References
- World Health Organization. Non-communicable diseases country profiles 2020. Geneva: World Health Organization; 2020.
- Rivera-Dommarco J, Villalpando S. Encuesta Nacional de Nutrición (ENN): Estado de Nutrición en Niños y Mujeres en México. Cuernavaca, Morelos, México: Instituto Nacional de Salud Pública, 1988; 320.
- World Health Organization. Noncommunicable disease country profiles 2018. Geneva: World Health Organization; 2018.
- Clark SE, Hawkes C, Murphy SME Hansen-Kuhn KA,Wallinga D. Exporting obesity: US farm and trade policy and the transformation of the Mexican consumer food environment. Int J Occup Environ Health. 2012;18(1):53–65. doi:https://doi.org/10.1179/1077352512Z.0000000007.
- Instituo Nacional de Salud Pública. Encuesta Nacional de Salud y Nutrición. Ensanut. 2018;1:47. doi:https://doi.org/10.1017/CBO9781107415324.004.
- Organización para la Cooperación y el Desarrollo Económicos. Obesity update 2017. Diabetologe. 2017;13:331–41. doi:https://doi.org/10.1007/s11428-017-0241-7.
- Dommarco J, Colchero A, Gonzales T, Hernandez G. La obesidad en México.Estado de la política pública y recomendaciones para su prevención y control. Cuernavaca (MEX): Instituto de salud pública; 2018.
- Ehman EC, Johnson GB, Villanueva-Meyer JE, Cha S, Leynes AP, Eric P, Larson Z, Hope TA. PET/MRI: Where might it replace PET/CT? J Magn Reson Imaging. 2017; 46:1247–62. doi:https://doi.org/10.1002/jmri.25711.
- De Los M, Espinosa-Cuevas Á. Enfermedad renal. Gac Med Mex. 2016;152:90–6.
- Soto-Estrada G, Moreno-Altamirano L, Pahua Díaz D. Panorama epidemiológico de México, principales causas de morbilidad y mortalidad. Rev La Fac Med. 2016;59:8–22.
- IMSS. Modelo Preventivo de Enfermedades Crónicas. https://www.gob.mx/cms/uploads/attachment/file/220584/prev_ecnt_imss_01.pdf; 2017, 28. http://www.beta.inegi.org.mx/proyectos/ccpv/1970/.
- IMSS. Guía de Referencia Rápida Prevención, Diagnóstico y Tratamiento de la Enfermedad Renal Crónica Temprana Guía de Práctica Clínica GPC Catálogo maestro de guías de práctica clínica: IMSS-335-09. Guia Práctica Clínica. (n.d.). http://www.imss.gob.mx/sites/all/statics/guiasclinicas/335GRR.pdf.
- Mercado-Martínez FJ, Hernández-Ibarra E, Ascencio-Mera CD, Díaz-Medina BA, Padilla-Altamira C, Kierans C. Viviendo con trasplante renal, sin protección social en salud: ¿Qué dicen los enfermos sobre las dificultades económicas que enfrentan y sus efectos? TT - Kidney transplant patients without social protection in health: what do patients say about the econ. Cad Saúde Públ. 2014;30(10):2092–100. doi:https://doi.org/10.1590/0102-311X00150713.
- Ávila-Saldivar MN, Conchillos-Olivares G, Rojas-Báez IC, Ordoñez-Cruz AE, Ramírez-Flores HJ. Enfermedad renal crónica: causa y prevalencia en la población del Hospital general la Perla. Med. Interna Mex. 2013;29:473–8.
- Quintero FS, Botero V, D'Agostino D, Carbajal LD, Olivera MRD, Guzmán C, Játiva E, Martin GT, Castro MM, Paranza LO, et al. Enfermedad de hígado graso no alcohólico (EHGNA): revisión y puesta al día. Grupo de trabajo de la Sociedad Latinoamericana de Gastroenterología Hepatología y Nutrición Pediárica (SLAGHNP). Acta Gastroenterol. Latinoam. 2016;46:246–64.
- Liu Y, Zhong GC, Tan HY, Hao FB, Hu JJ. Nonalcoholic fatty liver disease and mortality from all causes, cardiovascular disease, and cancer: a meta-analysis. Sci Rep. 2019;9(1):11124 doi:https://doi.org/10.1038/s41598-019-47687-3.
- Guyton A, Hall J. Los líquidos corporales y los riñones. Guyt Hall Tratado Fisiol Méd. 2010;12:1092. doi:https://doi.org/10.1093/jhered/est132.
- Carrero JJ, Stenvinkel P, Cuppari L, Ikizler TA, Kalantar-Zadeh K, Kaysen G, Mitch WE, Price SR, Wanner C, Wang AYM, et al. Etiology of the protein-energy wasting syndrome in chronic kidney disease: a consensus statement from the International Society of Renal Nutrition and Metabolism (ISRNM). J Ren Nutr. 2013;23(2):77–90. doi:https://doi.org/10.1053/j.jrn.2013.01.001.
- NIDDK. Los riñones y cómo funcionan. Natl Kidney Urol Dis Inf Clear. 2009;8:16.
- González-Casaus ML. Vitamina. D en la enfermedad renal crónica. Nefrología al día 2012;7:0.
- Alcázar Arroyo R. Alteraciones electrolíticas y del equilibrio ácido-base en la enfermedad renal crónica avanzada. Nefrología. 2008;23:87–93.
- Méndez-Durán A, Francisco Méndez-Bueno J, Tapia-Yáñez T, Montes AM, Aguilar-Sánchez L. Epidemiología de la insuficiencia renal crónica en México. Dial Traspl. 2010;31(1):7–11. doi:https://doi.org/10.1016/S1886-2845(10)70004-7.
- Cabrera L, Ruiz B, Sancho A. Eritropoyetina: revisión de sus indicaciones. Inf Ter Sist Nac Salud. 2009;33:3–9.
- Bover J, Egido J, Fernández-Giráldez E, Praga M, Solozábal-Campos C, Torregrosa JV, Martínez-Castelao A. Vitamin D, vitamin D receptor and the importance of its activation in patients with chronic kidney disease. Nefrologia. 2015;35(1):28–41. doi:https://doi.org/10.3265/Nefrologia.pre2014.Sep.11796.
- Alarcón-Sotelo A, Espinosa-Sevilla A, Díaz-Greene E, Rodríguez-Weber FL. Glucosa y riñón: Ruptura del paradigma. Med Interna Mex. 2015;31:296–300.
- Calvo-Vázquez I, Sánchez-Luna O, Yáñez-Sosa AL. Prevalencia de enfermedad renal crónica no diagnosticada en pacientes con diabetes mellitus tipo 2 en atención primaria a la salud. Med. Interna Mex. 2015;31:41–9.
- Fernández C, Navarro M. Protocolo de Diagnóstico Terapéuticos de la AEP:Tratamiento de la insuficiencia renal crónica. 1 ed. Madrid (ES): Asociación Española de Pediatría; 2008. p. 240–50.
- Fierro, JA. Nefropatía diabética: fisiopatología, diagnóstico, evolución clínica y epidemiología. Rev Med Clin Condes. 2009;20:639–50.
- Ros Pérez M, Medina-Gómez G. [Obesity, adipogenesis and insulin resistance]. Endocrinol Nutr. 2011;58(7):360–9. doi:https://doi.org/10.1016/j.endonu.2011.05.008.
- Teta D. Insulin resistance as a therapeutic target for chronic kidney disease. J Ren Nutr. 2015;25(2):226–9. doi:https://doi.org/10.1053/j.jrn.2014.10.019.
- Kidney Disease: Improving Global Outcomes (KDIGO) Anemia Work Group. KDIGO Clinical Practice Guideline for Anemia in Chronic Kidney Disease. Kidney Int Suppl. 2012;2:279–335. doi:https://doi.org/10.1038/kisup.2012.40.
- Espinosa-Sevilla A, Amezcua-Macías AI, Ruiz-Palacios PC, Rodríguez-Weber F, Díaz-Greene E. Nuevos marcadores de lesión renal aguda en el enfermo grave. Med. Interna Mex. 2013;29:513–7.
- Puyol Rodríguez M, Marqués ML, López JJV, Puyol DR. Biomarcadores en el diagnóstico de las patologías renales. Monogr La Real Acad Nac Farm. 2010;0:369–414.
- Panizo N, Goicoechea M, de Vinuesa SG, Arroyo D, Yuste C, Rincón A, Verdalles U, Ruiz-Caro C, Quiroga B, Luño J. Progresión de la enfermedad renal crónica en pacientes con enfermedad poliquística autosómica dominante. Nefrologia. 2012;32:197–205. doi:https://doi.org/10.3265/Nefrologia.pre2011.Nov.10962.
- Aguilar A, Barrera M, Gómez A, González C, Méndez G. Tratamiento sustitutivo de la funcion renal. Diálisis y Hemodiálisis en la insuficiencia renal crónica. Secr Salud. 2014;1:7–9.
- Sönmez MF, Narin F, Akkuş D, Türkmen AB. Melatonin and vitamin C ameliorate alcohol-induced oxidative stress and eNOS expression in rat kidney. Ren Fail. 2012;34(4):480–6. doi:https://doi.org/10.3109/0886022X.2011.649678.
- Mónica Cuevas P, Pía Rosati M, Francisco Cano S. Tratamiento de la anemia con eritropoietina y hierro en enfermedad renal crónica. Rev Chil Pediatr. 2008;79:131–45. doi:https://doi.org/10.4067/s0370-41062008000200002.
- María D, Sansone S. Actualización en medicamentos antidiabéticos y riesgo cardiovascular. Rev Uruguaya Cardiol. 2016;31:522–46.
- Delgado Coello BA. Avances en el estudio experimental de la Bioquímica Hepática. Av. En El Estud. Exp. La Bioquímica Hepática. 1(2017);1–189. doi:https://doi.org/10.22201/ifc.9786070290763e.2017.
- Caro-Sabido EA, Larrosa-Haro A. Efficacy of dietary intervention and physical activity in children and adolescents with nonalcoholic fatty liver disease associated with obesity: a scoping review. Rev Gastroenterol México (Engl Ed). 2019;84(2):185–94. doi:https://doi.org/10.1016/j.rgmxen.2019.02.010.
- Leoni S, Tovoli F, Napoli L, Serio I, Ferri S, Bolondi L. Current guidelines for the management of non-alcoholic fatty liver disease: a systematic review with comparative analysis. World J Gastroenterol. 2018;24(30):3361–73. doi:https://doi.org/10.3748/wjg.v24.i30.3361.
- Chiang J. Liver Physiology: Metabolism and Detoxification. Pathobiology of Human Disease. 2014;1:1770–1776
- Zhuang Y, Xing C, Cao H, Zhang C, Luo J, Guo X, Hu G. Insulin resistance and metabonomics analysis of fatty liver haemorrhagic syndrome in laying hens induced by a high-energy low-protein diet. Sci. Rep. 2019;9:1–14. doi:https://doi.org/10.1038/s41598-019-46183-y.
- Idrovo V, Guevara G. Enfermedad hepatica grasa no alcoholica: NALFD. Rev Colomb Gastroenterol. 2004;19:44–9.
- Mew NA, Pappa MB, Gropman AL. Urea cycle disorders. 5th ed. Elsevier Inc., Washington, DC, USA, 2014;633–647.
- Barmore W, Azad F, Stone WL. Physiology, Urea Cycle. [Updated 2020 Jul 27]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 jan-.
- Aguilar JC. Función inmunológica del hígado desde la perspectiva de la vacunación terapéutica. Biotecnol Apl. 2010;27:1–17.
- Romero-Martínez M, Shamah-Levy T, Cuevas-Nasu L, Gómez-Humarán IM, Gaona-Pineda EB, Gómez-Acosta LM, Rivera-Dommarco JÁ, Hernández-Ávila M. [Methodological design of the National Health and Nutrition Survey 2016]. Salud Publ Mex. 2017;59(3):299–305. doi:https://doi.org/10.21149/8593.
- Delgado-Cortés HM, García-Juárez FI, García-Juárez I. La enfermedad por hígado graso no alcohólico y el trabajo del internista. Rev Hosp Jua Mex. 2018;85(2):86–93.
- Bernal-Reyes R. Hígado graso, esteatohepatitis no alcohólica y alcohólica, Rev Gastroenterol México. 2015;80:41–3.
- Diehl AM, Day C. Cause, pathogenesis, and treatment of nonalcoholic steatohepatitis. N Engl J Med. 2017;377(21):2063–72. doi:https://doi.org/10.1056/NEJMra1503519.
- Brunt EM, Tiniakos DG. Histopathology of nonalcoholic fatty liver disease. World J Gastroenterol. 2010;16(42):5286–96. doi:https://doi.org/10.3748/wjg.v16.i42.5286.
- Brunt E M, Janney C G, Bisceglie A M, Neuschwander-Tetri B A, Bacon B R. Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. Am J Gastroenterology. 1999;94(9):2467–74. doi:https://doi.org/10.1111/j.1572-0241.1999.01377.x.
- Ospina JR, Restrepo JC. Síndrome hepatorrenal: fisiopatología, diagnóstico y manejo. Rev Colomb Gastroenterol. 2017;31(2):146–53. doi:https://doi.org/10.22516/25007440.83.
- Sepúlveda Palamara RA, Jalil Milad R, Arteaga Llona AA, Maiz G A, Rigotti R A. Estatinas en enfermedad renal crónica. ARS Med. 2017;42(1):68–75. doi:https://doi.org/10.11565/arsmed.v42i1.654.
- Jha V. Herbal medicines and chronic kidney disease. Nephrology. 2010;15:10–7. doi:https://doi.org/10.1111/j.1440-1797.2010.01305.x.
- Cooke J. Practical aspects of herbal supplement use in chronic kidney disease. J Ren Nutr. 2004;14(1):e1–4. doi:https://doi.org/10.1053/j.jrn.2003.09.012.
- Luyckx VA. Nephrotoxicity of alternative medicine practice. Adv Chronic Kidney Dis. 2012;19(3):129–41. doi:https://doi.org/10.1053/j.ackd.2012.04.005.
- Andrade-Cetto A, Heinrich M. Mexican plants with hypoglycaemic effect used in the treatment of diabetes. J Ethnopharmacol. 2005;99(3):325–48. doi:https://doi.org/10.1016/j.jep.2005.04.019.
- Chua LS. A review on plant-based rutin extraction methods and its pharmacological activities. J Ethnopharmacol. 2013;150(3):805–17. doi:https://doi.org/10.1016/j.jep.2013.10.036.
- Ross-Ibarra J. Origen y domesticación de la chaya (Cnidoscolus aconitifolius Mill I. M. Johnst): La espinaca Maya. Mex Stud Mex. 2003;19(2):287–302. doi:https://doi.org/10.1525/msem.2003.19.2.287.
- Ross-Ibarra J, Molina-Cruz A. The ethnobotany of Chaya (Cnidoscolus aconitifolius ssp. aconitifolius Breckon): a nutritious Maya vegetable. Econ Bot. 2002;56(4):350–65. doi:https://doi.org/10.1663/0013-0001(2002)056[0350:teocca]2.0.co;2.
- Cifuentes R, Pöll E, Bressani R, Yurrita S. Caracterización Botánica, Molecular, Agronómica y Química de los cultivares de chaya (Cnidoscolus aconitifolius) de Guatemala. Revista 21 de la Universidad del Valle de Guatemala. (2010) 21:34–49.
- Markus V, Paul A, Yahaya J, Zakka J, Yatai K, Oladeji M. An underexploited tropical plant with promising economic value and the window of opportunities for researchers: Cnidoscolus aconitifolius. Am J Food Sci Nutr Res. 2016;3:177–87.
- Pérez-González MZ, Gutiérrez-Rebolledo GA, Yépez-Mulia L, Rojas-Tomé IS, Luna-Herrera J, Jiménez-Arellanes MA. Antiprotozoal, antimycobacterial, and anti-inflammatory evaluation of Cnidoscolus chayamansa (Mc Vaugh) extract and the isolated compounds. Biomed Pharmacother. 2017;89:89–97. doi:https://doi.org/10.1016/j.biopha.2017.02.021.
- Akachukwu D, Okafor P, Ibegbulem C. Phytochemical content of Cnidoscolus aconitifolius leaves and toxicological effect of its aqueous leaf extract in Wistar rats. J Invest Biochem. 2014;3(1):26. doi:https://doi.org/10.5455/jib.20140504023102.
- Aye P. Effect of processing on the nutritive characteristics, anti-nutritional factors and functional properties of Cnidoscolus aconitifolius leaves (Iyana Ipaja) Animal Production and Health Sciences Department. Am J Food Nutr. 2012;2:89–95. doi:https://doi.org/10.5251/ajfn.2012.2.4.89.95.
- Johnston MIM, Nkeiruka U, Nsofor A, Anayo L, Ekwutosi T, Ugochi J. An evaluation of the phytochemical and nutritional compositions of fresh leaves of Cnidoscolus aconitifolius [Miller] I.M. Johnston. Int J Res Stud Biosci. 2016;4:21–8. doi:https://doi.org/10.20431/2349-0365.0406004.
- Chikezie, Nkeiruka, U., Chijioke, Nsofor, A., Adjeroh, Anayo, L., Ogbulie, Ekwutosi, T., Udensi, Ugochi, J., Oyirioha, & Chialuka, K.. An Evaluation of the Phytochemical and NutritionalCompositions of Fresh Leaves of Cnidoscolus Aconitifolius[Miller] I.M. 2016;4:21.
- Chukwunonye UCE, Gaza ASP, Obisike CV, Ejiofor NA, Obioma DE. Pharmacognostic studies of the leaf of Cnidoscolus aconitifolius. Indo Am J Pharm Sci 2017;4(2):496–506.
- Otitoju GTO, Otitoju O, Nwamarah JU, Ene-Obong HN. Anti-nutrient and phytochemical compositions of Psychotriasp, Cnidoscolusaconitifolius and Telfariaoccidentalis from South Eastern Nigeria. IOSR J Environ Sci Ver II. 2016;10:2319–99. doi:https://doi.org/10.9790/2402-10228690.
- Awoyinka OA, Balogun IO, Ogunnowo AA. Phytochemical screening and in vitro bioactivity of Cnidoscolus aconitifolius (Euphorbiacea). J. Med. Plants. Res. Barakate. 2007;1:63–5.
- Hamid AA, Oguntoye SO, Negi AS, Ajao A, Owolabi NO. Chemical constituents. Antibacterial, Antifungal and Antioxidant Activities of the Aerial Parts of Cnidoscolus Aconitifolius. Ife Journal of Science. 2016;18:561
- Kuti JO, Konoru HB. Cyanogenic glycosides content in two edible leaves of tree spinach (Cnidoscolus spp.). J Food Compos Anal. 2006;19(6–7):556–61. doi:https://doi.org/10.1016/j.jfca.2006.01.006.
- Borel P, Desmarchelier C. Bioavailability of fat-soluble vitamins and phytochemicals in humans: effects of genetic variation. Annu Rev Nutr. 2018;38:69–96. doi:https://doi.org/10.1146/annurev-nutr-082117-051628.
- Rein MJ, Renouf M, Cruz-Hernandez C, Actis-Goretta L, Thakkar SK, da Silva Pinto M. Bioavailability of bioactive food compounds: a challenging journey to bioefficacy. Br J Clin Pharmacol. 2013;75(3):588–602. doi:https://doi.org/10.1111/j.1365-2125.2012.04425.x.
- Kara M, Jakubczyk A, Szymanowska U, Złotek U, Zieli E. Review digestion and bioavailability of bioactive phytochemicals. Int J Food Sci Technol. 2017;52(2):291–305. doi:https://doi.org/10.1111/ijfs.13323.
- Kuti JO, Konuru HB. Antioxidant capacity and phenolic content in leaf extracts of tree spinach (Cnidoscolus spp.). J Agric Food Chem. 2004;52(1):117–21. doi:https://doi.org/10.1021/jf030246y.
- Ogunlade I, Tucker G, Fisk I, Ogunlade A. Evaluation of antioxidant activity and vitamin E profile of some selected indigenous vegetables in Nigerian diet. J Food Agric Environ. 2009;7:143–5.
- Onuoha NO, Okafor AM, Eme PE, Odo EC. Haematinic effect of raw and boiled leaf juice of cnidoscolus aconitifolius using cyclophosphamide-treated adult male albino rats. EC Nutr 2017;5:187–94.
- Emelike CU, Unegbu GO. Effects of oral administration of Cnidoscolus aconitifolius leaf extract (chaya tea) on biomarkers of cardiovascular system of Wistar albino rats. Adv Biol Res. 2015;9:182–8. doi:https://doi.org/10.5829/idosi.abr.2015.9.3.93209.
- García-Rodríguez RV, Gutiérrez-Rebolledo GA, Méndez-Bolaina E, Sánchez-Medina A, Maldonado-Saavedra O, Domínguez-Ortiz MÁ, Vázquez-Hernández M, Muñoz-Muñiz OD, Cruz-Sánchez JS. Cnidoscolus chayamansa Mc Vaugh, an important antioxidant, anti-inflammatory and cardioprotective plant used in Mexico. J Ethnopharmacol. 2014;151(2):937–43. doi:https://doi.org/10.1016/j.jep.2013.12.004.
- Aderian OI, Olajide OO, Igwemmar NC, Orishadipe AT. Phytochemical constituents, antimicrobial and antioxidant potentials of tree spinach [Cnidoscolus aconitifolius (Miller) I. M. Johnston]. J Med Plants Res. 2013;7:1317–22. doi:https://doi.org/10.5897/JMPR12.899.
- Olaniyan M, Ozuaruoke D, Afolabi T. Cholesterol lowering effect of Cnidoscolous aconitifolius leave extracts in egg yolk induced hypercholesterolemia in rabbit. J Adv Med Med Res. 2017;23(1):1–6. doi:https://doi.org/10.9734/JAMMR/2017/35431.
- Roy D, Ferdiousi N, Khatun T, Moral M. Phytochemical screening, nutritional profile and anti-diabetic effect of ethanolic leaf extract of Cnidoscolus aconitifolius in streptozotocin induce diabetic mice. Int J Basic Clin Pharmacol. 2016;5:2244–50. doi:https://doi.org/10.18203/2319-2003.ijbcp20163269.
- Oyagbemi AA, Odetola AA. Hepatoprotective effects of ethanolic extract of Cnidoscolus aconitifolius on paracetamol-induced hepatic damage in rats. Pak J Biol Sci. 2010;13(4):164–9. doi:https://doi.org/10.3923/pjbs.2010.164.169.
- Oyagbemi A, Odetola A. Hepatoprotective and nephroprotective effects of Cnidoscolus aconitifolius in protein energy malnutrition induced liver and kidney damage. Phcog Res. 2013;5(4):260. doi:https://doi.org/10.4103/0974-8490.118817.
- Orji O, Okechukwu PCU, Ezeani N, Nzubechukwu E. Biochemical assessment of ethanol leaf extract of Cnidoscolus aconitifolius on liver integrity of albino rat treated with lead. Glob J Pharmacol. 2016;10:108–13. doi:https://doi.org/10.5829/idosi.gjp.2016.108.113.
- Saba AB, Oyagbemi AA, Azeez OI. Amelioration of carbon tetrachloride-induced hepatotoxicity and haemotoxicity by aqueous leaf extract of Cnidoscolus aconitifolius in rats. Niger J Physiol Sci. 2010;25(2):139–47.
- Adekomi D, Tijani A, Adeniy T, Olajide J. Some of the effects of aqueous leaf extract of Cnidoscolous aconitifolius (Euphorbiaceae) on the morphology and histology of the kidney and liver of Sprague Dawley rat. Trop J Health Sci. 2011;18:9–15. doi:https://doi.org/10.4314/tjhc.v18i1.64478.
- Ramos-Gomez M, Mendoza S, Loarca-Piña G, Figueroa-Pérez MG, Reynoso-Camacho R, Quezada-Tristán T, Guzman-Maldonado H. Phytochemical profile, antioxidant properties and hypoglycemic effect of Chaya (Cnidoscolus chayamansa) in STZ-induced diabetic rats. J Food Biochem. 2017;41(1):e12281. doi:https://doi.org/10.1111/jfbc.12281.
- Kuri-García A, Chávez-Servín JL, Guzmán-Maldonado SH. Phenolic profile and antioxidant capacity of Cnidoscolus chayamansa and Cnidoscolus aconitifolius: a review. J Med Plants Res. 2017;11(45):713–27. doi:https://doi.org/10.5897/JMPR2017.6512.
- Adaramoye OA, Aluko A. Methanolic extract of Cnidoscolus aconitifolius attenuates renal dysfunction induced by chronic ethanol administration in Wistar rats. Alcohol Alcohol. 2011;46(1):4–9. doi:https://doi.org/10.1093/alcalc/agq082.
- Kalantar-Zadeh K, Fouque D. Nutritional management of chronic kidney disease. N Engl J Med. 2017;377(18):1765–76. doi:https://doi.org/10.1056/NEJMra1700312.
- Ajiboye BO, Ojo OA, Okesola MA, Oyinloye BE, Kappo AP. Ethyl acetate leaf fraction of Cnidoscolus aconitifolius (Mill.) I. M. Johnst: antioxidant potential, inhibitory activities of key enzymes on carbohydrate metabolism, cholinergic, monoaminergic, purinergic, and chemical fingerprinting. Int J Food Prop. 2018;21(1):1697–715. doi:https://doi.org/10.1080/10942912.2018.1504787.
- Iyke W, Arthur N, Bestman N, Uchenna N, Numbara D. Investigation of Phytocomponents and Hypoglycaemic Effect of Hydro-methanolic Leaf Extract of Cnidoscolus aconitifolius(Spinach Tree) in Streptozotocin Induced- Diabetic Wistar Rats. JOCAMR. 2018;5(3):1–9. doi:https://doi.org/10.9734/JOCAMR/2018/26858.