Could Frailty be an Explanatory Factor of the Association between Depression and Other Geriatric Syndromes in Later Life?

References

• Alexopoulos, G. S. (2019). Mechanisms and treatment of late-life depression. Translational Psychiatry, 9(1), 188. doi:10.1038/s41398-019-0514-6
   PubMedGoogle Scholar
• American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders: DSM-5 (5th ed.). Washington, DC: American Psychiatric Publishing.
   Google Scholar
• Aprahamian, I., Lin, S. M., Suemoto, C. K., Apolinario, D., Oiring de Castro Cezar, N., Elmadjian, S. M., … Yassuda, M. S. (2017). Feasibility and factor structure of the FRAIL scale in older adults. Journal of the American Medical Directors Association, 18(4), 367.e11–367.e18. doi:10.1016/j.jamda.2016.12.067
   Web of Science ®Google Scholar
• Atlantis, E., Shi, Z., Penninx, B. J., Wittert, G. A., Taylor, A., & Almeida, O. P. (2012). Chronic medical conditions mediate the association between depression and cardiovascular disease mortality. Social Psychiatry and Psychiatric Epidemiology, 47(4), 615–625. doi:10.1007/s00127-011-0365-9
   PubMed Web of Science ®Google Scholar
• Boult, C., Green, A. F., Boult, L. B., Pacala, J. T., Snyder, C., & Leff, B. (2009). Successful models of comprehensive care for older adults with chronic conditions: Evidence for the institute of medicine’s “retooling for an aging America” report. Journal of the American Geriatrics Society, 57(12), 2328–2337. doi:10.1111/j.1532-5415.2009.02571.x
   PubMed Web of Science ®Google Scholar
• Brandão, D. J., Fontenelle, L. F., da Silva, S. A., Menezes, P. R., & Pastor-Valero, M. (2019). Depression and excess mortality in the elderly living in low- and middle-income countries: Systematic review and meta-analysis. International Journal of Geriatric Psychiatry, 34(1), 22–30. doi:10.1002/gps.5008
   PubMed Web of Science ®Google Scholar
• Briggs, A. M., & Araujo de Carvalho, I. (2018). Actions required to implement integrated care for older people in the community using the World Health Organization’s ICOPE approach: A global Delphi consensus study. PLoS One, 13(10), e0205533. doi:10.1371/journal.pone.0205533
   PubMed Web of Science ®Google Scholar
• Brown, P. J., Rutherford, B. R., Yaffe, K., Tandler, J. M., Ray, J. L., Pott, E., … Roose, S. P. (2016). The depressed Frail phenotype: The clinical manifestation of increased biological aging. The American Journal of Geriatric Psychiatry, 24(11), 1084–1094. doi:10.1016/j.jagp.2016.06.005
   PubMed Web of Science ®Google Scholar
• Canevelli, M., Raganato, R., Remiddi, F., Quarata, F., Valletta, M., Bruno, G., & Cesari, M. (2020). Counting deficits or diseases? The agreement between frailty and multimorbidity in subjects with cognitive disturbances. Aging Clinical and Experimental Research, 32(1), 179–182. doi:10.1007/s40520-019-01161-2
   PubMed Web of Science ®Google Scholar
• Chu, W., Chang, S. F., Ho, H. Y., & Lin, H. C. (2019). The relationship between depression and frailty in community-dwelling older people: A systematic review and meta-analysis of 84,351 older adults. Journal of Nursing Scholarship, 51(5), 547–559. doi:10.1111/jnu.12501
   PubMed Web of Science ®Google Scholar
• Clegg, A., Young, J., Iliffe, S., Rikkert, M. O., & Rockwood, K. (2013). Frailty in elderly people. Lancet, 381(9868), 752–762. doi:10.1016/S0140-6736(12)62167-9
   PubMed Web of Science ®Google Scholar
• Collard, R. M., Arts, M., Comijs, H. C., Naarding, P., Verhaak, P. F., de Waal, M. W., & Oude Voshaar, R. C. (2015). The role of frailty in the association between depression and somatic comorbidity: Results from baseline data of an ongoing prospective cohort study. International Journal of Nursing Studies, 52(1), 188–196. doi:10.1016/j.ijnurstu.2014.07.007
   PubMed Web of Science ®Google Scholar
• Collard, R. M., Boter, H., Schoevers, R. A., & Oude Voshaar, R. C. (2012). Prevalence of frailty in community-dwelling older persons: A systematic review. Journal of the American Geriatrics Society, 60(8), 1487–1492. doi:10.1111/j.1532-5415.2012.04054.x
   PubMed Web of Science ®Google Scholar
• Cuijpers, P., Vogelzangs, N., Twisk, J., Kleiboer, A., Li, J., & Penninx, B. W. (2013). Differential mortality rates in major and subthreshold depression: Meta-analysis of studies that measured both. The British Journal of Psychiatry: The Journal of Mental Science, 202(1), 22–27. doi:10.1192/bjp.bp.112.112169
   PubMed Web of Science ®Google Scholar
• Cuijpers, P., Vogelzangs, N., Twisk, J., Kleiboer, A., Li, J., & Penninx, B. W. (2014). Comprehensive meta-analysis of excess mortality in depression in the general community versus patients with specific illnesses. American Journal of Psychiatry, 171(4), 453–462. doi:10.1176/appi.ajp.2013.13030325
   PubMed Web of Science ®Google Scholar
• de Groot, V., Beckerman, H., Lankhorst, G. J., & Bouter, L. M. (2003). How to measure comorbidity. a critical review of available methods. Journal of Clinical Epidemiology, 56(3), 221–229. doi:10.1016/s0895-4356(02)00585-1
   PubMed Web of Science ®Google Scholar
• Faller, J. W., Pereira, D., de Souza, S., Nampo, F. K., Orlandi, F. S., & Matumoto, S. (2019). Instruments for the detection of frailty syndrome in older adults: A systematic review. PLoS One, 14(4), e0216166. doi:10.1371/journal.pone.0216166
   PubMed Web of Science ®Google Scholar
• First, M. B., Williams, J. B. W., Karg, R. S., & Spitzer, R. L. (2016). Structured clinical interview for DSM-5 disorders, clinician version (SCID-5-CV). Arlington, VA: American Psychiatric Association.
   Google Scholar
• Flacker, J. M. (2003). What is a geriatric syndrome anyway? Journal of the American Geriatrics Society, 51(4), 574–576. doi:10.1046/j.1532-5415.2003.51174.x
   PubMed Web of Science ®Google Scholar
• Hoogendijk, E. O., Afilalo, J., Ensrud, K. E., Kowal, P., Onder, G., & Fried, L. P. (2019). Frailty: Implications for clinical practice and public health. Lancet, 394(10206), 1365–1375. doi:10.1016/S0140-6736(19)31786-6
   PubMed Web of Science ®Google Scholar
• Inouye, S. K., Studenski, S., Tinetti, M. E., & Kuchel, G. A. (2007). Geriatric syndromes: Clinical, research, and policy implications of a core geriatric concept. Journal of the American Geriatrics Society, 55(5), 780–791. doi:10.1111/j.1532-5415.2007.01156.x
   PubMed Web of Science ®Google Scholar
• Kojima, G., Iliffe, S., & Walters, K. (2018). Frailty index as a predictor of mortality: A systematic review and meta-analysis. Age and Ageing, 47(2), 193–200. doi:10.1093/ageing/afx162
   PubMed Web of Science ®Google Scholar
• Kroenke, K., Spitzer, R. L., & Williams, J. B. (2001). The PHQ-9: Validity of a brief depression severity measure. Journal of General Internal Medicine, 16(9), 606–613. doi:10.1046/j.1525-1497.2001.016009606.x
   PubMed Web of Science ®Google Scholar
• Levis, B., Benedetti, A., & Thombs, B. D.; DEPRESsion Screening Data (DEPRESSD) Collaboration. (2019). Accuracy of patient health questionnaire-9 (PHQ-9) for screening to detect major depression: Individual participant data meta-analysis. BMJ, 365, l1476. doi:10.1136/bmj.l1476
   PubMed Web of Science ®Google Scholar
• Liang, Y., Rausch, C., Laflamme, L., & Möller, J. (2018). Prevalence, trend and contributing factors of geriatric syndromes among older Swedes: Results from the Stockholm county council public health surveys. BMC Geriatrics, 18(1), 322. doi:10.1186/s12877-018-1018-6
   PubMedGoogle Scholar
• Lohman, M. C., Mezuk, B., & Dumenci, L. (2017). Depression and frailty: Concurrent risks for adverse health outcomes. Aging & Mental Health, 21(4), 399–408. doi:10.1080/13607863.2015.1102199
   PubMed Web of Science ®Google Scholar
• Luppa, M., Sikorski, C., Luck, T., Ehreke, L., Konnopka, A., Wiese, B., … Riedel-Heller, S. G. (2012). Age- and gender-specific prevalence of depression in latest-life–systematic review and meta-analysis. Journal of Affective Disorders, 136(3), 212–221. doi:10.1016/j.jad.2010.11.033
   PubMed Web of Science ®Google Scholar
• Marques, A., & Queirós, C. (2018). Frailty, sarcopenia and falls. In Hertz, K., & Sainty-Tomlinson, J. (Eds.). Fragility fracture nursing: Holistic care and management of the orthogeriatric patient (pp. 15–26). Chan, Switzerland: Springer International Publishing.
   Google Scholar
• Morley, J. E., Vellas, B., van Kan, G. A., Anker, S. D., Bauer, J. M., Bernabei, R., … Walston, J. (2013). Frailty consensus: A call to action. Journal of the American Medical Directors Association, 14(6), 392–397. doi:10.1016/j.jamda.2013.03.022
   PubMed Web of Science ®Google Scholar
• Nunes, B. P., Flores, T. R., Mielke, G. I., Thumé, E., & Facchini, L. A. (2016). Multimorbidity and mortality in older adults: A systematic review and meta-analysis. Archives of Gerontolology and Geriatrics, 67, 130–138. doi:10.1016/j.archger.2016.07.008
   PubMed Web of Science ®Google Scholar
• Penninx, B. W., Milaneschi, Y., Lamers, F., & Vogelzangs, N. (2013). Understanding the somatic consequences of depression: Biological mechanisms and the role of depression symptom profile. BMC Medicine, 11, 129. doi:10.1186/1741-7015-11-129
   PubMed Web of Science ®Google Scholar
• Prina, A. M., Huisman, M., Yeap, B. B., Hankey, G. J., Flicker, L., Brayne, C., & Almeida, O. P. (2013). Association between depression and hospital outcomes among older men. CMAJ: Canadian Medical Association Journal = Journal De l’Association Medicale Canadienne, 185(2), 117–123. doi:10.1503/cmaj.121171
   PubMed Web of Science ®Google Scholar
• Read, J. R., Sharpe, L., Modini, M., & Dear, B. F. (2017). Multimorbidity and depression: A systematic review and meta-analysis. Journal of Affective Disorders, 221, 36–46. doi:10.1016/j.jad.2017.06.009
   PubMed Web of Science ®Google Scholar
• Rockwood, K., & Mitnitski, A. (2007). Frailty in relation to the accumulation of deficits. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 62(7), 722–727. doi:10.1093/gerona/62.7.722
   PubMed Web of Science ®Google Scholar
• Salive, M. E. (2013). Multimorbidity in older adults. Epidemiologic Reviews, 35(1), 75–83. doi:10.1093/epirev/mxs009
   PubMed Web of Science ®Google Scholar
• Sánchez, E., Vidán, M. T., Serra, J. A., Fernández-Avilés, F., & Bueno, H. (2011). Prevalence of geriatric syndromes and impact on clinical and functional outcomes in older patients with acute cardiac diseases. Heart, 97(19), 1602–1606. doi:10.1136/hrt.2011.227504
   PubMed Web of Science ®Google Scholar
• Santos, I. S., Tavares, B. F., Munhoz, T. N., Almeida, L. S., Silva, N. T., Tams, B. D., … Matijasevich, A. (2013). Sensibilidade e especificidade do Patient Health Questionnaire-9 (PHQ-9) entre adultos da população geral [Sensitivity and specificity of the patient health questionnaire-9 (PHQ-9) among adults from the general population]. Cadernos De Saude Publica, 29(8), 1533–1543. doi:10.1590/0102-311x00144612
   PubMed Web of Science ®Google Scholar
• Soysal, P., Veronese, N., Thompson, T., Kahl, K. G., Fernandes, B. S., Prina, A. M., … Stubbs, B. (2017). Relationship between depression and frailty in older adults: A systematic review and meta-analysis. Ageing Research Reviews, 36, 78–87. doi:10.1016/j.arr.2017.03.005
   PubMed Web of Science ®Google Scholar
• Sternberg, S. A., Wershof Schwartz, A., Karunananthan, S., Bergman, H., & Mark Clarfield, A. (2011). The identification of frailty: A systematic literature review. Journal of the American Geriatrics Society, 59(11), 2129–2138. doi:10.1111/j.1532-5415.2011.03597.x
   PubMed Web of Science ®Google Scholar
• Vetrano, D. L., Palmer, K., Marengoni, A., Marzetti, E., Lattanzio, F., Roller-Wirnsberger, R., … Onder, G.; Joint Action ADVANTAGE WP4 Group. (2019). Frailty and multimorbidity: A systematic review and meta-analysis. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 74(5), 659–666.
   PubMed Web of Science ®Google Scholar
• Walston, J., Buta, B., & Xue, Q. L. (2018). Frailty screening and interventions: Considerations for clinical practice. Clinics in Geriatric Medicine, 34(1), 25–38. doi:10.1016/j.cger.2017.09.004
   PubMed Web of Science ®Google Scholar
• World Health Organization. (2019). Integrated care for older people (ICOPE): Guidance for person-centred assessment and pathways for primary care. Retrieved from https://apps.who.int/iris/handle/10665/326843
   Google Scholar