2,017
Views
3
CrossRef citations to date
0
Altmetric
Neurology

Red cell distribution width: a novel predictive biomarker for stroke risk after transient ischaemic attack

, , , , , , , , & show all
Pages 1167-1177 | Received 05 Nov 2021, Accepted 24 Mar 2022, Published online: 26 Apr 2022

References

  • Rothwell PM, Warlow CP. Timing of TIAs preceding stroke: time window for prevention is very short. Neurology. 2005;64(5):817–820.
  • Rothwell PM, Giles MF, Chandratheva A, et al. Effect of urgent treatment of transient ischaemic attack and minor stroke on early recurrent stroke (EXPRESS study): a prospective population-based sequential comparison. Lancet. 2007;370(9596):1432–1442.
  • Johnston SC, Rothwell PM, Nguyen-Huynh MN, et al. Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack. Lancet. 2007;369(9558):283–292.
  • Amarenco P, Labreuche J, Lavallée PC, et al. Does ABCD2 score below 4 allow more time to evaluate patients with a transient ischemic attack? Stroke. 2009;40(9):3091–3095.
  • Amarenco P, Labreuche J, Lavallee PC. Patients with transient ischemic attack with ABCD2 < 4 can have similar 90-day stroke risk as patients with transient ischemic attack with ABCD2 >/=4. Stroke. 2012;43:863–865.
  • NIHCE. Stroke and transient ischaemic attack in over 16s: diagnosis and initial management. London (UK); National Institute for Health and Care Excellence; 2019.
  • Rodriguez-Castro E, Hervella P, Lopez-Dequidt I, et al. NT-pro-BNP: a novel predictor of stroke risk after transient ischemic attack. Int J Cardiol. 2020;298:93–97.
  • Li J, Wang Y, Lin J, et al. Soluble CD40L is a useful marker to predict future strokes in patients with minor stroke and transient ischemic attack. Stroke. 2015;46(7):1990–1992.
  • Berthet C, Lei H, Gruetter R, et al. Early predictive biomarkers for lesion after transient cerebral ischemia. Stroke. 2011;42(3):799–805.
  • Li J, Wang Y. Blood biomarkers in minor stroke and transient ischemic attack. Neurosci Bull. 2016;32(5):463–468.
  • Guan L, Wang Y, Claydon VE, et al. Autonomic parameter and stress profile predict secondary ischemic events after transient ischemic attack or minor stroke. Stroke. 2019;50(8):2007–2015.
  • Kim J, Kim YD, Song TJ, et al. Red blood cell distribution width is associated with poor clinical outcome in acute cerebral infarction. Thromb Haemost. 2012;108(08):349–356.
  • Wang L, Wang C, Wu S, et al. Red blood cell distribution width is associated with mortality after acute ischemic stroke: a cohort study and systematic review. Ann Transl Med. 2020;8(4):81.
  • Zhao Z, Liu T, Li J, et al. Elevated red cell distribution width level is associated with oxidative stress and inflammation in a canine model of rapid atrial pacing. Int J Cardiol. 2014;174(1):174–176.
  • Cherubini A, Ruggiero C, Polidori MC, et al. Potential markers of oxidative stress in stroke. Free Radic Biol Med. 2005;39(7):841–852.
  • Chamorro A, Dirnagl U, Urra X, et al. Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation. Lancet Neurol. 2016;15(8):869–881.
  • Amarenco P. Transient ischemic Attack. N Engl J Med. 2020;382(20):1933–1941.
  • Goldstein LB, Jones MR, Matchar DB, et al. Improving the reliability of stroke subgroup classification using the trial of ORG 10172 in acute stroke treatment (TOAST) criteria. Stroke. 2001;32(5):1091–1098.
  • Clarke K, Sagunarthy R, Kansal S. RDW as an additional marker in inflammatory bowel disease/undifferentiated colitis. Dig Dis Sci. 2008;53(9):2521–2523.
  • Xie KH, Liu LL, Su CY, et al. Low antioxidant status of serum uric acid, bilirubin, albumin, and creatinine in patients with benign paroxysmal positional vertigo. Front Neurol. 2020;11:601695.
  • Lappegard J, Ellingsen TS, Skjelbakken T, et al. Red cell distribution width is associated with future risk of incident stroke. The Tromsø Study. Thromb Haemost. 2016;115(1):126–134.
  • Hong RH, Zhu J, Li ZZ, et al. Red blood cell distribution width is associated with neuronal damage in acute ischemic stroke. Aging. 2020;12(10):9855–9867.
  • Wang C, Wang L, Zhong D, et al. Association between red blood cell distribution width and hemorrhagic transformation in acute ischemic stroke patients. Cerebrovasc Dis. 2019;48(3–6):193–199.
  • Pinho J, Marques SA, Freitas E, et al. Red cell distribution width as a predictor of 1-year survival in ischemic stroke patients treated with intravenous thrombolysis. Thromb Res. 2018;164:4–8.
  • Saliba W, Barnett-Griness O, Elias M, et al. The association between red cell distribution width and stroke in patients with atrial fibrillation. Am J Med. 2015;128:192–198.
  • Peng YF, Pan GG. Red blood cell distribution width predicts homocysteine levels in adult population without vitamin B12 and folate deficiencies. Int J Cardiol. 2017;227:8–10.
  • Lorente L, Martin MM, Abreu-Gonzalez P, et al. Early mortality of brain infarction patients and red blood cell distribution width. Brain Sci. 2020;10(4):196.
  • Semba RD, Patel KV, Ferrucci L, et al. Serum antioxidants and inflammation predict red cell distribution width in older women: the women’s health and aging study I. Clin Nutr. 2010;29(5):600–604.
  • Wang X, Lo EH. Triggers and mediators of hemorrhagic transformation in cerebral ischemia. Mol Neurobiol. 2003;28(3):229–244.
  • Wang J, Zhang P, Tang Z. Animal models of transient ischemic attack: a review. Acta Neurol Belg. 2020;120(2):267–275.
  • Warner DS, Sheng H, Batinić-Haberle I. Oxidants, antioxidants and the ischemic brain. J Exp Biol. 2004;207(18):3221–3231.
  • McCormick MT, Muir KW, Gray CS, et al. Management of hyperglycemia in acute stroke: how, when, and for whom? Stroke. 2008;39(7):2177–2185.
  • Arnao V, Salemi G, Scondotto S, et al. Stroke incidence and case fatality: a 9-year prospective population-based study in an elderly population of bagheria, Italy. Neurol Sci. 2021;42(6):2447–2452.
  • Hollander M, Koudstaal PJ, Bots ML, et al. Incidence, risk, and case fatality of first ever stroke in the elderly population. The Rotterdam Study. J Neurol Neurosurg Psychiatry. 2003;74(3):317–321.
  • Rosenzweig S, Carmichael ST. Age-dependent exacerbation of white matter stroke outcomes: a role for oxidative damage and inflammatory mediators. Stroke. 2013;44(9):2579–2586.
  • Patel KV, Ferrucci L, Ershler WB, et al. Red blood cell distribution width and the risk of death in middle-aged and older adults. Arch Intern Med. 2009;169(5):515–523.
  • Stoll G, Bendszus M. Inflammation and atherosclerosis: novel insights into plaque formation and destabilization. Stroke. 2006;37(7):1923–1932.
  • van der Spuy WJ, Pretorius E. Interrelation between inflammation, thrombosis, and neuroprotection in cerebral ischemia. Rev Neurosci. 2012;23(3):269–278.
  • Anrather J, Iadecola C. Inflammation and stroke: an overview. Neurotherapeutics. 2016;13(4):661–670.
  • Ramiro L, Simats A, Garcia-Berrocoso T, et al. Inflammatory molecules might become both biomarkers and therapeutic targets for stroke management. Ther Adv Neurol Disord. 2018;11:1756286418789340.
  • Segal HC, Burgess AI, Poole DL, et al. Population-based study of blood biomarkers in prediction of subacute recurrent stroke. Stroke. 2014;45(10):2912–2917.
  • Ansari FA, Ali SN, Mahmood R. Sodium nitrite-induced oxidative stress causes membrane damage, protein oxidation, lipid peroxidation and alters major metabolic pathways in human erythrocytes. Toxicol in Vitro. 2015;29(7):1878–1886.
  • Pierce CN, Larson DF. Inflammatory cytokine inhibition of erythropoiesis in patients implanted with a mechanical circulatory assist device. Perfusion. 2005;20(2):83–90.
  • Lippi G, Targher G, Montagnana M, et al. Relation between red blood cell distribution width and inflammatory biomarkers in a large cohort of unselected outpatients. Arch Pathol Lab Med. 2009;133(4):628–632.
  • Ahmad H, Khan M, Laugle M, et al. Red cell distribution width is positively correlated with atherosclerotic cardiovascular disease 10-Year risk score, age, and CRP in spondyloarthritis with axial or peripheral disease. Int J Rheumatol. 2018;2018:2476239.
  • de Gonzalo-Calvo D, de Luxan-Delgado B, Rodriguez-Gonzalez S, et al. Interleukin 6, soluble tumor necrosis factor receptor I and red blood cell distribution width as biological markers of functional dependence in an elderly population: a translational approach. Cytokine. 2012;58(2):193–198.
  • Crimi E, Ignarro LJ, Napoli C. Microcirculation and oxidative stress. Free Radic Res. 2007;41(12):1364–1375.
  • Kaul DK, Koshkaryev A, Artmann G, et al. Additive effect of red blood cell rigidity and adherence to endothelial cells in inducing vascular resistance. Am J Physiol Heart Circ Physiol. 2008;295(4):H1788–H1793.
  • Tikhomirova IA, Oslyakova AO, Mikhailova SG. Microcirculation and blood rheology in patients with cerebrovascular disorders. Clin Hemorheol Microcirc. 2011;49(1–4):295–305.
  • Yedgar S, Koshkaryev A, Barshtein G. The red blood cell in vascular occlusion. Pathophysiol Haemost Thromb. 2002;32(5–6):263–268.
  • Hong L, Fang K, Ling Y, et al. Red blood cell distribution width is associated with collateral flow and final infarct volume in acute stroke with large artery atherosclerosis. Semin Thromb Hemost. 2020;46(4):502–506.
  • Lappegard J, Ellingsen TS, Vik A, et al. Red cell distribution width and carotid atherosclerosis progression. The Tromsø Study. Thromb Haemost. 2015;113(3):649–654.