Tanreqing suppresses the proliferation and migration of non-small cell lung cancer cells by mediating the inactivation of the HIF1α signaling pathway via exosomal circ-WDR78

References

• Chen, W., Tang, D., Lin, J., Huang, X., Lin, S., Shen, G., & Dai, Y. (2022). Exosomal Circshkbp1 participates in non-small cell lung cancer progression through Pkm2-mediated glycolysis. Molecular Therapy Oncolytics, 24, 470–485. https://doi.org/10.1016/j.omto.2022.01.012
   PubMed Web of Science ®Google Scholar
• Chen, H.-H., Zhang, T.-N., Wu, Q.-J., Huang, X.-M., & Zhao, Y.-H. (2021). Circular RNAs in lung cancer: recent advances and future perspectives. Frontiers in Oncology, 11, 664290. https://doi.org/10.3389/fonc.2021.664290
   PubMed Web of Science ®Google Scholar
• Chi, Y., Luo, Q., Song, Y., Yang, F., Wang, Y., Jin, M., & Zhang, D. (2019). Circular RNA Circpip5k1a promotes non-small cell lung cancer proliferation and metastasis through Mir-600/Hif-1α regulation. Journal of Cellular Biochemistry, 120(11), 19019–19030. https://doi.org/10.1002/jcb.29225
   PubMed Web of Science ®Google Scholar
• Cui, B., & Yu, J. M. (2018). Autophagy: A new pathway for traditional Chinese medicine. Journal of Asian Natural Products Research, 20(1), 14–26. https://doi.org/10.1080/10286020.2017.1374948
   PubMed Web of Science ®Google Scholar
• Ding, X.-C., Wang, L.-L., Zhang, X.-D., Xu, J.-L., Li, P.-F., Liang, H., Zhang, X.-B., Xie, L., Zhou, Z.-H., Yang, J., Weichselbaum, R. R., Yu, J.-M., & Hu, M. (2021). The relationship between expression of Pd-L1 and Hif-1α in glioma cells under hypoxia. Journal of Hematology & Oncology, 14(1), 92. https://doi.org/10.1186/s13045-021-01102-5
   PubMed Web of Science ®Google Scholar
• He, Q., Zhao, L., Liu, X., Zheng, J., Liu, Y., Liu, L., Ma, J., Cai, H., Li, Z., & Xue, Y. (2019). Mov10 binding Circ-Dicer1 regulates the angiogenesis of glioma via Mir-103a-3p/Mir-382-5p mediated Zic4 expression change. Journal of Experimental & Clinical Cancer Research: CR, 38(1), 9. https://doi.org/10.1186/s13046-018-0990-1
   PubMedGoogle Scholar
• He, Y.-Q., Zhou, C.-C., Deng, J.-L., Wang, L., & Chen, W.-S. (2021). Tanreqing inhibits LPS-induced acute lung injury in vivo and in vitro through downregulating sting signaling pathway. Frontiers in Pharmacology, 12, 746964. https://doi.org/10.3389/fphar.2021.746964
   PubMedGoogle Scholar
• Hua, Q., Mi, B., Xu, F., Wen, J., Zhao, L., Liu, J., & Huang, G. (2020). Hypoxia-induced lncRNA-Ac020978 promotes proliferation and glycolytic metabolism of non-small cell lung cancer by regulating Pkm2/Hif-1α axis. Theranostics, 10(11), 4762–4778. https://doi.org/10.7150/thno.43839
   PubMed Web of Science ®Google Scholar
• Janbandhu, V., Tallapragada, V., Patrick, R., Li, Y., Abeygunawardena, D., Humphreys, D. T., Martin, E. M. M. A., Ward, A. O., Contreras, O., Farbehi, N., Yao, E., Du, J., Dunwoodie, S. L., Bursac, N., & Harvey, R. P. (2022). Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction. Cell Stem Cell, 29(2), 281–297.e12. https://doi.org/10.1016/j.stem.2021.10.009
   PubMed Web of Science ®Google Scholar
• Le, T. D., Zhang, J., Liu, L., & Li, J. (2017). Computational methods for identifying miRNA sponge interactions. Briefings in Bioinformatics, 18(4), 577–590. https://doi.org/10.1093/bib/bbw042
   PubMed Web of Science ®Google Scholar
• Lei, Y., et al. (2013). Protective effect of tanreqing injection on acute hepatic injury induced by CCL4 in rats. Zhongguo Zhong Yao Za Zhi, 38(8), 1226–1230. Print.
   PubMedGoogle Scholar
• Li, Z., Feiyue, Z., & Gaofeng, L. (2021). Traditional Chinese medicine and lung cancer – From theory to practice. Biomedicine & Pharmacotherapy = Biomedecine & pharmacotherapie, 137, 111381. https://doi.org/10.1016/j.biopha.2021.111381
   PubMed Web of Science ®Google Scholar
• Li, Y., Feng, W., Kong, M., Liu, R., Wu, A., Shen, L., Tang, Z., & Wang, F. (2021). Exosomal circRNAs: A new star in cancer. Life Sciences, 269, 119039. https://doi.org/10.1016/j.lfs.2021.119039
   PubMed Web of Science ®Google Scholar
• Lin, F., Chen, H.-W., Zhao, G.-A., Li, Y., He, X.-H., Liang, W.-Q., Shi, Z.-L., Sun, S.-Y., Tian, P.-P., Huang, M.-Y., & Liu, C. (2020). Advances in research on the circRNA-miRNA-mRNA network in coronary heart disease treated with traditional chinese medicine. Evidence-Based Complementary and Alternative Medicine: ECAM, 2020, 8048691–8048610. https://doi.org/10.1155/2020/8048691
   PubMed Web of Science ®Google Scholar
• Liu, H., Ding, X.-F., Guo, R., Zhao, M.-F., Deng, D., Hao, Y., & Wang, Y. (2020). Effects and safety of tanreqing injection on viral pneumonia: A protocol for systematic review and meta-analysis. Medicine, 99(35), e21808. https://doi.org/10.1097/MD.0000000000021808
   PubMed Web of Science ®Google Scholar
• Li, T.-M., Yu, Y.-H., Tsai, F.-J., Cheng, C.-F., Wu, Y.-C., Ho, T.-J., Liu, X., Tsang, H., Lin, T.-H., Liao, C.-C., Huang, S.-M., Li, J.-P., Lin, J.-C., Lin, C.-C., Liang, W.-M., & Lin, Y.-J. (2018). Characteristics of chinese herbal medicine usage and its effect on survival of lung cancer patients in Taiwan. Journal of Ethnopharmacology, 213, 92–100. https://doi.org/10.1016/j.jep.2017.10.031
   PubMed Web of Science ®Google Scholar
• Li, J., Zhang, G., Liu, C.-G., Xiang, X., Le, M. T. N., Sethi, G., Wang, L., Goh, B.-C., & Ma, Z. (2022). The potential role of exosomal circRNAs in the tumor microenvironment: insights into cancer diagnosis and therapy. Theranostics, 12(1), 87–104. https://doi.org/10.7150/thno.64096
   PubMed Web of Science ®Google Scholar
• Magalhães, L., Ribeiro-Dos-Santos, A. M., Cruz, R. L., Nakamura, K. D. D M., Brianese, R., Burbano, R., Ferreira, S. P., Oliveira, E. L. F. D., Anaissi, A. K. M., Nahúm, M. C. D S., Demachki, S., Vidal, A. F., Carraro, D. M., & Ribeiro-Dos-Santos, Â. (2022). Triple-negative breast cancer circrnaome reveals Hsa_Circ_0072309 as a potential risk biomarker. Cancers, 14(13), 3280.) https://doi.org/10.3390/cancers14133280
   PubMed Web of Science ®Google Scholar
• Ma, X., Wang, C., Chen, J., Wei, D., Yu, F., & Sun, J. (2021). Circagfg1 sponges Mir-28-5p to promote non-small-cell lung cancer progression through modulating Hif-1α level. Open Medicine (Warsaw, Poland), 16(1), 703–717. https://doi.org/10.1515/med-2021-0269
   PubMedGoogle Scholar
• Ma, M., Yang, X. X., Zhang, J., Zhao, L. M., Liu, L. H., Shan, B. E. (2015). Effect of tanreqing injection on immune activity of peripheral blood lymphocytes of patients with lung cancer. Zhongguo Zhong Yao Za Zhi, 40(6), 1207–1211.
   PubMedGoogle Scholar
• Ma, M., Zhao, L., Yang, X., Liu, L., Zhang, J., Shan, B. (2015). Tanreqing injection promotes the immune function of mice with Lewis lung carcinoma after chemotherapy. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi, 31(3), 297–301.
   PubMedGoogle Scholar
• Pan, X., Zhang, X., Sun, H., Zhang, J., Yan, M., & Zhang, H. (2013). Autophagy inhibition promotes 5-fluorouraci-induced apoptosis by stimulating ROS formation in human non-small cell lung cancer A549 cells. PloS One, 8(2), e56679. https://doi.org/10.1371/journal.pone.0056679
   PubMed Web of Science ®Google Scholar
• Su, X.-L., Wang, J.-W., Che, H., Wang, C.-F., Jiang, H., Lei, X., Zhao, W., Kuang, H.-X., & Wang, Q.-H. (2020). Clinical application and mechanism of traditional Chinese medicine in treatment of lung cancer. Chinese Medical Journal, 133(24), 2987–2997. https://doi.org/10.1097/CM9.0000000000001141
   PubMed Web of Science ®Google Scholar
• Sui, X., Liu, Z., Niu, L., Yin, B., & Huo, C. (2022). Hsa_Circ_0006677 regulates special at-rich binding protein-2-mediated tumor-suppressive effect via functioning as a mir-1245a sponge in non-small cell lung cancer. Bioengineered, 13(2), 3760–3774. https://doi.org/10.1080/21655979.2022.2031400
   PubMed Web of Science ®Google Scholar
• Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2021). Global Cancer Statistics 2020: Globocan estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 71(3), 209–249. https://doi.org/10.3322/caac.21660
   PubMed Web of Science ®Google Scholar
• Tong, Y., Wen, J., Yang, T., Li, H., Wei, S., Jing, M., Wang, M., Zou, W., & Zhao, Y. (2021). Clinical efficacy and safety of tanreqing injection combined with antibiotics versus antibiotics alone in the treatment of pulmonary infection patients after chemotherapy with lung cancer: A systematic review and meta-analysis. Phytotherapy Research: PTR, 35(1), 122–137. https://doi.org/10.1002/ptr.6790
   PubMed Web of Science ®Google Scholar
• Wang, C., et al. (2018). LncRNA Pvt1 regulate expression of Hif1α via functioning as ceRNA for Mir‑199a‑5p in non‑small cell lung cancer under hypoxia. Mol Med Rep, 17(1), 1105–1110.
   PubMed Web of Science ®Google Scholar
• Wang, C., Tan, S., Li, J., Liu, W.-R., Peng, Y., & Li, W. (2020). CircRNAs in lung cancer – Biogenesis, function and clinical implication. Cancer Letters, 492, 106–115. https://doi.org/10.1016/j.canlet.2020.08.013
   PubMed Web of Science ®Google Scholar
• Wang, S., Wang, Z., Wu, Y., Hou, C., Dai, X., Wang, Q., Wu, Y., Qian, C., & Zhang, X. (2022). The TCM prescription Yi-Fei-Jie-Du-Tang inhibit invasive migration and EMT of lung cancer cells by activating autophagy. Evidence-Based Complementary and Alternative Medicine: ECAM, 2022, 9160616. https://doi.org/10.1155/2022/9160616
   PubMedGoogle Scholar
• Wen, C., Wang, H., Wu, X., He, L., Zhou, Q., Wang, F., Chen, S., Huang, L., Chen, J., Wang, H., Ye, W., Li, W., Yang, X., Liu, H., & Peng, J. (2019). ROS-mediated inactivation of the Pi3k/Akt pathway is involved in the antigastric cancer effects of thioredoxin reductase-1 inhibitor chaetocin. Cell Death & Disease, 10(11), 809. https://doi.org/10.1038/s41419-019-2035-x
   PubMedGoogle Scholar
• Wu, Q., Zhou, X., Li, P., Ding, M., You, S., Xu, Z., Ye, J., Chen, X., Tan, M., Wang, J., Wang, W., & Qiu, J. (2021). Roc1 promotes the malignant progression of bladder cancer by regulating P-Iκbα/Nf-Κb signaling. Journal of Experimental & Clinical Cancer Research: CR, 40(1), 158. https://doi.org/10.1186/s13046-021-01935-5
   PubMed Web of Science ®Google Scholar
• Xie, H., Yao, J., Wang, Y., & Ni, B. (2022). Exosome-transmitted circvmp1 facilitates the progression and cisplatin resistance of non-small cell lung cancer by targeting Mir-524-5p-Mettl3/Sox2 axis. Drug Delivery, 29(1), 1257–1271. https://doi.org/10.1080/10717544.2022.2057617
   PubMed Web of Science ®Google Scholar
• Xu, X., Tao, R., Sun, L., & Ji, X. (2020). Exosome-transferred Hsa_Circ_0014235 promotes DDP chemoresistance and deteriorates the development of non-small cell lung cancer by mediating the Mir-520a-5p/Cdk4 pathway. Cancer Cell International, 20(1), 552. https://doi.org/10.1186/s12935-020-01642-9
   PubMed Web of Science ®Google Scholar
• Yan, D., Dong, W., He, Q., Yang, M., Huang, L., Kong, J., Qin, H., Lin, T., & Huang, J. (2019). Circular RNA circpicalm sponges Mir-1265 to inhibit bladder cancer metastasis and influence Fak phosphorylation. EBioMedicine, 48, 316–331. https://doi.org/10.1016/j.ebiom.2019.08.074
   PubMed Web of Science ®Google Scholar
• Yang, B., Lu, X-C., Zhang, F., Liu, Y., & Zhu, H-L (2011). Inhibitory effects of traditional Chinese herbal medicine tanreqing injection on proliferation of leukemia cells in vitro and the potential mechanisms. Zhong xi yi jie he xue bao = Journal of Chinese Integrative Medicine, 9(4), 414–422. https://doi.org/10.3736/jcim20110411
   PubMedGoogle Scholar
• Yang, B., Teng, F., Chang, L., Wang, J., Liu, D.-L., Cui, Y.-S., & Li, G.-H. (2021). Tumor-derived exosomal circRNA_102481 contributes to EGFR-TKIS resistance via the Mir-30a-5p/Ror1 axis in non-small cell lung cancer. Aging, 13(9), 13264–13286. https://doi.org/10.18632/aging.203011
   PubMedGoogle Scholar
• Ye, L., Jia, Y., Ji, K. E., Sanders, A. J., Xue, K., Ji, J., Mason, M. D., & Jiang, W. G. (2015). Traditional Chinese medicine in the prevention and treatment of cancer and cancer metastasis. Oncology Letters, 10(3), 1240–1250. https://doi.org/10.3892/ol.2015.3459
   PubMed Web of Science ®Google Scholar
• Yu, Y.-Y., Zhu, Y.-J., Zou, Y., Xiao, Z.-Z., Shi, S., Liu, Y.-H., Chang, X.-S., Chen, Y.-D., & Zhang, H.-B. (2021). Qing-Kai-Ling injection acts better than Shen-Fu injection in enhancing the antitumor effect of gefitinib in resistant non-small cell lung cancer models. Evidence-Based Complementary and Alternative Medicine: ECAM, 2021, 9911935. https://doi.org/10.1155/2021/9911935
   PubMed Web of Science ®Google Scholar
• Zappa, C., & Mousa, S. A. (2016). Non-small cell lung cancer: current treatment and future advances. Translational Lung Cancer Research, 5(3), 288–300. https://doi.org/10.21037/tlcr.2016.06.07
   PubMed Web of Science ®Google Scholar
• Zhang, J., Han, L., Yu, J., Li, H., & Li, Q. (2021). Mir-224 aggravates cancer-associated fibroblast-induced progression of non-small cell lung cancer by modulating a positive loop of the Sirt3/Ampk/Mtor/Hif-1α axis. Aging, 13(7), 10431–10449.) https://doi.org/10.18632/aging.202803
   PubMedGoogle Scholar
• Zheng, Z., Hong, D., Zhang, X., Chang, Y., Sun, N., Lin, Z., Li, H., Huang, S., Zhang, R., Xie, Q., Huang, H., & Jin, H. (2021). Uc.77 downregulation promotes colorectal cancer cell proliferation by inhibiting Fbxw8-mediated Cdk4 protein degradation. Frontiers in Oncology, 11, 673223. https://doi.org/10.3389/fonc.2021.673223
   PubMed Web of Science ®Google Scholar
• Zhu, C., Xie, Y., Li, Q., Zhang, Z., Chen, J., Zhang, K., Xia, X., Yu, D., Chen, D., Yu, Z., & Chen, J. (2023). Cpsf6-mediated Xbp1 3'UTR shortening attenuates cisplatin-induced ER stress and elevates chemo-resistance in lung adenocarcinoma. Drug Resistance Updates: Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy, 68, 100933. https://doi.org/10.1016/j.drup.2023.100933
   PubMed Web of Science ®Google Scholar