobic nanoparticles inhibit amyloid β-protein fibrillation: the presence of an optimal charge density. React Funct Polym. 2016;103:108–116.
   Web of Science ®Google Scholar
• Muley MM, Thakare VN, Patil RR, et al. Silymarin improves the behavioural, biochemical and histoarchitecture alterations in focal ischemic rats: a comparative evaluation with piracetam and protocatachuic acid. Pharmacol Biochem Behav. 2012;102(2):286–293.
   PubMed Web of Science ®Google Scholar
• Ravanfar R, Tamaddon AM, Niakousari M, et al. Moein MR preservation of anthocyanins in solid lipid nanoparticles: optimization of a microemulsion dilution method using the Placket-Burman and Box–Behnken designs. Food Chem. 2016;199:573–580.
   PubMed Web of Science ®Google Scholar
• Reina M, Martínez A. Silybin and 2,3-dehydrosilybin flavonolignans as free radical scavengers. J Phys Chem B. 2015;119(35):11597–11606.
   PubMed Web of Science ®Google Scholar
• Sciacca MFM, Romanucci V, Zarrelli A, et al. Inhibition of Aβ amyloid growth and toxicity by silybins: the crucial role of stereochemistry. ACS Chem Neurosci. 2017;8(8):1767–1778.
   PubMed Web of Science ®Google Scholar
• Sezgin Z, Yüksel N, Baykara T. Preparation and characterization of polymeric micelles for solubilization of poorly soluble anticancer drugs. Eur J Pharm Biopharm. 2006;64(3):261–268.
   PubMed Web of Science ®Google Scholar
• Shen H, Liu Y, Zhang H, et al. Enhancing the oral bioavailability of baicalein via Solutol® HS15 and Poloxamer 188 mixed micelles system. J Pharm Pharmacol. 2019;71(5):765–773.
   PubMed Web of Science ®Google Scholar
• Singh A, Kumar A, Verma RK, et al. Shukla R silymarin encapsulated nanoliquid crystals for improved activity against beta amyloid induced cytotoxicity. Int J Biol Macromol. 2020;149:1198–1206.
   PubMed Web of Science ®Google Scholar
• Singh A, Vaishagya K, K. Verma R, et al. Temperature/pH-Triggered PNIPAM-Based smart nanogel system loaded with anastrozole delivery for application in cancer chemotherapy. AAPS PharmSciTech. 2019;20(5):1–14.
   Web of Science ®Google Scholar
• Stathopulos PB, Scholz GA, Hwang Y-M, et al. Sonication of proteins causes formation of aggregates that resemble amyloid. Protein Sci. 2004;13(11):3017–3027.
   PubMed Web of Science ®Google Scholar
• Sun F, Jaspers TCC, van Hasselt PM, et al. A mixed micelle formulation for oral delivery of vitamin K. Pharm Res. 2016;33(9):2168–2179.
   PubMed Web of Science ®Google Scholar
• Trouillas P, Marsal P, Svobodová A, et al. Mechanism of the antioxidant action of silybin and 2,3-dehydrosilybin flavonolignans: a joint experimental and theoretical study . J Phys Chem A. 2008;112(5):1054–1063.
   PubMed Web of Science ®Google Scholar
• Murata NM, Urakami KM, Zawa YO, et al. Silymarin attenuated the amyloid β plaque burden and improved behavioral abnormalities in an Alzheimer's disease mouse model. Biosci Biotechnol Biochem. 2010;74(11):2299–2306.
   PubMed Web of Science ®Google Scholar
• Vozza G, Danish M, Byrne HJ, et al. Application of Box–Behnken experimental design for the formulation and optimisation of selenomethionine-loaded chitosan nanoparticles coated with zein for oral delivery. Int J Pharm. 2018;551(1–2):257–269.
   PubMed Web of Science ®Google Scholar
• Wei Z, Hao J, Yuan S, et al. Paclitaxel-loaded pluronic P123/F127 mixed polymeric micelles: formulation, optimization and in vitro characterization. Int J Pharm. 2009;376(1–2):176–185.
   PubMed Web of Science ®Google Scholar
• Ye F, Guo H, Zhang H, et al. Polymeric micelle-templated synthesis of hydroxyapatite hollow nanoparticles for a drug delivery system. Acta Biomater. 2010;6(6):2212–2218.
   PubMed Web of Science ®Google Scholar
• Yin F, Liu J, Ji X, et al. Silibinin: a novel inhibitor of Aβ aggregation. Neurochem Int. 2011;58(3):399–403.
   PubMed Web of Science ®Google Scholar
• Younes NF, Abdel-Halim SA, Elassasy AI. Solutol HS15 based binary mixed micelles with penetration enhancers for augmented corneal delivery of sertaconazole nitrate: optimization, in vitro, ex vivo and in vivo characterization. Drug Deliv. 2018;25(1):1706–1717.
   PubMed Web of Science ®Google Scholar
• Zhai Y, Guo S, Liu C, et al. Preparation and in vitro evaluation of apigenin-loaded polymeric micelles. Colloids Surf A: Physicochem Eng Asp. 2013;429:24–30.
   Web of Science ®Google Scholar
• Zhang W, Shi Y, Chen Y, et al. Multifunctional pluronic P123/F127 mixed polymeric micelles loaded with paclitaxel for the treatment of multidrug resistant tumors. Biomaterials. 2011;32(11):2894–2906.
   PubMed Web of Science ®Google Scholar
• Zhao X, Deng Y, Zhang Y, et al. Silymarin nanoparticles through emulsion solvent evaporation method for oral delivery with high antioxidant activities, bioavailability, and absorption in the liver. RSC Adv. 2016;6(95):93137–93146.
   Web of Science ®Google Scholar