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Brief Report

Depression and loneliness may have a direct connection without mediating factors

ORCID Icon, , , , , & show all
Pages 553-557 | Received 17 Nov 2020, Accepted 18 Feb 2021, Published online: 15 Mar 2021

References

  • Perlman D, Peplau LA. Toward a social psychology of loneliness. In: Duck S, Gilmour R, editors. Personal relationships: personal relationships in disorder. London: Academic Press; 1981:31–56.
  • Weiss RS. 1974. Loneliness: the experience of emotional and social isolation. Cambridge, MA: MIT Press.
  • Shankar A, McMunn A, Banks J, et al. Loneliness, social isolation, and behavioral and biological health indicators in older adults. Health Psychol. 2011;30(4):377–385.
  • Hawkley L, Cacioppo J. Loneliness matters: a theoretical and empirical review of consequences and mechanisms. Ann Behav Med. 2010;40(2):218–227.
  • Algren MH, Ekholm O, Nielsen L, et al. Social isolation, loneliness, socioeconomic status, and health-risk behaviour in deprived neighbourhoods in Denmark: a cross-sectional study. SSM Popul Health. 2020;10:100546.
  • Luanaigh CÓ, Lawlor BA. Loneliness and the health of older people. Int J Geriatr Psychiatry. 2008;23(12):1213–1221.
  • Cacioppo JT, Hawkley LC, Thisted RA. Perceived social isolation makes me sad: 5-year cross-lagged analyses of loneliness and depressive symptomatology in the Chicago Health, Aging, and Social Relations Study. Psychol Aging. 2010;25(2):453–463.
  • Domènech-Abella J, Mundó J, Haro JM, et al. Anxiety, depression, loneliness and social network in the elderly: longitudinal associations from The Irish Longitudinal Study on Ageing (TILDA). J Affect Disord. 2019;246:82–88.
  • McHugh Power J, Hannigan C, Hyland P, et al. Depressive symptoms predict increased social and emotional loneliness in older adults. Aging Ment. Health. 2020;24(1):110–118.
  • Solmi M, Veronese N, Galvano D, et al. Factors associated with loneliness: an umbrella review of observational studies. J. Affect Disord. 2020;271:131–138.
  • Richard A, Rohrmann S, Vandeleur CL, et al. Loneliness is adversely associated with physical and mental health and lifestyle factors: results from a Swiss national survey. PLoS One. 2017;12(7):e0181442.
  • Schrempft S, Jackowska M, Hamer M, et al. Associations between social isolation, loneliness, and objective physical activity in older men and women. BMC Public Health. 2019;19(1):74.
  • Tolmunen T, Laukkanen JA, Hintikka J, et al. Low maximal oxygen uptake is associated with elevated depressive symptoms in middle-aged men. Eur J Epidemiol. 2006;21(9):701–706.
  • Kraav S, Awoyemi O, Junttila N, et al. The effects of loneliness and social isolation on all-cause, injury, cancer, and CVD mortality in a cohort of middle-aged Finnish men. A prospective study. Aging Mental Health. 2020. DOI: 10.1080/13607863.2020.1830945
  • Salonen JT, Nyyssonen K, Korpela H, et al. High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men. Circulation. 1992;86(3):803–811.
  • Ihanainen M, Salonen R, Salonen JT, et al. Nutrition data collection in the Kuopio ischaemic heart disease risk factor study: nutrient intake of middle-aged eastern Finnish men. Nutr Res. 1989;9(6):597–604.
  • Lakka TA, Kauhanen J, Salonen JT. Conditioning leisure time physical activity and cardiorespiratory fitness in sociodemographic groups of middle-ages men in eastern Finland. Int J Epidemiol. 1996;25(1):86–93.
  • Lynch JW, Kaplan GA, Shema SJ. Cumulative impact of sustained economic hardship on physical, cognitive, psychological, and social functioning. N Engl J Med. 1997;337(26):1889–1895.
  • Ravona-Springer R, Lutski M, Schnaider Beeri M, et al. C-reactive protein in midlife is associated with depressive symptoms two decades later among men with coronary heart disease. Nord J Psychiatry. 2020;74(3):226–228.
  • Lakka HM, Laaksonen DE, Lakka TA, et al. The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA. 2002;288(21):2709–2716.
  • Luojus MK, Lehto SM, Tolmunen T, et al. Sleep duration and incidence of lung cancer in ageing men. BMC Public Health. 2014;14(1):295.
  • Tertsunen HM, Hantunen S, Tuomainen TP, et al. Healthy Nordic diet and risk of disease death among men: the Kuopio Ischaemic Heart Disease Risk Factor Study. Eur J Nutr. 2020;59(8): 3545–3553.
  • Stickley A, Koyanagi A, Koposov R, et al. Loneliness and health risk behaviours among Russian and U.S. adolescents: a cross-sectional study. BMC Public Health. 2014;14:366
  • Wootton RE, Greenstone HSR, Abdellaoui A, et al. Bidirectional effects between loneliness, smoking and alcohol use: evidence from a Mendelian randomization study. Addiction. 2021;116(2):400–406.
  • Gordon AM, Del Rosario K, Flores AJ, et al. Bidirectional links between social rejection and sleep. Psychosomatic Med. 2019;81:739–748.
  • Moieni M, Eisenberger NI. Effects of inflammation on social processes and implications for health. Ann NY Acad Sci. 2018;1428(1):5–13.
  • Cacioppo JT, Hawkley LC, Crawford LE, et al. Loneliness and health: potential mechanisms. Psychosom Med. 2002;64(3):407–417.
  • Hegeman A, Schutter N, Comijs H, et al. Loneliness and cardiovascular disease and the role of late-life depression. Int J Geriatr Psychiatry. 2018;33(1):e65–e72.
  • Hayes AF. 2018. Introduction to mediation, moderation, and conditional process analysis: a regression-based approach. Second edition. New York: Guilford Press.
  • Dahlberg L, Agahi N, Lennartsson C. Lonelier than ever? Loneliness of older people over two decades. Arch Gerontol Geriatr. 2018;75:96–103.
  • Park NS, Jang Y, Lee BS, et al. The relation between living alone and depressive symptoms in older Korean Americans: do feelings of loneliness mediate? Aging Ment Health. 2017;21(3):304–312.
  • Zhao X, Zhang D, Wu M, et al. Loneliness and depression symptoms among the elderly in nursing homes: a moderated mediation model of resilience and social support. Psychiatry Res. 2018;268:143–151.
  • Ypsilanti A, Lazuras L, Powell P, et al. Self-disgust as a potential mechanism explaining the association between loneliness and depression. J Affect Disord. 2019;243:108–115.