Appendant structure plays an important role in amyloidogenic cystatin dimerization prior to domain swapping

References

• Abrahamson , M. 1996 . Molecular basis for amyloidosis related to hereditary brain hemorrhage . Scandinavian Journal of Clinical and Laboratory Investigation. Supplement , 226 : 47 – 56 .
   PubMedGoogle Scholar
• Arnold , K. , Bordoli , L. , Kopp , J. and Schwede , T. 2006 . The SWISS-MODEL workspace: A web-based environment for protein structure homology modelling . Bioinformatics , 22 : 195 – 201 .
   PubMed Web of Science ®Google Scholar
• Bjarnadottir , M. , Nilsson , C. , Lindstrom , V. , Westman , A. , Davidsson , P. , Thormodsson , F. , … and Grubb , A. 2001 . The cerebral hemorrhage-producing cystatin C variant (L68Q) in extracellular fluids . Amyloid , 8 : 1 – 10 .
   PubMed Web of Science ®Google Scholar
• Bode , W. , Engh , R. , Musil , D. , Thiele , U. , Huber , R. , Karshikov , A. , … and Turk , V. 1988 . The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases . EMBO Journal , 7 : 2593 – 2599 .
   PubMed Web of Science ®Google Scholar
• Bonvin , A.M. 2006 . Flexible protein-protein docking . Current Opinion in Structural Biology , 16 : 194 – 200 .
   PubMed Web of Science ®Google Scholar
• Calero , M. , Pawlik , M. , Soto , C. , Castano , E.M. , Sigurdsson , E.M. , Kumar , A. , … and Levy , E. 2001 . Distinct properties of wild-type and the amyloidogenic human cystatin C variant of hereditary cerebral hemorrhage with amyloidosis, Icelandic type . Journal of Neurochemistry , 77 : 628 – 637 .
   PubMed Web of Science ®Google Scholar
• Day , R. , Bennion , B.J. , Ham , S. and Daggett , V. 2002 . Increasing temperature accelerates protein unfolding without changing the pathway of unfolding . Journal of Molecular Biology , 322 : 189 – 203 .
   PubMed Web of Science ®Google Scholar
• Dobson , C.M. 1999 . Protein misfolding, evolution and disease . Trends in Biochemical Sciences , 24 : 329 – 332 .
   PubMed Web of Science ®Google Scholar
• Dobson , C.M. and Fersht , A.R. 1995 . Protein folding: A discussion , Cambridge : Cambridge University Press .
   Google Scholar
• Guex , N. and Peitsch , M.C. 1997 . SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling . Electrophoresis , 18 : 2714 – 2723 .
   PubMed Web of Science ®Google Scholar
• He , J. , Song , Y. , Ueyama , N. , Azakami , H. and Kato , A. 2005 . Characterization of recombinant amyloidogenic chicken cystatin mutant I66Q expressed in yeast . Journal of Biochemistry , 137 : 477 – 485 .
   PubMed Web of Science ®Google Scholar
• He , J. , Song , Y. , Ueyama , N. , Saito , A. , Azakami , H. and Kato , A. 2006 . Prevention of amyloid fibril formation of amyloidogenic chicken cystatin by site-specific glycosylation in yeast . Protein Science , 15 : 213 – 222 .
   PubMed Web of Science ®Google Scholar
• Humphrey , W. , Dalke , A. and Schulten , K. 1996 . VMD: Visual molecular dynamics . Journal of Molecular Graphics , 14 ( 33–38 ) : 27 – 38 .
   Google Scholar
• Ivanova , M.I. , Sawaya , M.R. , Gingery , M. , Attinger , A. and Eisenberg , D. 2004 . An amyloid-forming segment of β2-microglobulin suggests a molecular model for the fibril . Proceedings of the National Academy of Sciences of the United States of America , 101 : 10584 – 10589 .
   PubMed Web of Science ®Google Scholar
• Janowski , R. , Kozak , M. , Jankowska , E. , Grzonka , Z. , Grubb , A. , Abrahamson , M. and Jaskolski , M. 2001 . Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping . Natural Structural Biology , 8 : 316 – 320 .
   PubMedGoogle Scholar
• Jaskolski , M. 2001 . 3D domain swapping, protein oligomerization, and amyloid formation . Acta Biochimica Polonica , 48 : 807 – 827 .
   PubMed Web of Science ®Google Scholar
• Kabsch , W. and Sander , C. 1983 . Dictionary of protein secondary structure: Pattern recognition of hydrogen-bonded and geometrical features . Biopolymers , 22 : 2577 – 2637 .
   PubMed Web of Science ®Google Scholar
• Kaeser , S.A. , Herzig , M.C. , Coomaraswamy , J. , Kilger , E. , Selenica , M.L. , Winkler , D.T. , … and Jucker , M. 2007 . Cystatin C modulates cerebral β-amyloidosis . Nature Genetics , 39 : 1437 – 1439 .
   PubMed Web of Science ®Google Scholar
• Kolodziejczyk , R. , Michalska , K. , Hernandez-Santoyo , A. , Wahlbom , M. , Grubb , A. and Jaskolski , M. 2010 . Crystal structure of human cystatin C stabilized against amyloid formation . FEBS Journal , 277 : 1726 – 1737 .
   PubMed Web of Science ®Google Scholar
• Liu , H.L. , Lin , Y.M. , Zhao , J.H. , Hsieh , M.C. , Lin , H.Y. , Huang , C.H. , … and Chen , W.Y. 2007 . Molecular dynamics simulations of human cystatin C and its L68Q varient to investigate the domain swapping mechanism . Journal of Biomolecular Structure & Dynamics , 25 : 135 – 144 .
   PubMed Web of Science ®Google Scholar
• Liu , X. and Zhao , Y.P. 2009 . Donut-shaped fingerprint in homologous polypeptide relationships--a topological feature related to pathogenic structural changes in conformational disease . Journal of Theoretical Biology , 258 : 294 – 301 .
   PubMed Web of Science ®Google Scholar
• Liu , X. and Zhao , Y.P. 2010 . Switch region for pathogenic structural change in conformational disease and its prediction . PLoS ONE , 5 : e8441
   PubMed Web of Science ®Google Scholar
• Liu , X. and Zhao , Y.P. 2010 . Generating artificial homologous proteins according to the representative family character in molecular mechanics properties--an attempt in validating an underlying rule of protein evolution . FEBS Letters , 584 : 1059 – 1065 .
   PubMed Web of Science ®Google Scholar
• Massi , F. , Klimov , D. , Thirumalai , D. and Straub , J.E. 2002 . Charge states rather than propensity for β-structure determine enhanced fibrillogenesis in wild‐type Alzheimer’s β-amyloid peptide compared to E22Q Dutch mutant . Protein Science , 11 : 1639 – 1647 .
   PubMed Web of Science ®Google Scholar
• Olafsson , I. and Grubb , A. 2000 . Hereditary cystatin C amyloid angiopathy . Amyloid , 7 : 70 – 79 .
   PubMed Web of Science ®Google Scholar
• Revesz , T. , Ghiso , J. , Lashley , T. , Plant , G. , Rostagno , A. , Frangione , B. and Holton , J.L. 2003 . Cerebral amyloid angiopathies: A pathologic, biochemical, and genetic view . Journal of Neuropathology and Experimental Neurology , 62 : 885 – 898 .
   PubMed Web of Science ®Google Scholar
• Sanders , A. , Jeremy Craven , C. , Higgins , L.D. , Giannini , S. , Conroy , M.J. , Hounslow , A.M. , … and Staniforth , R.A. 2004 . Cystatin forms a tetramer through structural rearrangement of domain-swapped dimers prior to amyloidogenesis . Journal of Molecular Biology , 336 : 165 – 178 .
   PubMed Web of Science ®Google Scholar
• Szymańska , A. , Radulska , A. , Czaplewska , P. , Grubb , A. , Grzonka1 , Z. and Rodziewicz-Motowidło1 , S. 2009 . Governing the monomer-dimer ratio of human cystatin C by single amino acid substitution in the hinge region . Acta Biochimica Polonica , 56 : 455 – 463 .
   PubMed Web of Science ®Google Scholar
• Ventura , S. , Zurdo , J. , Narayanan , S. , Parreno , M. , Mangues , R. , Reif , B. , … and Serrano , L. 2004 . Short amino acid stretches can mediate amyloid formation in globular proteins: the Src homology 3 (SH3) case . Proceedings of the National Academy of Sciences of the United States of America , 101 : 7258 – 7263 .
   PubMed Web of Science ®Google Scholar
• Wahlbom , M. , Wang , X. , Lindstrom , V. , Carlemalm , E. , Jaskolski , M. and Grubb , A. 2007 . Fibrillogenic oligomers of human cystatin C are formed by propagated domain swapping . Journal of Biological Chemistry , 282 : 18318 – 18326 .
   PubMed Web of Science ®Google Scholar
• Yu , Y. , Wang , Y. , He , J. , Liu , Y. , Li , H. , Zhang , H. and Song , Y. 2010 . Structural and dynamic properties of a new amyloidogenic chicken cystatin mutant I108T . Journal of Biomolecular Structure & Dynamics , 27 : 641 – 649 .
   PubMed Web of Science ®Google Scholar