Close association of PFASs exposure with hepatic fibrosis than steatosis: evidences from NHANES 2017–2018

References

• Cheng W, Li M, Zhang L, et al. New roles of N6-methyladenosine methylation system regulating the occurrence of non-alcoholic fatty liver disease with N6-methyladenosine-modified MYC. Front Pharmacol. 2022;13:1.
   Web of Science ®Google Scholar
• Liu J, Tian Y, Fu X, et al. Estimating global prevalence, incidence, and outcomes of non-alcoholic fatty liver disease from 2000 to 2021: systematic review and meta-analysis. Chin Med J . 2022;135(14):1682–14.
   PubMed Web of Science ®Google Scholar
• Teng ML, Ng CH, Huang DQ, et al. Global incidence and prevalence of non-alcoholic fatty liver disease. Clin Mol Hepatol. 2023;29(Suppl):S32–S42.
   PubMedGoogle Scholar
• Schaider LA, Balan SA, Blum A, et al. Fluorinated compounds in U.S. Fast food packaging. Environ Sci Technol Lett. 2017;4(3):105–111.
   PubMed Web of Science ®Google Scholar
• Sinclair E, Kim SK, Akinleye HB, et al. Quantitation of gas-phase perfluoroalkyl surfactants and fluorotelomer alcohols released from nonstick cookware and microwave popcorn bags. Environ Sci Technol. 2007;41(4):1180–1185.
   PubMed Web of Science ®Google Scholar
• Hill PJ, Taylor M, Goswami P, et al. Substitution of PFAS chemistry in outdoor apparel and the impact on repellency performance. Chemosphere. 2017;181:500–507.
   PubMed Web of Science ®Google Scholar
• Podder A, Sadmani A, Reinhart D, et al. Per and poly-fluoroalkyl substances (PFAS) as a contaminant of emerging concern in surface water: a transboundary review of their occurrences and toxicity effects. J Hazard Mater. 2021;419:126361.
   PubMed Web of Science ®Google Scholar
• Houde M, De Silva AO, Muir DC, et al. Monitoring of perfluorinated compounds in aquatic biota: an updated review. Environ Sci Technol. 2011;45(19):7962–7973.
   PubMed Web of Science ®Google Scholar
• Calafat AM, Wong LY, Kuklenyik Z, et al. Polyfluoroalkyl chemicals in the U.S. population: data from the national health and nutrition examination survey (NHANES) 2003–2004 and comparisons with NHANES 1999–2000. Environ Health Perspect. 2007;115(11):1596–1602.
   PubMed Web of Science ®Google Scholar
• Jain RB, Ducatman A. Selective associations of recent low concentrations of perfluoroalkyl substances with liver function biomarkers: NHANES 2011 to 2014 data on US adults aged ≥20 years. J Occup Environ Med. 2019;61(4):293–302.
   PubMed Web of Science ®Google Scholar
• Bassler J, Ducatman A, Elliott M, et al. Environmental perfluoroalkyl acid exposures are associated with liver disease characterized by apoptosis and altered serum adipocytokines. Environ Pollut. 2019;247:1055–1063.
   PubMed Web of Science ®Google Scholar
• Qazi MR, Abedi MR, Nelson BD, et al. Dietary exposure to perfluorooctanoate or perfluorooctane sulfonate induces hypertrophy in centrilobular hepatocytes and alters the hepatic immune status in mice. Int Immunopharmacol. 2010;10(11):1420–1427.
   PubMed Web of Science ®Google Scholar
• Behr AC, Plinsch C, Braeuning A, et al. Activation of human nuclear receptors by perfluoroalkylated substances (PFAS). Toxicol in Vitro. 2020;62:104700.
   PubMed Web of Science ®Google Scholar
• Li X, Wang Z, Klaunig JE. The effects of perfluorooctanoate on high fat diet induced non-alcoholic fatty liver disease in mice. Toxicology. 2019;416:1–14.
   PubMed Web of Science ®Google Scholar
• Huck I, Beggs K, Apte U. Paradoxical protective effect of perfluorooctanesulfonic acid against high-fat diet-induced hepatic steatosis in mice. Int J Toxicol. Sep/Oct2018;37(5):383–392.
   PubMed Web of Science ®Google Scholar
• Chalasani N, Younossi Z, Lavine JE, et al. The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American gastroenterological association, American association for the study of liver diseases, and American college of gastroenterology. Gastroenterology. 2012;142(7):1592–1609.
   PubMed Web of Science ®Google Scholar
• Younossi ZM, Paik JM, Al Shabeeb R, et al. Are there outcome differences between NAFLD and metabolic-associated fatty liver disease? Hepatology. 2022;76(5):1423–1437.
   PubMed Web of Science ®Google Scholar
• Castera L, Friedrich-Rust M, Loomba R. Noninvasive assessment of liver disease in patients with nonalcoholic fatty liver disease. Gastroenterology. 2019;156(5):1264–1281.e4.
   PubMed Web of Science ®Google Scholar
• Barr RG, Ferraioli G, Palmeri ML, et al. Elastography assessment of liver fibrosis: society of radiologists in ultrasound consensus conference statement. Radiology. 2015;276(3):845–861.
   PubMed Web of Science ®Google Scholar
• Siddiqui MS, Vuppalanchi R, Van Natta ML, et al. Vibration-controlled transient elastography to assess fibrosis and steatosis in patients with nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol. 2019;17(1):156–163.e2.
   PubMed Web of Science ®Google Scholar
• Zhang X, Heredia NI, Balakrishnan M, et al. Prevalence and factors associated with NAFLD detected by vibration controlled transient elastography among US adults: results from NHANES 2017-2018. PLOS One. 2021;16(6):e0252164.
   PubMed Web of Science ®Google Scholar
• Liu J, Tan L, Liu Z, et al. The association between non-alcoholic fatty liver disease (NAFLD) and advanced fibrosis with blood selenium level based on the NHANES 2017-2018. Ann Med. 2022;54(1):2259–2268.
   PubMed Web of Science ®Google Scholar
• Heredia NI, Zhang X, Balakrishnan M, et al. Physical activity and diet quality in relation to non-alcoholic fatty liver disease: a cross-sectional study in a representative sample of U.S. adults using NHANES 2017–2018. Prev Med. 2022;154:106903.
   PubMed Web of Science ®Google Scholar
• Brosset E, Ngueta G. Exposure to per- and polyfluoroalkyl substances and glycemic control in older US adults with type 2 diabetes mellitus. Environ Res. 2023;216(Pt 3):114697.
   PubMedGoogle Scholar
• Bedogni G, Bellentani S, Miglioli L, et al. The fatty liver index: a simple and accurate predictor of hepatic steatosis in the general population. BMC Gastroenterol. 2006;6(1):33.
   PubMed Web of Science ®Google Scholar
• Kotronen A, Peltonen M, Hakkarainen A, et al. Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors. Gastroenterology. 2009;137(3):865–872.
   PubMed Web of Science ®Google Scholar
• Long MT, Pedley A, Colantonio LD, et al. Development and validation of the framingham steatosis index to identify persons with hepatic steatosis. Clin Gastroenterol Hepatol. 2016;14(8):1172–1180.e2.
   PubMed Web of Science ®Google Scholar
• Sterling RK, Lissen E, Clumeck N, et al. Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection. Hepatology. 2006;43(6):1317–1325.
   PubMed Web of Science ®Google Scholar
• EASL clinical practice guidelines on non-invasive tests for evaluation of liver disease severity and prognosis – 2021 update. J Hepatol. 2021;75(3):659–689.
   PubMed Web of Science ®Google Scholar
• Anstee QM, Castera L, Loomba R. Impact of non-invasive biomarkers on hepatology practice: past, present and future. J Hepatol. 2022;76(6):1362–1378.
   PubMed Web of Science ®Google Scholar
• Angulo P, Hui JM, Marchesini G, et al. The NAFLD fibrosis score: a noninvasive system that identifies liver fibrosis in patients with NAFLD. Hepatology. 2007;45(4):846–854.
   PubMed Web of Science ®Google Scholar
• Ampuero J, Pais R, Aller R, et al. Development and validation of hepamet fibrosis scoring system-A simple, noninvasive test to identify patients with nonalcoholic fatty liver disease with advanced fibrosis. Clin Gastroenterol Hepatol. 2020;18(1):216–225.e5.
   PubMed Web of Science ®Google Scholar
• Paluch AE, Bajpai S, Ballin M, et al. Prospective ­association of daily steps with cardiovascular disease: a harmonized meta-analysis. Circulation. 2023;147(2):122–131.
   PubMed Web of Science ®Google Scholar
• Bobb JF, Claus Henn B, Valeri L, et al. Statistical software for analyzing the health effects of multiple concurrent exposures via Bayesian kernel machine regression. Environ Health. 2018;17(1):67.
   PubMedGoogle Scholar
• Kim SS, Meeker JD, Keil AP, et al. Exposure to 17 trace metals in pregnancy and associations with urinary oxidative stress biomarkers. Environ Res. 2019;179(Pt B):108854.
   PubMedGoogle Scholar
• Spinella R, Sawhney R, Jalan R. Albumin in chronic liver disease: structure, functions and therapeutic implications. Hepatol Int. 2016;10(1):124–132.
   PubMed Web of Science ®Google Scholar
• Samuel VT, Shulman GI. Nonalcoholic fatty liver disease as a nexus of metabolic and hepatic diseases. Cell Metab. 2018;27(1):22–41.
   PubMed Web of Science ®Google Scholar
• Murata S, Maruyama T, Nowatari T, et al. Signal transduction of platelet-induced liver regeneration and ­decrease of liver fibrosis. Int J Mol Sci. 2014;15(4):5412–5425.
   PubMed Web of Science ®Google Scholar
• Rosen MB, Das KP, Rooney J, et al. PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling. Toxicology. 2017;387:95–107.
   PubMed Web of Science ®Google Scholar
• Fan Y, Li X, Xu Q, et al. Serum albumin mediates the effect of multiple per- and polyfluoroalkyl substances on serum lipid levels. Environ Pollut. 2020;266(Pt 2):115138.
   PubMedGoogle Scholar
• Gao K, Zhuang T, Liu X, et al. Prenatal exposure to per- and polyfluoroalkyl substances (PFASs) and association between the placental transfer efficiencies and dissociation constant of serum proteins-PFAS complexes. Environ Sci Technol. 2019;53(11):6529–6538.
   PubMed Web of Science ®Google Scholar
• Schillemans T, Iszatt N, Remy S, et al. Cross-sectional associations between exposure to per- and polyfluoroalkyl substances and body mass index among European teenagers in the HBM4EU aligned studies. Environ Pollut. 2023;316(Pt 1):120566.
   PubMedGoogle Scholar
• Wang J, Zhang Y, Zhang W, et al. Association of perfluorooctanoic acid with HDL cholesterol and circulating miR-26b and miR-199-3p in workers of a fluorochemical plant and nearby residents. Environ Sci Technol. 2012;46(17):9274–9281.
   PubMed Web of Science ®Google Scholar
• Liu D, Xiao Y, Evans BS, et al. Negative feedback regulation of fatty acid production based on a malonyl-CoA sensor-actuator. ACS Synth Biol. 2015;4(2):132–140.
   PubMed Web of Science ®Google Scholar
• Darrow LA, Groth AC, Winquist A, et al. Modeled perfluorooctanoic acid (PFOA) exposure and liver function in a mid-Ohio valley community. Environ Health Perspect. 2016;124(8):1227–1233.
   PubMed Web of Science ®Google Scholar
• Gallo V, Leonardi G, Genser B, et al. Serum perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) concentrations and liver function biomarkers in a population with elevated PFOA exposure. Environ Health Perspect.2012;120(5):655–660.
   PubMed Web of Science ®Google Scholar
• Borghese MM, Liang CL, Owen J, et al. Individual and mixture associations of perfluoroalkyl substances on liver function biomarkers in the Canadian health measures survey. Environ Health. 2022;21(1):85.
   PubMed Web of Science ®Google Scholar
• Zare Jeddi M, Dalla Zuanna T, Barbieri G, et al. Associations of perfluoroalkyl substances with prevalence of metabolic syndrome in highly exposed young adult community residents-A cross-sectional study in Veneto region, Italy. IJERPH. 2021;18(3):1194.
   Web of Science ®Google Scholar
• Lin CY, Wang C, Sung FC, et al. Association between serum per- and polyfluoroalkyl substances and thrombograms in young and middle-aged Taiwanese populations. Ecotoxicol Environ Saf. 2022;236:113457.
   PubMed Web of Science ®Google Scholar
• Freberg BI, Haug LS, Olsen R, et al. Occupational exposure to airborne perfluorinated compounds during professional ski waxing. Environ Sci Technol. 2010;44(19):7723–7728.
   PubMed Web of Science ®Google Scholar
• Jin C, Sun Y, Islam A, et al. Perfluoroalkyl acids including perfluorooctane sulfonate and perfluorohexane sulfonate in firefighters. J Occup Environ Med. 2011;53(3):324–328.
   PubMed Web of Science ®Google Scholar
• EPA. Proposed PFAS National Primary Drinking Water Regulation. United States Environmental Protection Agency. Accessed April 20, 2023. https://www.epa.gov/sdwa/and-polyfluoroalkyl-substances-pfas.
   Google Scholar
• NIOSH. Per- and polyfluoroalkyl substances (PFAS). The National Institute for Occupational Safety and Health. Accessed April 20, 2023. https://www.cdc.gov/niosh/topics/pfas/default.html.
   Google Scholar