1,888
Views
0
CrossRef citations to date
0
Altmetric
Pregnancy, Childbirth & Women's Health

The effect of circulating adiponectin levels on incident gestational diabetes mellitus: systematic review and meta‑analysis

, , , , , , , & show all
Article: 2224046 | Received 03 Jan 2023, Accepted 06 Jun 2023, Published online: 15 Jun 2023

References

  • Magliano DJ, Boyko EJ; IDF Diabetes Atlas 10th edition scientific committee. IDF DIABETES ATLAS [Internet]. 10th edition. Brussels: International Diabetes Federation; 2021.
  • Ye W, Luo C, Huang J, et al. Gestational diabetes mellitus and adverse pregnancy outcomes: systematic review and meta-analysis. BMJ. 2022;377:1. doi: 10.1136/bmj-2021-067946.
  • Kramer CK, Campbell S, Retnakaran R. Gestational diabetes and the risk of cardiovascular disease in women: a systematic review and meta-analysis. Diabetologia. 2019;62(6):905–915. doi: 10.1007/s00125-019-4840-2.
  • Vounzoulaki E, Khunti K, Abner SC, et al. Progression to type 2 diabetes in women with a known history of gestational diabetes: systematic review and meta-analysis. BMJ. 2020;369:m1361. doi: 10.1136/bmj.m1361.
  • Chodick G, Tenne Y, Barer Y, et al. Gestational diabetes and long-term risk for dyslipidemia: a population-based historical cohort study. BMJ Open Diabetes Res Care. 2020;8(1):e000870. doi: 10.1136/bmjdrc-2019-000870.
  • Pathirana MM, Lassi ZS, Ali A, et al. Association between metabolic syndrome and gestational diabetes mellitus in women and their children: a systematic review and meta-analysis. Endocrine. 2021;71(2):310–320. doi: 10.1007/s12020-020-02492-1.
  • Lowe WLJr, Scholtens DM, Kuang A, et al. Hyperglycemia and adverse pregnancy outcome follow-up study (HAPO FUS): maternal gestational diabetes mellitus and childhood glucose metabolism. Diabetes Care. 2019;42(3):372–380. doi: 10.2337/dc18-1646.
  • Rowland J, Wilson CA. The association between gestational diabetes and ASD and ADHD: a systematic review and meta-analysis. Sci Rep. 2021;11(1):5136. doi: 10.1038/s41598-021-84573-3.
  • Buchanan TA, Xiang AH. Gestational diabetes mellitus. J Clin Invest. 2005;115(3):485–491. doi: 10.1172/JCI24531.
  • Fasshauer M, Blüher M, Stumvoll M. Adipokines in gestational diabetes. Lancet Diabetes Endocrinol. 2014;2(6):488–499. doi: 10.1016/S2213-8587(13)70176-1.
  • Zavalza-Gómez AB, Anaya-Prado R, Rincón-Sánchez AR, et al. Adipokines and insulin resistance during pregnancy. Diabetes Res Clin Pract. 2008;80(1):8–15. doi: 10.1016/j.diabres.2007.12.012.
  • Li S, Shin HJ, Ding EL, et al. Adiponectin levels and risk of type 2 diabetes: a systematic review and meta-analysis. JAMA. 2009;302(2):179–188. doi: 10.1001/jama.2009.976.
  • Iliodromiti S, Sassarini J, Kelsey TW, et al. Accuracy of circulating adiponectin for predicting gestational diabetes: a systematic review and meta-analysis. Diabetologia. 2016;59(4):692–699. doi: 10.1007/s00125-015-3855-6.
  • Schuitemaker JHN, Beernink RHJ, Franx A, et al. First trimester secreted Frizzled-related protein 4 and other adipokine serum concentrations in women developing gestational diabetes mellitus. PLOS One. 2020;15(11):e0242423. doi: 10.1371/journal.pone.0242423.
  • Ye Y, Wu P, Wang Y, et al. Adiponectin, leptin, and leptin/adiponectin ratio with risk of gestational diabetes mellitus: a prospective nested case-control study among Chinese women. Diabetes Res Clin Pract. 2022;191:110039. doi: 10.1016/j.diabres.2022.110039.
  • Florian AR, Cruciat G, Pop RM, et al. Predictive role of altered leptin, adiponectin and 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid secretion in gestational diabetes mellitus. Exp Ther Med. 2021;21(5):520. doi: 10.3892/etm.2021.9951.
  • Al-Musharaf S, Sabico S, Hussain SD, et al. Inflammatory and adipokine status from early to midpregnancy in Arab women and its associations with gestational diabetes mellitus. Dis Markers. 2021;2021:8862494. doi: 10.1155/2021/8862494.
  • Stroup DF, Berlin JA, Morton SC, et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis of observational studies in epidemiology (MOOSE) group. JAMA. 2000;283(15):2008–2012. doi: 10.1001/jama.283.15.2008.
  • Wells G, Shea B, O’connell D, et al. The Newcastle–Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. [cited 2022 Nov]. Available at: http://www.ohri.ca/programs/clinical_epidemiology/oxford.htm
  • Roshanzamir F, Miraghajani M, Rouhani MH, et al. The association between circulating fetuin-A levels and type 2 diabetes mellitus risk: systematic review and meta-analysis of observational studies. J Endocrinol Invest. 2018;41(1):33–47. doi: 10.1007/s40618-017-0697-8.
  • Luo D, Wan X, Liu J, et al. Optimally estimating the sample mean from the sample size, median, mid-range, and/or mid-quartile range. Stat Methods Med Res. 2018;27(6):1785–1805. doi: 10.1177/0962280216669183.
  • Wan X, Wang W, Liu J, et al. Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range. BMC Med Res Methodol. 2014;14:135. doi: 10.1186/1471-2288-14-135.
  • DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986;7(3):177–188. doi: 10.1016/0197-2456(86)90046-2.
  • Higgins JP, Thompson SG, Deeks JJ, et al. Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557–560. doi: 10.1136/bmj.327.7414.557.
  • Blettner M, Sauerbrei W, Schlehofer B, et al. Traditional reviews, meta-analyses and pooled analyses in epidemiology. Int J Epidemiol. 1999;28(1):1–9. doi: 10.1093/ije/28.1.1.
  • Abell SK, Shorakae S, Boyle JA, et al. Role of serum biomarkers to optimise a validated clinical risk prediction tool for gestational diabetes. Aust N Z J Obstet Gynaecol. 2019;59(2):251–257. doi: 10.1111/ajo.12833.
  • Correa PJ, Venegas P, Palmeiro Y, et al. First trimester prediction of gestational diabetes mellitus using plasma biomarkers: a case-control study. J Perinat Med. 2019;47(2):161–168. doi: 10.1515/jpm-2018-0120.
  • Coussa A, Hasan HA, Barber TM. Early predictors of gestational diabetes mellitus in IVF-Conceived pregnancies. Endocr Pract. 2021;27(6):579–585. doi: 10.1016/j.eprac.2020.10.020.
  • Sir-Petermann T, Echiburú B, Maliqueo MM, et al. Serum adiponectin and lipid concentrations in pregnant women with polycystic ovary syndrome. Hum Reprod. 2007;22(7):1830–1836. doi: 10.1093/humrep/dem090.
  • Xiao L, Zhao JP, Nuyt AM, et al. Female fetus is associated with greater maternal insulin resistance in pregnancy. Diabet Med. 2014;31(12):1696–1701. doi: 10.1111/dme.12562.
  • Yang X, Ye Y, Wang Y, et al. Association between early-pregnancy serum C-peptide and risk of gestational diabetes mellitus: a nested case-control study among Chinese women. Nutr Metab. 2022;19(1):56. doi: 10.1186/s12986-022-00691-3.
  • Abell SK, Shorakae S, Harrison CL, et al. The association between dysregulated adipocytokines in early pregnancy and development of gestational diabetes. Diabetes Metab Res Rev. 2017;33(8). doi: 10.1002/dmrr.2926.
  • Corcoran SM, Achamallah N, Loughlin JO, et al. First trimester serum biomarkers to predict gestational diabetes in a high-risk cohort: striving for clinically useful thresholds. Eur J Obstet Gynecol Reprod Biol. 2018;222:7–12. doi: 10.1016/j.ejogrb.2017.12.051.
  • Ferreira AF, Rezende JC, Vaikousi E, et al. Maternal serum visfatin at 11–13 weeks of gestation in gestational diabetes mellitus. Clin Chem. 2011;57(4):609–613. doi: 10.1373/clinchem.2010.159806.
  • Francis EC, Li M, Hinkle SN, et al. Adipokines in early and mid-pregnancy and subsequent risk of gestational diabetes: a longitudinal study in a multiracial cohort. BMJ Open Diab Res Care. 2020;8(1):e001333. doi: 10.1136/bmjdrc-2020-001333.
  • Gao XL, Yang HX, Zhao Y. Variations of tumor necrosis factor-alpha, leptin and adiponectin in mid-trimester of gestational diabetes mellitus. Chin Med J (Engl). 2008;121(8):701–705.
  • Georgiou HM, Lappas M, Georgiou GM, et al. Screening for biomarkers predictive of gestational diabetes mellitus. Acta Diabetol. 2008;45(3):157–165. doi: 10.1007/s00592-008-0037-8.
  • Ianniello F, Quagliozzi L, Caruso A, et al. Low adiponectin in overweight/obese women: association with diabetes during pregnancy. Eur Rev Med Pharmacol Sci. 2013;17(23):3197–3205.
  • Lacroix M, Battista MC, Doyon M, et al. Lower adiponectin levels at first trimester of pregnancy are associated with increased insulin resistance and higher risk of developing gestational diabetes mellitus. Diabetes Care. 2013;36(6):1577–1583. doi: 10.2337/dc12-1731.
  • Lain KY, Daftary AR, Ness RB, et al. First trimester adipocytokine concentrations and risk of developing gestational diabetes later in pregnancy. Clin Endocrinol (Oxf). 2008;69(3):407–411. doi: 10.1111/j.1365-2265.2008.03198.x.
  • Lee SM, Kwak SH, Koo JN, et al. Non-alcoholic fatty liver disease in the first trimester and subsequent development of gestational diabetes mellitus. Diabetologia. 2019;62(2):238–248. doi: 10.1007/s00125-018-4779-8.
  • Lomakova YD, Chen X, Stein TP, et al. Decreased adiponectin levels in early pregnancy are associated with high risk of prematurity for African American women. J Clin Med. 2022;11(11):3213. doi: 10.3390/jcm11113213.
  • Madhu SV, Bhardwaj S, Jhamb R, et al. Prediction of gestational diabetes from first trimester serum adiponectin levels in Indian women. Indian J Endocrinol Metab. 2019;23(5):536–539. doi: 10.4103/ijem.IJEM_319_19.
  • Maitland RA, Seed PT, Briley AL, et al. Prediction of gestational diabetes in obese pregnant women from the UK pregnancies better eating and activity (UPBEAT) pilot trial. Diabet Med. 2014;31(8):963–970. doi: 10.1111/dme.12482.
  • Nanda S, Savvidou M, Syngelaki A, et al. Prediction of gestational diabetes mellitus by maternal factors and biomarkers at 11 to 13 weeks. Prenat Diagn. 2011;31(2):135–141. doi: 10.1002/pd.2636.
  • Paradisi G, Ianniello F, Tomei C, et al. Longitudinal changes of adiponectin, carbohydrate and lipid metabolism in pregnant women at high risk for gestational diabetes. Gynecol Endocrinol. 2010;26(7):539–545. doi: 10.3109/09513591003632084.
  • Ramachandrayya SA, D’Cunha P, Rebeiro C. Maternal circulating levels of adipocytokines and insulin resistance as predictors of gestational diabetes mellitus: preliminary findings of a longitudinal descriptive study. J Diabetes Metab Disord. 2020;19(2):1447–1452. doi: 10.1007/s40200-020-00672-4.
  • Ravnsborg T, Andersen LL, Trabjerg ND, et al. First-trimester multimarker prediction of gestational diabetes mellitus using targeted mass spectrometry. Diabetologia. 2016;59(5):970–979. doi: 10.1007/s00125-016-3869-8.
  • Savvidou M, Nelson SM, Makgoba M, et al. First-trimester prediction of gestational diabetes mellitus: examining the potential of combining maternal characteristics and laboratory measures. Diabetes. 2010;59(12):3017–3022. doi: 10.2337/db10-0688.
  • Sweeting AN, Wong J, Appelblom H, et al. A novel early pregnancy risk prediction model for gestational diabetes mellitus. Fetal Diagn Ther. 2019;45(2):76–84. doi: 10.1159/000486853.
  • Thagaard IN, Krebs L, Holm JC, et al. Adiponectin and leptin as first trimester markers for gestational diabetes mellitus: a cohort study. Clin Chem Lab Med. 2017;55(11):1805–1812. doi: 10.1515/cclm-2017-0427.
  • White SL, Lawlor DA, Briley AL, et al. Early antenatal prediction of gestational diabetes in obese women: development of prediction tools for targeted intervention. PLOS One. 2016;11(12):e0167846. doi: 10.1371/journal.pone.0167846.
  • Williams MA, Qiu C, Muy-Rivera M, et al. Plasma adiponectin concentrations in early pregnancy and subsequent risk of gestational diabetes mellitus. J Clin Endocrinol Metab. 2004;89(5):2306–2311. doi: 10.1210/jc.2003-031201.
  • Yuan XS, Shi H, Wang HY, et al. Ficolin-3/adiponectin ratio for the prediction of gestational diabetes mellitus in pregnant women. J Diabetes Investig. 2018;9(2):403–410. doi: 10.1111/jdi.12688.
  • Zhu Y, Hedderson MM, Quesenberry CP, et al. Central obesity increases the risk of gestational diabetes partially through increasing insulin resistance. Obesity. 2019;27(1):152–160. doi: 10.1002/oby.22339.
  • Bao W, Baecker A, Song Y, et al. Adipokine levels during the first or early second trimester of pregnancy and subsequent risk of gestational diabetes mellitus: a systematic review. Metabolism. 2015;64(6):756–764. doi: 10.1016/j.metabol.2015.01.013.
  • Xu J, Zhao YH, Chen YP, et al. Maternal circulating concentrations of tumor necrosis factor-alpha, leptin, and adiponectin in gestational diabetes mellitus: a systematic review and meta-analysis. ScientificWorldJournal. 2014;2014:926932. doi: 10.1155/2014/926932.
  • Hedderson MM, Darbinian J, Havel PJ, et al. Low prepregnancy adiponectin concentrations are associated with a marked increase in risk for development of gestational diabetes mellitus. Diabetes Care. 2013;36(12):3930–3937. doi: 10.2337/dc13-0389.
  • Fuglsang J, Skjaerbaek C, Frystyk J, et al. A longitudinal study of serum adiponectin during normal pregnancy. BJOG. 2006;113(1):110–113. doi: 10.1111/j.1471-0528.2005.00792.x.
  • Retnakaran R, Qi Y, Connelly PW, et al. Low adiponectin concentration during pregnancy predicts postpartum insulin resistance, beta cell dysfunction and fasting glycaemia. Diabetologia. 2010;53(2):268–276. doi: 10.1007/s00125-009-1600-8.
  • Thomann R, Rossinelli N, Keller U, et al. Differences in low-grade chronic inflammation and insulin resistance in women with previous gestational diabetes mellitus and women with polycystic ovary syndrome. Gynecol Endocrinol. 2008;24(4):199–206. doi: 10.1080/09513590801893398.
  • Sirico A, Rossi ED, Degennaro VA, et al. Placental diabesity: placental VEGF and CD31 expression according to pregestational BMI and gestational weight gain in women with gestational diabetes. Arch Gynecol Obstet. 2023;307(6):1823–1831. doi: 10.1007/s00404-022-06673-3.
  • Sirico A, Dell’Aquila M, Tartaglione L, et al. PTH-rP and PTH-R1 expression in placentas from pregnancies complicated by gestational diabetes: new insights into the pathophysiology of hyperglycemia in pregnancy. Diagnostics (Basel). 2021;11(8):1356. doi: 10.3390/diagnostics11081356.
  • Mousa A, Abell SK, Shorakae S, et al. Relationship between vitamin D and gestational diabetes in overweight or obese pregnant women may be mediated by adiponectin.Mol Nutr Food Res. 2017;61(11). doi: 10.1002/mnfr.201700488.
  • Mir MM, Mir R, Alghamdi MAA, et al. Differential association of selected adipocytokines, adiponectin, leptin, resistin, visfatin and chemerin, with the pathogenesis and progression of type 2 diabetes mellitus (T2DM) in the Asir region of Saudi Arabia: a case control study. J Pers Med. 2022;12(5):735. doi: 10.3390/jpm12050735.
  • Cnop M, Havel PJ, Utzschneider KM, et al. Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex. Diabetologia. 2003;46(4):459–469. doi: 10.1007/s00125-003-1074-z.
  • Huang LT, Wu SL, Liao X, et al. Adiponectin gene polymorphisms and risk of gestational diabetes mellitus: a meta-analysis. World J Clin Cases. 2019;7(5):572–584. doi: 10.12998/wjcc.v7.i5.572.
  • Gong X, You L, Li F, et al. The association of adiponectin with risk of pre-diabetes and diabetes in different subgroups: cluster analysis of a general population in South China. Endocr Connect. 2021;10(11):1410–1419. doi: 10.1530/EC-21-0235.
  • Vecchiola A, García K, González-Gómez LM, et al. Plasminogen activator inhibitor-1 and adiponectin are associated with metabolic syndrome components. Am J Hypertens. 2022;35(4):311–318. doi: 10.1093/ajh/hpab138.
  • Orrù S, Nigro E, Mandola A, et al. A functional interplay between IGF-1 and adiponectin. Int J Mol Sci. 2017;18(10):2145. doi: 10.3390/ijms18102145.
  • Frankenberg ADV, Reis AF, Gerchman F. Relationships between adiponectin levels, the metabolic syndrome, and type 2 diabetes: a literature review. Arch Endocrinol Metab. 2017;61(6):614–622. doi: 10.1590/2359-3997000000316.
  • Xu A, Wang Y, Keshaw H, et al. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest. 2003;112(1):91–100. doi: 10.1172/JCI17797.
  • Wang Q, Du J, Liu F. Changes of serum adiponectin and glycated albumin levels in gestational diabetes mellitus patients and their relationship with insulin resistance. Iran J Public Health. 2020;49(7):1252–1261. doi: 10.18502/ijph.v49i7.3578.
  • Havel PJ. Control of energy homeostasis and insulin action by adipocyte hormones: leptin, acylation stimulating protein, and adiponectin. Curr Opin Lipidol. 2002;13(1):51–59. doi: 10.1097/00041433-200202000-00008.
  • Mallardo M, Ferraro S, Daniele A, et al. GDM-complicated pregnancies: focus on adipokines. Mol Biol Rep. 2021;48(12):8171–8180. doi: 10.1007/s11033-021-06785-0.