Advanced search
Publication Cover
Annals of Medicine Volume 55, 2023 - Issue 1
Submit an article Journal homepage
1,832
Views
2
CrossRef citations to date
0
Altmetric
Pediatrics

Clinical value of procalcitonin-to-albumin ratio for identifying sepsis in neonates with pneumonia

Tiewei Lia Zhengzhou Key Laboratory of Children’s Infection and Immunity, Children’s Hospital Affiliated to Zhengzhou University, Henan Children’s Hospital, Zhengzhou Children’s Hospital, Zhengzhou, P.R. China;b The Center of Henan Children’s Neurodevelopmental Engineering Research, Children’s Hospital Affiliated to Zhengzhou University, Henan Children’s Hospital, Zhengzhou Children’s Hospital, Zhengzhou, P.R. ChinaCorrespondence[email protected]
View further author information
,
Xiaojuan Lia Zhengzhou Key Laboratory of Children’s Infection and Immunity, Children’s Hospital Affiliated to Zhengzhou University, Henan Children’s Hospital, Zhengzhou Children’s Hospital, Zhengzhou, P.R. ChinaView further author information
,
Zhiwei Zhua Zhengzhou Key Laboratory of Children’s Infection and Immunity, Children’s Hospital Affiliated to Zhengzhou University, Henan Children’s Hospital, Zhengzhou Children’s Hospital, Zhengzhou, P.R. ChinaView further author information
,
Xinrui Liua Zhengzhou Key Laboratory of Children’s Infection and Immunity, Children’s Hospital Affiliated to Zhengzhou University, Henan Children’s Hospital, Zhengzhou Children’s Hospital, Zhengzhou, P.R. ChinaView further author information
,
Geng Donga Zhengzhou Key Laboratory of Children’s Infection and Immunity, Children’s Hospital Affiliated to Zhengzhou University, Henan Children’s Hospital, Zhengzhou Children’s Hospital, Zhengzhou, P.R. ChinaView further author information
,
Zhe Xua Zhengzhou Key Laboratory of Children’s Infection and Immunity, Children’s Hospital Affiliated to Zhengzhou University, Henan Children’s Hospital, Zhengzhou Children’s Hospital, Zhengzhou, P.R. ChinaView further author information
,
Min Zhanga Zhengzhou Key Laboratory of Children’s Infection and Immunity, Children’s Hospital Affiliated to Zhengzhou University, Henan Children’s Hospital, Zhengzhou Children’s Hospital, Zhengzhou, P.R. ChinaView further author information
,
Ying Zhoua Zhengzhou Key Laboratory of Children’s Infection and Immunity, Children’s Hospital Affiliated to Zhengzhou University, Henan Children’s Hospital, Zhengzhou Children’s Hospital, Zhengzhou, P.R. ChinaView further author information
,
Jianwei Yanga Zhengzhou Key Laboratory of Children’s Infection and Immunity, Children’s Hospital Affiliated to Zhengzhou University, Henan Children’s Hospital, Zhengzhou Children’s Hospital, Zhengzhou, P.R. ChinaView further author information
,
Junmei Yanga Zhengzhou Key Laboratory of Children’s Infection and Immunity, Children’s Hospital Affiliated to Zhengzhou University, Henan Children’s Hospital, Zhengzhou Children’s Hospital, Zhengzhou, P.R. ChinaView further author information
,
Panpan Fanga Zhengzhou Key Laboratory of Children’s Infection and Immunity, Children’s Hospital Affiliated to Zhengzhou University, Henan Children’s Hospital, Zhengzhou Children’s Hospital, Zhengzhou, P.R. ChinaView further author information
&
Xiaoliang Qiaoc Center of Laboratory Medicine, Women & Infants Hospital of Zhengzhou, Zhengzhou, P.R. ChinaCorrespondence[email protected]
View further author information
 show all
Pages 920-925 | Received 15 Apr 2022, Accepted 23 Feb 2023, Published online: 13 Mar 2023

References

  • Nissen MD. Congenital and neonatal pneumonia. Paediatr Respir Rev. 2007;8(3):195–203.
  • Marodi L. Neonatal innate immunity to infectious agents. Infection and Immunity. 2006;74(4):1999–2006.
  • Lawn JE, Cousens S, Zupan J. Lancet neonatal survival steering T, 4 million neonatal deaths: when? Where? Why? Lancet (London, England). 2005;365(9462):891–900.
  • Hooven TA, Polin RA. Pneumonia. Semin Fetal Neonatal Med. 2017;22(4):206–213.
  • Shane AL, Sánchez PJ, Stoll BJ. Neonatal sepsis. Lancet (London, England). 2017;390(10104):1770–1780.
  • Weiss SL, Peters MJ, Alhazzani W, et al. Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Intensive Care Med. 2020;46(S1):10–67.
  • Iroh Tam PY, Bendel CM. Diagnostics for neonatal sepsis: current approaches and future directions. Pediatr Res. 2017;82(4):574–583.
  • Rello J, Valenzuela-Sanchez F, Ruiz-Rodriguez M, et al. Sepsis: a review of advances in management. Adv Ther. 2017;34(11):2393–2411.
  • Uhle F, Lichtenstern C, Brenner T, et al. Pathophysiology of sepsis. Anasthesiol Intensivmed Notfallmed Schmerzther. 2015;50(2):114–122.
  • Saucedo-Moreno EM, Fernandez-Rivera E, Ricardez-Garcia JA. Hypoalbuminemia as a predictor of mortality in abdominal sepsis. Cir Cir. 2020;88(4):481–484.
  • Wischmeyer PE. Nutrition therapy in sepsis. Crit Care Clin. 2018;34(1):107–125.
  • McLaughlin J, Chowdhury N, Djurkovic S, et al. Clinical outcomes and financial impacts of malnutrition in sepsis. Nutr Health. 2020;26(3):175–178.
  • Vijayan AL, Ravindran S, Saikant R, et al. Procalcitonin: a promising diagnostic marker for sepsis and antibiotic therapy. No. J Intensive Care. 2017;5(1):51.
  • Wacker C, Prkno A, Brunkhorst FM, et al. Procalcitonin as a diagnostic marker for sepsis: a systematic review and meta-analysis. No. Lancet Infect Dis. 2013;13(5):426–435.
  • Eckart A, Struja T, Kutz A, et al. Relationship of nutritional status, inflammation, and serum albumin levels during acute illness: a prospective study. Am J Med. 2020;133(6):713–722 e717.
  • Soeters PB, Wolfe RR, Shenkin A. Hypoalbuminemia: pathogenesis and clinical significance. JPEN J Parenter Enteral Nutr. 2019;43(2):181–193.
  • Arnau-Barres I, Guerri-Fernandez R, Luque S, et al. Serum albumin is a strong predictor of sepsis outcome in elderly patients. Eur J Clin Microbiol Infect Dis. 2019;38(4):743–746.
  • Gui Y, Xu Y, Yang P. Predictive value of the platelet-to-albumin ratio (par) on the risk of death at admission in patients suffering from severe fever with thrombocytopenia syndrome. JIR. 2021;ume 14:5647–5652.
  • Chen L, Wu X, Qin H, et al. The pct to albumin ratio predicts mortality in patients with acute kidney injury caused by abdominal infection-evoked sepsis. Front Nutr. 2021;8:584461.
  • Goldstein B, Giroir B, Randolph A. International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatric Critical Care Med. 2005;6(1):2–8.
  • Bosmann M, Ward PA. The inflammatory response in sepsis. Trends Immunol. 2013;34(3):129–136.
  • Camacho-Gonzalez A, Spearman PW, Stoll BJ. Neonatal infectious diseases: evaluation of neonatal sepsis. Pediatr Clin North Am. 2013;60(2):367–389.
  • Lippi G, Sanchis-Gomar F. Procalcitonin in inflammatory bowel disease: drawbacks and opportunities. WJG. 2017;23(47):8283–8290.
  • Mohsen AH, Kamel BA. Predictive values for procalcitonin in the diagnosis of neonatal sepsis. Electron Physician. 2015;7(4):1190–1195.
  • Vouloumanou EK, Plessa E, Karageorgopoulos DE, et al. Serum procalcitonin as a diagnostic marker for neonatal sepsis: a systematic review and meta-analysis. Intensive Care Med. 2011;37(5):747–762.
  • Adib M, Bakhshiani Z, Navaei F, et al. Procalcitonin: a reliable marker for the diagnosis of neonatal sepsis. Iran J Basic Med Sci. 2012;15(2):777–782.
  • Habib A, Raza S, Ali U, et al. Diagnostic accuracy of serum procalcitonin (pct) as an early biomarker of neonatal sepsis using blood culture as gold standard. J Coll Physicians Surg Pak. 2021;30(4):383–387.
  • Wang S, Chen D. The correlation between procalcitonin, c-reactive protein and severity scores in patients with sepsis and their value in assessment of prognosis. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2015;27(2):97–101.
  • Don BR, Kaysen G. Serum albumin: relationship to inflammation and nutrition. Semin Dial. 2004;17(6):432–437.
  • Qian SY, Liu J. Relationship between serum albumin level and prognosis in children with sepsis, severe sepsis or septic shock. Zhonghua Er Ke Za Zhi. 2012;50(3):184–187.
  • Yang C, Liu Z, Tian M, et al. Relationship between serum albumin levels and infections in newborn late preterm infants. Med Sci Monit. 2016;22:92–98.
  • Deng S, Gao J, Zhao Z, et al. Albumin/procalcitonin ratio is a sensitive early marker of nosocomial blood stream infection in patients with intra-cerebral hemorrhage. Surgical Infections. 2019;20(8):643–649.
  • Luo X, Yang X, Li J, et al. The procalcitonin/albumin ratio as an early diagnostic predictor in discriminating urosepsis from patients with febrile urinary tract infection. Medicine. 2018;97(28):e11078.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.