Depression Severity, but Not Cognitive Impairment or Frailty, is Associated with Disability in Late-Life Depression

References

• Ahmed, N., Mandel, R., & Fain, M. J. (2007). Frailty: An emerging geriatric syndrome. The American Journal of Medicine, 120(9), 748–753. doi:10.1016/j.amjmed.2006.10.018
   PubMed Web of Science ®Google Scholar
• Alexopoulos, G. S., Kiosses, D. N., Klimstra, S., Kalayam, B., & Bruce, M. L. (2002). Clinical presentation of the “Depression–Executive Dysfunction Syndrome” of late life. The American Journal of Geriatric Psychiatry, 10(1), 98–106. doi:10.1097/00019442-200201000-00012
   PubMed Web of Science ®Google Scholar
• Andrews, G., Kemp, A., Sunderland, M., Von Korff, M., & Ustun, T. B. (2009). Normative data for the 12 item WHO disability assessment schedule 2.0. Plos One, 4(12), e8343. doi:10.1371/journal.pone.0008343
   PubMed Web of Science ®Google Scholar
• Benedict, R. H. (1997). Brief visuospatial memory test–Revised: Professional manual. Odessa, FL: PAR.
   Google Scholar
• Benton, A. L. (1983). Judgment of line orientation. New York, NY: Oxford University Press.
   Google Scholar
• Blazer, D. G. (2003). Depression in late life: Review and commentary. The Journals of Gerontology: Series A, 58(3), M249–M265. doi:10.1093/gerona/58.3.M249
   PubMed Web of Science ®Google Scholar
• Bohannon, R. W. (1997). Reference values for extremity muscle strength obtained by hand-held dynamometry from adults aged 20 to 79 years. Archives of Physical Medicine and Rehabilitation, 78(1), 26–32. doi:10.1016/S0003-9993(97)90005-8
   PubMed Web of Science ®Google Scholar
• Brandt, J. (1991). The Hopkins verbal learning test: Development of a new memory test with six equivalent forms. The Clinical Neuropsychologist, 5(2), 125–142. doi:10.1080/13854049108403297
   Google Scholar
• Brown, P. J., Rutherford, B. R., Yaffe, K., Tandler, J. M., Ray, J. L., Pott, E., … Roose, S. P. (2016). The depressed frail phenotype: The clinical manifestation of increased biological aging. The American Journal of Geriatric Psychiatry, 24(11), 1084–1094. doi:10.1016/j.jagp.2016.06.005
   PubMed Web of Science ®Google Scholar
• Bruce, M. L. (2001). Depression and disability in late life: Directions for future research. The American Journal of Geriatric Psychiatry, 9(2), 102–112. doi:10.1097/00019442-200105000-00003
   PubMed Web of Science ®Google Scholar
• Chau, R., Kissane, D. W., & Davison, T. E. (2019). Risk factors for depression in long-term care: A systematic review. Clinical Gerontologist, 42(3), 224–237. doi:10.1080/07317115.2018.1490371
   PubMed Web of Science ®Google Scholar
• Clegg, A., Young, J., Iliffe, S., Rikkert, M. O., & Rockwood, K. (2013). Frailty in elderly people. The Lancet, 381(9868), 752–762. doi:10.1016/S0140-6736(12)62167-9
   PubMed Web of Science ®Google Scholar
• Cole, M. G., & Dendukuri, N. (2003). Risk factors for depression among elderly community subjects: A systematic review and meta-analysis. American Journal of Psychiatry, 160(6), 1147–1156. doi:10.1176/appi.ajp.160.6.1147
   PubMed Web of Science ®Google Scholar
• Collard, R. M., Comijs, H. C., Naarding, P., & Oude Voshaar, R. C. (2014). Physical frailty: Vulnerability of patients suffering from late-life depression. Aging & Mental Health, 18(5), 570–578. doi:10.1080/13607863.2013.827628
   PubMed Web of Science ®Google Scholar
• Frances, A. (1994). Diagnostic and statistical manual of mental disorders: DSM-IV. Washington, D.C.: American Psychiatric Association.
   Google Scholar
• Fried, L. P., Tangen, C. M., Walston, J., Newman, A. B., Hirsch, C., Gottdiener, J., … McBurnie, M. A. (2001). Frailty in older adults: Evidence for a phenotype. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 56(3), M146–M157. doi:10.1093/gerona/56.3.M146
   PubMed Web of Science ®Google Scholar
• Fried, T. R., & Mor, V. (1997). Frailty and hospitalization of long-term stay nursing home residents. Journal of the American Geriatrics Society, 45(3), 265–269. doi:10.1111/jgs.1997.45.issue-3
   PubMed Web of Science ®Google Scholar
• Ganguli, M., Du, Y., Dodge, H. H., Ratcliff, G. G., & Chang, -C.-C. H. (2006). Depressive symptoms and cognitive decline in late life: A prospective epidemiological study. Archives of General Psychiatry, 63(2), 153–160. doi:10.1001/archpsyc.63.2.153
   PubMed Web of Science ®Google Scholar
• Golden, C., & Freshwater, S. (2002). Stroop color and word test, revised 2002 adult manual for clinical and experimental uses. Wood Dale, IL: Stoelting.
   Google Scholar
• Gonzales, M. M., Insel, P. S., Nelson, C., Tosun, D., Mattsson, N., Mueller, S. G., … Mackin, R. S. (2017). Cortical atrophy is associated with accelerated cognitive decline in mild cognitive impairment with subsyndromal depression. The American Journal of Geriatric Psychiatry, 25, 980–991. doi:10.1016/j.jagp.2017.04.011
   PubMed Web of Science ®Google Scholar
• Gould, C. E., Huh, J. T., Brunskill, S. R., McConnell, K., & Tenover, J. L. (2015). Disability and treatment outcomes for anxiety and depression in older veterans. Clinical Gerontologist, 38(4), 268–282. doi:10.1080/07317115.2015.1032463
   Web of Science ®Google Scholar
• Hamilton, M. (1960). A rating scale for depression. Journal of Neurology, Neurosurgery, and Psychiatry, 23(1), 56. doi:10.1136/jnnp.23.1.56
   PubMed Web of Science ®Google Scholar
• Iwasa, H., Gondo, Y., Yoshida, Y., Kwon, J., Inagaki, H., Kawaai, C., … Suzuki, T. (2008). Cognitive performance as a predictor of functional decline among the non-disabled elderly dwelling in a Japanese community: A 4-year population-based prospective cohort study. Archives of Gerontology and Geriatrics, 47(1), 139–149. doi:10.1016/j.archger.2007.07.008
   PubMed Web of Science ®Google Scholar
• Kiosses, D. N., & Alexopoulos, G. S. (2005). IADL functions, cognitive deficits, and severity of depression: A preliminary study. The American Journal of Geriatric Psychiatry, 13(3), 244–249. doi:10.1097/00019442-200503000-00010
   PubMed Web of Science ®Google Scholar
• Koenig, A. M., Bhalla, R. K., & Butters, M. A. (2014). Cognitive functioning and late-life depression. Journal of the International Neuropsychological Society, 20(5), 461–467. doi:10.1017/S1355617714000198
   PubMed Web of Science ®Google Scholar
• Kojima, G., Taniguchi, Y., Iliffe, S., & Walters, K. (2016). Frailty as a predictor of Alzheimer disease, vascular dementia, and all dementia among community-dwelling older people: A systematic review and meta-analysis. Journal of the American Medical Directors Association, 17(10), 881–888. doi:10.1016/j.jamda.2016.05.013
   PubMed Web of Science ®Google Scholar
• Luciano, J. V., Ayuso-Mateos, J. L., Aguado, J., Fernandez, A., Serrano-Blanco, A., Roca, M., & Haro, J. M. (2010). The 12-item World Health Organization Disability Assessment Schedule II (WHO-DAS II): A nonparametric item response analysis. BMC Medical Research Methodology, 10(1), 45. doi:10.1186/1471-2288-10-45
   PubMedGoogle Scholar
• Mackin, R. S., & Arean, P. A. (2009). Impaired financial capacity in late life depression is associated with cognitive performance on measures of executive functioning and attention. Journal of the International Neuropsychological Society, 15(5), 793–798. doi:10.1017/S1355617709990300
   PubMed Web of Science ®Google Scholar
• Mackin, R. S., Nelson, J. C., Delucchi, K. L., Raue, P. J., Satre, D. D., Kiosses, D. N., … Arean, P. A. (2014). Association of age at depression onset with cognitive functioning in individuals with late-life depression and executive dysfunction. The American Journal of Geriatric Psychiatry, 22(12), 1633–1641. doi:10.1016/j.jagp.2014.02.006
   PubMed Web of Science ®Google Scholar
• Mackin, R. S., Tosun, D., Mueller, S. G., Lee, J.-Y., Insel, P., Schuff, N., … Weiner, M. W. (2013). Patterns of reduced cortical thickness in late-life depression and relationship to psychotherapeutic response. The American Journal of Geriatric Psychiatry, 21(8), 794–802. doi:10.1016/j.jagp.2013.01.013
   PubMed Web of Science ®Google Scholar
• McGuire, L. C., Ford, E. S., & Ajani, U. A. (2006). Cognitive functioning as a predictor of functional disability in later life. The American Journal of Geriatric Psychiatry, 14(1), 36–42. doi:10.1097/01.JGP.0000192502.10692.d6
   PubMed Web of Science ®Google Scholar
• Mehta, K. M., Yaffe, K., & Covinsky, K. E. (2002). Cognitive impairment, depressive symptoms, and functional decline in older people. Journal of the American Geriatrics Society, 50(6), 1045–1050. doi:10.1046/j.1532-5415.2002.50259.x
   PubMed Web of Science ®Google Scholar
• Mezuk, B., Lohman, M., Dumenci, L., & Lapane, K. L. (2013). Are depression and frailty overlapping syndromes in mid- and late-life? A latent variable analysis. The American Journal of Geriatric Psychiatry, 21(6), 560–569. doi:10.1016/j.jagp.2012.12.019
   PubMed Web of Science ®Google Scholar
• Morin, R. T., Gonzales, M. M., Bickford, D., Catalinotto, D., Nelson, C., & Mackin, R. S. (2019). Impaired financial capacity in late-life depression: Revisiting associations with cognitive functioning. Journal of the International Neuropsychological Society, 25(10), 1088-1093.
   Web of Science ®Google Scholar
• Murray, C. J., Lopez, A. D., & Organization, W. H. (1996). The global burden of disease: A comprehensive assessment of mortality and disability from diseases, injuries, and risk factors in 1990 and projected to 2020: Summary. Boston, MA: Harvard University Press.
   Google Scholar
• Nie, N., Hull, C., & Bent, D. (2011). IBM statistical package for the social sciences (SPSS Version 20). Computer Software. Chicago, IL: SPSS.
   Google Scholar
• Penninx, B. W., Leveille, S., Ferrucci, L., van Eijk, J. T., & Guralnik, J. M. (1999). Exploring the effect of depression on physical disability: Longitudinal evidence from the established populations for epidemiologic studies of the elderly. American Journal of Public Health, 89(9), 1346–1352. doi:10.2105/AJPH.89.9.1346
   PubMed Web of Science ®Google Scholar
• Reitan, R., & Wolfson, D. (1993). The halstead-reitan neuropsychological battery. Theory and clinical interpretationNeuropsychology press. Tuscan, AZ: Neuropsychology Press.
   Google Scholar
• Rossier, P., & Wade, D. T. (2001). Validity and reliability comparison of 4 mobility measures in patients presenting with neurologic impairment. Archives of Physical Medicine and Rehabilitation, 82(1), 9–13. doi:10.1053/apmr.2001.9396
   PubMed Web of Science ®Google Scholar
• Scanlan, J. M., Binkin, N., Michieletto, F., Lessig, M., Zuhr, E., & Borson, S. (2007). Cognitive impairment, chronic disease burden, and functional disability: A population study of older Italians. The American Journal of Geriatric Psychiatry, 15(8), 716–724. doi:10.1097/01.JGP.0000260812.40317.6e
   PubMed Web of Science ®Google Scholar
• Smith, A. (1968). The symbol-digit modalities test: A neuropsychologic test of learning and other cerebral disorders. Learning Disorders, 83, 83–91.
   Google Scholar
• Uher, R., Perlis, R. H., Placentino, A., Dernovšek, M. Z., Henigsberg, N., Mors, O., … Farmer, A. (2012). Self-report and clinician-rated measures of depression severity: Can one replace the other? Depression and Anxiety, 29(12), 1043–1049. doi:10.1002/da.2012.29.issue-12
   PubMed Web of Science ®Google Scholar
• Vaughan, L., Corbin, A. L., & Goveas, J. S. (2015). Depression and frailty in later life: A systematic review. Clinical Interventions in Aging, 10, 1947. doi:10.2147/CIA.S69632
   PubMed Web of Science ®Google Scholar
• Wechsler, D. (1987). Wechsler memory scale-revised (WMS-R). San Antonio, TX: Psychological Corporation.
   Google Scholar
• Wechsler, D. (1997). Adult intelligence scale. New York, p. 21.
   Google Scholar
• Weyerer, S., Eifflaender-Gorfer, S., Köhler, L., Jessen, F., Maier, W., Fuchs, A., … Luppa, M. (2008). Prevalence and risk factors for depression in non-demented primary care attenders aged 75 years and older. Journal of Affective Disorders, 111(2–3), 153–163. doi:10.1016/j.jad.2008.02.008
   PubMed Web of Science ®Google Scholar