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Articles

Conjugated Linoleic Acid and Disease Prevention: A Review of Current Knowledge

, MSc, RD, FDC
Pages 111S-118S | Received 01 Nov 1999, Published online: 14 Jun 2013

REFERENCES

  • Erickson KL, Hubbard NE: Dietary fat and tumor metastasis. Nutr Rev 48: 6–14, 1990.
  • Welsch CW: Relationship between dietary fat and experimental mammary tumorigenesis: A review and critique. Cancer Res Suppl 52: 1040s–1048s, 1992.
  • Welsch CW: Interrelationship between dietary lipids and calories and experimental mammary gland tumorigenesis. Cancer 74: 1055–1062, 1994.
  • Kondo Y, Homma Y, Aso Y, Kakizoe T: Promotional effect of two-generation exposure to a high-fat diet on prostate carcinogenesis in ACI/Seg rats. Cancer Res 23: 6129–6132, 1994.
  • Carroll KK, Hopkins GJ: Dietary polyunsaturated fat versus saturated fat in relation to mammary carcinogenesis. Lipids 14: 155–158, 1979.
  • Ip C, Carter CA, Ip MM: Requirements of essential fatty acid for mammary tumorigenesis in the rat. Cancer Res 45: 1997–2001, 1985.
  • Decker EA: The role of phenolics, conjugated linoleic acid, carnosine, and pyrroloquinoline quinone as nonessential dietary antioxidants. Nutr Rev 53: 49–58, 1995.
  • Ip C, Scimeca JA, Thompson HJ: Conjugated linoleic acid. A powerful anticarcinogen from animal fat sources. Cancer 74(3 Suppl): 1050–1054, 1994b.
  • Buttriss J, Hiddink G: Role of conjugated Linoleic Acid (CLA) in health and physiological processes. Utrecht Group Workshop, 1996.
  • Parodi PW: Cow’s milk fat components as potential anticarcinogenic agents. J Nutr 127: 1055–1060, 1997.
  • van den Berg JJ, Cook NE, Tribble DL: Reinvestigation of the antioxidant properties of conjugated linoleic acid. Lipids 30: 599–605, 1995.
  • Ha YL, Grimm NK, Pariza MW: Newly recognized anticarcinogenic fatty acids: identification and quantification in natural and processed cheeses. J Agric Food Chem 37: 75–81, 1989.
  • Yurawecz MP, Hood JK, Mossoba MM, Roach JA, Ku Y: Furan fatty acids determined as oxidation products of conjugated octadecadienoic acid. Lipids 30: 595–598, 1995.
  • Shantha NC, Decker EA: Conjugated linoleic acid concentrations in processed cheese containing hydrogen donors, iron and dairy-based additives. Food Chem 47: 257–261, 1993.
  • Shantha NC, Crum AD, Decker EA: Evaluation of conjugated linoleic acid concentrations in cooked beef. J Agric Food Chem 42: 1757–1760, 1994.
  • Chin SF, Liu W, Storkson JM, Ha YL, Pariza MW: Dietary sources of conjugated dienoic isomers of linoleic acid, a newly recognized class of anticarcinogens. J Food Comp Anal 5: 185–197, 1992.
  • Lin H, Boylston TD, Chang MJ, Luedecke LO, Shultz TD: Survey of the conjugated linoleic acid content of dairy products. J Dairy Sci 78: 2358–2365, 1995.
  • Kepler CR, Hirons KP, McNeill JJ, Tove SB: Intermediates and products of the biohydrogenation of linoleic acid by Butyrivibrio fibrisolvens. J Biol Chem 6: 1350–1354, 1966.
  • Chin SF, Storkson JM, Liu W, Albright KJ, Pariza MW: Conjugated linoleic acid (9,11- and 10,12-octadecadienoic acid) is produced in conventional but not germ-free rats fed linoleic acid. J Nutr 124: 694–701, 1994a.
  • Viviani R: Metabolism of long-chain fatty acids in the rumen. Adv Lipid Res 8: 267–346, 1970.
  • Dhiman TR, Anand GR, Satter LD, Pariza M: Dietary effects on conjugated linoleic acid content of cow’s milk. Abstract page 29, 87th AOCS Annual Meeting, Indianapolis, Indiana, April–May 1996
  • Stanton C, Lawless F, Kjellmer G, Harrington D, Devery R, Connolly JF, Murphy J: Dietary influences on Bovine milk cis-9, trans-11-conjugated linoleic acid content. J Food Sc 62: 1083–6, 1997.
  • Shantha NC, Decker EA, Ustunol Z: Conjugated linoleic acid concentrations in processed cheese. J Am Oil Chem Soc 69: 425–428, 1992.
  • Shantha NC: Conjugated linoleic acid concentrations in dairy products as affected by processing and storage. J Food Sci 60: 695, 1995.
  • Pariza MW, Ashoor SH, Chiu FS, Lund DB: Effects of temperature and time on mutagen formation in pan-fried hamburger. Cancer Lett 7: 63–9, 1979.
  • Cawood P, Wickens DG, Iverson SA, Braganza JM, Dormandy TL: The nature of diene conjugation in human serum, bile and duodenal juice. FEBS Lett 162: 239–243, 1983.
  • Harrison K, Cawood P, Iverson A, Dormandy TL: Diene conjugation patterns in normal serum. Life Chem Rep 3: 41–44, 1985.
  • Huang YC, Luedecke LO, Schultz TD: Effect of cheddar cheese consumption on plasma conjugated linoleic acid concentrations in men. Nutr Res 14: 373–386, 1994.
  • Ip C: The efficacy of conjugated linoleic-acid in mammary cancer prevention is independent of the level or type of fat in the diet. Carcinogenesis 17: 1045–1050, 1996.
  • Shultz TD, Chew BP, Seaman WR, Luedecke LO: Inhibitory effect of conjugated dienoic derivatives of linoleic acid and beta-carotene on the in vitro growth of human cancer cells. Cancer Lett 63: 125–133, 1992a.
  • Shultz TD, Chew BP, Seaman WR: Differential stimulatory and inhibitory responses of human MCF-7 breast cancer cells to linoleic acid and conjugated linoleic acid in culture. Anticancer Res 12(6B): 2143–2145, 1992b.
  • Schonberg A, Krokan HE: The inhibitory effect of conjugated diene derivatives (CLA) of linoleic acid on the growth of human tumor cell lines is in part due to increased lipid peroxidation. Anticancer Res 15: 1241–1246, 1995.
  • Pariza MW, Hargraves WA: A beef-derived mutagenesis modulator inhibits initiation of mouse epidermal tumors by 7,12-dimethylbenz[a]anthracene. Carcinogenesis 8: 1881–1887, 1985.
  • Ha YL, Grimm NK, Pariza MW: Anticarcinogens from fried ground beef: heat-altered derivatives of linoleic acid. Carcinogenesis 8: 1881–1887, 1987.
  • Ha YL, Storkson J, Pariza MW: Inhibition of benz(a)pyrene-induced mouse forestomach neoplasia by conjugated dienoic derivatives of linoleic acid. Cancer Res 50: 1097–1101, 1990.
  • Ip C, Chin SF, Scimeca JA, Pariza MW: Mammary cancer prevention by conjugated dienoic derivative of linoleic acid. Cancer Res 51: 6118–6124, 1991.
  • Ip C, Singh M, Thompson HJ, Scimeca JA: Conjugated linoleic acid suppresses mammary carcinogenesis and proliferative activity of the mammary gland in the rat. Cancer Res 54: 1212–1215, 1994a.
  • Zu HX, Schut HAJ: Inhibition of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-DNA adduct formation in CDF1 mice by heat-altered derivatives of linoleic acid. Food Chem Toxicol 30: 9–16, 1992.
  • Liew C, Schut HAJ, Pariza MW, Dashwood RH: Protection of conjugated linoleic acids against 2-amino-3methylimidazol[4,5-f]quinoline-induced colon carcinogenesis in the F344 rat: a study of inhibitory mechanisms. Carcinogenesis 16: 3037–3043, 1995.
  • Visonneau S, Cesano A, Tepper SA, Scimeca JA, Santoli D, Kritchevsky D: Conjugated linoleic acid suppresses the growth of human breast adenocarcinoma cells in SCID mice. Anticancer Res 17(2A): 969–973, 1997.
  • Lee NK, Kritchevsky D, Pariza MW: Conjugated linoleic acid and atherosclerosis in rabbits. Atherosclerosis 108: 19–25, 1994.
  • Nicolosi RJ, Laitinen L: Dietary conjugated linoleic acid reduces aortic fatty streak formation greater than linoleic acid in hypercholesterolemic hamsters. FASEB Journal abstr #2751, 1996.
  • Sugano M, Tsujita A, Yamasaki M, Ikeda I, Kritchevsky D: Lymphatic recovery, tissue distribution, and metabolic effects of conjugated linoleic acid in rats. J Nutr Biochem 8: 38–43, 1997.
  • Cook ME: Nutrition and the immune response of domestic fowl. Crit Rev Poultry Biol 3: 167–189, 1991.
  • Klasing KC, Laurin DE, Peng RK, Fry DM: Immunologically mediated growth depression in chicks: influence of feed intake, corticosterone, and interleukin-1. J Nutr 117: 1629–1637, 1987.
  • Cook ME, Miller CC, Park Y, Pariza MW: Immune modulation by altered nutrient metabolism: nutritional control of immune-induced growth depression. Poultry Sci 72: 1301–1305, 1993.
  • Miller CC, Park Y, Pariza MW, Cook ME: Feeding conjugated linoleic acid to animals partially overcomes catabolic responses due to endotoxin injection. Biochem & Biophy Res Commun 198: 1107–1112, 1994.
  • Wong MW, Chew BP, Wong TS, Hosick HL, Boylston TD, Shultz TD: Effects of dietary conjugated linoleic acid on lymphocyte function and growth of mammary tumors in mice. Anticancer Res. 17(2A): 987–993, 1997.
  • Chin SF, Storkson JM, Liu W, Albright KJ, Cook ME, Pariza MW: Conjugated linoleic acid is a growth factor for rats as shown by enhanced weight gain and improved feed efficiency. J Nutr 124: 2344–2349, 1994b.
  • Pariza M, Park Y, Cook M, Albright K, Liu W, et al. FASEB J 10: Abstract #3227, 1996.
  • Park Y, Albright KJ, Liu W, Storkson JM, Cook ME, Pariza MW: Effect of conjugated linoleic acid on body composition in mice. Lipids 32: 853–858, 1997.
  • Knekt P, Jarvinen R, Seppanen R, Pukkala E, Aromaa A: Intake of dairy products and risk of breast cancer. Br J Cancer 73: 687–691, 1996.

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