Constructive Interactions among Nutrients and Bone-Active Pharmacologic Agents with Principal Emphasis on Calcium, Phosphorus, Vitamin D and Protein

REFERENCES

• Eaton B, Nelson DA: Calcium in evolutionary perspective. Am J Clin Nutr 54: 281S–287S, 1991.
   PubMed Web of Science ®Google Scholar
• McKane WR, Khosla S, Egan KS, Robins SP, Burritt MF, Riggs BL: Role of calcium intake in modulating age-related increases in parathyroid function and bone resorption. J Clin Endocrinol Metab 81: 1699–1703, 1996.
   PubMed Web of Science ®Google Scholar
• Carroll MD, Abraham S, Dresser CM: Dietary intake source data: United States, 1976–80, Vital and health Statistics. Series 11-No. 231. DHHS Pub. No. (PHS) 83-1681. National Center for Health Statistics, Public Health Service. Washington. U.S. Government Printing Office, 1983.
   Google Scholar
• Parfitt AM: Osteomalacia and related disorders. In Avioli LV, Krane SM (eds): “Metabolic Bone Disease and Clinically Related Disorders,” 2nd ed. Philadelphia: WB Saunders, pp 329–396, 1990.
   Google Scholar
• Vieth R: Vitamin D supplementation, 25-hydroxyvitamin D levels, and safety. Am J Clin Nutr 69: 842–856, 1999.
   PubMed Web of Science ®Google Scholar
• Institute of Medicine: “Dietary Reference Intakes for Calcium, Magnesium, Phosphorus, Vitamin D, and Fluoride.” Food and Nutrition Board, Institute of Medicine. Washington, DC: National Academy Press, 1997.
   Google Scholar
• Delmi M, Rapin CH, Bengoa JM, Delmas PD, Vasey H, Bonjour JP: Dietary supplementation in elderly patients with fractured neck of the femur. Lancet 335: 1013–1016, 1990.
   PubMed Web of Science ®Google Scholar
• Schürch MA, Rizzoli R, Slosman D, Bonjour J-Ph: Protein supplements increase serum IGF-1 and decrease proximal femur bone loss in patients with a recent hip fracture. In Papapoulos SE, Lips P, Pols HAP, Johnston CC, Delmas PD (eds): “Osteoporosis 1996.” Amsterdam: Elsevier Science BV, pp. 327–329, 1996.
   Google Scholar
• Liberman UA, Weiss SR, Bröll J, Minne HW, Quan H, Bell NH, Rodriguez-Portales J, Downs RW Jr, Dequeker J, et al: Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis. N Engl J Med 333: 1437–1443, 1995.
   PubMed Web of Science ®Google Scholar
• Black DM, Cummings SR, Karpf DB, Cauley JA, Thompson DE, Nevitt MC, et al.: Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Lancet 348: 1535–1541, 1996.
   PubMed Web of Science ®Google Scholar
• Cummings SR, Black DM, Thompson DE, Applegate WB, Barrett-Connor E, Musliner TA, et al.: Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures. JAMA 280: 2077–2082, 1998.
   PubMed Web of Science ®Google Scholar
• Harris ST, Watts NB, Genant HK, McKeever CD, Hangartner T, Keller M, Chesnut CH III, Brown J, Eriksen EF, Hoseyni MS, Axelrod DW, Miller PD: Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. JAMA 282: 1344–1352, 1999.
   PubMed Web of Science ®Google Scholar
• Ettinger B, Black DM, Mitlak BH, Knickerbocker RK, Nickelsen T, Genant HK, Christiansen C, Delmas PD, Zanchetta JR, et al: Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene. JAMA 282: 637–645, 1999.
   PubMed Web of Science ®Google Scholar
• Heaney RP, Recker RR, Stegman MR, Moy AJ: Calcium absorption in women: relationships to calcium intake, estrogen status, and age. J Bone Miner Res 4: 469–475, 1989.
   PubMed Web of Science ®Google Scholar
• O’Brien KO, Abrams SA, Liang LK, Ellis KJ, Gagel RF: Increased efficiency of calcium absorption during short periods of inadequate calcium intake in girls. Am J Clin Nutr 63: 579–583, 1996.
   PubMed Web of Science ®Google Scholar
• Heaney RP, Recker RR: Determinants of endogenous fecal calcium in healthy women. J Bone Miner Res 9: 1621–1627, 1994.
   PubMed Web of Science ®Google Scholar
• Nieves JW, Komar L, Cosman F, Lindsay R: Calcium potentiates the effect of estrogen and calcitonin on bone mass: review and analysis. Am J Clin Nutr 67: 18–24, 1998.
   PubMed Web of Science ®Google Scholar
• Lindsay R, Hart DM, Clark DM: The minimum effective dose of estrogen for prevention of postmenopausal bone loss. Obstet Gynecol 63: 759–763, 1984.
   PubMed Web of Science ®Google Scholar
• Speroff L, Rowan J, Symons J, Genant H, Wilborn W: The comparative effect on bone density, endometrium, and lipids of continuous hormones as replacement therapy (CHART Study). JAMA 276: 1397–1403, 1996.
   PubMed Web of Science ®Google Scholar
• Harris ST, Genant HK, Baylink DJ, Gallagher JC, Karp SK, McConnell MA, et al: The effects of estrone (Ogen) on spinal bone density of postmenopausal women. Arch Intern Med 151: 1980–1984, 1991.
   PubMed Web of Science ®Google Scholar
• Genant HK, Lucas J, Weiss S, Akin M, Emkey R, McNaney-Flint H, Downs R, Mortola J, et al: Low-dose esterified estrogen therapy. Arch Intern Med 157: 2609–2615, 1997.
   PubMed Web of Science ®Google Scholar
• Recker RR, Davies KM, Dowd RM, Heaney RP: The effect of low-dose continuous estrogen and progesterone therapy with calcium and vitamin D in elderly women. Ann Int Med 130: 897–904, 1999.
   PubMed Web of Science ®Google Scholar
• Dure-Smith BA, Farley SM, Linkhart SG, Farley JR, Baylink DJ: Calcium deficiency in fluoride-treated osteoporotic patients despite calcium supplementation. J Clin Endocrinol Metab 81: 269–275, 1996.
   PubMed Web of Science ®Google Scholar
• Neer RM, Arnaud CD, Zanchetta JR, Prince R, Gaich GA, Reginster JY, Hodsman AB, Eriksen EF, Ish-Shalom S, Genant HK, Wang O, Mitlak BH: Effect of parathyroid hormone (1–34) on fractures and bone mineral density in postmenopausal women with osteoporosis. N Engl J Med 344: 1434–1441, 2001.
   PubMed Web of Science ®Google Scholar
• Slovik DM, Rosenthal DI, Doppelt SH, Potts JT Jr, Daly MA, Campbell JA, Neer RM: Restoration of spinal bone in osteoporotic men by treatment with human parathyroid hormone (1-34) and 1,25-dihydroxyvitamin D. J Bone Miner Res 1: 377–381, 1986.
   PubMed Web of Science ®Google Scholar
• Dawson-Hughes B, Harris SS, Krall EA, Dallal GE: Effect of calcium and vitamin D supplementation on bone density in men and women 65 years of age or older. N Engl J Med 337: 670–676, 1997.
   PubMed Web of Science ®Google Scholar
• Chapuy MC, Arlot ME, Duboeuf F, Brun J, Crouzet B, Arnaud S, Delmas PD, Meunier PJ: Vitamin D3 and calcium to prevent hip fractures in elderly women. N Engl J Med 327: 1637–1642, 1992.
   PubMed Web of Science ®Google Scholar
• Peacock M, Liu G, Carey M, McClintock R, Ambrosius W, Hui S, Johnston CC Jr: Effect of calcium or 25OH vitamin D3 dietary supplementation on bone loss at the hip in men and women over the age of 60. J Clin Endocrinol Metab 85: 3011–3019, 2000.
   PubMed Web of Science ®Google Scholar
• Cordain L, Brand-Miller J, Eaton SB, Mann N, Holt SHA, Speth JD: Plant-animal subsistence ratios and macronutrient energy estimations in worldwide hunter-gatherer diets. Am J Clin Nutr 71: 682–692, 2000.
   PubMed Web of Science ®Google Scholar
• Richards MP, Pettitt PB, Trinkaus E, Smith FH, Paunović M, Karavanić I: Neanderthal diet at Vindija and Neanderthal predation: the evidence from stable isotopes. Proc Natl Acad Sci 97: 7663–7666, 2000.
   PubMed Web of Science ®Google Scholar
• González-Reimers E, Arnay-de-la-Rosa M: Ancient skeletal remains of the Canary Islands: bone histology and chemical analysis. Anthrop Anz 50: 201–215, 1992.
   PubMedGoogle Scholar
• Hannan MT, Tucker KL, Dawson-Hughes B, Cupples LA, Felson DT, Kiel DP: Effect of dietary protein on bone loss in elderly men and women. The Framingham Study. J Bone Miner Res 15: 2504–2512, 2000.
   PubMed Web of Science ®Google Scholar
• Heaney RP, Recker RR: Effects of nitrogen, phosphorus, and caffeine on calcium balance in women. J Lab Clin Med 99: 46–55, 1982.
   PubMed Web of Science ®Google Scholar
• Bastow MD, Rawlings J, Allison SP: Benefits of supplementary tube feeding after fractured neck of femur. Br Med J 287: 1589–1592, 1983.
   PubMed Web of Science ®Google Scholar
• Schürch M-A, Rizzoli R, Slosman D, Vadas L, Vergnaud P, Bonjour J-P: Protein supplements increase serum insulin-like growth factor-I levels and attenuate proximal femur bone loss in patients with recent hip fracture. Ann Intern Med 128: 801–809, 1998.
   PubMed Web of Science ®Google Scholar
• Heaney RP: Protein intake and bone health: the influence of belief systems on the conduct of nutritional science. Am J Clin Nutr 73: 5–6, 2001.
   PubMed Web of Science ®Google Scholar
• Krook L, Whalen JP, Lesser GV, Berens DL: Experimental studies on osteoporosis. Methods Achiev Exp Pathol 7: 72–108, 1975.
   PubMedGoogle Scholar
• Jowsey J: Osteoporosis: Dealing with a crippling bone disease of the elderly. Geriatrics 32(7): 41–50, 1977.
   Google Scholar
• Chinn HI: Effects of dietary factors on skeletal integrity in adults: Calcium, phosphorus, vitamin D, and protein. Prepared for Bureau of Foods, Food and Drug Administration, U.S. Department of Health and Human Services, Washington, D.C., 1981.
   Google Scholar