Active Consumption of Konjac and Konjac Products Improves Blood Glucose Control in Patients with Type 2 Diabetes Mellitus

References

• Chua M, Baldwin TC, Hocking TJ, Chan K. Traditional uses and potential health benefits of Amorphophallus konjac K. Koch ex N.E.Br. J Ethnopharmacol. 2010;128(2):268–78. doi:10.1016/j.jep.2010.01.021.
   PubMed Web of Science ®Google Scholar
• Englyst HN, Cummings JH. Digestion of the polysaccharides of some cereal foods in the human small intestine. Am J Clin Nutr. 1985;42(5):778–87. doi:10.1093/ajcn/42.5.778.
   PubMed Web of Science ®Google Scholar
• Bessell E, Maunder A, Lauche R, Adams J, Sainsbury A, Fuller NR. Efficacy of dietary supplements containing isolated organic compounds for weight loss: a systematic review and meta-analysis of randomised placebo-controlled trials. Int J Obes. 2021;45(8):1631–43. doi:10.1038/s41366-021-00839-w.
   Web of Science ®Google Scholar
• Chen HL, Sheu WH, Tai TS, Liaw YP, Chen YC. Konjac supplement alleviated hypercholesterolemia and hyperglycemia in type 2 diabetic subjects–a randomized double-blind trial. J Am Coll Nutr. 2003;22(1):36–42. doi:10.1080/07315724.2003.10719273.
   PubMed Web of Science ®Google Scholar
• Devaraj RD, Reddy CK, Xu B. Health-promoting effects of konjac glucomannan and its practical applications: a critical review. Int J Biol Macromol. 2019;126:273–81. doi:10.1016/j.ijbiomac.2018.12.203.
   PubMed Web of Science ®Google Scholar
• Tester RF, Al-Ghazzewi FH. Beneficial health characteristics of native and hydrolysed konjac (Amorphophallus konjac) glucomannan. J Sci Food Agric. 2016;96(10):3283–91. doi:10.1002/jsfa.7571.
   PubMed Web of Science ®Google Scholar
• Kaats GR, Bagchi D, Preuss HG. Konjac glucomannan dietary supplementation causes significant fat loss in compliant overweight adults. J Am Coll Nutr. 2015:1–7. doi:10.1080/07315724.2015.1009194.
   Google Scholar
• Arvill A, Bodin L. Effect of short-term ingestion of konjac glucomannan on serum cholesterol in healthy men. Am J Clin Nutr. 1995;61(3):585–9. doi:10.1093/ajcn/61.3.585.
   PubMed Web of Science ®Google Scholar
• Chen HL, Cheng HC, Wu WT, Liu YJ, Liu SY. Supplementation of konjac glucomannan into a low-fiber Chinese diet promoted bowel movement and improved colonic ecology in constipated adults: a placebo-controlled, diet-controlled trial. J Am Coll Nutr. 2008;27(1):102–8. doi:10.1080/07315724.2008.10719681.
   PubMed Web of Science ®Google Scholar
• Doi K. Effect of konjac fibre (glucomannan) on glucose and lipids. Eur J Clin Nutr. 1995;49(Suppl 3):S190–S7.
   PubMedGoogle Scholar
• Ho HVT, Jovanovski E, Zurbau A, Blanco Mejia S, Sievenpiper JL, Au-Yeung F, Jenkins AL, Duvnjak L, Leiter L, Vuksan V. A systematic review and meta-analysis of randomized controlled trials of the effect of konjac glucomannan, a viscous soluble fiber, on LDL cholesterol and the new lipid targets non-HDL cholesterol and apolipoprotein B. Am J Clin Nutr. 2017;105(5):1239–47. doi:10.3945/ajcn.116.142158.
   PubMed Web of Science ®Google Scholar
• Vuksan V, Sievenpiper JL, Xu Z, Wong EY, Jenkins AL, Beljan-Zdravkovic U, Leiter LA, Josse RG, Stavro MP. Konjac-Mannan and American ginsing: emerging alternative therapies for type 2 diabetes mellitus. J Am Coll Nutr. 2001;20(5 Suppl):370S–80S. discussion 381S-383S. doi:10.1080/07315724.2001.10719170.
   PubMed Web of Science ®Google Scholar
• Sorapukdee S, Jansa S, Tangwatcharin P. Partial replacement of pork backfat with konjac gel in Northeastern Thai fermented sausage (Sai Krok E-san). Asian-Australas J Anim Sci. 2019;32(11):1763–75. doi:10.5713/ajas.18.0811.
   Web of Science ®Google Scholar
• Dai S, Corke H, Shah NP. Utilization of konjac glucomannan as a fat replacer in low-fat and skimmed yogurt. J Dairy Sci. 2016;99(9):7063–74. doi:10.3168/jds.2016-11131.
   PubMed Web of Science ®Google Scholar
• Dai S, Jiang F, Corke H, Shah NP. Physicochemical and textural properties of mozzarella cheese made with konjac glucomannan as a fat replacer. Food Res Int. 2018;107:691–9. doi:10.1016/j.foodres.2018.02.069.
   PubMed Web of Science ®Google Scholar
• Onakpoya I, Posadzki P, Ernst E. The efficacy of glucomannan supplementation in overweight and obesity: a systematic review and meta-analysis of randomized clinical trials. J Am Coll Nutr. 2014;33(1):70–8. doi:10.1080/07315724.2014.870013.
   PubMed Web of Science ®Google Scholar
• Vuksan V, Sievenpiper JL, Owen R, Swilley JA, Spadafora P, Jenkins DJ, Vidgen E, Brighenti F, Josse RG, Leiter LA, et al. Beneficial effects of viscous dietary fiber from Konjac-mannan in subjects with the insulin resistance syndrome: results of a controlled metabolic trial. Diabetes Care. 2000;23(1):9–14. doi:10.2337/diacare.23.1.9.
   PubMed Web of Science ®Google Scholar
• Keithley JK, Swanson B, Mikolaitis SL, DeMeo M, Zeller JM, Fogg L, Adamji J. Safety and efficacy of glucomannan for weight loss in overweight and moderately obese adults. J Obes. 2013;2013:610908. doi:10.1155/2013/610908.
   PubMedGoogle Scholar
• Au-Yeung F, Jovanovski E, Jenkins AL, Zurbau A, Ho HVT, Vuksan V. The effects of gelled konjac glucomannan fibre on appetite and energy intake in healthy individuals: a randomised cross-over trial. Br J Nutr. 2018;119(1):109–16. doi:10.1017/S0007114517003233.
   PubMed Web of Science ®Google Scholar
• Huang CY, Zhang MY, Peng SS, Hong JR, Wang X, Jiang HJ, Zhang FL, Bai YX, Liang JZ, Yu YR, et al. Effect of Konjac food on blood glucose level in patients with diabetes. Biomed Environ Sci. 1990;3(2):123–31.
   PubMedGoogle Scholar
• Zhang MY, Huang CY, Wang X, Hong JR, Peng SS. The effect of foods containing refined Konjac meal on human lipid metabolism. Biomed Environ Sci. 1990;3(1):99–105.
   PubMedGoogle Scholar
• Ichihara K, Shima K, Nonaka K, Tarui S. Dietary therapy and insulin secretory response to glucose in adult-onset non-obese diabetic subjects. Endocrinol Jpn. 1975;22(5):399–408. doi:10.1507/endocrj1954.22.399.
   PubMedGoogle Scholar
• Brown A, Dornhorst A, McGowan B, et al. Low-energy total diet replacement intervention in patients with type 2 diabetes mellitus and obesity treated with insulin: a randomized trial. BMJ Open Diabetes Res Care. 2020;8:e001012. doi:10.1136/bmjdrc-2019-001012.
   PubMed Web of Science ®Google Scholar
• Tsuchimochi W, Ueno H, Yamashita E, Tsubouchi C, Sakoda H, Nakamura S, Nakazato M. Teneligliptin improves glycemic control with the reduction of postprandial insulin requirement in Japanese diabetic patients. Endocr J. 2015;62(1):13–20. doi:10.1507/endocrj.EJ14-0393.
   PubMed Web of Science ®Google Scholar
• Iwata M, Matsushita Y, Fukuda K, Wakura T, Okabe K, Koshimizu Y, Fukushima Y, Kobashi C, Yamazaki Y, Honoki H, et al. Secretory units of islets in transplantation index is a useful predictor of insulin requirement in Japanese type 2 diabetic patients. J Diabetes Invest. 2014;5(5):570–80. doi:10.1111/jdi.12181.
   PubMed Web of Science ®Google Scholar
• Yamada Y, Fukuda K, Fujimoto S, Hosokawa M, Tsukiyama K, Nagashima K, Fukushima M, Suzuki H, Toyoda K, Sassa M, et al. SUIT, secretory units of islets in transplantation: An index for therapeutic management of islet transplanted patients and its application to type 2 diabetes. Diabetes Res Clin Pract. 2006;74(3):222–6. doi:10.1016/j.diabres.2006.03.030.
   PubMed Web of Science ®Google Scholar
• Okura T, Nakamura R, Fujioka Y, Kawamoto-Kitao S, Ito Y, Matsumoto K, Shoji K, Sumi K, Matsuzawa K, Izawa S, et al. CPR-IR is an insulin resistance index that is minimally affected by hepatic insulin clearance-A preliminary research. PLoS One. 2018;13(5):e0197663. doi:10.1371/journal.pone.0197663.
   PubMed Web of Science ®Google Scholar
• Wallace TM, Levy JC, Matthews DR. Use and abuse of HOMA modeling. Diabetes Care. 2004;27(6):1487–95. doi:10.2337/diacare.27.6.1487.
   PubMed Web of Science ®Google Scholar
• https://www.dtu.ox.ac.uk/homacalculator/.
   Google Scholar
• Maeda N, Funahashi T, Matsuzawa Y, Shimomura I. Adiponectin, a unique adipocyte-derived factor beyond hormones. Atherosclerosis. 2020;292:1–9. doi:10.1016/j.atherosclerosis.2019.10.021.
   PubMed Web of Science ®Google Scholar
• Vazquez-Velasco M, Gonzalez-Torres L, Mendez MT, et al. Glucomannan and glucomannan plus spirulina-enriched squid-surimi added to high saturated diet affect glycemia, plasma and adipose leptin and adiponectin levels in growing Fa/Fa rats. Nutr Hosp. 2015;32:2718–24.
   PubMed Web of Science ®Google Scholar
• Zhai X, Lin D, Zhao Y, Li W, Yang X. Enhanced anti-obesity effects of bacterial cellulose combined with konjac glucomannan in high-fat diet-fed C57BL/6J mice. Food Funct. 2018;9(10):5260–72. doi:10.1039/c8fo01211c.
   PubMed Web of Science ®Google Scholar
• Wanders AJ, van den Borne JJGC, de Graaf C, Hulshof T, Jonathan MC, Kristensen M, Mars M, Schols HA, Feskens EJM. Effects of dietary fibre on subjective appetite, energy intake and body weight: a systematic review of randomized controlled trials. Obes Rev. 2011;12(9):724–39.
   PubMed Web of Science ®Google Scholar
• Clark MJ, Slavin JL. The effect of fiber on satiety and food intake: a systematic review. J Am Coll Nutr. 2013;32(3):200–11. doi:10.1080/07315724.2013.791194.
   PubMed Web of Science ®Google Scholar
• Vuksan V, Panahi S, Lyon M, Rogovik AL, Jenkins AL, Leiter LA. Viscosity of fiber preloads affects food intake in adolescents. Nutr Metab Cardiovasc Dis. 2009;19(7):498–503. doi:10.1016/j.numecd.2008.09.006.
   PubMed Web of Science ®Google Scholar
• Shang L, Wang Y, Ren Y, Ai T, Zhou P, Hu L, Wang L, Li J, Li B. In vitro gastric emptying characteristics of konjac glucomannan with different viscosity and its effects on appetite regulation. Food Funct. 2020;11(9):7596–610. doi:10.1039/d0fo01104e.
   PubMed Web of Science ®Google Scholar