187
Views
0
CrossRef citations to date
0
Altmetric
Research Articles

Visualizing fluid transport inside orally disintegrating tablets and changes in tablets using real-time X-ray radiography and X-ray computed tomography

, , , , , , & show all
Pages 301-309 | Received 15 Feb 2022, Accepted 25 Jul 2022, Published online: 12 Aug 2022

References

  • Pabari RM, Ramtoola Z. Effect of a disintegration mechanism on wetting, water absorption, and disintegration time of orodispersible tablets. J Young Pharm. 2012;4:157–163.
  • Markl D, Wang P, Ridgway C, et al. Resolving the rapid water absorption of porous functionalised calcium carbonate powder compacts by terahertz pulsed imaging. Chem Eng Res Des. 2018;132:1082–1090.
  • Harbir K. Processing technologies for pharmaceutical tablets: a review. Int Res J Pharm. 2012;3:20–23.
  • Markl D, Zeitler JA. A review of disintegration mechanisms and measurement techniques. Pharm Res. 2017;34(5):890–917.
  • Tsushima Y. New molded tablet and corresponding novel method for production. J Jpn Soc Pharm Mach & Eng. 2001;10(4):5–17.
  • Vaitukaitis P, Maggiolo D, Remmelgas J, et al. Water transport and absorption in pharmaceutical tablets – a numerical study. Meccanica. 2020;55:421–433.
  • Suzuki T, Kurano T, Kanazawa T, et al. Establishment of a novel method to evaluate water permeation rates by combining the dynamic contact angle and thermographic approach: significance of disintegration properties of orally disintegrating tablets. Yakugaku Zasshi. 2020;140(8):1071–1080.
  • Zhang Q, Gladden LF, Avalle P, et al. Terahertz pulsed imaging and magnetic resonance imaging as tools to probe formulation stability. Pharmaceutics. 2013;5(4):591–608.
  • Okabayashi T, Ishikawa S, Hiramura T, et al. [3D structure analysis of wicking and disintegration process in rapid disintegration of orally disintegrating tablet (OD tablet) using co-processed excipient for OD tablet]. SPring-8 Section A: Scientific Res Rep. 2018;6(2):215–218.
  • Charest K, Mak-Jurkauskas ML, Cinicola D, et al. Fused deposition modeling provides solution for magnetic resonance imaging of solid dosage form by advancing design quickly from prototype to final product. J Lab Autom. 2013;18(1):63–68.
  • Kulinowski P, Hudy W, Mendyk A, et al. The relationship between the evolution of an internal structure and drug dissolution from controlled-release matrix tablets. AAPS PharmSciTech. 2016;17(3):735–742.
  • Yin X, Li H, Guo Z, et al. Quantification of swelling and erosion in the controlled release of a poorly water-soluble drug using synchrotron X-ray computed microtomography. Aaps J. 2013;15(4):1025–1034.
  • Yassin S, Su K, Lin H, et al. Diffusion and swelling measurements in pharmaceutical powder compacts using terahertz pulsed imaging. J Pharm Sci. 2015;104(5):1658–1667.
  • Goldsack DE, Franchetto R. The viscosity of concentrated electrolyte solutions. I. Concentration dependence at fixed temperature. Can J Chem. 1977;55(6):1062.
  • Rasband WS. ImageJ. (U. S. National Institutes of Health, Bethesda, MD, 1997-2018). Available from: https://imagej.nih.gov/ij/.
  • Al-Sharabi M, Markl D, Mudley T, et al. Simultaneous investigation of the liquid transport and swelling performance during tablet disintegration. Int J Pharm. 2020;584:119380.
  • Sawayama S, Kawabata A, Okabe M, et al. Viscosities of carrageean aqueous solution and physical properties of carrageenan-water gels. J Agric Chem. 1978;52:409–415.
  • Rashid I, Daraghmeh N, Al-Remawi M, et al. Characterization of the impact of magnesium stearate lubrication on the tableting properties of chitin-Mg silicate as a superdisintegrating binder when compared to Avicel® 200. Powder Technology. 2010;203:609–619.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.