Increased blood pressure variability is associated with probable rapid eye movement sleep behaviour disorder in elderly hypertensive patients

References

• Stevens SL, Wood S, Koshiaris C, et al. Blood pressure variability and cardiovascular disease: systematic review and meta-analysis. BMJ. 2016;354:i4098.
   PubMed Web of Science ®Google Scholar
• Chowdhury EK, Owen A, Krum H, Second Australian National Blood Pressure Study Management Committee, et al. Systolic blood pressure variability is an important predictor of cardiovascular outcomes in elderly hypertensive patients. J Hypertens. 2014;32(3):525–533.
   PubMed Web of Science ®Google Scholar
• Sarafidis PA, Ruilope LM, Loutradis C, et al. Blood pressure variability increases with advancing chronic kidney disease stage: a cross-sectional analysis of 16 546 hypertensive patients. J Hypertens. 2018;36(5):1076–1085.
   PubMed Web of Science ®Google Scholar
• Chau NP, Bauduceau B, Chanudet X, et al. Ambulatory blood pressure in diabetic subjects. Am J Hypertens. 1994;7(6):487–491.
   PubMed Web of Science ®Google Scholar
• Scuteri A, Rovella V, Alunni Fegatelli D, et al. An operational definition of SHATS (systemic hemodynamic atherosclerotic syndrome): role of arterial stiffness and blood pressure variability in elderly hypertensive subjects. Int J Cardiol. 2018;263:132–137.
   PubMed Web of Science ®Google Scholar
• Tadic M, Cuspidi C, Pencic B, et al. The interaction between blood pressure variability, obesity, and left ventricular mechanics: findings from the hypertensive population. J Hypertens. 2016;34(4):772–780.
   PubMed Web of Science ®Google Scholar
• Zhu Y, Chen X, Geng S, et al. Association between ambulatory blood pressure variability and frailty among older hypertensive patients. J Clin Hypertens (Greenwich). 2020;22(9):1703–1712.
   PubMed Web of Science ®Google Scholar
• Liu Q, Han L, Chang F, et al. The relationship between the autonomic nervous function and early renal dysfunction in elderly patients with mild-to-moderate essential hypertension. Clin Exp Hypertens (New York, NY: 1993). 2018;40(2):136–140.
   PubMed Web of Science ®Google Scholar
• Van Ryswyk E, Mukherjee S, Chai-Coetzer CL, et al. Sleep disorders, including sleep apnea and hypertension. Am J Hypertens. 2018;31(8):857–864.
   PubMed Web of Science ®Google Scholar
• Hoshide S, Kario K, Chia YC, et al. Characteristics of hypertension in obstructive sleep apnea: an Asian experience. J Clin Hypertens (Greenwich). 2021;23(3):489–495.
   PubMed Web of Science ®Google Scholar
• Jarrin DC, Alvaro PK, Bouchard MA, et al. Insomnia and hypertension: a systematic review. Sleep Med Rev. 2018;41:3–38.
   PubMed Web of Science ®Google Scholar
• Lo K, Woo B, Wong M, et al. Subjective sleep quality, blood pressure, and hypertension: a meta-analysis. J Clin Hypertens. 2018;20(3):592–605.
   PubMed Web of Science ®Google Scholar
• Van Den Eeden SK, Albers KB, Davidson JE, et al. Risk of cardiovascular disease associated with a restless legs syndrome diagnosis in a retrospective cohort study from Kaiser Permanente Northern California. Sleep. 2015;38(7):1009–1015.
   PubMed Web of Science ®Google Scholar
• Kim JS, Park HE, Oh YS, et al. Orthostatic hypotension and cardiac sympathetic denervation in Parkinson disease patients with REM sleep behavioral disorder. J Neurol Sci. 2016;362:59–63.
   PubMed Web of Science ®Google Scholar
• Mansukhani MP, Covassin N, Somers VK. Neurological sleep disorders and blood pressure: current evidence. Hypertension. 2019;74(4):726–732.
   PubMed Web of Science ®Google Scholar
• Schenck CH, Bundlie SR, Ettinger MG, et al. Chronic behavioral disorders of human REM sleep: a new category of parasomnia. Sleep. 1986;9(2):293–308.
   PubMed Web of Science ®Google Scholar
• Howell MJ, Schenck CH. Rapid eye movement sleep behavior disorder and neurodegenerative disease. JAMA Neurol. 2015;72(6):707–712.
   PubMed Web of Science ®Google Scholar
• Palma JA, Kaufmann H. Orthostatic hypotension in Parkinson disease. Clin Geriatr Med. 2020;36(1):53–67.
   PubMed Web of Science ®Google Scholar
• Loew F, Gauthey L, Koerffy A, et al. Postprandial hypotension and orthostatic blood pressure responses in elderly Parkinson's disease patients. J Hypertens. 1995;13(11):1291–1297.
   PubMed Web of Science ®Google Scholar
• Rocchi C, Placidi F, Liguori C, et al. Daytime autonomic activity in idiopathic rapid eye movement sleep behavior disorder: a preliminary study. Sleep Med. 2018;52:163–167.
   PubMed Web of Science ®Google Scholar
• Tamura Y, Ishikawa J, Fujiwara Y, et al. Prevalence of frailty, cognitive impairment, and sarcopenia in outpatients with cardiometabolic disease in a frailty clinic. BMC Geriatr. 2018;18(1):264.
   PubMedGoogle Scholar
• Stiasny-Kolster K, Mayer G, Schäfer S, et al. The REM sleep behavior disorder screening questionnaire–a new diagnostic instrument. Mov Disord. 2007;22(16):2386–2393.
   PubMed Web of Science ®Google Scholar
• Miyamoto T, Miyamoto M, Iwanami M, et al. The REM sleep behavior disorder screening questionnaire: validation study of a Japanese version. Sleep Med. 2009;10(10):1151–1154.
   PubMed Web of Science ®Google Scholar
• Li K, Li SH, Su W, et al. Diagnostic accuracy of REM sleep behaviour disorder screening questionnaire: a meta-analysis. Neurol Sci: Off J Italian Neurol Soc Italian Soc Neurol Sci. 2017;38(6):1039–1046.
   PubMed Web of Science ®Google Scholar
• Postuma RB, Montplaisir J, Lanfranchi P, et al. Cardiac autonomic denervation in Parkinson's disease is linked to REM sleep behavior disorder. Mov Disord. 2011;26(8):1529–1533.
   PubMed Web of Science ®Google Scholar
• Ferini-Strambi L, Oldani A, Zucconi M, et al. Cardiac autonomic activity during wakefulness and sleep in REM sleep behavior disorder. Sleep. 1996;19(5):367–369.
   PubMed Web of Science ®Google Scholar
• Goldstein DS. Orthostatic hypotension as an early finding in Parkinson's disease. Clin Auton Res. 2006;16(1):46–54.
   PubMed Web of Science ®Google Scholar
• Milazzo V, Di Stefano C, Vallelonga F, et al. Reverse blood pressure dipping as marker of dysautonomia in Parkinson disease. Parkinsonism Relat Disord. 2018;56:82–87.
   PubMed Web of Science ®Google Scholar
• Chen SW, Wang YK, Dou RH, et al. Characteristics of the 24-h ambulatory blood pressure monitoring in patients with Parkinson's disease – the SFC BP multicentre study in China. J Hypertens. 2020;38(11):2270–2278.
   PubMed Web of Science ®Google Scholar
• Vallelonga F, Di Stefano C, Merola A, et al. Blood pressure circadian rhythm alterations in alpha-synucleinopathies. J Neurol. 2019;266(5):1141–1152.
   PubMed Web of Science ®Google Scholar
• Oka H, Umehara T, Nakahara A, et al. Comparisons of cardiovascular dysautonomia and cognitive impairment between de novo Parkinson's disease and de novo dementia with *lewy bodies. BMC Neurol. 2020;20(1):350.
   PubMed Web of Science ®Google Scholar
• Jain S, Goldstein DS. Cardiovascular dysautonomia in Parkinson disease: from pathophysiology to pathogenesis. Neurobiol Dis. 2012;46(3):572–580.
   PubMed Web of Science ®Google Scholar
• Braak H, Del Tredici K, Rüb U, et al. Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol Aging. 2003;24(2):197–211.
   PubMed Web of Science ®Google Scholar
• Kaufmann H, Nahm K, Purohit D, et al. Autonomic failure as the initial presentation of Parkinson disease and dementia with Lewy bodies. Neurology. 2004;63(6):1093–1095.
   PubMed Web of Science ®Google Scholar
• Plaschke M, Trenkwalder P, Dahlheim H, et al. Twenty-four-hour blood pressure profile and blood pressure responses to head-up tilt tests in Parkinson's disease and multiple system atrophy. J Hypertens. 1998;16(10):1433–1441.
   PubMed Web of Science ®Google Scholar
• Bilo G, Parati G. Blood pressure variability and kidney disease: another vicious circle? J Hypertens. 2018;36(5):1019–1021.
   PubMed Web of Science ®Google Scholar
• Sakakura K, Ishikawa J, Okuno M, et al. Exaggerated ambulatory blood pressure variability is associated with cognitive dysfunction in the very elderly and quality of life in the younger elderly. Am J Hypertens. 2007;20(7):720–727.
   PubMed Web of Science ®Google Scholar
• Rouch L, Cestac P, Sallerin B, for the SAGES Investigators, et al. Visit-to-visit blood pressure variability is associated with cognitive decline and incident dementia: the SAGES cohort. Hypertension (1979). 2020;76(4):1280–1288.
   PubMed Web of Science ®Google Scholar
• Iranzo A, Fernández-Arcos A, Tolosa E, et al. Neurodegenerative disorder risk in idiopathic REM sleep behavior disorder: study in 174 patients. PLoS One. 2014;9(2):e89741.
   PubMed Web of Science ®Google Scholar
• Postuma RB, Iranzo A, Hu M, et al. Risk and predictors of dementia and *parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study. Brain. 2019;142(3):744–759.
   PubMed Web of Science ®Google Scholar
• Chahine LM, Daley J, Horn S, et al. Questionnaire-based diagnosis of REM sleep behavior disorder in Parkinson's disease. Mov Disord. 2013;28(8):1146–1149.
   PubMed Web of Science ®Google Scholar