A Simple and Efficient Procedure for the Synthesis of an Alendronate- Oligonucleotide Conjugate via a Carbamate Linker

References

• Agrawal , S. and Zhao , Q. 1998 . Curr. Opin. Chem. Biol. , 2 : 519 – 528 . b) Crooke S. T., Biotechnol. Genet. Eng. Rev., (1998) 15, 121–157, c) Boggs R. T., Dean N. M., Encyclopedia of Human Biology, (1997) 2nd Ed., 1, 423–431.
   PubMed Web of Science ®Google Scholar
• Ho , P. T. C. and Parkinson , D. R. 1997 . Seminars in Oncology , 24 : 187 – 202 .
   PubMed Web of Science ®Google Scholar
• Giovannangeli , C. and Hélène , C. 1997 . Antisense Nucleic Acid Drug Dev. , 7 : 413 – 421 .
   PubMedGoogle Scholar
• Jaeger , L. 1997 . Curr. Opin. Struct. Biol. , 7 ( 3 ) : 324 – 335 .
   PubMed Web of Science ®Google Scholar
• Weiss , B. , Zhang , S. P. and Zhou , L. W. 1997 . Life Sci. , 60 ( 7 ) : 433 – 455 .
   PubMed Web of Science ®Google Scholar
• Lehenkari , P. , Hentunen , T. A. , Laitala-Leinonen , T. , Tuukkanen , J. and Vaananen , H. K. 1998 . Exp. Cell. Res. , 242 ( 1 ) : 128 – 137 .
   PubMed Web of Science ®Google Scholar
• Fleisch , H. 1998 . Endocr. Rev. , 19 ( 1 ) : 80 – 100 .
   PubMed Web of Science ®Google Scholar
• Siris , E. S. 1998 . J. Bone Miner. Res. , 13 ( 7 ) : 1061 – 1065 . b) Singer F. R., Minoofar P. N., Adv. Endocrinol. Metab., (1995) 6, 259–288, c) Papapoulos S. E., Baillieres, Clin. Endocrinol. Metab., (1997) 11(1), 117–143.
   PubMed Web of Science ®Google Scholar
• Shipman , C. M. , Croucher , P. I. , Russell , R. G. , Helfrich , M. H. and Rogers , M. J. 1998 . Cancer Res. , 58 ( 23 ) : 5294 – 5297 . b) Shipman C. M., Rogers M. J., Apperley J. F., Russell R. G., Croucher P. I., Br. J. Hematol., (1997) 98(3), 665–672, c) Henick K., Vescio R. A., Berenson J. R., Curr. Opin. Hematol, (1998) 5(4), 254–258.
   PubMed Web of Science ®Google Scholar
• Sasaki , A. , Kitamura , K. , Alcalde , R. E. , Tanaka , T. , Suzuki , A. , Etoh , Y. and Matsumura , T. 1998 . Int. J. Cancer , 77 ( 2 ) : 279 – 285 .
   PubMed Web of Science ®Google Scholar
• Fleisch , H. 1997 . Ann. Med. , 29 : 55 – 62 .
   PubMed Web of Science ®Google Scholar
• Nishikawa , M. , Akatsu , T. , Katayama , Y. , Yasutomo , Y. , Kado , S. , Kugal , N. , Yamamoto , M. and Nagata , N. 1996 . Bone , 18 ( 1 ) : 9 – 14 . b) Fleisch H., Medicina (B Aires), (1997) 57, Suppl 1, 65–67, c) Rodan G. A., Annu. Rev. Pharmacol. Toxicol., (1998) 38, 375–388.
   PubMed Web of Science ®Google Scholar
• Adami , S. and Zamberlan , N. 1996 . Drug Saf. , 14 ( 3 ) : 158 – 170 . b) Mondelo N., Peluffo V. A., Parma M. D., Cointry G. R., Capozza R. F., Ferretti J. L., Piccinni E., Montuori E., Medicina (B Aires) (1997) 57, 93–100
   PubMed Web of Science ®Google Scholar
• Golomb , G. , Ezra , A. , Hoffman , A. , Weiss , G. and Breuer , E. 1998 . XIV International Conference on Phosphorus Chemistry , Ohio, , USA : Cincinnati .
   Google Scholar
• Ylitalo , R. , Monkkonen , J. and Yla-Herttuala , S. 1998 . Life Sci. , 62 ( 5 ) : 413 – 422 .
   PubMed Web of Science ®Google Scholar
• Hnatowich , D. J. , Winnard , P. , Virzi , F. , Fogarasi , M. , Sano , T. , Smith , C. L. , Cantor , C. R. and Ruschowski , M. 1995 . J. Nucl. Med. , 36 ( 12 ) : 2306 – 2314 .
   PubMed Web of Science ®Google Scholar
• Hosain , F. , Spencer , R. P. , Couthon , M. H. and Sturtz , G. L. 1996 . J. Nucl. Med. , 37 ( 1 ) : 105 – 107 .
   PubMed Web of Science ®Google Scholar
• Wachter , L. , Jablonsky , J. A. and Ramachandran , K. L. 1986 . Nucleic Acids Res. , 14 : 7985 – 7994 .
   PubMed Web of Science ®Google Scholar
• Kieczykowski , G. R. , Jobson , R. B. , Melillo , D. G. , Reinhold , D. F. , Grenda , V. J. and Shinkai , I. 1995 . J. Org. Chem. , 60 : 8310 – 8312 .
   Web of Science ®Google Scholar
• Kumar , A. and Advani , S. 1992 . Nucleosides & Nucleotides , 11 : 999 – 1002 . b) Kumar A., Malhotra S., Nucleosides & Nucleotides, (1992) 11, 1003–1007.
   Web of Science ®Google Scholar
• Bethell , G. S. , Ayers , S. J. , Hancock , W. S. and Hearn , M. T. W. 1979 . J. Biol. Chem. , 254 : 2572 – 2574 . b) Bethell G. S., Ayers S. J., Hearn M. T. W., Hancock W. S., J. Chromatography, (1981) 219, 353–359, c) Hearn M. T. W., Harris E. L., Bethell G. S., Hancock W. S., Ayers S. J., J. Chromatography, (1981) 218, 509–518, d) Hearn M. T. W., Bethell G. S., Ayers S. J., Hancock W. S., J. Chromatography, (1979) 185, 463–470.
   PubMed Web of Science ®Google Scholar
• Dyba , M. , Jezowska-Bojscuck , M. , Kiss , E. , Kiss , T. , Kozlowski , H. , Leroux , Y. and El Manouni , D. 1996 . J. Chem. Soc., Dalton Trans. , : 1119 – 1123 .
   Google Scholar
• Shott , H. , Semmler , R. , Closs , K. and Eckstein , H. 1987 . Makromol. Chem. , 188 ( 6 ) : 1313 – 1346 .
   Web of Science ®Google Scholar
• Beaucage , S. L. and Caruthers , M. H. 1981 . Tetrahedron Lett. , 22 : 1859 – 1862 . b) Mc Bride L. J. Caruthers M. H. Tetrahedron Lett., (1983) 24, 245–248.
   Web of Science ®Google Scholar