Clinical testing of mild traumatic brain injury using computerised eye-tracking tests

References

• Feng V. Mild traumatic brain injury burden in New Zealand: a population-based incidence and short term outcomes study. University of Auckland; 2014. [ accessed 25 Aug 2021]. https://researchspace.auckland.ac.nz/bitstream/handle/2292/25007/whole.pdf?sequence=6&isAllowed=y.
   Google Scholar
• Lozano D, Gonzales-Portillo GS, Acosta S et al. Neuroinflammatory responses to traumatic brain injury: etiology, clinical consequences, and therapeutic opportunities. Neuropsychiatr Dis Treat 2015; 11: 97–106.
   PubMed Web of Science ®Google Scholar
• Mena JH, Sanchez AI, Rubiano AM et al. Effect of the modified Glasgow Coma Scale score criteria for mild traumatic brain injury on mortality prediction: comparing classic and modified Glasgow Coma Scale score model scores of 13. J Trauma 2011; 71: 1185–1192. discussion 1193.
   PubMedGoogle Scholar
• McCrea M. American academy of clinical neuropsychology. Mild traumatic brain injury and postconcussion syndrome : the new evidence base for diagnosis and treatment. Oxford University Press; 2008. [ accessed 17 July 2018]. https://books.google.co.nz/books?hl=en&lr=&id=Y0M9LOL40EMC&oi=fnd&pg=PR5&dq=traumatic+brain+injury+McCrea,+2008&ots=O03Gf5CHA_&sig=uIRjkYC7e3agy5Rb7afdqc0HTG0#v=onepage&q=traumaticbraininjuryMcCrea%2C2008&f=false.
   Google Scholar
• Legarreta AD, Mummareddy N, Yengo-Kahn AM et al. On-field assessment of concussion: clinical utility of the King-Devick test. Open Access J Sport Med 2019; 10: 115–121.
   PubMed Web of Science ®Google Scholar
• Dhawan PS, Leong D, Tapsell L et al. King-Devick test identifies real-time concussion and asymptomatic concussion in youth athletes. Neurol Clin Pract 2017; 7: 464.
   PubMedGoogle Scholar
• Higgins KL, Denney RL, Maerlender A. Sandbagging on the Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) in a high school athlete population. Arch Clin Neuropsychol 2017; 32: 259–266.
   PubMed Web of Science ®Google Scholar
• Kapoor N, Ciuffreda KJ. Vision disturbances following traumatic brain injury. Curr Treat Options Neurol. 2002; 4: 271–280.
   PubMedGoogle Scholar
• Ciuffreda KJ, Ludlam D, Thiagarajan P. Oculomotor diagnostic protocol for the mTBI population. Optom - J Am Optom Assoc 2011; 82: 61–63.
   PubMedGoogle Scholar
• Ciuffreda KJ, Ludlam DP, Yadav NK et al. Traumatic brain injury visual consequences, diagnosis, and treatment. Adv Ophthalmol Optom 2016; 1: 307–333.
   Google Scholar
• Treleaven Takasaki. Characteristics of visual disturbances reported by subjects with neck pain. Man Ther 2014; 19: 203–207.
   PubMed Web of Science ®Google Scholar
• Diwakar M, Harrington DL, Maruta J et al. Filling in the gaps: anticipatory control of eye movements in chronic mild traumatic brain injury. NeuroImage Clin. 2015; 8: 210–223.
   PubMed Web of Science ®Google Scholar
• Lencer R, Trillenberg P. Neurophysiology and neuroanatomy of smooth pursuit in humans. Brain Cogn 2008; 68: 219–228.
   PubMed Web of Science ®Google Scholar
• Purves D, Augustine G, Fitzpatrick D et al. Central vestibular pathways: eye, head, and body reflexes. 2nd ed. Massachusettes: Sinauer Associates Sunderland; 2001 [ accessed 4 Sept 2018]. https://www.ncbi.nlm.nih.gov/books/NBK10987/.
   Google Scholar
• Troost BT. The neurology of eye movements. 5th ed. New York: Oxford University Press. Epub ahead of print 1984. doi:10.1212/wnl.34.6.845-c
   Google Scholar
• Feigin VL, Theadom A, Barker-Collo S et al. Incidence of traumatic brain injury in New Zealand: a population-based study. Lancet Neurol 2013; 12: 53–64.
   PubMed Web of Science ®Google Scholar
• Hillier SL, Hiller JE, Metzer J. Epidemiology of traumatic brain injury in South Australia. Brain Inj 1997; 11: 649–659.
   PubMed Web of Science ®Google Scholar
• Fessler DMT, Tiokhin LB, Holbrook C et al. Foundations of the crazy bastard hypothesis: nonviolent physical risk-taking enhances conceptualized formidability. Evol Hum Behav. 2014; 35: 26–33.
   Web of Science ®Google Scholar
• Iverson GL, Lange RT, Franzen MD. Effects of mild traumatic brain injury cannot be differentiated from substance abuse. Brain Inj 2005; 19: 11–18.
   PubMed Web of Science ®Google Scholar
• Te Ao B, Brown P, Tobias M et al. Cost of traumatic brain injury in New Zealand: evidence from a population-based study. Neurology 2014; 83: 1645–1652.
   PubMed Web of Science ®Google Scholar
• Mani R, Asper L, Khuu SK. Deficits in saccades and smooth-pursuit eye movements in adults with traumatic brain injury: a systematic review and meta-analysis. Brain Inj. 2018;32:1–22.
   PubMed Web of Science ®Google Scholar
• Ventura RE, Balcer LJ, Galetta SL et al. Ocular motor assessment in concussion: current status and future directions. J Neurol Sci 2016; 361: 79–86.
   PubMed Web of Science ®Google Scholar
• Hoffer ME, Balaban C, Szczupak M et al. The use of oculomotor, vestibular, and reaction time tests to assess mild traumatic brain injury (mTBI) over time. Laryngoscope Investig Otolaryngol. 2017; 2: 157–165.
   PubMed Web of Science ®Google Scholar
• Ruff RM, Camenzuli L, Mueller J. Miserable minority: emotional risk factors that influence the outcome of a mild traumatic brain injury. Brain Inj 1996; 10: 551–566.
   PubMed Web of Science ®Google Scholar
• Iverson GL. Outcome from mild traumatic brain injury. Curr Opin Psychiatry 2005; 18: 301–317.
   PubMed Web of Science ®Google Scholar
• Rohling ML, Larrabee GJ, Millis SR. The “miserable minority” following mild traumatic brain injury: who are they and do meta-analyses hide them? Clin Neuropsychol 2012; 26: 197–213.
   PubMed Web of Science ®Google Scholar
• Ciuffreda KJ, Joshi NR, Truong JQ. Understanding the effects of mild traumatic brain injury on the pupillary light reflex. Concussion. 2017;2:CNC36.
   PubMedGoogle Scholar
• Chen JW, Vakil-Gilani K, Williamson KL et al. Infrared pupillometry, the neurological pupil index and unilateral pupillary dilation after traumatic brain injury: implications for treatment paradigms. J Korean Phys Soc 2014; 3: 1–10.
   Google Scholar
• Turnbull PRK, Irani N, Lim N et al. Origins of pupillary hippus in the autonomic nervous system. Investig Ophthalmol Vis Sci 2017; 58: 197–203.
   PubMed Web of Science ®Google Scholar
• Pillai C, Gittinger JW. Vision testing in the evaluation of concussion. Semin Ophthalmol 2017; 32: 144–152.
   PubMed Web of Science ®Google Scholar
• Thomas G, Urosevich JEC-A, Capó-Aponte J et al. Pupillary light reflex as an objective biomarker for early identification of blast-induced mTBI. J Spine Epub ahead of print 2013. doi:10.4172/2165-7939.S4-004.
   Google Scholar
• Thiagarajan P, Ciuffreda KJ. Pupillary responses to light in chronic non-blast-induced mTBI. Brain Inj 2015; 29: 1420–1425.
   PubMed Web of Science ®Google Scholar
• Truong JQ, Ciuffreda KJ. Objective pupillary correlates of photosensitivity in the normal and mild traumatic brain injury populations. Mil Med 2016; 181: 1382–1390.
   PubMed Web of Science ®Google Scholar
• Verriotto JD, Gonzalez A, Aguilar MC et al. New methods for quantification of visual photosensitivity threshold and symptoms. Transl Vis Sci Technol 2017; 6: 18.
   PubMed Web of Science ®Google Scholar
• McDowell JE, Dyckman KA, Austin BP et al. Neurophysiology and neuroanatomy of reflexive and volitional saccades: evidence from studies of humans. Brain Cogn 2008; 68: 255–270.
   PubMed Web of Science ®Google Scholar
• Cifu DX, Wares JR, Hoke KW et al. Differential eye movements in mild traumatic brain injury versus normal controls. J Head Trauma Rehabil 2015; 30. doi:10.1097/HTR.0000000000000036.
   PubMed Web of Science ®Google Scholar
• DiCesare CA, Kiefer AW, Nalepka P et al. Quantification and analysis of saccadic and smooth pursuit eye movements and fixations to detect oculomotor deficits. Behav Res Methods 2017; 49: 258–266.
   PubMed Web of Science ®Google Scholar
• Drew AS, Langan J, Halterman C et al. Attentional disengagement dysfunction following mTBI assessed with the gap saccade task. Neurosci Lett 2007; 417: 61–65.
   PubMed Web of Science ®Google Scholar
• Kapoor N, Ciuffreda KJ, Han Y. Oculomotor rehabilitation in acquired brain injury: a case series. Arch Phys Med Rehabil 2004; 85: 1667–1678.
   PubMed Web of Science ®Google Scholar
• Ting WKC, Schweizer TA, Topolovec-Vranic J et al. Antisaccadic eye movements are correlated with corpus callosum white matter mean diffusivity, stroop performance, and symptom burden in mild traumatic brain injury and concussion. Front Neurol 2016; 6: 271.
   PubMed Web of Science ®Google Scholar
• Matsuda T, Matsuura M, Ohkubo T et al. Functional MRI mapping of brain activation during visually guided saccades and antisaccades: cortical and subcortical networks. Psychiatry Res - Neuroimaging 2004; 131: 147–155.
   PubMed Web of Science ®Google Scholar
• Clementz BA, Brahmbhatt SB, McDowell JE et al. When does the brain inform the eyes whether and where to move? An EEG study in humans. Cereb Cortex 2007; 17: 2634–2643.
   PubMed Web of Science ®Google Scholar
• Curtis CE, D’Esposito M. Success and failure suppressing reflexive behavior. J Cogn Neurosci 2003; 15: 409–418.
   PubMed Web of Science ®Google Scholar
• DeHaan A, Halterman C, Langan J et al. Cancelling planned actions following mild traumatic brain injury. Neuropsychologia 2007; 45: 406–411.
   PubMed Web of Science ®Google Scholar
• Hunfalvay M, Roberts C-M, Murray N, et al. Horizontal and vertical self-paced saccades as a diagnostic marker of traumatic brain injury. Concussion. Epub ahead of print 25 July 2019;4. doi:10.2217/CNC-2019-0001
   PubMedGoogle Scholar
• Heitger MH, Jones RD, Macleod AD et al. Impaired eye movements in post-concussion syndrome indicate suboptimal brain function beyond the influence of depression, malingering or intellectual ability. Brain 2009; 132: 2850–2870.
   PubMed Web of Science ®Google Scholar
• Johnson B, Zhang K, Hallett M et al. Functional neuroimaging of acute oculomotor deficits in concussed athletes. Brain Imaging Behav 2015; 9: 564–573.
   PubMed Web of Science ®Google Scholar
• Johnson B, Hallett M, Slobounov S. Follow-up evaluation of oculomotor performance with fMRI in the subacute phase of concussion. Neurology 2015; 85: 1163–1166.
   PubMed Web of Science ®Google Scholar
• Mulhall LE, Williams IM, Abel LA. Bedside tests of saccades after head injury. J Neuroophthalmol 1999; 19: 160–165.
   PubMed Web of Science ®Google Scholar
• Taghdiri F, Chung J, Irwin S et al. Decreased number of self-paced saccades in post-concussion syndrome associated with higher symptom burden and reduced white matter integrity. J Neurotrauma 2018; 35: 719–729.
   PubMed Web of Science ®Google Scholar
• Collewijn H, Kowler E. The significance of microsaccades for vision and oculomotor control. J Vis 2008; 8: 20.
   PubMed Web of Science ®Google Scholar
• Brysbaert M, Drieghe D, Vitu F. Word skipping: implications for theories of eye movement control in reading. Cogn Process Eye Guid. 2005;16: 53–77.
   Google Scholar
• Engbert R, Mergenthaler K. Microsaccades are triggered by low retinal image slip. Proc Natl Acad Sci 2006; 103: 7192–7197.
   PubMed Web of Science ®Google Scholar
• Martinez-Conde S, Macknik SL, Troncoso XG et al. Microsaccades counteract visual fading during fixation. Neuron 2006; 49: 297–305.
   PubMed Web of Science ®Google Scholar
• Hunfalvay M, Murray NP, Carrick FR. Fixation stability as a biomarker for differentiating mild traumatic brain injury from age matched controls in pediatrics. Brain Inj 2021; 35: 209–214.
   PubMed Web of Science ®Google Scholar
• Engbert R, Kliegl R. Microsaccades uncover the orientation of covert attention. Vision Res 2003; 43: 1035–1045.
   PubMed Web of Science ®Google Scholar
• Maruta J, Jaw E, Modera P et al. Frequency responses to visual tracking stimuli may be affected by concussion. Mil Med 2017; 182: 120–123.
   PubMed Web of Science ®Google Scholar
• Han Y, Ciuffreda KJ, Kapoor N. Reading-related oculomotor testing and training protocols for acquired brain injury in humans. Brain Res Protoc 2004; 14: 1–12.
   PubMedGoogle Scholar
• Wetzel PA, Lindblad AS, Raizada H et al. Eye tracking results in postconcussive syndrome versus normative participants. Investig Ophthalmol Vis Sci 2018; 59: 4011–4019.
   PubMed Web of Science ®Google Scholar
• Strupp M, Kremmyda O, Adamczyk C et al. Central ocular motor disorders, including gaze palsy and nystagmus. J Neurol 2014; 261: S542–58.
   PubMed Web of Science ®Google Scholar
• Deans P, O’Laughlin L, Brubaker B et al. Use of eye movement tracking in the differential diagnosis of Attention Deficit Hyperactivity Disorder (ADHD) and reading disability. Psychology 2010; 01: 238–246.
   Google Scholar
• Sharpe JA. Neurophysiology and neuroanatomy of smooth pursuit: lesion studies. Brain Cogn 2008; 68: 241–254.
   PubMed Web of Science ®Google Scholar
• Kerzel D, Gegenfurtner KR. Neuronal processing delays are compensated in the sensorimotor branch of the visual system. Curr Biol 2003; 13: 1975–1978.
   PubMed Web of Science ®Google Scholar
• Maruta J, Suh M, Niogi SN et al. Visual tracking synchronization as a metric for concussion screening. J Head Trauma Rehabil Epub ahead of print 2010. doi:10.1097/HTR.0b013e3181e67936.
   PubMed Web of Science ®Google Scholar
• Thiagarajan P, Ciuffreda KJ, Ludlam DP. Vergence dysfunction in mild traumatic brain injury (mTBI): a review. Ophthalmic Physiol Opt 2011; 31: 456–468.
   PubMed Web of Science ®Google Scholar
• Brahm KD, Wilgenburg HM, Kirby J et al. Visual impairment and dysfunction in combat-injured servicemembers with traumatic brain injury. Optom Vis Sci Epub ahead of print 2009. doi:10.1097/OPX.0b013e3181adff2d.
   PubMed Web of Science ®Google Scholar
• Alvarez TL, Kim EH, Vicci VR et al. Concurrent vision dysfunctions in convergence insufficiency with traumatic brain injury. Optom Vis Sci 2012; 89: 1740–1751.
   PubMed Web of Science ®Google Scholar
• Cooper J, Jamal N. Convergence insufficiency-a major review. Optometry (St Louis, Mo) 2012; 83: 137–158.
   PubMedGoogle Scholar
• Ciuffreda KJ, Kapoor N, Rutner D et al. Occurrence of oculomotor dysfunctions in acquired brain injury: a retrospective analysis. Optometry 2007; 78: 155–161.
   PubMedGoogle Scholar
• Alvarez TL, Vicci VR, Alkan Y, et al. Vision therapy in adults with convergence insufficiency: clinical and functional magnetic resonance imaging measures. Optom Vis Sci. 2010;87:985-1002.
   Google Scholar
• Cohen M, Groswasser Z, Barchadski R et al. Convergence insufficiency in brain-injured patients. Brain Inj 1989; 3: 187–191.
   PubMedGoogle Scholar
• Ivancevic VG. New mechanics of traumatic brain injury. Cogn Neurodyn 2009; 3: 281.
   PubMed Web of Science ®Google Scholar
• Scheiman M, Gallaway M, Frantz KA et al. Nearpoint of convergence: test procedure, target selection, and normative data. Optom Vis Sci 2003; 80: 214–225.
   PubMed Web of Science ®Google Scholar
• Poltavski D V., Biberdorf D. Screening for lifetime concussion in athletes: importance of oculomotor measures. Brain Inj 2014; 28: 475–485.
   PubMed Web of Science ®Google Scholar
• DuPrey KM, Webner D, Lyons A et al. Convergence insufficiency identifies athletes at risk of prolonged recovery from sport-related concussion. Am J Sports Med 2017; 45: 2388–2393.
   PubMed Web of Science ®Google Scholar
• Pogson JM, Taylor RL, Bradshaw AP et al. The human vestibulo-ocular reflex and saccades: normal subjects and the effect of age. J Neurophysiol 2019; 122: 336–349.
   PubMed Web of Science ®Google Scholar
• Weber KP, Aw ST, Todd MJ et al. Head impulse test in unilateral vestibular loss: vestibulo-ocular reflex and catch-up saccades. Neurology 2008; 70: 454–463.
   PubMed Web of Science ®Google Scholar
• Halmagyi GM, Curthoys IS. A clinical sign of canal paresis. Arch Neurol 1988; 45: 737–739.
   PubMed Web of Science ®Google Scholar
• Correia MJ, Hixson WC, Niven JI. Kinematics nomenclature for physiological accelerations with special reference to vestibular applications. Pensacola; 1966. Accessed 11 September 2020. https://ntrs.nasa.gov/archive/nasa/casi.ntrs.nasa.gov/19670014002.pdf
   Google Scholar
• Hougaard DD, Abrahamsen ER. Functional testing of all six semicircular canals with video head impulse test systems. J Vis Exp 2019; 2019: e59012.
   Google Scholar
• Sjögren J, Fransson P-A, Karlberg M et al. Functional head impulse testing might be useful for assessing vestibular compensation after unilateral vestibular loss. Front Neurol 2018; 9: 979.
   PubMed Web of Science ®Google Scholar
• Scherer MR, Shelhamer MJ, Schubert MC. Characterizing high-velocity angular vestibulo-ocular reflex function in service members post-blast exposure. Exp Brain Res 2011; 208: 399–410.
   PubMed Web of Science ®Google Scholar
• Schubert MC, Migliaccio AA. Stability of the aVOR to repeat head impulse testing. Otol Neurotol 2016; 37: 781–786.
   PubMed Web of Science ®Google Scholar
• Doustkouhi SM, Turnbull PRK, Dakin SC. The effect of simulated visual field loss on optokinetic nystagmus. Transl Vis Sci Technol Epub ahead of print 2020; 9. doi:10.1167/tvst.9.3.25.
   PubMed Web of Science ®Google Scholar
• Dakin S, Turnbull P. Similar estimates of contrast sensitivity and acuity from psychophysics and automated analysis of optokinetic nystagmus. J Vis 2016; 16: 1331–1332.
   Google Scholar
• Wright WG, Tierney RT, McDevitt J. Visual-vestibular processing deficits in mild traumatic brain injury. J Vestib Res Equilib Orientat 2017; 27: 27–37.
   PubMed Web of Science ®Google Scholar
• Cohen B, Yakushin SB, Cho C. Hypothesis: the vestibular and cerebellar basis of the Mal de Debarquement syndrome. Front Neurol 2018: 28.
   PubMed Web of Science ®Google Scholar
• Vakil E, Weisz H, Jedwab L et al. Stroop color-word task as a measure of selective attention: efficiency in closed-head-injured patients. J Clin Exp Neuropsychol 1995; 17: 335–342.
   PubMed Web of Science ®Google Scholar
• Treleaven Jull, LowChoy. The relationship of cervical joint position error to balance and eye movement disturbances in persistent whiplash. Man Ther 2006; 11: 99–106.
   PubMed Web of Science ®Google Scholar
• Donohue SE, Appelbaum LG, Park CJ et al. Cross-modal stimulus conflict: the behavioral effects of stimulus input timing in a visual-auditory stroop task. PLoS One 2013; 8: e62802.
   PubMed Web of Science ®Google Scholar
• Dimoska-Di Marco A, McDonald S, Kelly M et al. A meta-analysis of response inhibition and Stroop interference control deficits in adults with traumatic brain injury (TBI). J Clin Exp Neuropsychol 2011; 33: 471–485.
   PubMed Web of Science ®Google Scholar
• Padula W V, Capo-Aponte JE, Singman EL et al. Brain injury the consequence of spatial visual processing dysfunction caused by traumatic brain injury (TBI) The consequence of spatial visual processing dysfunction caused by traumatic brain injury (TBI). Brain Inj. 31:589-600. Epub ahead of print. 2017. doi:10.1080/02699052.2017.1291991.
   Google Scholar
• Adams RA, Perrinet LU, Friston K. Smooth pursuit and visual occlusion: active inference and oculomotor control in schizophrenia. PLoS One 2012; 7: e47502.
   PubMed Web of Science ®Google Scholar
• Vallar G, Lobel E, Galati G et al. A fronto-parietal system for computing the egocentric spatial frame of reference in humans. Exp Brain Res 1999; 124: 281–286.
   PubMed Web of Science ®Google Scholar
• Slobounov SM, Zhang K, Pennell D et al. Functional abnormalities in normally appearing athletes following mild traumatic brain injury: a functional MRI study. Exp Brain Res 2010; 202: 341–354.
   PubMed Web of Science ®Google Scholar
• Ciuffreda KJ, Ludlam P. Egocentric localization: normal and abnormal aspects. In: Harvey L, Suter PS, editors. Vision Rehabilitation: Multidisciplinary Care of the Patient Following Brain Injury. 10th ed. Boca Raton: Taylor and Francis; 2011. p. 193–211.
   Google Scholar
• Luauté J, Michel C, Rode G et al. Functional anatomy of the therapeutic effects of prism adaptation on left neglect. Neurology 2006; 66: 1859–1867.
   PubMed Web of Science ®Google Scholar
• Kapoor N, Ciuffreda KJ, Harris G et al. A new portable clinical device measuring egocentric localization. J Behav Optom 2001; 12: 115–119.
   Google Scholar
• Chokron S, Bartolomeo P. Correlation between the position of the egocentric reference and right neglect signs in left-brain-damaged patients. Brain Cogn 2000; 43: 99–104.
   PubMed Web of Science ®Google Scholar
• Ho K, F M, N M. Disentangling gravitational, environmental, and egocentric reference frames in spatial neglect. J Cogn Neurosci 1998; 10: 680–690.
   PubMed Web of Science ®Google Scholar
• Zhou Y, Li B, Wang G et al. Leftward deviation and asymmetric speed of egocentric judgment between left and right visual fields. Front Neurosci 2017; 11: 364.
   PubMed Web of Science ®Google Scholar
• Funke G, Greenlee E, Carter M et al. Which eye tracker is right for your research? Performance evaluation of several cost variant eye trackers. Proc Human Factors Ergonom Soc Annu Meet. 2016;60:1239–1243.
   Google Scholar
• Niehorster DC, Cornelissen THW, Holmqvist K et al. What to expect from your remote eye-tracker when participants are unrestrained. Behav Res Methods 2018; 50: 213–227.
   PubMed Web of Science ®Google Scholar
• Dalmaijer E. Is the low-cost EyeTribe eye tracker any good for research? PeerJ Pre Prints. 2014;2:585.
   Google Scholar
• Ooms K, Dupont L, Lapon L et al. Accuracy and precision of fixation locations recorded with the low-cost Eye Tribe tracker in different experimental setups. J Eye Mov Res. 2015;8:1–24.
   Web of Science ®Google Scholar
• Cuve HC, Stojanov J, Roberts-Gaal X et al. Validation of Gazepoint low-cost eye-tracking and psychophysiology bundle. Behav Res Meth 2021;53:1–23.
   PubMedGoogle Scholar
• Doustkouhi SM, Turnbull PRK, Dakin SC. The effect of refractive error on optokinetic nystagmus. Sci Rep 2020; 10: 1–14.
   PubMed Web of Science ®Google Scholar
• Turnbull PRK, Phillips JR. Ocular effects of virtual reality headset wear in young adults. Sci Rep 2017; 7: 16172.
   PubMed Web of Science ®Google Scholar