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Research Articles

Urine sodium excretion is related to extracellular water volume but not to blood pressure in 510 normotensive and never-treated hypertensive subjects

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Article: 2170869 | Received 19 Oct 2022, Accepted 17 Jan 2023, Published online: 28 Jan 2023

References

  • Williams B, Mancia G, Spiering W, et al. 2018 ESC/ESH guidelines for the management of arterial hypertension. Eur Heart J. 2018;39(33):3021–3104.
  • Vasan RS, Larson MG, Leip EP, et al. Impact of high-normal blood pressure on the risk of cardiovascular disease. N Engl J Med. 2001;345(18):1291–1297.
  • Kshirsagar AV, Carpenter M, Bang H, et al. Blood pressure usually considered normal is associated with an elevated risk of cardiovascular disease. Am J Med. 2006;119(2):133–141.
  • Verma N, Rastogi S, Chia Y-C, et al. Non-pharmacological management of hypertension. J Clin Hypertens. 2021;23(7):1275–1283.
  • Filippini T, Malavolti M, Whelton PK, et al. Blood pressure effects of sodium reduction: dose-response meta-analysis of experimental studies. Circulation. 2021;143(16):1542–1567.
  • Drewnowski A, Rehm CD, Maillot M, et al. The feasibility of meeting the WHO guidelines for sodium and potassium: a cross-national comparison study. BMJ Open. 2015;5(3):e006625.
  • World Health Organization. Salt reduction; 2020. Available from: www.who.int/news-room/fact-sheets/detail/salt-reduction
  • Bie P. Mechanisms of sodium balance: total body sodium, surrogate variables, and renal sodium excretion. Am J Physiol Regul Integr Comp Physiol. 2018;315(5):R945–R962.
  • Mente A, O'Donnell M, Rangarajan S, et al. Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies. Lancet. 2016;388(10043):465–475.
  • Mente A, O'Donnell M, Rangarajan S, et al. Urinary sodium excretion, blood pressure, cardiovascular disease, and mortality: a community-level prospective epidemiological cohort study. Lancet. 2018;392(10146):496–506.
  • Thomas MC, Moran J, Forsblom C, et al. The association between dietary sodium intake, ESRD, and all-cause mortality in patients with type 1 diabetes. Diabetes Care. 2011;34(4):861–866.
  • Li J, Zhen Z, Huang P, et al. Salt restriction and risk of adverse outcomes in heart failure with preserved ejection fraction. Heart. 2022;108(17):1377–1382.
  • Alonso S, Tan M, Wang C, et al. Impact of the 2003 to 2018 population salt intake reduction program in England. Hypertension. 2021;77(4):1086–1094.
  • Lerchl K, Rakova N, Dahlmann A, et al. Agreement between 24-hour salt ingestion and sodium excretion in a controlled environment. Hypertension. 2015;66(4):850–857.
  • Rossitto G, Mary S, Chen JY, et al. Tissue sodium excess is not hypertonic and reflects extracellular volume expansion. Nat Commun. 2020;11(1):4222.
  • Minegishi S, Luft FC, Titze J, et al. Sodium handling and interaction in numerous organs. Am J Hypertens. 2020;33(8):687–694.
  • Selvarajah V, Mäki-Petäjä KM, Pedro L, et al. Novel mechanism for buffering dietary salt in humans: effects of salt loading on skin sodium, vascular endothelial growth factor C, and blood pressure. Hypertension. 2017;70(5):930–937.
  • Tahvanainen A, Koskela J, Tikkakoski A, et al. Analysis of cardiovascular responses to passive head‐up tilt using continuous pulse wave analysis and impedance cardiography. Scand J Clin Lab Invest. 2009;69(1):128–137.
  • Tikkakoski AJ, Tahvanainen AM, Leskinen MH, et al. Hemodynamic alterations in hypertensive patients at rest and during passive head-up tilt. J Hypertens. 2013;31(5):906–915.
  • Choudhary MK, Värri E, Matikainen N, et al. Primary aldosteronism: higher volume load, cardiac output and arterial stiffness than in essential hypertension. J Intern Med. 2021;289(1):29–41.
  • Katz A, Nambi SS, Mather K, et al. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab. 2000;85(7):2402–2410.
  • Inker LA, Schmid CH, Tighiouart H, et al. Estimating glomerular filtration rate from serum creatinine and cystatin C. N Engl J Med. 2012;367(1):20–29.
  • Juutilainen A, Savolainen K, Romppanen J, et al. Combination of LC–MS/MS aldosterone and automated direct renin in screening for primary aldosteronism. Clin Chim Acta. 2014;433:209–215.
  • Turpeinen U, Hämäläinen E, Stenman U-H. Determination of aldosterone in serum by liquid chromatography–tandem mass spectrometry. J Chromatogr B. 2008;862(1-2):113–118.
  • Choudhary MK, Eräranta A, Tikkakoski AJ, et al. Effect of present versus previous smoking on non-invasive haemodynamics. Sci Rep. 2018;8(1):13643.
  • Kangas P, Tahvanainen A, Tikkakoski A, et al. Increased cardiac workload in the upright posture in men: noninvasive hemodynamics in men versus women. J Am Heart Assoc. 2016;5:e002883.
  • Chen C-H, Nevo E, Fetics B, et al. Estimation of central aortic pressure waveform by mathematical transformation of radial tonometry pressure: validation of generalized transfer function. Circulation. 1997;95(7):1827–1836.
  • Kööbi T, Kähönen M, Koskinen M, et al. Comparison of bioimpedance and radioisotope methods in the estimation of extracellular water volume before and after coronary artery bypass grafting operation. Clin Physiol. 2000;20(4):283–291.
  • Kööbi T, Kähönen M, Iivainen T, et al. Simultaneous non-invasive assessment of arterial stiffness and haemodynamics–a validation study. Clin Physiol Funct Imaging. 2003;23(1):31–36.
  • Kööbi T, Kaukinen S, Ahola T, et al. Non-invasive measurement of cardiac output: whole-body impedance cardiography in simultaneous comparison with thermodilution and direct oxygen Fick methods. Intensive Care Med. 1997;23(11):1132–1137.
  • Tishchenko M. (Estimation of the stroke volume by integral rheogram of the human body) [in Russian]. Sechenov Physiol J. 1973;59:1216–1224.
  • Nadler SB, Hidalgo JH, Bloch T. Prediction of blood volume in normal human adults. Surgery. 1962;51(2):224–232.
  • Albert SN. Blood volume and extracellular fluid volume (American Lecture Series, Publication no. 807). 2nd ed. Springfield (IL): Thomas CC; 1971.
  • Dubois F, Dubois E. A formula to estimate the approximate surface area if height and weight be known. Arch Intern Med. 1916;17:863–871.
  • Laurent S, Cockcroft J, Van Bortel L, et al. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur Heart J. 2006;27(21):2588–2605.
  • Townsend RR, Wilkinson IB, Schiffrin EL, et al. Recommendations for improving and standardizing vascular research on arterial stiffness: a scientific statement from the American Heart Association. Hypertension. 2015;66(3):698–722.
  • Funder JW, Carey RM, Mantero F, et al. The management of primary aldosteronism: case detection, diagnosis, and treatment: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2016;101(5):1889–1916.
  • Kesteloot H, Joossens JV. Relationship of serum sodium, potassium, calcium, and phosphorus with blood pressure. Belgian interuniversity research on nutrition and health. Hypertension. 1988;12(6):589–593.
  • Baldo MP, Brant LCC, Cunha RS, et al. The association between salt intake and arterial stiffness is influenced by a sex-specific mediating effect through blood pressure in normotensive adults: the ELSA-Brasil study. J Clin Hypertens. 2019;21(12):1771–1779.
  • Graudal NA, Hubeck-Graudal T, Jurgens G. Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride. Cochrane Database Syst Rev. 2020;12(12):CD004022.
  • Pimenta E, Gaddam KK, Oparil S, et al. Effects of dietary sodium reduction on blood pressure in subjects with resistant hypertension: results from a randomized trial. Hypertension. 2009;54(3):475–481.
  • Ma Y, He FJ, Sun Q, et al. 24-hour urinary sodium and potassium excretion and cardiovascular risk. N Engl J Med. 2022;386(3):252–263.
  • Campbell KL, Johnson DW, Bauer JD, et al. A randomized trial of sodium-restriction on kidney function, fluid volume and adipokines in CKD patients. BMC Nephrol. 2014;15:57.
  • Feng W, Dell’Italia LJ, Sanders PW. Novel paradigms of salt and hypertension. J Am Soc Nephrol. 2017;28(5):1362–1369.
  • Jablonski KL, Racine ML, Geolfos CJ, et al. Dietary sodium restriction reverses vascular endothelial dysfunction in middle-aged/older adults with moderately elevated systolic blood pressure. J Am Coll Cardiol. 2013;61(3):335–343.
  • Selvaraj S, Djoussé L, Aguilar FG, et al. Association of estimated sodium intake with adverse cardiac structure and function: from the HyperGEN study. J Am Coll Cardiol. 2017;70(6):715–724.
  • Razavi MA, Bazzano LA, Nierenberg J, et al. Advances in genomics research of blood pressure responses to dietary sodium and potassium intakes. Hypertension. 2021;78(1):4–15.
  • Park CY, Jo G, Lee J, et al. Association between dietary sodium intake and disease burden and mortality in Koreans between 1998 and 2016: the Korea National Health and Nutrition Examination Survey. Nutr Res Pract. 2020;14(5):501–518.
  • Terry AL, Cogswell ME, Wang C-Y, et al. Feasibility of collecting 24-h urine to monitor sodium intake in the National Health and Nutrition Examination Survey. Am J Clin Nutr. 2016;104(2):480–488.
  • Svensén CH, Waldrop KS, Edsberg L, et al. Natriuresis and the extracellular volume expansion by hypertonic saline. J Surg Res. 2003;113(1):6–12.
  • Yoshikawa M, Torimoto K, Hirayama A, et al. Daily salt intake is associated with leg edema and nocturnal urinary volume in elderly men. Neurourol Urodyn. 2020;39(5):1550–1556.
  • Titze J, Maillet A, Lang R, et al. Long-term sodium balance in humans in a terrestrial space station simulation study. Am J Kidney Dis. 2002;40(3):508–516.
  • Machnik A, Neuhofer W, Jantsch J, et al. Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C–dependent buffering mechanism. Nat Med. 2009;15(5):545–552.
  • Ruskoaho H. Cardiac hormones as diagnostic tools in heart failure. Endocr Rev. 2003;24(3):341–356.
  • Volpe M, Rubattu S, Burnett J. Natriuretic peptides in cardiovascular diseases: current use and perspectives. Eur Heart J. 2014;35(7):419–425.