The Vagus Nerve and the Celiaco-mesenteric Ganglia Participate in the Feeding Responses Evoked by Non-sulfated Cholecystokinin-8 in Male Sprague Dawley Rats

References

• Sayegh AI. The role of cholecystokinin receptors in the short-term control of food intake. Prog Mol Biol Transl Sci. 2013;114:277–316. doi:10.1016/B978-0-12-386933-3.00008-X.
   PubMed Web of Science ®Google Scholar
• Beinfeld MC. Biosynthesis and processing of pro CCK: recent progress and future challenges. Life Sci. 2003;72:747–757. doi:10.1016/s0024-3205(02)02330-5.
   PubMed Web of Science ®Google Scholar
• Wank SA, Pisegna JR, de Weerth A. Cholecystokinin receptor family. Molecular cloning, structure, and functional expression in rat, guinea pig, and human. Ann N Y Acad Sci. 1994;713:49–66. doi:10.1111/j.1749-6632.1994.tb44052.x.
   PubMed Web of Science ®Google Scholar
• Gibbs J, Young RC, Smith GP. Cholecystokinin decreases food intake in rats. J Comp Physiol Psychol. 1973;84:488–495. doi:10.1037/h0034870.
   PubMed Web of Science ®Google Scholar
• Corwin RL, Gibbs J, Smith GP. Increased food intake after type A but not type B cholecystokinin receptor blockade. Physiol Behav. 1991;50:255–258. doi:10.1016/0031-9384(91)90529-W.
   PubMed Web of Science ®Google Scholar
• Dafalla AI, Mhalhal TR, Washington MC, et al. Non-sulfated cholecystokinin-8 reduces meal size and prolongs the intermeal interval in male Sprague Dawley rats. Neuropeptides. 2019 Feb;73:57-65. doi:10.1016/j.npep.2018.11.003. Epub 2018 Nov 13.
   Google Scholar
• Smith GP, Jerome C, Cushin BJ, Eterno R, Simansky KJ. Abdominal vagotomy blocks the satiety effect of cholecystokinin in the rat. Science. 1981;213:1036–1037. doi:10.1126/science.7268408.
   PubMed Web of Science ®Google Scholar
• Brown TA, Washington MC, Metcalf SA, Sayegh AI. The feeding responses evoked by cholecystokinin are mediated by vagus and splanchnic nerves. Peptides. 2011;32:1581–1586. doi:10.1016/j.peptides.2011.06.024.
   PubMed Web of Science ®Google Scholar
• Altschuler SM, Escardo J, Lynn RB, Miselis RR. The central organization of the vagus nerve innervating the colon of the rat. Gastroenterology. 1993;104:502–509. doi:10.1016/0016-5085(93)90419-d.
   PubMed Web of Science ®Google Scholar
• Shapiro RE, Miselis RR. The central organization of the vagus nerve innervating the stomach of the rat. J Comp Neurol. 1985;238:473–488. doi:10.1002/cne.902380411.
   PubMed Web of Science ®Google Scholar
• Quinson N, Robbins HL, Clark MJ, Furness JB. Locations and innervation of cell bodies of sympathetic neurons projecting to the gastrointestinal tract in the rat. Arch Histol Cytol. 2001;64:281–294.
   PubMedGoogle Scholar
• Isomura G, Iwata S, Chiba M, Shimizu N. Constitution of the greater splanchnic nerve in the rat. Anatomischer Anz. 1985;159:159–171.
   PubMedGoogle Scholar
• Hermes SM, Andresen MC, Aicher SA. Localization of TRPV1 and P2X3 in unmyelinated and myelinated vagal afferents in the rat. J Chem Neuroanat. 2016;72:1–7. doi:10.1016/j.jchemneu.2015.12.003.
   PubMed Web of Science ®Google Scholar
• Adelson DW, Wei JY, Yashar M,TJOL, Tache Y. Central autonomic activation by intracisternal TRH analogue excites gastric splanchnic afferent neurons. J Neurophysiol. 1999;81:682–691. doi:10.1152/jn.1999.81.2.682.
   PubMed Web of Science ®Google Scholar
• Broberger C, Holmberg K, Shi TJ, Dockray G, Hokfelt T. Expression and regulation of cholecystokinin and cholecystokinin receptors in rat nodose and dorsal root ganglia. Brain Res. 2001;903:128–140. doi:10.1016/s0006-8993(01)02468-4.
   PubMed Web of Science ®Google Scholar
• Widdop RE, Krstew E, Mercer LD, Carlberg M, Beart PM, Jarrott B. Electrophysiological and autoradiographical evidence for cholecystokinin A receptors on rat isolated nodose ganglia. J Auton Nerv Syst. 1994;46:65–73. doi:10.1016/0165-1838(94)90145-7.
   PubMedGoogle Scholar
• Corp ES, McQuade J, Moran TH, Smith GP. Characterization of type A and type B CCK receptor binding sites in rat vagus nerve. Brain Res. 1993;623:161–166. doi:10.1016/0006-8993(93)90024-h.
   PubMed Web of Science ®Google Scholar
• Monnikes H, Lauer G, Arnold R. Peripheral administration of cholecystokinin activates c-fos expression in the locus coeruleus/subcoeruleus nucleus, dorsal vagal complex and paraventricular nucleus via capsaicin-sensitive vagal afferents and CCK-A receptors in the rat. Brain Res. 1997;770:277–288. doi:10.1016/S0006-8993(97)00865-2.
   PubMed Web of Science ®Google Scholar
• Bhatnagar S, Viau V, Chu A, Soriano L, Meijer OC, Dallman MF. A cholecystokinin-mediated pathway to the paraventricular thalamus is recruited in chronically stressed rats and regulates hypothalamic-pituitary-adrenal function. J Neurosci. 2000;20:5564–5573.
   PubMed Web of Science ®Google Scholar
• Gwynne RM, Bornstein JC. Local inhibitory reflexes excited by mucosal application of nutrient amino acids in guinea pig jejunum. Am J Physiol Gastrointestinal Liver Physiol. 2007;292:G1660–1670. doi:10.1152/ajpgi.00580.2006.
   PubMed Web of Science ®Google Scholar
• Dafalla AI, Mhalhal TR, Hiscocks K, Heath J, Sayegh AI. Non-sulfated cholecystokinin-8 increases enteric and hindbrain Fos-like immunoreactivity in male Sprague Dawley rats. Brain Res. 2019;1708:200–206. doi:10.1016/j.brainres.2018.12.019.
   PubMed Web of Science ®Google Scholar
• Hunt JV, Washington MC, Sayegh AI. Exenatide and feeding: possible peripheral neuronal pathways. Peptides. 2012;33:285–290. doi:10.1016/j.peptides.2011.12.009.
   PubMed Web of Science ®Google Scholar
• Wright SA, Washington MC, Garcia C, Sayegh AI. Gastrin releasing peptide-29 requires vagal and splanchnic neurons to evoke satiation and satiety. Peptides. 2012;33:125–131. doi:10.1016/j.peptides.2011.12.004.
   PubMed Web of Science ®Google Scholar
• Washington MC, Williams K, Sayegh AI. The feeding responses evoked by endogenous cholecystokinin are regulated by different gastrointestinal sites. Horm Behav. 2016;78:79–85. doi:10.1016/j.yhbeh.2015.10.019.
   PubMed Web of Science ®Google Scholar
• Dafalla AI, Mhalhal TR, Washington MC, et al. Non-sulfated cholecystokinin-8 reduces meal size and prolongs the intermeal interval in male Sprague Dawley rats. Neuropeptides. 2019;73:57–65. doi:10.1016/j.npep.2018.11.003.
   PubMed Web of Science ®Google Scholar
• Mhalhal TR, Washington MC, Newman K, Heath JC, Sayegh AI. Exogenous glucagon-like peptide-1 reduces body weight and cholecystokinin-8 enhances this reduction in diet-induced obese male rats. Physiol Behav. 2017;179:191–199. doi:10.1016/j.physbeh.2017.06.011.
   PubMed Web of Science ®Google Scholar
• Mhalhal TR, Washington MC, Newman K, Heath JC, Sayegh AI. Infusion of exogenous cholecystokinin-8, gastrin releasing peptide-29 and their combination reduce body weight in diet-induced obese male rats. Appetite. 2017;109:172–181. doi:10.1016/j.appet.2016.12.001.
   PubMed Web of Science ®Google Scholar
• Shively J, Reeve JR Jr., Eysselein VE, Ben-Avram C, Vigna SR, Walsh JH. CCK-5: sequence analysis of a small cholecystokinin from canine brain and intestine. Am J Physiol. 1987;252:G272–275.
   PubMedGoogle Scholar
• Rehfeld JF, Agersnap M. Unsulfated cholecystokinin: an overlooked hormone? Regul Pept. 2012;173:1–5. doi:10.1016/j.regpep.2011.09.009.
   PubMedGoogle Scholar
• Reubi JC, Koefoed P, Hansen T, et al. Procholecystokinin as marker of human Ewing sarcomas. Clin Cancer Res. 2004;10:5523–5530. doi:10.1158/1078-0432.CCR-1015-03.
   PubMed Web of Science ®Google Scholar
• Mazur M, Furgala A, Jablonski K, Mach T, Thor P. Autonomic nervous system activity in constipation-predominant irritable bowel syndrome patients. Medical science monitor: international medical. J Exp Clin Res. 2012;18:CR493–499.
   Google Scholar
• Kasimay O, Cakir B, Devseren E, Yegen BC. Exogenous melatonin delays gastric emptying rate in rats: role of CCK2 and 5-HT3 receptors. J Physiol Pharmacol. 2005;56:543–553.
   PubMed Web of Science ®Google Scholar
• Portincasa P, Di Ciaula A, vanBerge-Henegouwen GP. Smooth muscle function and dysfunction in gallbladder disease. Curr Gastroenterol Rep. 2004;6:151–162.
   PubMedGoogle Scholar
• Takahashi T, Owyang C. Mechanism of cholecystokinin-induced relaxation of the rat stomach. J Auton Nerv Syst. 1999;75:123–130. doi:10.1016/s0165-1838(98)00181-7.
   PubMedGoogle Scholar
• Giuliani S, Lippe IT, Maggi CA, Meli A. Dual effects of cholecystokinin-octapeptide on duodenal motility of urethane-anesthetized rats. J Pharmacol Exp Ther. 1990;252:1312–1317.
   PubMed Web of Science ®Google Scholar
• Wickbom J, Herrington MK, Permert J, Jansson A, Arnelo U. Gastric emptying in response to IAPP and CCK in rats with subdiaphragmatic afferent vagotomy. Regul Pept. 2008;148:21–25. doi:10.1016/j.regpep.2008.03.010.
   PubMedGoogle Scholar
• Young A. Inhibition of gastric emptying. Adv Pharmacol. 2005;52:99–121. doi:10.1016/S1054-3589(05)52006-4.
   PubMedGoogle Scholar
• Raybould HE, Holzer HH. Duodenal acid-induced inhibition of gastric motility and emptying in rats. Am J Physiol. 1993;265:G540–546. doi:10.1152/ajpgi.1993.265.3.G540.
   PubMedGoogle Scholar
• Lin CW, Miller TR, Both CCK-A. CCK-B/gastrin receptors are present on rabbit vagus nerve. Am J Physiol. 1992;263:R591–595. doi:10.1152/ajpregu.1992.263.3.R591.
   PubMedGoogle Scholar
• Mercer JG, Lawrence CB. Selectivity of cholecystokinin (CCK) receptor antagonists, MK-329 and L-365,260, for axonally-transported CCK binding sites on the rat vagus nerve. Neurosci Lett. 1992;137:229–231. doi:10.1016/0304-3940(92)90410-9.
   PubMed Web of Science ®Google Scholar
• Branchereau P, Bohme GA, Champagnat J, et al. CholecystokininA and cholecystokininB receptors in neurons of the brainstem solitary complex of the rat: pharmacological identification. J Pharmacol Exp Ther. 1992;260:1433–1440.
   PubMed Web of Science ®Google Scholar
• Zhang J, Ritter RC. Circulating GLP-1 and CCK-8 reduce food intake by capsaicin-insensitive, nonvagal mechanisms. Am J Physiol Regul Integr Comp Physiol. 2012;302:R264–273. doi:10.1152/ajpregu.00114.2011.
   PubMed Web of Science ®Google Scholar
• Raybould HE, Gayton RJ, Dockray GJ. Mechanisms of action of peripherally administered cholecystokinin octapeptide on brain stem neurons in the rat. J Neurosci. 1988;8:3018–3024.
   PubMed Web of Science ®Google Scholar
• Washington MC, Sayegh AI. Gastrin releasing peptides increase Fos-like immunoreactivity in the enteric nervous system and the dorsal vagal complex. Peptides. 2011;32:1600–1605. doi:10.1016/j.peptides.2011.06.023.
   PubMed Web of Science ®Google Scholar
• Abbott CR, Monteiro M, Small CJ, et al. The inhibitory effects of peripheral administration of peptide YY(3–36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway. Brain Res. 2005;1044:127–131. doi:10.1016/j.brainres.2005.03.011.
   PubMed Web of Science ®Google Scholar
• South EH, Ritter RC. Capsaicin application to central or peripheral vagal fibers attenuates CCK satiety. Peptides. 1988;9:601–612. doi:10.1016/0196-9781(88)90171-4.
   PubMed Web of Science ®Google Scholar
• Knoper SR, Meehan AG, Purnyn S, Coggan JS, Anthony TL, Kreulen DL. CCKA receptors mediate slow depolarizations in cultured mammalian sympathetic neurons. Eur J Pharmacol. 1993;232:65–69. doi:10.1016/0014-2999(93)90729-2.
   PubMed Web of Science ®Google Scholar
• Hokfelt T, Holmberg K, Shi TJ, Broberger C. CCK-ergic mechanisms in sensory systems. Scand J Clin Lab Invest Suppl. 2001;234:69–74.
   PubMedGoogle Scholar
• Smith GP. Cholecystokinin and treatment of meal size: proof of principle. Obesity. 2006;14(Suppl 4):168S–170S. doi:10.1038/oby.2006.300.
   PubMedGoogle Scholar
• Gulley S, Sharma SK, Moran TH, Sayegh AI. Cholecystokinin-8 increases Fos-like immunoreactivity in the brainstem and myenteric neurons of rats through CCK1 receptors. Peptides. 2005;26:1617–1622. doi:10.1016/j.peptides.2005.02.020.
   PubMed Web of Science ®Google Scholar
• Raboin SJ, Reeve JR Jr., Cooper MS, Green GM, Sayegh AI. Activation of submucosal but not myenteric plexus of the gastrointestinal tract accompanies reduction of food intake by camostat. Regul Pept. 2008;150:73–80. doi:10.1016/j.regpep.2008.06.007.
   PubMedGoogle Scholar
• Sayegh AI, Washington MC, Johnson RE, et al. Celiac and the cranial mesenteric arteries supply gastrointestinal sites that regulate meal size and intermeal interval length via cholecystokinin-58 in male rats. Horm Behav. 2015;67:48–53. doi:10.1016/j.yhbeh.2014.11.011.
   PubMed Web of Science ®Google Scholar
• Berthoud HR, Patterson LM. Anatomical relationship between vagal afferent fibers and CCK-immunoreactive entero-endocrine cells in the rat small intestinal mucosa. Acta Anat. 1996;156:123–131. doi:10.1159/000147837.
   PubMedGoogle Scholar
• Berthoud HR, Kressel M, Raybould HE, Neuhuber WL. Vagal sensors in the rat duodenal mucosa: distribution and structure as revealed by in vivo DiI-tracing. Anat Embryol. 1995;191:203–212. doi:10.1007/bf00187819.
   PubMedGoogle Scholar
• Dafalla AI, Mhalhal TR, Hiscocks K, Heath J, Sayegh AI. Non-sulfated cholecystokinin-8 increases enteric and hindbrain Fos-like immunoreactivity in male Sprague Dawley rats. Brain Res. 2019 Apr 1;1708:200-206. doi:10.1016/j.brainres.2018.12.019. Epub 2018 Dec 17.
   Google Scholar
• Washington MC, Mhalhal TR, Sayegh AI. Cholecystokinin-33, but not cholecystokinin-8 shows gastrointestinal site specificity in regulating feeding behaviors in male rats. Horm Behav. 2016;85:36–42. doi:10.1016/j.yhbeh.2016.08.002.
   PubMed Web of Science ®Google Scholar
• Williams KE, Washington MC, Johnson-Rouse T, et al. Exogenous glucagon-like peptide-1 acts in sites supplied by the cranial mesenteric artery to reduce meal size and prolong the intermeal interval in rats. Appetite. 2016;96:254–259. doi:10.1016/j.appet.2015.09.030.
   PubMed Web of Science ®Google Scholar
• Washington MC, Aglan AH, Sayegh AI. The stomach and/or upper duodenum contain sites of action that control meal size and intermeal interval length by exogenous rat gastrin releasing peptide. Peptides. 2014;55:41–46. doi:10.1016/j.peptides.2014.02.004.
   PubMed Web of Science ®Google Scholar
• Bucinskaite V, Kurosawa M, Lundeberg T. Exogenous cholecystokinin-8 reduces vagal efferent nerve activity in rats through CCK(A) receptors. Br J Pharmacol. 2000;129:1649–1654. doi:10.1038/sj.bjp.0703270.
   PubMed Web of Science ®Google Scholar
• Monnikes H, Lauer G, Bauer C, Tebbe J, Zittel TT, Arnold R. Pathways of Fos expression in locus ceruleus, dorsal vagal complex, and PVN in response to intestinal lipid. Am J Physiol. 1997;273:R2059–2071. doi:10.1152/ajpregu.1997.273.6.R2059.
   PubMedGoogle Scholar
• Gay J, Fioramonti J, Garcia-Villar R, Bueno L. Enhanced intestinal motor response to cholecystokinin in post-Nippostrongylus brasiliensis-infected rats: modulation by CCK receptors and the vagus nerve. Neurogastroenterol Motil Off J Eur Gastrointestinal Motil Soc. 2001;13:155–162.
   PubMed Web of Science ®Google Scholar
• Ma KT, Si JQ, Zhang ZQ, et al. Modulatory effect of CCK-8S on GABA-induced depolarization from rat dorsal root ganglion. Brain Res. 2006;1121:66–75. doi:10.1016/j.brainres.2006.08.094.
   PubMed Web of Science ®Google Scholar
• Aras HC, Ekstrom J. Cholecystokinin- and gastrin-induced protein and amylase secretion from the parotid gland of the anaesthetized rat. Regul Pept. 2006;134:89–96. doi:10.1016/j.regpep.2006.01.004.
   PubMedGoogle Scholar
• Storr M, Sattler D, Hahn A, Schusdziarra V, Allescher HD. Endogenous CCK depresses contractile activity within the ascending myenteric reflex pathway of rat ileum. Neuropharmacology. 2003;44:524–532. doi:10.1016/s0028-3908(03)00028-5.
   PubMed Web of Science ®Google Scholar