circDENND4C, a novel serum marker for epithelial ovarian cancer, acts as a tumor suppressor by downregulating miR-200b/c

References

• Hao X, Jia Q, Yuan J, et al. MicroRNA‑195 suppresses cell proliferation, migration and invasion in epithelial ovarian carcinoma via inhibition of the CDC42/CCND1 pathway. Int J Mol Med. 2020;46(5):1862–1872.
   PubMed Web of Science ®Google Scholar
• Pendlebury A, Hannan NJ, Binder N, et al. The circulating microRNA-200 family in whole blood are potential biomarkers for high-grade serous epithelial ovarian cancer. Biomed Rep. 2017;6(3):319–322.
   PubMedGoogle Scholar
• Zuberi M, Mir R, Das J, et al. Expression of serum miR-200a, miR-200b, and miR-200c as candidate biomarkers in epithelial ovarian cancer and their association with clinicopathological features. Clin Transl Oncol. 2015;17(10):779–787.
   PubMed Web of Science ®Google Scholar
• Coleman RL, Monk BJ, Sood AK, et al. Latest research and treatment of advanced-stage epithelial ovarian cancer. Nat Rev Clin Oncol. 2013;10(4):211–224.
   PubMed Web of Science ®Google Scholar
• Waldmann A, Eisemann N, Katalinic A. Epidemiology of malignant cervical, corpus uteri and ovarian tumours – current data and epidemiological trends. Geburtshilfe Frauenheilkd. 2013;73(2):123–129.
   PubMed Web of Science ®Google Scholar
• Kang WD, Choi HS, Kim SM. Value of serum CA125 levels in patients with high-risk, early stage epithelial ovarian cancer. Gynecol Oncol. 2010;116(1):57–60.
   PubMed Web of Science ®Google Scholar
• Ruggeri G, Bandiera E, Zanotti L, et al. HE4 and epithelial ovarian cancer: comparison and clinical evaluation of two immunoassays and a combination algorithm. Clin Chim Acta. 2011;412(15-16):1447–1453.
   PubMed Web of Science ®Google Scholar
• Zhang C, Zhang B, Yuan B, et al. RNA-seq profiling of circular RNAs in human small cell lung cancer. Epigenomics. 2020;12(8):685–700.
   PubMed Web of Science ®Google Scholar
• Barrett SP, Salzman J. Circular RNAs: analysis, expression and potential functions. Development. 2016;143(11):1838–1847.
   PubMed Web of Science ®Google Scholar
• Jin C, Shi L, Li Z, et al. Circ_0039569 promotes renal cell carcinoma growth and metastasis by regulating miR-34a-5p/CCL22. Am J Transl Res. 2019;11(8):4935–4945.
   PubMed Web of Science ®Google Scholar
• Rong X, Gao W, Yang X, et al. Downregulation of hsa_circ_0007534 restricts the proliferation and invasion of cervical cancer through regulating miR-498/BMI-1 signaling. Life Sci. 2019;235:116785.
   PubMed Web of Science ®Google Scholar
• Memczak S, Jens M, Elefsinioti A, et al. Circular RNAs are a large class of animal RNAs with regulatory potency. Nature. 2013;495(7441):333–338.
   PubMed Web of Science ®Google Scholar
• Li Z, Huang C, Bao C, et al. Exon-intron circular RNAs regulate transcription in the nucleus. Nat Struct Mol Biol. 2015;22(3):256–264.
   PubMed Web of Science ®Google Scholar
• Lei B, Tian Z, Fan W, et al. Circular RNA: a novel biomarker and therapeutic target for human cancers. Int. J. Med. Sci. 2019;16(2):292–301.
   PubMed Web of Science ®Google Scholar
• Ren S, Liu J, Feng Y, et al. Knockdown of circDENND4C inhibits glycolysis, migration and invasion by up-regulating miR-200b/c in breast cancer under hypoxia. J Exp Clin Cancer Res. 2019;38(1):388.
   PubMed Web of Science ®Google Scholar
• Liang G, Liu Z, Tan L, et al. HIF1α-associated circDENND4C promotes proliferation of breast cancer cells in hypoxic environment. Anticancer Res. 2017;37(8):4337–4343.
   PubMed Web of Science ®Google Scholar
• Kan CW, Hahn MA, Gard GB, et al. Elevated levels of circulating microRNA-200 family members correlate with serous epithelial ovarian cancer. BMC Cancer. 2012;12:627.
   PubMed Web of Science ®Google Scholar
• Cao Q, Lu K, Dai S, et al. Clinicopathological and prognostic implications of the miR-200 family in patients with epithelial ovarian cancer. Int J Clin Exp Pathol. 2014;7(5):2392–2401.
   PubMed Web of Science ®Google Scholar
• Pan C, Stevic I, Müller V, et al. Exosomal microRNAs as tumor markers in epithelial ovarian cancer. Mol Oncol. 2018;12(11):1935–1948.
   PubMed Web of Science ®Google Scholar
• Kapetanakis NI, Uzan C, Jimenez-Pailhes AS, et al. Plasma miR-200b in ovarian carcinoma patients: distinct pattern of pre/post-treatment variation compared to CA-125 and potential for prediction of progression-free survival. Oncotarget. 2015;6(34):36815–36824.
   PubMed Web of Science ®Google Scholar
• Meng X, Müller V, Milde-Langosch K, et al. Circulating cell-free miR-373, miR-200a, miR-200b and miR-200c in patients with epithelial ovarian cancer. Adv Exp Med Biol. 2016;924:3–8.
   PubMed Web of Science ®Google Scholar
• Ojha R, Nandani R, Chatterjee N, et al. Emerging role of circular RNAs as potential biomarkers for the diagnosis of human diseases. Adv Exp Med Biol. 2018;1087:141–157.
   PubMed Web of Science ®Google Scholar
• Zhang HD, Jiang LH, Sun DW, et al. CircRNA: a novel type of biomarker for cancer. Breast Cancer. 2018;25(1):1–7.
   PubMed Web of Science ®Google Scholar
• Rustin GJ, Vergote I, Eisenhauer E, et al. Definitions for response and progression in ovarian cancer clinical trials incorporating RECIST 1.1 and CA 125 agreed by the gynecological cancer intergroup (GCIG). Int J Gynecol Cancer. 2011;21(2):419–423.
   PubMed Web of Science ®Google Scholar
• Muhammad N, Bhattacharya S, Steele R, et al. Anti-miR-203 suppresses ER-positive breast cancer growth and stemness by targeting SOCS3. Oncotarget. 2016;7(36):58595–58605.
   PubMedGoogle Scholar
• Wang Z, Liu W, Wang C, et al. miR-873-5p inhibits cell migration and invasion of papillary thyroid cancer via regulation of CXCL16. Onco Targets Ther. 2020;13:1037–1046.
   PubMed Web of Science ®Google Scholar
• Wang AQ, Lv M, Xu YH, et al. MiR-200b-5p inhibits proliferation of ovarian cancer cells by targeting ATAD2 and regulating PI3K/AKT signaling pathway. Eur Rev Med Pharmacol Sci. 2020;24(19):9860–9868.
   PubMed Web of Science ®Google Scholar
• Savolainen K, Scaravilli M, Ilvesmäki A, et al. Expression of the miR-200 family in tumor tissue, plasma and urine of epithelial ovarian cancer patients in comparison to benign counterparts. BMC Res Notes. 2020;13(1):311.
   PubMed Web of Science ®Google Scholar
• Anastasiadou E, Messina E, Sanavia T, et al. Calcineurin gamma catalytic subunit PPP3CC inhibition by miR-200c-3p affects apoptosis in epithelial ovarian cancer. Genes. 2021;12(9):1400.
   PubMed Web of Science ®Google Scholar
• Guan W, Cui H, Huang P, et al. miR-200b/200a/429 cluster stimulates ovarian cancer development by targeting ING5. J Oncol. 2020;2020:3404059. 20203404059.
   PubMed Web of Science ®Google Scholar