1,898
Views
0
CrossRef citations to date
0
Altmetric
Dermatology

Mediation roles of neutrophils and high-density lipoprotein (HDL) on the relationship between HLA-DQB1 and rosacea

, , , , , , & show all
Pages 1530-1537 | Received 20 Oct 2021, Accepted 10 May 2022, Published online: 27 May 2022

References

  • van Zuuren EJ. Rosacea. N Engl J Med. 2017;377(18):1530–1764.
  • Deng Y, Peng Q, Yang S, et al. The rosacea-specific quality-of-Life instrument (RosQol): revision and validation among Chinese patients. PLoS One. 2018;13(2):e0192487.
  • Gallo RL, Granstein RD, Kang S, et al. Standard classification and pathophysiology of rosacea: the 2017 update by the national rosacea society expert committee. J Am Acad Dermatol. 2018;78(1):148–155.
  • Thiboutot D, Anderson R, Cook-Bolden F, et al. Standard management options for rosacea: the 2019 update by the national rosacea society expert committee. J Am Acad Dermatol. 2020;82(6):1501–1510.
  • Li J, Wang B, Deng Y, et al. Epidemiological features of rosacea in Changsha, China: a population-based, cross-sectional study. J Dermatol. 2020;47(5):497–502.
  • Two AM, Wu W, Gallo RL, et al. Rosacea: part I. Introduction, categorization, histology, pathogenesis, and risk factors. J Am Acad Dermatol. 2015;72(5):749–758. quiz 59–60.
  • Abram K, Silm H, Maaroos HI, et al. Risk factors associated with rosacea. J Eur Acad Dermatol Venereol. 2010;24(5):565–571.
  • Steinhoff M, Schauber J, Leyden JJ. New insights into rosacea pathophysiology: a review of recent findings. J Am Acad Dermatol. 2013;69(6 Suppl 1):S15–S26.
  • Elsaie ML, Choudhary S. Updates on the pathophysiology and management of acne rosacea. Postgrad Med. 2009;121(5):178–186.
  • Aldrich N, Gerstenblith M, Fu P, et al. Genetic vs environmental factors that correlate with rosacea: a cohort-based survey of twins. JAMA Dermatol. 2015;151(11):1213–1219.
  • Awosika O, Oussedik E. Genetic predisposition to rosacea. Dermatol Clin. 2018;36(2):87–92.
  • Aponte JL, Chiano MN, Yerges-Armstrong LM, et al. Assessment of rosacea symptom severity by genome-wide association study and expression analysis highlights immuno-inflammatory and skin pigmentation genes. Hum Mol Genet. 2018;27(15):2762–2772.
  • Chang ALS, Raber I, Xu J, et al. Assessment of the genetic basis of rosacea by genome-wide association study. J Invest Dermatol. 2015;135(6):1548–1555.
  • Mayadas T, Cullere X, Lowell C. The multifaceted functions of neutrophils. Annu Rev Pathol. 2014;9:181–218.
  • Chen Q, Shi X, Tang Y, et al. Association between rosacea and cardiometabolic disease: a systematic review and meta-analysis. J Am Acad Dermatol. 2020;83(5):1331–1340.
  • Hua T, Chung P, Chen Y, et al. Cardiovascular comorbidities in patients with rosacea: a nationwide case-control study from Taiwan. J Am Acad Dermatol. 2015;73(2):249–254.
  • Duman N, Ersoy Evans S, Atakan N. Rosacea and cardiovascular risk factors: a case control study. J Eur Acad Dermatol Venereol. 2014;28(9):1165–1169.
  • Akin Belli A, Kara A, Ozbas Gok S. Can hematologic parameters be an indicator of metabolic disorders accompanying rosacea? Acta Dermatovenerol Croat. 2017;25(2):145–150.
  • Akin Belli A, Ozbas Gok S, Akbaba G, et al. The relationship between rosacea and insulin resistance and metabolic syndrome. Eur J Dermatol. 2016;26(3):260–264.
  • Hirt P, Castillo D, Yosipovitch G, et al. Skin changes in the obese patient. J Am Acad Dermatol. 2019;81(5):1037–1057.
  • Yang F, Sun L, Zhu X, et al. Identification of new genetic variants of HLA-DQB1 associated with human longevity and lipid homeostasis-a cross-sectional study in a Chinese population. Aging (Albany NY). 2017;9(11):2316–2333.
  • Rosenson R, Brewer H, Ansell B, et al. Dysfunctional HDL and atherosclerotic cardiovascular disease. Nat Rev Cardiol. 2016;13(1):48–60.
  • Lewington S, Whitlock G, Clarke R, et al. Blood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths. Lancet. 2007;370(9602):1829–1839.
  • Ridker P. LDL cholesterol: controversies and future therapeutic directions. Lancet. 2014;384(9943):607–617.
  • Baigent C, Blackwell L, Emberson J, et al. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet. 2010;376:1670–1681.
  • Mihaylova B, Emberson J, Blackwell L, et al. The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials. Lancet. 2012;380:581–590.
  • Tawakol A, Fayad Z, Mogg R, et al. Intensification of statin therapy results in a rapid reduction in atherosclerotic inflammation: results of a multicenter fluorodeoxyglucose-positron emission tomography/computed tomography feasibility study. J Am Coll Cardiol. 2013;62(10):909–917.
  • Toms T, Panoulas V, Smith J, et al. Rheumatoid arthritis susceptibility genes associate with lipid levels in patients with rheumatoid arthritis. Ann Rheum Dis. 2011;70(6):1025–1032.
  • Davis L, Whitfield E, Cannon G, et al. Association of rheumatoid arthritis susceptibility gene with lipid profiles in patients with rheumatoid d arthritis. Rheumatology (Oxford). 2014;53(6):1014–1021.
  • Bobryshev Y, Andreeva E, Mikhailova I, et al. Correlation between lipid deposition, immune-inflammatory cell content and MHC class II expression in diffuse intimal thickening of the human aorta. Atherosclerosis. 2011;219(1):171–183.
  • Nikpay M, McPherson R. Convergence of biomarkers and risk factor trait loci of coronary artery disease at 3p21.31 and HLA region. NPJ Genom Med. 2021;6(1):12.
  • Wilkin J, Dahl M, Detmar M, et al. Standard grading system for rosacea: report of the national rosacea society expert committee on the classification and staging of rosacea. J Am Acad Dermatol. 2004;50(6):907–912.
  • Taieb A, Khemis A, Ruzicka T, Ivermectin Phase III Study Group, et al. Maintenance of remission following successful treatment of Papulopustular rosacea with Ivermectin 1% cream vs. metronidazole 0.75% cream: 36-week extension of the ATTRACT randomized study. J Eur Acad Dermatol Venereol. 2016;30(5):829–836.
  • Zhang S, Zhou X, Zhou X, et al. Subtype-specific inherited predisposition to pemphigus in the Chinese population. Br J Dermatol. 2019;180(4):828–835.
  • Čierny D, Lehotský J, Kantorová E, et al. The HLA-DRB1 and HLA-DQB1 alleles are associated with multiple sclerosis disability progression in Slovak population. Neurol Res. 2018;40(7):607–614.
  • Ramgopal S, Rathika C, Padma Malini R, et al. Critical amino acid variations in HLA-DQB1* molecules confers susceptibility to autoimmune thyroid disease in South India. Genes Immun. 2019;20(1):32–38.
  • Buddenkotte J, Steinhoff M. Recent advances in understanding and managing rosacea. F1000Res. 2018;7:1885. F1000 Faculty Rev-
  • Buhl T, Sulk M, Nowak P, et al. Molecular and morphological characterization of inflammatory infiltrate in rosacea reveals activation of Th1/Th17 pathways. J Invest Dermatol. 2015;135(9):2198–2208.
  • Bertino B, Blanchet-Réthoré S, Thibaut de Ménonville S, et al. Brimonidine displays anti-inflammatory properties in the skin through the modulation of the vascular barrier function. Exp Dermatol. 2018;27(12):1378–1387.
  • Fernandez-Obregon A, Patton D. The role of Chlamydia pneumoniae in the etiology of acne rosacea: response to the use of oral azithromycin. Cutis. 2007;79:163–167.
  • Miyachi Y, Imamura S, Niwa Y. Anti-oxidant action of metronidazole: a possible mechanism of action in rosacea. Br J Dermatol. 1986;114(2):231–234.
  • Matsushima H, Geng S, Lu R, et al. Neutrophil differentiation into a unique hybrid population exhibiting dual phenotype and functionality of neutrophils and dendritic cells. Blood. 2013;121(10):1677–1689.
  • Oehler L, Majdic O, Pickl W, et al. Neutrophil granulocyte-committed cells can be driven to acquire dendritic cell characteristics. J Exp Med. 1998;187(7):1019–1028.
  • Vono M, Lin A, Norrby-Teglund A, et al. Neutrophils acquire the capacity for antigen presentation to memory CD4+ T cells in vitro and ex vivo. Blood. 2017;129(14):1991–2001.
  • Radsak M, Iking-Konert C, Stegmaier S, et al. Polymorphonuclear neutrophils as accessory cells for T-cell activation: major histocompatibility complex class II restricted antigen-dependent induction of T-cell proliferation. Immunology. 2000;101(4):521–530.
  • Iking-Konert C, Vogt S, Radsak M, et al. Polymorphonuclear neutrophils in Wegener's granulomatosis acquire characteristics of antigen presenting cells. Kidney Int. 2001;60(6):2247–2262.
  • Benachour H, Zaiou M, Samara A, et al. Association of human cathelicidin (hCAP-18/LL-37) gene expression with cardiovascular disease risk factors. Nutr Metab Cardiovasc Dis. 2009;19(10):720–728.
  • Ayub A, Mackness M, Arrol S, et al. Serum paraoxonase after myocardial infarction. ATVB. 1999;19(2):330–335.
  • Shih D, Gu L, Xia Y, et al. Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis. Nature. 1998;394(6690):284–287.
  • Mackness M, Harty D, Bhatnagar D, et al. Serum paraoxonase activity in familial hypercholesterolaemia and insulin-dependent diabetes mellitus. Atherosclerosis. 1991;86(2-3):193–199.